ATE337321T1 - Cabapenemderivate, ihre anwendung und ihre zwischenprodukte - Google Patents

Cabapenemderivate, ihre anwendung und ihre zwischenprodukte

Info

Publication number
ATE337321T1
ATE337321T1 AT99918272T AT99918272T ATE337321T1 AT E337321 T1 ATE337321 T1 AT E337321T1 AT 99918272 T AT99918272 T AT 99918272T AT 99918272 T AT99918272 T AT 99918272T AT E337321 T1 ATE337321 T1 AT E337321T1
Authority
AT
Austria
Prior art keywords
cabapenem
derivatives
intermediate products
products
cabapenem derivatives
Prior art date
Application number
AT99918272T
Other languages
English (en)
Inventor
Hiroshi Matsui
Original Assignee
Kyoto Pharma Ind
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP10122499A external-priority patent/JP2000344772A/ja
Priority claimed from JP10203730A external-priority patent/JP2000344773A/ja
Application filed by Kyoto Pharma Ind filed Critical Kyoto Pharma Ind
Application granted granted Critical
Publication of ATE337321T1 publication Critical patent/ATE337321T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D477/00—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring
    • C07D477/10—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • C07D477/12—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6
    • C07D477/16—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6 with hetero atoms or carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 3
    • C07D477/20—Sulfur atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
AT99918272T 1998-05-01 1999-04-28 Cabapenemderivate, ihre anwendung und ihre zwischenprodukte ATE337321T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP10122499A JP2000344772A (ja) 1998-05-01 1998-05-01 カルバペネム誘導体、その用途およびその中間体化合物
JP10203730A JP2000344773A (ja) 1998-07-17 1998-07-17 カルバペネム誘導体、およびその用途並びにその中間体化合物

Publications (1)

Publication Number Publication Date
ATE337321T1 true ATE337321T1 (de) 2006-09-15

Family

ID=26459604

Family Applications (1)

Application Number Title Priority Date Filing Date
AT99918272T ATE337321T1 (de) 1998-05-01 1999-04-28 Cabapenemderivate, ihre anwendung und ihre zwischenprodukte

Country Status (24)

Country Link
US (1) US6410525B1 (de)
EP (1) EP1078927B1 (de)
KR (1) KR100589030B1 (de)
CN (1) CN1163494C (de)
AR (1) AR018335A1 (de)
AT (1) ATE337321T1 (de)
AU (1) AU760386B2 (de)
BG (1) BG105004A (de)
BR (1) BR9910098A (de)
CA (1) CA2330641A1 (de)
CO (1) CO5011051A1 (de)
CZ (1) CZ292623B6 (de)
DE (1) DE69932927D1 (de)
HU (1) HUP0101735A3 (de)
ID (1) ID27081A (de)
NO (1) NO20005480L (de)
NZ (1) NZ508493A (de)
PL (1) PL343728A1 (de)
RU (1) RU2222540C2 (de)
SK (1) SK16382000A3 (de)
TR (1) TR200003199T2 (de)
TW (1) TW528750B (de)
WO (1) WO1999057121A1 (de)
YU (1) YU66700A (de)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1303485A1 (de) * 2000-07-19 2003-04-23 F. Hoffmann-La Roche Ag Pyrrolidin-derivate als endothelin konvertierende enzyminhibitoren
RU2289582C2 (ru) * 2001-05-21 2006-12-20 Киото Фармасьютикал Индастриз, Лтд. Соединение карбапенема
US7186855B2 (en) 2001-06-11 2007-03-06 Xenoport, Inc. Prodrugs of GABA analogs, compositions and uses thereof
US8048917B2 (en) 2005-04-06 2011-11-01 Xenoport, Inc. Prodrugs of GABA analogs, compositions and uses thereof
US6818787B2 (en) 2001-06-11 2004-11-16 Xenoport, Inc. Prodrugs of GABA analogs, compositions and uses thereof
CA2465336C (en) * 2001-11-05 2009-04-28 Sumitomo Pharmaceuticals Co., Ltd. Novel carbapenem compounds
WO2004089954A1 (ja) 2003-04-08 2004-10-21 Sumitomo Pharmaceuticals Co., Ltd. 新規なカルバペネム化合物
US20070265242A1 (en) * 2004-09-03 2007-11-15 Makoto Sunagawa Novel Carbapenem Compound
US20090029964A1 (en) * 2005-03-25 2009-01-29 Makoto Sunagawa Novel carbapenem compound
AU2006285043A1 (en) * 2005-08-31 2007-03-08 Wyeth 9-aminocarbonylsubstituted derivatives of glycylcyclines
CN101376656A (zh) * 2007-08-30 2009-03-04 山东轩竹医药科技有限公司 培南衍生物
US9725451B2 (en) 2013-03-15 2017-08-08 Kala Pharmaceuticals, Inc. Meropenem derivatives and uses thereof
CA3114618C (en) * 2018-10-01 2023-09-05 Arixa Pharmaceuticals, Inc. Derivatives of relebactam and uses thereof

