DE69730314T2 - Dosierungsform von ibuprofen - Google Patents

Dosierungsform von ibuprofen Download PDF

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Publication number
DE69730314T2
DE69730314T2 DE69730314T DE69730314T DE69730314T2 DE 69730314 T2 DE69730314 T2 DE 69730314T2 DE 69730314 T DE69730314 T DE 69730314T DE 69730314 T DE69730314 T DE 69730314T DE 69730314 T2 DE69730314 T2 DE 69730314T2
Authority
DE
Germany
Prior art keywords
dosage form
ibuprofen
weight
bicarbonate
component
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69730314T
Other languages
German (de)
English (en)
Other versions
DE69730314D1 (de
Inventor
Ashley Ian PRICE
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Reckitt Benckiser Healthcare UK Ltd
Original Assignee
Boots Co PLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boots Co PLC filed Critical Boots Co PLC
Publication of DE69730314D1 publication Critical patent/DE69730314D1/de
Application granted granted Critical
Publication of DE69730314T2 publication Critical patent/DE69730314T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2009—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Inorganic Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DE69730314T 1996-02-21 1997-02-19 Dosierungsform von ibuprofen Expired - Lifetime DE69730314T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB9603699 1996-02-21
GBGB9603699.1A GB9603699D0 (en) 1996-02-21 1996-02-21 Therapeutic composition
PCT/EP1997/000841 WO1997030699A2 (en) 1996-02-21 1997-02-19 Dosage form of ibuprofen

Publications (2)

Publication Number Publication Date
DE69730314D1 DE69730314D1 (de) 2004-09-23
DE69730314T2 true DE69730314T2 (de) 2005-08-18

Family

ID=10789176

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69730314T Expired - Lifetime DE69730314T2 (de) 1996-02-21 1997-02-19 Dosierungsform von ibuprofen

Country Status (25)

Country Link
US (1) US20020034540A1 (OSRAM)
EP (1) EP0881899B1 (OSRAM)
JP (2) JP2000507922A (OSRAM)
KR (1) KR19990087084A (OSRAM)
CN (1) CN1215989A (OSRAM)
AT (1) ATE273696T1 (OSRAM)
AU (1) AU722991B2 (OSRAM)
BG (1) BG64165B1 (OSRAM)
CA (1) CA2246344C (OSRAM)
CZ (1) CZ298371B6 (OSRAM)
DE (1) DE69730314T2 (OSRAM)
DK (1) DK0881899T3 (OSRAM)
ES (1) ES2227670T3 (OSRAM)
GB (1) GB9603699D0 (OSRAM)
HU (1) HUP9901454A3 (OSRAM)
IL (1) IL125803A0 (OSRAM)
NO (1) NO983825L (OSRAM)
NZ (1) NZ331416A (OSRAM)
PL (1) PL187383B1 (OSRAM)
PT (1) PT881899E (OSRAM)
RU (1) RU2182000C2 (OSRAM)
SK (1) SK285032B6 (OSRAM)
UA (1) UA55407C2 (OSRAM)
WO (1) WO1997030699A2 (OSRAM)
ZA (1) ZA971446B (OSRAM)

