DE69526936T2 - Benzamide-derivate, zubereitungen die sie erhalten und ihre anwendung - Google Patents

Benzamide-derivate, zubereitungen die sie erhalten und ihre anwendung

Info

Publication number
DE69526936T2
DE69526936T2 DE69526936T DE69526936T DE69526936T2 DE 69526936 T2 DE69526936 T2 DE 69526936T2 DE 69526936 T DE69526936 T DE 69526936T DE 69526936 T DE69526936 T DE 69526936T DE 69526936 T2 DE69526936 T2 DE 69526936T2
Authority
DE
Germany
Prior art keywords
preparations
receive
benzamide derivatives
benzamide
derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Revoked
Application number
DE69526936T
Other languages
English (en)
Other versions
DE69526936D1 (de
Inventor
Jean Francois Rossignol
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Romark Laboratories LC
Original Assignee
Romark Laboratories LC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27397680&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE69526936(T2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from US08/227,033 external-priority patent/US5387598A/en
Priority claimed from US08/301,407 external-priority patent/US5578621A/en
Application filed by Romark Laboratories LC filed Critical Romark Laboratories LC
Application granted granted Critical
Publication of DE69526936D1 publication Critical patent/DE69526936D1/de
Publication of DE69526936T2 publication Critical patent/DE69526936T2/de
Anticipated expiration legal-status Critical
Revoked legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/58—Nitro radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A61K31/426—1,3-Thiazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1635—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
DE69526936T 1994-04-13 1995-04-11 Benzamide-derivate, zubereitungen die sie erhalten und ihre anwendung Revoked DE69526936T2 (de)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US08/227,033 US5387598A (en) 1994-04-13 1994-04-13 Composition and galenic formulation suitable for combatting affections of the lower abdomen
US08/301,407 US5578621A (en) 1994-09-08 1994-09-08 Benzamide derivatives
US38385595A 1995-02-06 1995-02-06
PCT/EP1995/001334 WO1995028393A1 (en) 1994-04-13 1995-04-11 Benzamide derivative, compositions containing said derivative and use thereof

Publications (2)

Publication Number Publication Date
DE69526936D1 DE69526936D1 (de) 2002-07-11
DE69526936T2 true DE69526936T2 (de) 2003-02-20

Family

ID=27397680

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69526936T Revoked DE69526936T2 (de) 1994-04-13 1995-04-11 Benzamide-derivate, zubereitungen die sie erhalten und ihre anwendung

Country Status (24)

Country Link
EP (1) EP0755386B1 (de)
JP (1) JP3224395B2 (de)
KR (2) KR100348440B1 (de)
CN (1) CN1072654C (de)
AP (1) AP645A (de)
AT (1) ATE218557T1 (de)
AU (1) AU689582B2 (de)
BG (1) BG62932B1 (de)
BR (1) BR9507371A (de)
CA (1) CA2187110C (de)
CZ (1) CZ287002B6 (de)
DE (1) DE69526936T2 (de)
DK (1) DK0755386T3 (de)
ES (1) ES2161201T3 (de)
FI (1) FI120258B (de)
HU (1) HUT77404A (de)
NZ (1) NZ284800A (de)
OA (1) OA10463A (de)
PL (1) PL186504B1 (de)
PT (1) PT755386E (de)
RU (1) RU2140915C1 (de)
SI (1) SI0755386T1 (de)
SK (1) SK281949B6 (de)
WO (1) WO1995028393A1 (de)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5856348A (en) * 1994-09-08 1999-01-05 Romark Laboratories, L.C. Method for treatment of trematodes with pharmaceutical compositions of tizoxanide and nitazoxanide
US5968961A (en) 1997-05-07 1999-10-19 Romark Laboratories, L.C. Pharmaceutical compositions of tizoxanide and nitazoxanide
CA2467321A1 (en) 2004-05-14 2005-11-14 Paul J. Santerre Polymeric coupling agents and pharmaceutically-active polymers made therefrom
US8828727B2 (en) 2004-07-21 2014-09-09 Dana-Farber Cancer Institute Lentiviral vectors and uses thereof
UA90864C2 (en) 2004-09-09 2010-06-10 Ромарк Лебораториз, Л.К. Halogenated benzamide derivatives
ES2422556T3 (es) 2006-01-09 2013-09-12 Romark Lab Lc Tratamiento de hepatitis vírica
CA2695517C (en) 2007-08-03 2016-09-20 J. Edward Semple Alkylsulfonyl-substituted thiazolide compounds
CN105853415A (zh) 2009-05-12 2016-08-17 罗马克实验室有限公司 卤代烷基杂芳基苯甲酰胺化合物
JP5932640B2 (ja) 2009-06-26 2016-06-08 ロマーク ラボラトリーズ エル．シー． インフルエンザを治療するための化合物および方法
US8999360B2 (en) * 2009-10-22 2015-04-07 Thomas Julius Borody Compositions and methods for treating extracellular parasitic infections
CN104094927B (zh) * 2013-04-02 2016-06-01 兴邦（武汉）生物科技有限公司 一种处理植物的助剂组合物
TW201630606A (zh) * 2015-01-21 2016-09-01 諾華公司 包含局部藥物之蓋崙（ｇａｌｅｎｉｃ）調配物
CA3087898A1 (en) 2018-02-02 2019-08-08 Ripple Therapeutics Corporation Glass formulations comprising steroid dimers and uses thereof
CA3176134A1 (en) 2020-05-01 2021-11-04 Ripple Therapeutics Corporation Heterodimer compositions and methods for the treatment of ocular disorders
CA3219500A1 (en) * 2021-05-28 2022-12-01 Theodore HENDERSON Treatment using an antiviral compound and nitazoxanide

