ATE218557T1 - Benzamide-derivate, zubereitungen die sie erhalten und ihre anwendung - Google Patents

Benzamide-derivate, zubereitungen die sie erhalten und ihre anwendung

Info

Publication number
ATE218557T1
ATE218557T1 AT95917310T AT95917310T ATE218557T1 AT E218557 T1 ATE218557 T1 AT E218557T1 AT 95917310 T AT95917310 T AT 95917310T AT 95917310 T AT95917310 T AT 95917310T AT E218557 T1 ATE218557 T1 AT E218557T1
Authority
AT
Austria
Prior art keywords
preparations obtained
benzamide derivatives
benzamide
derivatives
preparations
Prior art date
Application number
AT95917310T
Other languages
English (en)
Inventor
Jean Francois Rossignol
Original Assignee
Romark Lab Lc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27397680&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE218557(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from US08/227,033 external-priority patent/US5387598A/en
Priority claimed from US08/301,407 external-priority patent/US5578621A/en
Application filed by Romark Lab Lc filed Critical Romark Lab Lc
Application granted granted Critical
Publication of ATE218557T1 publication Critical patent/ATE218557T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/58—Nitro radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A61K31/426—1,3-Thiazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1635—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Food Preservation Except Freezing, Refrigeration, And Drying (AREA)
AT95917310T 1994-04-13 1995-04-11 Benzamide-derivate, zubereitungen die sie erhalten und ihre anwendung ATE218557T1 (de)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US08/227,033 US5387598A (en) 1994-04-13 1994-04-13 Composition and galenic formulation suitable for combatting affections of the lower abdomen
US08/301,407 US5578621A (en) 1994-09-08 1994-09-08 Benzamide derivatives
US38385595A 1995-02-06 1995-02-06
PCT/EP1995/001334 WO1995028393A1 (en) 1994-04-13 1995-04-11 Benzamide derivative, compositions containing said derivative and use thereof

Publications (1)

Publication Number Publication Date
ATE218557T1 true ATE218557T1 (de) 2002-06-15

Family

ID=27397680

Family Applications (1)

Application Number Title Priority Date Filing Date
AT95917310T ATE218557T1 (de) 1994-04-13 1995-04-11 Benzamide-derivate, zubereitungen die sie erhalten und ihre anwendung

Country Status (24)

Country Link
EP (1) EP0755386B1 (de)
JP (1) JP3224395B2 (de)
KR (2) KR100348440B1 (de)
CN (1) CN1072654C (de)
AP (1) AP645A (de)
AT (1) ATE218557T1 (de)
AU (1) AU689582B2 (de)
BG (1) BG62932B1 (de)
BR (1) BR9507371A (de)
CA (1) CA2187110C (de)
CZ (1) CZ287002B6 (de)
DE (1) DE69526936T2 (de)
DK (1) DK0755386T3 (de)
ES (1) ES2161201T3 (de)
FI (1) FI120258B (de)
HU (1) HUT77404A (de)
NZ (1) NZ284800A (de)
OA (1) OA10463A (de)
PL (1) PL186504B1 (de)
PT (1) PT755386E (de)
RU (1) RU2140915C1 (de)
SI (1) SI0755386T1 (de)
SK (1) SK281949B6 (de)
WO (1) WO1995028393A1 (de)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5968961A (en) 1997-05-07 1999-10-19 Romark Laboratories, L.C. Pharmaceutical compositions of tizoxanide and nitazoxanide
US5856348A (en) * 1994-09-08 1999-01-05 Romark Laboratories, L.C. Method for treatment of trematodes with pharmaceutical compositions of tizoxanide and nitazoxanide
CA2467321A1 (en) 2004-05-14 2005-11-14 Paul J. Santerre Polymeric coupling agents and pharmaceutically-active polymers made therefrom
DE602005023181D1 (de) 2004-07-21 2010-10-07 Dana Farber Cancer Inst Inc Lentivirusvektoren und deren verwendung
UA90864C2 (en) * 2004-09-09 2010-06-10 Ромарк Лебораториз, Л.К. Halogenated benzamide derivatives
WO2007081974A2 (en) 2006-01-09 2007-07-19 Romark Laboratories, L.C. Viral hepatitis treatment
US8124632B2 (en) 2007-08-03 2012-02-28 Romark Laboratories, L.C. Alkylsulfonyl-substituted thiazolide compounds
BRPI1010547A2 (pt) 2009-05-12 2019-04-09 Romark Laboratories L.C. composto, composição, e, métodos para tratar uma infecção viral, e rhabdovírus
PT2445349T (pt) 2009-06-26 2022-05-16 Romark Laboratories Lc Compostos e métodos para tratamento da gripe
AU2010310892B2 (en) 2009-10-22 2015-07-02 Thomas Julius Borody Novel parasite therapy
CN104094927B (zh) * 2013-04-02 2016-06-01 兴邦（武汉）生物科技有限公司 一种处理植物的助剂组合物
TW201630606A (zh) * 2015-01-21 2016-09-01 諾華公司 包含局部藥物之蓋崙（ｇａｌｅｎｉｃ）調配物
WO2019148293A1 (en) 2018-02-02 2019-08-08 Interface Biologics, Inc. Glass formulations comprising steroid dimers and uses thereof
US12473326B2 (en) 2019-02-01 2025-11-18 Ripple Therapeutics Corporation Crystalline forms of dexamethasone dimers and uses thereof
EP4010347A4 (de) 2019-08-07 2023-09-20 Ripple Therapeutics Corporation Zusammensetzungen und verfahren zur behandlung von schmerz und abhängigkeitserkrankungen
JP2023524494A (ja) 2020-05-01 2023-06-12 リップル セラピューティクス コーポレーション 眼障害を処置するためのヘテロ二量体組成物と方法
CA3219500A1 (en) * 2021-05-28 2022-12-01 Theodore HENDERSON Treatment using an antiviral compound and nitazoxanide

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1306603A (fr) * 1958-08-14 1962-10-19 Innothera Lab Sa Dérivés thiazoliques et leur procédé de préparation
FR716M (de) * 1960-08-05 1961-08-07
GB1437800A (en) * 1973-08-08 1976-06-03 Phavic Sprl Derivatives of 2-benzamido-5-nitro-thiazoles
GB1440212A (en) * 1973-08-29 1976-06-23 Phavic Sprl Derivatives of 2-phenoxyacetamido-5-nitrothiazoles
FR2435905A1 (fr) * 1978-09-13 1980-04-11 Anvar Nouveaux agents molluscicides derives du benzamido-2 nitro-5 thiazole
US4315018A (en) * 1978-12-07 1982-02-09 Rossignol Jean F Specific parasiticidal use of 2-benzamido-5-nitro-thiazole derivatives
US4447414A (en) * 1982-12-21 1984-05-08 Cutter Laboratories, Inc. Carnivore anthelmintics
US5387598A (en) * 1994-04-13 1995-02-07 Rossignol; Jean-Francois Composition and galenic formulation suitable for combatting affections of the lower abdomen

Also Published As

Publication number Publication date
FI964031A0 (fi) 1996-10-08
OA10463A (en) 2002-04-03
CN1072654C (zh) 2001-10-10
ES2161201T3 (es) 2002-12-01
PL316757A1 (en) 1997-02-03
JP3224395B2 (ja) 2001-10-29
CN1145621A (zh) 1997-03-19
AP9600866A0 (en) 1996-10-31
RU2140915C1 (ru) 1999-11-10
KR100348440B1 (ko) 2002-11-29
EP0755386A1 (de) 1997-01-29
SI0755386T1 (en) 2002-10-31
FI120258B (fi) 2009-08-31
EP0755386B1 (de) 2002-06-05
HUT77404A (hu) 1998-04-28
FI964031L (fi) 1996-10-08
SK281949B6 (sk) 2001-09-11
BR9507371A (pt) 1997-09-23
NZ284800A (en) 1998-02-26
PT755386E (pt) 2002-11-29
SK130796A3 (en) 1997-06-04
AU689582B2 (en) 1998-04-02
BG100884A (en) 1997-07-31
AU2344095A (en) 1995-11-10
HU9602798D0 (en) 1996-12-30
WO1995028393A1 (en) 1995-10-26
BG62932B1 (bg) 2000-11-30
DE69526936T2 (de) 2003-02-20
KR100373081B1 (ko) 2003-02-25
PL186504B1 (pl) 2004-01-30
CZ287002B6 (en) 2000-08-16
CA2187110C (en) 2002-03-19
DK0755386T3 (da) 2002-08-26
AP645A (en) 1998-04-24
ES2161201T1 (es) 2001-12-01
JPH09511997A (ja) 1997-12-02
CZ295996A3 (en) 1997-03-12
CA2187110A1 (en) 1995-10-26
DE69526936D1 (de) 2002-07-11

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
RZN Patent revoked
RZN Patent revoked