SG11201704098VA - Enzyme- and amplification-free sequencing - Google Patents
Enzyme- and amplification-free sequencingInfo
- Publication number
- SG11201704098VA SG11201704098VA SG11201704098VA SG11201704098VA SG11201704098VA SG 11201704098V A SG11201704098V A SG 11201704098VA SG 11201704098V A SG11201704098V A SG 11201704098VA SG 11201704098V A SG11201704098V A SG 11201704098VA SG 11201704098V A SG11201704098V A SG 11201704098VA
- Authority
- SG
- Singapore
- Prior art keywords
- amplification
- enzyme
- free sequencing
- sequencing
- free
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6869—Methods for sequencing
- C12Q1/6874—Methods for sequencing involving nucleic acid arrays, e.g. sequencing by hybridisation
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6869—Methods for sequencing
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2525/00—Reactions involving modified oligonucleotides, nucleic acids, or nucleotides
- C12Q2525/10—Modifications characterised by
- C12Q2525/113—Modifications characterised by incorporating modified backbone
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2537/00—Reactions characterised by the reaction format or use of a specific feature
- C12Q2537/10—Reactions characterised by the reaction format or use of a specific feature the purpose or use of
- C12Q2537/149—Sequential reactions
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2563/00—Nucleic acid detection characterized by the use of physical, structural and functional properties
- C12Q2563/179—Nucleic acid detection characterized by the use of physical, structural and functional properties the label being a nucleic acid
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Analytical Chemistry (AREA)
- Physics & Mathematics (AREA)
- Immunology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201462082883P | 2014-11-21 | 2014-11-21 | |
PCT/US2015/061615 WO2016081740A1 (en) | 2014-11-21 | 2015-11-19 | Enzyme- and amplification-free sequencing |
Publications (1)
Publication Number | Publication Date |
---|---|
SG11201704098VA true SG11201704098VA (en) | 2017-06-29 |
Family
ID=54705918
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG11201704098VA SG11201704098VA (en) | 2014-11-21 | 2015-11-19 | Enzyme- and amplification-free sequencing |
Country Status (10)
Country | Link |
---|---|
US (4) | US20160194701A1 (en) |
EP (3) | EP3696280B1 (en) |
JP (4) | JP6674951B2 (en) |
KR (4) | KR102105236B1 (en) |
CN (2) | CN113403373A (en) |
AU (3) | AU2015349870B2 (en) |
CA (1) | CA2968376C (en) |
ES (2) | ES2770055T3 (en) |
SG (1) | SG11201704098VA (en) |
WO (1) | WO2016081740A1 (en) |
Families Citing this family (68)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP3604555A1 (en) * | 2011-10-14 | 2020-02-05 | President and Fellows of Harvard College | Sequencing by structure assembly |
US11021737B2 (en) | 2011-12-22 | 2021-06-01 | President And Fellows Of Harvard College | Compositions and methods for analyte detection |
EP4108782B1 (en) | 2011-12-22 | 2023-06-07 | President and Fellows of Harvard College | Compositions and methods for analyte detection |
US9914967B2 (en) | 2012-06-05 | 2018-03-13 | President And Fellows Of Harvard College | Spatial sequencing of nucleic acids using DNA origami probes |
EP2971184B1 (en) | 2013-03-12 | 2019-04-17 | President and Fellows of Harvard College | Method of generating a three-dimensional nucleic acid containing matrix |