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IT1301966B1 (it) * 1998-07-30 2000-07-20 Zambon Spa Composizioni farmaceutiche ad attivita' analgesica
US20030026835A1 (en) * 1999-02-15 2003-02-06 Sumitomo Pharmaceuticals Company Limited Tablets disintegrating rapidly in the oral cavity
US6368618B1 (en) 1999-07-01 2002-04-09 The University Of Georgia Research Foundation, Inc. Composition and method for enhanced transdermal absorption of nonsteroidal anti-inflammatory drugs
NZ508292A (en) * 1999-11-24 2002-08-28 Mcneil Ppc Inc Treatment of migraine symptoms with ibuprofen and salts thereof
KR100523242B1 (ko) * 2000-05-18 2005-10-24 한미약품 주식회사 이부프로펜을 함유하는 정제 조성물
US20030008003A1 (en) * 2001-04-10 2003-01-09 Fahkreddin Jamali Compositions for enhanced absorption of NSAIDs
CH693586A8 (de) * 2002-10-14 2003-12-15 Roche Consumer Health Ag Darreichungsform von Ibuprofen-Natrium.
US9492388B2 (en) * 2002-12-20 2016-11-15 St. James Associates Llc/Faber Research Series Coated particles for sustained-release pharmaceutical administration
US20040176234A1 (en) * 2003-03-07 2004-09-09 Baker Hughes Incorporated Method for improving separation operation of centrifuges and associated improved separation designs
US20080020042A1 (en) * 2003-10-14 2008-01-24 Peter Gruber Dosage form of sodium ibuprofen
UY28583A1 (es) * 2003-10-30 2005-05-31 Roche Consumer Health Ag Forma de presentación del naproxeno sodico
US20050266031A1 (en) 2004-05-25 2005-12-01 Jay Dickerson Pharmaceutical suspension composition
US8216610B2 (en) * 2004-05-28 2012-07-10 Imaginot Pty Ltd. Oral paracetamol formulations
EP3216445A1 (en) * 2004-05-28 2017-09-13 Imaginot Pty Ltd. Oral therapeutic compound delivery system
CA2572359C (en) * 2004-06-29 2010-08-03 Nycomed Danmark Aps Manufacturing of quick release pharmaceutical compositions of water insoluble drugs and pharmaceutical compositions obtained by the process of the invention
WO2006016125A1 (en) * 2004-08-12 2006-02-16 Reckitt Benckiser Healthcare (Uk) Limited Granules comprising a nsaid and a sugar alcohol made by melt extrusion
US20060068009A1 (en) * 2004-09-30 2006-03-30 Scolr Pharma, Inc. Modified release ibuprofen dosage form
US20070077297A1 (en) * 2004-09-30 2007-04-05 Scolr Pharma, Inc. Modified release ibuprofen dosage form
ZA200702694B (en) * 2004-09-30 2008-07-30 Scolr Pharma Inc Modified release ibuprofen dosage form
CA2589079A1 (en) * 2004-11-03 2006-06-01 Equitech Corporation Nsaid compositions exhibiting clinical superiority
EP1850834B1 (de) * 2005-02-09 2014-08-20 Boehringer Ingelheim International GmbH Filmtabletten enthaltend ibuprofen-lysinat
CA2602392A1 (en) 2005-03-22 2006-09-28 Losan Pharma Gmbh Solubilized ibuprofen
EP1800667A1 (en) 2005-12-23 2007-06-27 Losan Pharma GmbH Rapidly solubilizing ibuprofen granulate
CA2622704A1 (en) * 2005-09-19 2007-03-29 Albemarle Corporation Highly concentrated pourable aqueous solutions of potassium ibuprofen their preparation and their uses
US7811604B1 (en) 2005-11-14 2010-10-12 Barr Laboratories, Inc. Non-effervescent, orally disintegrating solid pharmaceutical dosage forms comprising clozapine and methods of making and using the same
EP3263117A1 (en) 2005-11-28 2018-01-03 Imaginot Pty Ltd. Oral therapeutic compound delivery system
KR101288924B1 (ko) * 2006-08-16 2013-07-24 에스에스 세야쿠 가부시키 가이샤 경구투여용 제제
FI20070521A7 (fi) 2006-11-10 2008-05-11 Atacama Labs Oy Rakeita, tabletteja ja rakeistusmenetelmä
US8951562B2 (en) 2006-11-10 2015-02-10 Atacama Labs Oy Method and apparatus or dry granulation
FI20080348A0 (fi) * 2008-02-15 2008-05-09 Atacama Labs Oy Uudenlainen farmaseuttinen formulaatio
US7749537B2 (en) 2006-12-04 2010-07-06 Scolr Pharma, Inc. Method of forming a tablet
WO2008079245A2 (en) * 2006-12-20 2008-07-03 Duramed Pharmaceuticals, Inc. Orally disintegrating solid dosage forms comprising progestin and methods of making and use thereof
EP2291233B1 (en) * 2008-05-09 2019-09-04 Atacama Labs Oy Method for dry granulation
MX337488B (es) 2008-07-21 2016-03-08 Si Group Inc Granulos con alto contenido de ibuprofeno sodico, su preparacion y su uso en preparar formas de dosificacion solidas no efervescentes.
US9629809B2 (en) 2008-07-21 2017-04-25 Si Group, Inc. High content sodium ibuprofen granules, their preparation and their use in preparing non-effervescent solid dosage forms
WO2011001228A1 (en) * 2008-08-14 2011-01-06 Shasun Chemicals And Drugs Limited Aryl alkyl carboxylic acid salts, process for preparation and dosage forms
AU2014200704C1 (en) * 2009-06-22 2018-12-06 Pf Consumer Healthcare 1 Llc Sodium ibuprofen tablets and methods of manufacturing pharmaceutical compositions including sodium ibuprofen
CA2764740C (en) * 2009-06-22 2015-09-01 Wyeth Llc Sodium ibuprofen tablets and methods of manufacturing pharmaceutical compositions including sodium ibuprofen
AU2015264861C1 (en) * 2009-06-22 2017-11-16 Pf Consumer Healthcare 1 Llc Sodium ibuprofen tablets and methods of manufacturing pharmaceutical compositions including sodium ibuprofen
JP5974469B2 (ja) * 2010-12-24 2016-08-23 ライオン株式会社 錠剤の製造方法
CN103102259B (zh) * 2011-12-23 2014-02-26 海南正瑞医药科技开发有限公司 一种布洛芬水合物晶体、及含该水合物晶体的药物组合物及其制备方法
KR101890649B1 (ko) * 2013-07-30 2018-09-28 라이온 가부시키가이샤 정제
EP2845850A1 (en) 2013-09-10 2015-03-11 ObsEva S.A. Pyrrolidine derivatives as oxytocin/vasopressin V1a receptors antagonists
EP2886107A1 (en) 2013-12-17 2015-06-24 ObsEva S.A. Oral formulations of pyrrolydine derivatives
MX371068B (es) 2014-07-02 2020-01-15 ObsEva SA ((3z,5s)-5-(hidroximetil)-1-[(2'-metil-1,1'-bifenil-4-il)carbonil ]pirrolidin-3-ona o-metiloxima cristalina y métodos de uso de la misma.
EP2965746B1 (en) 2014-07-10 2019-03-13 Santa Farma Ilaç Sanayi A.S. An oral pharmaceutical composition comprising ibuprofen, ibuprofen sodium dihydrate, pseudoephedrine hydrochloride and chlorpheniramine maleate
WO2017060920A1 (en) * 2015-10-05 2017-04-13 Strides Shasun Limited Pharmaceutical compositions