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1306603A (fr) * 1958-08-14 1962-10-19 Innothera Lab Sa Dérivés thiazoliques et leur procédé de préparation
FR716M (de) * 1960-08-05 1961-08-07
GB1437800A (en) * 1973-08-08 1976-06-03 Phavic Sprl Derivatives of 2-benzamido-5-nitro-thiazoles
FR2435905A1 (fr) * 1978-09-13 1980-04-11 Anvar Nouveaux agents molluscicides derives du benzamido-2 nitro-5 thiazole
US4315018A (en) * 1978-12-07 1982-02-09 Rossignol Jean F Specific parasiticidal use of 2-benzamido-5-nitro-thiazole derivatives
US4447414A (en) * 1982-12-21 1984-05-08 Cutter Laboratories, Inc. Carnivore anthelmintics

Also Published As

Publication number Publication date
ES2161201T1 (es) 2001-12-01
KR100373081B1 (ko) 2003-02-25
SK130796A3 (en) 1997-06-04
ES2161201T3 (es) 2002-12-01
AP9600866A0 (en) 1996-10-31
NZ284800A (en) 1998-02-26
ATE218557T1 (de) 2002-06-15
SK281949B6 (sk) 2001-09-11
HU9602798D0 (en) 1996-12-30
JPH09511997A (ja) 1997-12-02
KR100348440B1 (ko) 2002-11-29
CN1072654C (zh) 2001-10-10
EP0755386A1 (de) 1997-01-29
DK0755386T3 (da) 2002-08-26
PL186504B1 (pl) 2004-01-30
PL316757A1 (en) 1997-02-03
AU2344095A (en) 1995-11-10
OA10463A (en) 2002-04-03
BR9507371A (pt) 1997-09-23
AU689582B2 (en) 1998-04-02
BG62932B1 (bg) 2000-11-30
CA2187110C (en) 2002-03-19
SI0755386T1 (en) 2002-10-31
CA2187110A1 (en) 1995-10-26
PT755386E (pt) 2002-11-29
CN1145621A (zh) 1997-03-19
CZ287002B6 (en) 2000-08-16
DE69526936D1 (de) 2002-07-11
CZ295996A3 (en) 1997-03-12
EP0755386B1 (de) 2002-06-05
FI964031A (fi) 1996-10-08
AP645A (en) 1998-04-24
FI964031A0 (fi) 1996-10-08
HUT77404A (hu) 1998-04-28
RU2140915C1 (ru) 1999-11-10
FI120258B (fi) 2009-08-31
WO1995028393A1 (en) 1995-10-26
BG100884A (en) 1997-07-31
JP3224395B2 (ja) 2001-10-29

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Legal Events

Date Code Title Description
8363 Opposition against the patent
8331 Complete revocation