EP3003392B1 (en) | 2013-06-04 | 2019-10-23 | President and Fellows of Harvard College | Rna-guideded transcriptional regulation |
LT3013983T (en) | 2013-06-25 | 2023-05-10 | Prognosys Biosciences, Inc. | Spatially encoded biological assays using a microfluidic device |
EP4328322A3 (en) | 2014-07-30 | 2024-05-22 | President and Fellows of Harvard College | Probe library construction |
EP4321627A3 (en) | 2015-04-10 | 2024-04-17 | 10x Genomics Sweden AB | Spatially distinguished, multiplex nucleic acid analysis of biological specimens |
CA2992492A1 (en) | 2015-07-17 | 2017-01-26 | Nanostring Technologies, Inc. | Simultaneous quantification of gene expression in a user-defined region of a cross-sectioned tissue |
ES2975361T3 (en) | 2015-07-17 | 2024-07-04 | Nanostring Technologies Inc | Simultaneous quantification of a plurality of proteins in a user-defined region of a cross-sectioned tissue |
AU2016349288A1 (en) | 2015-11-03 | 2018-05-31 | President And Fellows Of Harvard College | Method and apparatus for volumetric imaging of a three-dimensional nucleic acid containing matrix |
CN116200465A (en) | 2016-04-25 | 2023-06-02 | 哈佛学院董事及会员团体 | Hybrid chain reaction method for in situ molecular detection |
SG11201809913PA (en) * | 2016-05-16 | 2018-12-28 | Nanostring Technologies Inc | Methods for detecting target nucleic acids in a sample |
WO2017222453A1 (en) | 2016-06-21 | 2017-12-28 | Hauling Thomas | Nucleic acid sequencing |
WO2018045186A1 (en) | 2016-08-31 | 2018-03-08 | President And Fellows Of Harvard College | Methods of combining the detection of biomolecules into a single assay using fluorescent in situ sequencing |
CN118389650A (en) | 2016-08-31 | 2024-07-26 | 哈佛学院董事及会员团体 | Method for generating a library of nucleic acid sequences for detection by fluorescence in situ sequencing |
CN110225980B (en) | 2016-11-21 | 2023-01-06 | 纳米线科技公司 | Chemical compositions and methods of use thereof |
WO2018138237A1 (en) * | 2017-01-27 | 2018-08-02 | Roche Diagnostics Gmbh | Barcoded dna for long range sequencing |
WO2018218150A1 (en) | 2017-05-26 | 2018-11-29 | President And Fellows Of Harvard College | Systems and methods for high-throughput image-based screening |
WO2019069371A1 (en) * | 2017-10-03 | 2019-04-11 | 株式会社ニコン | Method for detecting detection target within subject body, detection kit, and fluid device |
CA3078158A1 (en) | 2017-10-06 | 2019-04-11 | Cartana Ab | Rna templated ligation |
CN110079592B (en) * | 2018-01-26 | 2021-02-12 | 厦门艾德生物医药科技股份有限公司 | High throughput sequencing-targeted capture of target regions for detection of genetic mutations and known, unknown gene fusion types |
CN112154216A (en) | 2018-02-12 | 2020-12-29 | 纳米线科技公司 | Biomolecule probes and methods for detecting gene and protein expression |
CN112703255A (en) * | 2018-05-14 | 2021-04-23 | 纳米线科技公司 | Chemical compositions and methods of use thereof |
SG11202101934SA (en) | 2018-07-30 | 2021-03-30 | Readcoor Llc | Methods and systems for sample processing or analysis |
US11519033B2 (en) | 2018-08-28 | 2022-12-06 | 10X Genomics, Inc. | Method for transposase-mediated spatial tagging and analyzing genomic DNA in a biological sample |
WO2020076976A1 (en) | 2018-10-10 | 2020-04-16 | Readcoor, Inc. | Three-dimensional spatial molecular indexing |
US20220064630A1 (en) | 2018-12-10 | 2022-03-03 | 10X Genomics, Inc. | Resolving spatial arrays using deconvolution |
US11649485B2 (en) | 2019-01-06 | 2023-05-16 | 10X Genomics, Inc. | Generating capture probes for spatial analysis |