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1283906C (en) 1983-05-09 1991-05-07 Makoto Sunagawa .beta.-LACTAM COMPOUNDS AND PRODUCTION THEREOF
JPS60233076A (ja) 1984-05-03 1985-11-19 Sumitomo Chem Co Ltd 新規なβ−ラクタム化合物およびその製造法
JPS61275279A (ja) 1984-12-25 1986-12-05 Sankyo Co Ltd カルバペネム化合物
IE60588B1 (en) 1986-07-30 1994-07-27 Sumitomo Pharma Carbapenem compound in crystalline form, and its production and use
DE68919508T2 (de) 1988-04-01 1995-07-20 Sankyo Co 2-(Heterocyclylthio)carbapenemderivate, deren Herstellung und deren Verwendung als Antibiotika.
US5242914A (en) 1988-04-01 1993-09-07 Sankyo Company, Limited 2-(heterocyclylthio) carbapenem derivatives, their preparation and their use as antibiotics
AU644008B2 (en) 1990-08-10 1993-12-02 Sumitomo Pharmaceuticals Company, Limited Beta-lactam compounds, and their production and use
US5712267A (en) 1991-06-04 1998-01-27 Sankyo Company,. Limited Carbapenem derivatives, their preparation and their use as antibiotics
US5360798A (en) 1991-07-04 1994-11-01 Shionogi Seiyaku Kabushiki Kaisha Aminooxypyrrolidinylthiocarbapenem compounds
DE69623497T2 (de) 1995-12-21 2003-05-28 Sankyo Co 1-methylcarbapenem-derivate

Also Published As

Publication number Publication date
CO5011051A1 (es) 2001-02-28
KR20010043196A (ko) 2001-05-25
WO1999057121A1 (fr) 1999-11-11
AU760386B2 (en) 2003-05-15
CN1307578A (zh) 2001-08-08
CN1163494C (zh) 2004-08-25
KR100589030B1 (ko) 2006-06-13
EP1078927A4 (de) 2003-01-08
EP1078927A1 (de) 2001-02-28
CA2330641A1 (en) 1999-11-11
AU3627299A (en) 1999-11-23
EP1078927B1 (de) 2006-08-23
HUP0101735A2 (hu) 2001-12-28
NO20005480L (no) 2000-12-20
BR9910098A (pt) 2000-12-26
NZ508493A (en) 2002-06-28
ID27081A (id) 2001-02-22
DE69932927D1 (de) 2006-10-05
CZ292623B6 (cs) 2003-11-12
HUP0101735A3 (en) 2002-02-28
BG105004A (en) 2001-08-31
SK16382000A3 (sk) 2001-05-10
YU66700A (sh) 2003-01-31
CZ20003954A3 (cs) 2001-04-11
RU2222540C2 (ru) 2004-01-27
TW528750B (en) 2003-04-21
TR200003199T2 (tr) 2001-03-21
PL343728A1 (en) 2001-09-10
US6410525B1 (en) 2002-06-25
AR018335A1 (es) 2001-11-14
NO20005480D0 (no) 2000-10-31

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Legal Events

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RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties