ZA952410B - Substituted heterocyclic carboxamioesters their preparation and their use as pharmaceuticals - Google Patents
Substituted heterocyclic carboxamioesters their preparation and their use as pharmaceuticalsInfo
- Publication number
- ZA952410B ZA952410B ZA952410A ZA952410A ZA952410B ZA 952410 B ZA952410 B ZA 952410B ZA 952410 A ZA952410 A ZA 952410A ZA 952410 A ZA952410 A ZA 952410A ZA 952410 B ZA952410 B ZA 952410B
- Authority
- ZA
- South Africa
- Prior art keywords
- carboxamioesters
- pharmaceuticals
- preparation
- substituted heterocyclic
- heterocyclic
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/81—Amides; Imides
- C07D213/82—Amides; Imides in position 3
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/89—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members with hetero atoms directly attached to the ring nitrogen atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyridine Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE4410453A DE4410453A1 (en) | 1994-03-25 | 1994-03-25 | Substituted heterocyclic carboxylic acid amide esters, their preparation and their use as medicaments |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA952410B true ZA952410B (en) | 1995-12-01 |
Family
ID=6513880
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA952410A ZA952410B (en) | 1994-03-25 | 1995-03-24 | Substituted heterocyclic carboxamioesters their preparation and their use as pharmaceuticals |
Country Status (12)
| Country | Link |
|---|---|
| EP (1) | EP0673930A1 (en) |
| JP (1) | JPH07278111A (en) |
| KR (1) | KR950032127A (en) |
| AU (1) | AU1504495A (en) |
| CA (1) | CA2145473A1 (en) |
| CZ (1) | CZ73595A3 (en) |
| DE (1) | DE4410453A1 (en) |
| FI (1) | FI951388A (en) |
| HU (1) | HUT72596A (en) |
| NO (1) | NO951147L (en) |
| PL (1) | PL307846A1 (en) |
| ZA (1) | ZA952410B (en) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0206711D0 (en) | 2002-03-21 | 2002-05-01 | Isis Innovation | HIF Inhibitor |
| US7915443B2 (en) * | 2006-11-16 | 2011-03-29 | Allergan, Inc. | Sulfoximines as kinase inhibitors |
| US8558002B2 (en) | 2006-11-16 | 2013-10-15 | Allergan, Inc. | Sulfoximines as kinase inhibitors |
| TWI735416B (en) | 2014-10-06 | 2021-08-11 | 美商維泰克斯製藥公司 | Modulators of cystic fibrosis transmembrane conductance regulator |
| PL3436446T3 (en) | 2016-03-31 | 2023-09-11 | Vertex Pharmaceuticals Incorporated | Modulators of cystic fibrosis transmembrane conductance regulator |
| CN109803962B (en) | 2016-09-30 | 2022-04-29 | 弗特克斯药品有限公司 | Modulators of cystic fibrosis transmembrane conductance regulator proteins, and pharmaceutical compositions |
| MA54847A (en) | 2016-12-09 | 2021-12-08 | Vertex Pharma | CRYSTALLINE FORM OF AN N-(PYRAZOL-4-YL)SULFONYL-6-(PYRAZOL-1-YL)-2-(PYRROLIDIN-1-YL)PYRIDINE-3-CARBOXAMIDE FOR TREATING VUD |
| EP3634402A1 (en) | 2017-06-08 | 2020-04-15 | Vertex Pharmaceuticals Incorporated | Methods of treatment for cystic fibrosis |
| WO2019018395A1 (en) | 2017-07-17 | 2019-01-24 | Vertex Pharmaceuticals Incorporated | Methods of treatment for cystic fibrosis |
| ES2912657T3 (en) | 2017-08-02 | 2022-05-26 | Vertex Pharma | Processes for preparing pyrrolidine compounds |
| AU2018351533B2 (en) | 2017-10-19 | 2023-02-02 | Vertex Pharmaceuticals Incorporated | Crystalline forms and compositions of CFTR modulators |
| KR20200097293A (en) | 2017-12-08 | 2020-08-18 | 버텍스 파마슈티칼스 인코포레이티드 | Method for producing a modulator of cystic fibrosis transmembrane conduction modulator |
| TWI810243B (en) | 2018-02-05 | 2023-08-01 | 美商維泰克斯製藥公司 | Pharmaceutical compositions for treating cystic fibrosis |
| US11414439B2 (en) | 2018-04-13 | 2022-08-16 | Vertex Pharmaceuticals Incorporated | Modulators of cystic fibrosis transmembrane conductance regulator, pharmaceutical compositions, methods of treatment, and process for making the modulator |
| US11806405B1 (en) | 2021-07-19 | 2023-11-07 | Zeno Management, Inc. | Immunoconjugates and methods |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TW352384B (en) * | 1992-03-24 | 1999-02-11 | Hoechst Ag | Sulfonamido- or sulfonamidocarbonylpyridine-2-carboxamides, process for their preparation and their use as pharmaceuticals |
-
1994
- 1994-03-25 DE DE4410453A patent/DE4410453A1/en not_active Withdrawn
-
1995
- 1995-03-09 EP EP95103405A patent/EP0673930A1/en not_active Withdrawn
- 1995-03-23 FI FI951388A patent/FI951388A/en unknown
- 1995-03-23 CZ CZ95735A patent/CZ73595A3/en unknown
- 1995-03-23 AU AU15044/95A patent/AU1504495A/en not_active Abandoned
- 1995-03-24 ZA ZA952410A patent/ZA952410B/en unknown
- 1995-03-24 NO NO951147A patent/NO951147L/en unknown
- 1995-03-24 JP JP7065927A patent/JPH07278111A/en active Pending
- 1995-03-24 CA CA002145473A patent/CA2145473A1/en not_active Abandoned
- 1995-03-24 PL PL95307846A patent/PL307846A1/en unknown
- 1995-03-24 HU HU9500863A patent/HUT72596A/en unknown
- 1995-03-25 KR KR1019950006806A patent/KR950032127A/en not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| NO951147L (en) | 1995-09-26 |
| NO951147D0 (en) | 1995-03-24 |
| CA2145473A1 (en) | 1995-09-26 |
| HUT72596A (en) | 1996-05-28 |
| EP0673930A1 (en) | 1995-09-27 |
| DE4410453A1 (en) | 1995-09-28 |
| KR950032127A (en) | 1995-12-20 |
| FI951388A0 (en) | 1995-03-23 |
| FI951388A (en) | 1995-09-26 |
| CZ73595A3 (en) | 1995-11-15 |
| JPH07278111A (en) | 1995-10-24 |
| PL307846A1 (en) | 1995-10-02 |
| AU1504495A (en) | 1995-10-05 |
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