US11926867B2 (en) | 2019-01-06 | 2024-03-12 | 10X Genomics, Inc. | Generating capture probes for spatial analysis |
WO2020243579A1 (en) | 2019-05-30 | 2020-12-03 | 10X Genomics, Inc. | Methods of detecting spatial heterogeneity of a biological sample |
CN113906147B (en) | 2019-05-31 | 2024-09-13 | 10X基因组学有限公司 | Method for detecting target nucleic acid molecule |
WO2021092433A2 (en) | 2019-11-08 | 2021-05-14 | 10X Genomics, Inc. | Enhancing specificity of analyte binding |
US20230059203A1 (en) * | 2019-12-19 | 2023-02-23 | Akoya Biosciences, Inc. | RNA Detection |
US20210190770A1 (en) | 2019-12-23 | 2021-06-24 | 10X Genomics, Inc. | Compositions and methods for using fixed biological samples in partition-based assays |
ES2982420T3 (en) | 2019-12-23 | 2024-10-16 | 10X Genomics Inc | Methods for spatial analysis using RNA-templated ligation |
WO2021138078A1 (en) * | 2019-12-30 | 2021-07-08 | President And Fellows Of Harvard College | Genome-scale imaging of the 3d organization and transcriptional activity of chromatin |
US11732299B2 (en) | 2020-01-21 | 2023-08-22 | 10X Genomics, Inc. | Spatial assays with perturbed cells |
US11702693B2 (en) | 2020-01-21 | 2023-07-18 | 10X Genomics, Inc. | Methods for printing cells and generating arrays of barcoded cells |
US12076701B2 (en) | 2020-01-31 | 2024-09-03 | 10X Genomics, Inc. | Capturing oligonucleotides in spatial transcriptomics |
US12110548B2 (en) | 2020-02-03 | 2024-10-08 | 10X Genomics, Inc. | Bi-directional in situ analysis |
US11898205B2 (en) | 2020-02-03 | 2024-02-13 | 10X Genomics, Inc. | Increasing capture efficiency of spatial assays |
US12110541B2 (en) | 2020-02-03 | 2024-10-08 | 10X Genomics, Inc. | Methods for preparing high-resolution spatial arrays |
US11732300B2 (en) | 2020-02-05 | 2023-08-22 | 10X Genomics, Inc. | Increasing efficiency of spatial analysis in a biological sample |
US11891654B2 (en) | 2020-02-24 | 2024-02-06 | 10X Genomics, Inc. | Methods of making gene expression libraries |
CN115916999A (en) | 2020-04-22 | 2023-04-04 | 10X基因组学有限公司 | Methods for spatial analysis using targeted RNA depletion |
CN115803454A (en) * | 2020-05-04 | 2023-03-14 | 10X基因组学有限公司 | Spatial transcriptomics transfer mode |
EP4153775B1 (en) | 2020-05-22 | 2024-07-24 | 10X Genomics, Inc. | Simultaneous spatio-temporal measurement of gene expression and cellular activity |
AU2021275906A1 (en) | 2020-05-22 | 2022-12-22 | 10X Genomics, Inc. | Spatial analysis to detect sequence variants |
WO2021242834A1 (en) | 2020-05-26 | 2021-12-02 | 10X Genomics, Inc. | Method for resetting an array |
US12031177B1 (en) | 2020-06-04 | 2024-07-09 | 10X Genomics, Inc. | Methods of enhancing spatial resolution of transcripts |
EP4421186A3 (en) | 2020-06-08 | 2024-09-18 | 10X Genomics, Inc. | Methods of determining a surgical margin and methods of use thereof |
EP4446430A2 (en) | 2020-06-10 | 2024-10-16 | 10X Genomics, Inc. | Methods for determining a location of an analyte in a biological sample |
WO2021263111A1 (en) | 2020-06-25 | 2021-12-30 | 10X Genomics, Inc. | Spatial analysis of dna methylation |
US11761038B1 (en) | 2020-07-06 | 2023-09-19 | 10X Genomics, Inc. | Methods for identifying a location of an RNA in a biological sample |
US11981960B1 (en) | 2020-07-06 | 2024-05-14 | 10X Genomics, Inc. | Spatial analysis utilizing degradable hydrogels |
US11981958B1 (en) | 2020-08-20 | 2024-05-14 | 10X Genomics, Inc. | Methods for spatial analysis using DNA capture |
