DE69700935D1 - Energieübertragungsfarbstoffe mit verbesserter Fluoreszenz - Google Patents

Energieübertragungsfarbstoffe mit verbesserter Fluoreszenz

Info

Publication number
DE69700935D1
DE69700935D1 DE69700935T DE69700935T DE69700935D1 DE 69700935 D1 DE69700935 D1 DE 69700935D1 DE 69700935 T DE69700935 T DE 69700935T DE 69700935 T DE69700935 T DE 69700935T DE 69700935 D1 DE69700935 D1 DE 69700935D1
Authority
DE
Germany
Prior art keywords
dye
energy transfer
donor
linkers
acceptor
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69700935T
Other languages
English (en)
Other versions
DE69700935T2 (de
Inventor
Linda G Lee
Sandra L Spurgeon
Barnett Rosenblum
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Applied Biosystems LLC
Original Assignee
Perkin Elmer Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/642,330 external-priority patent/US5863727A/en
Application filed by Perkin Elmer Corp filed Critical Perkin Elmer Corp
Publication of DE69700935D1 publication Critical patent/DE69700935D1/de
Application granted granted Critical
Publication of DE69700935T2 publication Critical patent/DE69700935T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09B—ORGANIC DYES OR CLOSELY-RELATED COMPOUNDS FOR PRODUCING DYES, e.g. PIGMENTS; MORDANTS; LAKES
    • C09B11/00—Diaryl- or thriarylmethane dyes
    • C09B11/04—Diaryl- or thriarylmethane dyes derived from triarylmethanes, i.e. central C-atom is substituted by amino, cyano, alkyl
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09B—ORGANIC DYES OR CLOSELY-RELATED COMPOUNDS FOR PRODUCING DYES, e.g. PIGMENTS; MORDANTS; LAKES
    • C09B11/00—Diaryl- or thriarylmethane dyes
    • C09B11/04—Diaryl- or thriarylmethane dyes derived from triarylmethanes, i.e. central C-atom is substituted by amino, cyano, alkyl
    • C09B11/06—Hydroxy derivatives of triarylmethanes in which at least one OH group is bound to an aryl nucleus and their ethers or esters
    • C09B11/08—Phthaleins; Phenolphthaleins; Fluorescein
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09B—ORGANIC DYES OR CLOSELY-RELATED COMPOUNDS FOR PRODUCING DYES, e.g. PIGMENTS; MORDANTS; LAKES
    • C09B11/00—Diaryl- or thriarylmethane dyes
    • C09B11/04—Diaryl- or thriarylmethane dyes derived from triarylmethanes, i.e. central C-atom is substituted by amino, cyano, alkyl
    • C09B11/10—Amino derivatives of triarylmethanes
    • C09B11/24—Phthaleins containing amino groups ; Phthalanes; Fluoranes; Phthalides; Rhodamine dyes; Phthaleins having heterocyclic aryl rings; Lactone or lactame forms of triarylmethane dyes
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09B—ORGANIC DYES OR CLOSELY-RELATED COMPOUNDS FOR PRODUCING DYES, e.g. PIGMENTS; MORDANTS; LAKES
    • C09B23/00—Methine or polymethine dyes, e.g. cyanine dyes
    • C09B23/02—Methine or polymethine dyes, e.g. cyanine dyes the polymethine chain containing an odd number of >CH- or >C[alkyl]- groups
    • C09B23/08—Methine or polymethine dyes, e.g. cyanine dyes the polymethine chain containing an odd number of >CH- or >C[alkyl]- groups more than three >CH- groups, e.g. polycarbocyanines
    • C09B23/083—Methine or polymethine dyes, e.g. cyanine dyes the polymethine chain containing an odd number of >CH- or >C[alkyl]- groups more than three >CH- groups, e.g. polycarbocyanines five >CH- groups
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09B—ORGANIC DYES OR CLOSELY-RELATED COMPOUNDS FOR PRODUCING DYES, e.g. PIGMENTS; MORDANTS; LAKES
    • C09B69/00—Dyes not provided for by a single group of this subclass
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6869—Methods for sequencing
DE69700935T 1996-05-03 1997-05-02 Energieübertragungsfarbstoffe mit verbesserter Fluoreszenz Expired - Lifetime DE69700935T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/642,330 US5863727A (en) 1996-05-03 1996-05-03 Energy transfer dyes with enhanced fluorescence
US08/726,462 US5800996A (en) 1996-05-03 1996-10-04 Energy transfer dyes with enchanced fluorescence

Publications (2)

Publication Number Publication Date
DE69700935D1 true DE69700935D1 (de) 2000-01-20
DE69700935T2 DE69700935T2 (de) 2000-04-27

Family

ID=27093992

Family Applications (2)

Application Number Title Priority Date Filing Date
DE69700935T Expired - Lifetime DE69700935T2 (de) 1996-05-03 1997-05-02 Energieübertragungsfarbstoffe mit verbesserter Fluoreszenz
DE69736434T Expired - Lifetime DE69736434T2 (de) 1996-05-03 1997-05-02 Energieübertragungsfarbstoffe mit verbesserter Fluoreszenz

Family Applications After (1)

Application Number Title Priority Date Filing Date
DE69736434T Expired - Lifetime DE69736434T2 (de) 1996-05-03 1997-05-02 Energieübertragungsfarbstoffe mit verbesserter Fluoreszenz

Country Status (6)

Country Link
US (1) US5800996A (de)
EP (2) EP0805190B1 (de)
JP (8) JP3090626B2 (de)
AT (2) ATE335051T1 (de)
CA (1) CA2203494C (de)
DE (2) DE69700935T2 (de)

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JP2000154332A (ja) 2000-06-06
DE69700935T2 (de) 2000-04-27
JP2000187036A (ja) 2000-07-04
EP0805190B1 (de) 1999-12-15
AU691143B2 (en) 1998-05-07
JP3090626B2 (ja) 2000-09-25
EP0805190A3 (de) 1998-01-07
JP2004068023A (ja) 2004-03-04
EP0940450B1 (de) 2006-08-02
EP0805190A2 (de) 1997-11-05
ATE335051T1 (de) 2006-08-15
JP2004250713A (ja) 2004-09-09
JP3592173B2 (ja) 2004-11-24
EP0940450A1 (de) 1999-09-08
DE69736434D1 (de) 2006-09-14
ATE187752T1 (de) 2000-01-15
US5800996A (en) 1998-09-01
JP3499238B2 (ja) 2004-02-23
JP2004043819A (ja) 2004-02-12
JP2000154381A (ja) 2000-06-06
JPH1088124A (ja) 1998-04-07
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CA2203494C (en) 2000-12-26
JP2003274999A (ja) 2003-09-30
CA2203494A1 (en) 1997-11-03

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