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4681897A (en) * 1984-01-16 1987-07-21 The Procter & Gamble Company Pharmaceutical products providing enhanced analgesia
DE3440288C2 (de) * 1984-11-05 1987-03-12 Gergely, Gerhard, Dr.-Ing., Wien Pharmazeutische Zubereitung mit einem Gehalt an Ibuprofen sowie Verfahren zu ihrer Herstellung
US4684666A (en) * 1986-08-19 1987-08-04 Haas Pharmaceuticals, Inc. Stabilized liquid analgesic compositions
AU8320387A (en) * 1986-10-22 1988-05-25 Upjohn Company, The Treatment of gingivitis with ibuprofen or flurbiprofen
US4788220A (en) * 1987-07-08 1988-11-29 American Home Products Corporation (Del.) Pediatric ibuprofen compositions
US4837031A (en) * 1987-09-17 1989-06-06 Mallinckrodt, Inc. Compositions containing ibuprofen
DE3922441A1 (de) * 1989-07-07 1991-01-17 Pharmatrans Sanaq Ag Ibuprofen- und s-(+)-ibuprofen-zubereitungen und verfahren zu ihrer herstellung
SK279279B6 (sk) * 1991-05-13 1998-09-09 The Boots Company Plc S(-)-nátrium-2-(4-izobutylfenyl)propionát-dihydrát
DE4216756C2 (de) * 1992-05-21 1994-08-25 Pharmatrans Sanaq Ag 2-Arylpropionsäure-Zubereitungen und Verfahren zu ihrer Herstellung
ES2134796T3 (es) * 1992-12-01 1999-10-16 Spirig Ag Pharmazeutische Prap Composiciones farmaceuticas que contienen s(+)-ibuprofeno.

Also Published As

Publication number Publication date
ES2227670T3 (es) 2005-04-01
PT881899E (pt) 2004-12-31
SK114298A3 (en) 1999-01-11
CA2246344A1 (en) 1997-08-28
CN1215989A (zh) 1999-05-05
DE69730314D1 (de) 2004-09-23
WO1997030699A3 (en) 1997-10-09
AU722991B2 (en) 2000-08-17
EP0881899B1 (en) 2004-08-18
NZ331416A (en) 2000-02-28
PL187383B1 (pl) 2004-06-30
DK0881899T3 (da) 2004-12-20
ATE273696T1 (de) 2004-09-15
NO983825L (no) 1998-10-20
UA55407C2 (uk) 2003-04-15
BG102744A (bg) 1999-05-31
HUP9901454A3 (en) 2001-04-28
AU1793797A (en) 1997-09-10
ZA971446B (en) 1997-11-25
BG64165B1 (bg) 2004-03-31
EP0881899A2 (en) 1998-12-09
CA2246344C (en) 2009-01-20
US20020034540A1 (en) 2002-03-21
KR19990087084A (ko) 1999-12-15
RU2182000C2 (ru) 2002-05-10
IL125803A0 (en) 1999-04-11
HUP9901454A2 (hu) 1999-08-30
SK285032B6 (sk) 2006-05-04
CZ261798A3 (cs) 1998-11-11
PL328465A1 (en) 1999-02-01
JP2000507922A (ja) 2000-06-27
CZ298371B6 (cs) 2007-09-12
NO983825D0 (no) 1998-08-20
GB9603699D0 (en) 1996-04-17
WO1997030699A2 (en) 1997-08-28
JP2009073847A (ja) 2009-04-09

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: RECKITT BENCKISER HEALTHCARE INTERNATIONAL LTD, GB

8327 Change in the person/name/address of the patent owner

Owner name: RECKITT BENCKISER HEALTHCARE (UK) LTD., SLOUGH, GB