US11926822B1 (en) | 2020-09-23 | 2024-03-12 | 10X Genomics, Inc. | Three-dimensional spatial analysis |
US12071667B2 (en) | 2020-11-04 | 2024-08-27 | 10X Genomics, Inc. | Sequence analysis using meta-stable nucleic acid molecules |
US11827935B1 (en) | 2020-11-19 | 2023-11-28 | 10X Genomics, Inc. | Methods for spatial analysis using rolling circle amplification and detection probes |
EP4121555A1 (en) | 2020-12-21 | 2023-01-25 | 10X Genomics, Inc. | Methods, compositions, and systems for capturing probes and/or barcodes |
US12060603B2 (en) | 2021-01-19 | 2024-08-13 | 10X Genomics, Inc. | Methods for internally controlled in situ assays using padlock probes |
WO2022256503A1 (en) | 2021-06-03 | 2022-12-08 | 10X Genomics, Inc. | Methods, compositions, kits, and systems for enhancing analyte capture for spatial analysis |
WO2023034489A1 (en) | 2021-09-01 | 2023-03-09 | 10X Genomics, Inc. | Methods, compositions, and kits for blocking a capture probe on a spatial array |
US12116626B2 (en) | 2022-08-16 | 2024-10-15 | 10X Genomics, Inc. | AP50 polymerases and uses thereof |
WO2024196764A2 (en) | 2023-03-17 | 2024-09-26 | Nanostring Technologies, Inc. | Assay for recombinase accessible chromatin and related compositions and methods |
WO2024196728A2 (en) | 2023-03-17 | 2024-09-26 | Nanostring Technologies, Inc. | Nucleic acid probes for combined sequencing and spatial analysis |
Family Cites Families (50)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4230558A (en) | 1978-10-02 | 1980-10-28 | Coulter Electronics, Inc. | Single drop separator |
US4318846A (en) | 1979-09-07 | 1982-03-09 | Syva Company | Novel ether substituted fluorescein polyamino acid compounds as fluorescers and quenchers |
US4757141A (en) | 1985-08-26 | 1988-07-12 | Applied Biosystems, Incorporated | Amino-derivatized phosphite and phosphate linking agents, phosphoramidite precursors, and useful conjugates thereof |
US5091519A (en) | 1986-05-01 | 1992-02-25 | Amoco Corporation | Nucleotide compositions with linking groups |
US4811218A (en) | 1986-06-02 | 1989-03-07 | Applied Biosystems, Inc. | Real time scanning electrophoresis apparatus for DNA sequencing |
US5151507A (en) | 1986-07-02 | 1992-09-29 | E. I. Du Pont De Nemours And Company | Alkynylamino-nucleotides |
US5066580A (en) | 1988-08-31 | 1991-11-19 | Becton Dickinson And Company | Xanthene dyes that emit to the red of fluorescein |
US5366860A (en) | 1989-09-29 | 1994-11-22 | Applied Biosystems, Inc. | Spectrally resolvable rhodamine dyes for nucleic acid sequence determination |
US5188934A (en) | 1989-11-14 | 1993-02-23 | Applied Biosystems, Inc. | 4,7-dichlorofluorescein dyes as molecular probes |
US5654419A (en) | 1994-02-01 | 1997-08-05 | The Regents Of The University Of California | Fluorescent labels and their use in separations |
US5800996A (en) | 1996-05-03 | 1998-09-01 | The Perkin Elmer Corporation | Energy transfer dyes with enchanced fluorescence |
US5847162A (en) | 1996-06-27 | 1998-12-08 | The Perkin Elmer Corporation | 4, 7-Dichlororhodamine dyes |
US6322901B1 (en) | 1997-11-13 | 2001-11-27 | Massachusetts Institute Of Technology | Highly luminescent color-selective nano-crystalline materials |
US6207392B1 (en) | 1997-11-25 | 2001-03-27 | The Regents Of The University Of California | Semiconductor nanocrystal probes for biological applications and process for making and using such probes |
US5990479A (en) | 1997-11-25 | 1999-11-23 | Regents Of The University Of California | Organo Luminescent semiconductor nanocrystal probes for biological applications and process for making and using such probes |
US6426513B1 (en) | 1998-09-18 | 2002-07-30 | Massachusetts Institute Of Technology | Water-soluble thiol-capped nanocrystals |
US6251303B1 (en) | 1998-09-18 | 2001-06-26 | Massachusetts Institute Of Technology | Water-soluble fluorescent nanocrystals |
KR20020007359A (en) * | 1999-04-08 | 2002-01-26 | 추후제출 | Amplification and Sequencing Primer Pairs and Use thereof |
US6649138B2 (en) | 2000-10-13 | 2003-11-18 | Quantum Dot Corporation | Surface-modified semiconductive and metallic nanoparticles having enhanced dispersibility in aqueous media |
US6576291B2 (en) | 2000-12-08 | 2003-06-10 | Massachusetts Institute Of Technology | Preparation of nanocrystallites |
US7473767B2 (en) | 2001-07-03 | 2009-01-06 | The Institute For Systems Biology | Methods for detection and quantification of analytes in complex mixtures |
CA2453450A1 (en) | 2001-07-20 | 2003-11-06 | Quantum Dot Corporation | Luminescent nanoparticles and methods for their preparation |
JP4283578B2 (en) * | 2003-03-31 | 2009-06-24 | 学校法人片柳学園 | Target sequence detection method using probe nucleic acid containing mismatch amplification substance, probe nucleic acid and target sequence detection assay kit |
WO2006031745A2 (en) * | 2004-09-10 | 2006-03-23 | Sequenom, Inc. | Methods for long-range sequence analysis of nucleic acids |
JP4839051B2 (en) * | 2004-10-08 | 2011-12-14 | シスメックス株式会社 | Method for detecting a test substance using a nucleic acid probe |
US20090299640A1 (en) | 2005-11-23 | 2009-12-03 | University Of Utah Research Foundation | Methods and Compositions Involving Intrinsic Genes |
CA2635215C (en) | 2005-12-23 | 2016-08-30 | Nanostring Technologies, Inc. | Compositions comprising oriented, immobilized macromolecules and methods for their preparation |
CA2640385C (en) | 2005-12-23 | 2014-07-15 | Nanostring Technologies, Inc. | Nanoreporters and methods of manufacturing and use thereof |
EP1994180A4 (en) * | 2006-02-24 | 2009-11-25 | Callida Genomics Inc | High throughput genome sequencing on dna arrays |
US7941279B2 (en) | 2006-05-22 | 2011-05-10 | Nanostring Technologies, Inc. | Systems and methods for analyzing nanoreporters |
US7745129B1 (en) * | 2006-07-12 | 2010-06-29 | Kenneth David Schatz | Methods for sequencing of a necleic acid |
AU2008237018B2 (en) | 2007-04-10 | 2014-04-03 | Bruker Spatial Biology, Inc. | Methods and computer systems for identifying target-specific sequences for use in nanoreporters |
ES2457534T3 (en) | 2008-05-30 | 2014-04-28 | The University Of North Carolina At Chapel Hill | Gene expression profiles to predict outcomes in breast cancer |
JP5836803B2 (en) | 2008-08-14 | 2015-12-24 | ナノストリング テクノロジーズ, インコーポレイテッド | Stable nanoreporter |
KR101829182B1 (en) * | 2009-04-02 | 2018-03-29 | 플루이다임 코포레이션 | Multi-primer amplification method for barcoding of target nucleic acids |
JP5954876B2 (en) | 2009-10-13 | 2016-07-20 | ナノストリング テクノロジーズ, インコーポレイテッド | Protein detection by nanoreporter |
WO2011100541A2 (en) | 2010-02-11 | 2011-08-18 | Nanostring Technologies, Inc. | Compositions and methods for the detection of small rnas |
EP2547795B1 (en) | 2010-03-16 | 2015-01-14 | Nanostring Technologies, Inc | Compositions and methods for the detection of genomic features |
AU2012229123B2 (en) | 2011-03-15 | 2017-02-02 | British Columbia Cancer Agency Branch | Methods of treating breast cancer with anthracycline therapy |
US9758834B2 (en) | 2011-03-28 | 2017-09-12 | Nanostring Technologies, Inc. | Compositions and methods for diagnosing cancer |
CN108342453A (en) * | 2011-05-09 | 2018-07-31 | 富鲁达公司 | Detection of nucleic acids based on probe |
US20130017971A1 (en) | 2011-06-24 | 2013-01-17 | Nanostring Technologies, Inc. | Multivariate Diagnostic Assays and Methods for Using Same |
EP3604555A1 (en) | 2011-10-14 | 2020-02-05 | President and Fellows of Harvard College | Sequencing by structure assembly |
EP2785873A4 (en) | 2011-11-30 | 2015-11-11 | Univ North Carolina | Methods of treating breast cancer with taxane therapy |
US10385392B2 (en) * | 2011-12-30 | 2019-08-20 | Abbott Molecular Inc. | Nucleic acid hybridization probes |
EP2852689B1 (en) | 2012-05-22 | 2019-12-11 | Nanostring Technologies, Inc. | Nano46 genes and methods to predict breast cancer outcome |
CA2877378A1 (en) | 2012-06-29 | 2014-01-03 | Nanostring Technologies, Inc. | Methods of treating breast cancer with gemcitabine therapy |
US20140154681A1 (en) | 2012-11-12 | 2014-06-05 | Nanostring Technologies, Inc. | Methods to Predict Breast Cancer Outcome |
CN110225980B (en) * | 2016-11-21 | 2023-01-06 | 纳米线科技公司 | Chemical compositions and methods of use thereof |
CN112703255A (en) * | 2018-05-14 | 2021-04-23 | 纳米线科技公司 | Chemical compositions and methods of use thereof |
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2015
- 2015-11-19 KR KR1020177016946A patent/KR102105236B1/en active IP Right Grant
- 2015-11-19 CA CA2968376A patent/CA2968376C/en active Active
- 2015-11-19 AU AU2015349870A patent/AU2015349870B2/en active Active
- 2015-11-19 CN CN202110629754.3A patent/CN113403373A/en active Pending
- 2015-11-19 EP EP20151469.2A patent/EP3696280B1/en active Active
- 2015-11-19 EP EP15801655.0A patent/EP3221469B1/en active Active
- 2015-11-19 US US14/946,386 patent/US20160194701A1/en not_active Abandoned
- 2015-11-19 KR KR1020227022673A patent/KR20220100098A/en active IP Right Grant
- 2015-11-19 KR KR1020217027822A patent/KR102417849B1/en active IP Right Grant
- 2015-11-19 KR KR1020207011298A patent/KR102298387B1/en active IP Right Grant
- 2015-11-19 ES ES15801655T patent/ES2770055T3/en active Active
- 2015-11-19 ES ES20151469T patent/ES2910099T3/en active Active
- 2015-11-19 SG SG11201704098VA patent/SG11201704098VA/en unknown
- 2015-11-19 CN CN201580073880.8A patent/CN107208144B/en active Active
- 2015-11-19 WO PCT/US2015/061615 patent/WO2016081740A1/en active Application Filing
- 2015-11-19 JP JP2017527209A patent/JP6674951B2/en active Active
- 2015-11-19 EP EP22150167.9A patent/EP4029952A1/en active Pending
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2019
- 2019-08-01 US US16/528,760 patent/US20200010891A1/en not_active Abandoned
- 2019-12-06 AU AU2019275665A patent/AU2019275665B2/en active Active
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2020
- 2020-03-09 JP JP2020040296A patent/JP6959378B2/en active Active
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2021
- 2021-10-06 JP JP2021164668A patent/JP7244601B2/en active Active
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2022
- 2022-07-29 US US17/816,233 patent/US20230160004A1/en not_active Abandoned
- 2022-11-18 AU AU2022271472A patent/AU2022271472A1/en active Pending
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2023
- 2023-02-22 US US18/172,771 patent/US20230183800A1/en active Pending
- 2023-03-09 JP JP2023036774A patent/JP7569404B2/en active Active
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