FI951388A0 - Substituted heterocyclic carboxylic acid amide esters, their preparation and their use as medicaments - Google Patents

Substituted heterocyclic carboxylic acid amide esters, their preparation and their use as medicaments

Info

Publication number
FI951388A0
FI951388A0 FI951388A FI951388A FI951388A0 FI 951388 A0 FI951388 A0 FI 951388A0 FI 951388 A FI951388 A FI 951388A FI 951388 A FI951388 A FI 951388A FI 951388 A0 FI951388 A0 FI 951388A0
Authority
FI
Finland
Prior art keywords
medicaments
preparation
carboxylic acid
acid amide
substituted heterocyclic
Prior art date
Application number
FI951388A
Other languages
Finnish (fi)
Swedish (sv)
Other versions
FI951388A (en
Inventor
Klaus Weidmann
Karl-Heinz Baringhaus
Georg Tschank
Martin Bickel
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of FI951388A0 publication Critical patent/FI951388A0/en
Publication of FI951388A publication Critical patent/FI951388A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/89—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members with hetero atoms directly attached to the ring nitrogen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/81—Amides; Imides
    • C07D213/82—Amides; Imides in position 3
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
FI951388A 1994-03-25 1995-03-23 Substituted heterocyclic carboxylic acid amide esters, their preparation and their use as medicaments FI951388A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4410453A DE4410453A1 (en) 1994-03-25 1994-03-25 Substituted heterocyclic carboxylic acid amide esters, their preparation and their use as medicaments

Publications (2)

Publication Number Publication Date
FI951388A0 true FI951388A0 (en) 1995-03-23
FI951388A FI951388A (en) 1995-09-26

Family

ID=6513880

Family Applications (1)

Application Number Title Priority Date Filing Date
FI951388A FI951388A (en) 1994-03-25 1995-03-23 Substituted heterocyclic carboxylic acid amide esters, their preparation and their use as medicaments

Country Status (12)

Country Link
EP (1) EP0673930A1 (en)
JP (1) JPH07278111A (en)
KR (1) KR950032127A (en)
AU (1) AU1504495A (en)
CA (1) CA2145473A1 (en)
CZ (1) CZ73595A3 (en)
DE (1) DE4410453A1 (en)
FI (1) FI951388A (en)
HU (1) HUT72596A (en)
NO (1) NO951147L (en)
PL (1) PL307846A1 (en)
ZA (1) ZA952410B (en)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0206711D0 (en) * 2002-03-21 2002-05-01 Isis Innovation HIF Inhibitor
JP2010510242A (en) * 2006-11-16 2010-04-02 アラーガン、インコーポレイテッド Sulfoximine as a kinase inhibitor
US8558002B2 (en) 2006-11-16 2013-10-15 Allergan, Inc. Sulfoximines as kinase inhibitors
MA41051B1 (en) 2014-10-06 2020-11-30 Vertex Pharma Modulators of the transmembrane conductance regulator of cystic fibrosis
ES2946970T3 (en) 2016-03-31 2023-07-28 Vertex Pharma Transmembrane conductance regulator of cystic fibrosis modulators
RS62670B1 (en) 2016-09-30 2021-12-31 Vertex Pharma Modulator of cystic fibrosis transmembrane conductance regulator, pharmaceutical compositions, methods of treatment, and process for making the modulator
JOP20190125B1 (en) 2016-12-09 2022-03-14 Vertex Pharma Modulator of Cystic Fibrosis Transmembrane Conductance Regulator, Pharmaceutical Compositions, Methods of Treatment, and Process for Making the Modulator
US11253509B2 (en) 2017-06-08 2022-02-22 Vertex Pharmaceuticals Incorporated Methods of treatment for cystic fibrosis
MA49631A (en) 2017-07-17 2020-05-27 Vertex Pharma CYSTIC FIBROSIS TREATMENT METHODS
KR102606188B1 (en) 2017-08-02 2023-11-23 버텍스 파마슈티칼스 인코포레이티드 Process for producing pyrrolidine compounds
CA3078893A1 (en) 2017-10-19 2019-04-25 Vertex Pharmaceuticals Incorporated Crystalline forms and compositions of cftr modulators
MX2020005753A (en) 2017-12-08 2020-08-20 Vertex Pharma Processes for making modulators of cystic fibrosis transmembrane conductance regulator.
TWI810243B (en) 2018-02-05 2023-08-01 美商維泰克斯製藥公司 Pharmaceutical compositions for treating cystic fibrosis
WO2019200246A1 (en) 2018-04-13 2019-10-17 Alexander Russell Abela Modulators of cystic fibrosis transmembrane conductance regulator, pharmaceutical compositions, methods of treatment, and process for making the modulator
US11806405B1 (en) 2021-07-19 2023-11-07 Zeno Management, Inc. Immunoconjugates and methods

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW352384B (en) * 1992-03-24 1999-02-11 Hoechst Ag Sulfonamido- or sulfonamidocarbonylpyridine-2-carboxamides, process for their preparation and their use as pharmaceuticals

Also Published As

Publication number Publication date
CA2145473A1 (en) 1995-09-26
CZ73595A3 (en) 1995-11-15
PL307846A1 (en) 1995-10-02
FI951388A (en) 1995-09-26
AU1504495A (en) 1995-10-05
ZA952410B (en) 1995-12-01
HUT72596A (en) 1996-05-28
EP0673930A1 (en) 1995-09-27
NO951147D0 (en) 1995-03-24
KR950032127A (en) 1995-12-20
JPH07278111A (en) 1995-10-24
NO951147L (en) 1995-09-26
DE4410453A1 (en) 1995-09-28

Similar Documents

Publication Publication Date Title
HUP9903405A3 (en) Cyclic and heterocyclic n-substituted alpha-iminohydroxamic and carboxylic acids with metalloproteinase inhibitor activity, preparation and use thereof
DE59706602D1 (en) 3-Hydroxy-pyridine-2-carboxylic acid amide esters, their preparation and their use as medicaments
IL110821A0 (en) Carbocyclic and heterocyclic fused-ring quinolinecarboxylic acids and pharmaceutical compositions comprising them
NO924978L (en) CHINOLON AND NAFTYRIDON CARBOXYLIC ACID DERIVATIVES
FI940874A0 (en) Process for the preparation of lactic acid and lactic acid esters
FI951388A (en) Substituted heterocyclic carboxylic acid amide esters, their preparation and their use as medicaments
EE9500059A (en) Use of substituted 4-phenyl-6-aminonicotinic acid derivatives as medicaments
EE03767B1 (en) Arylglycine amide derivatives, process for their preparation and use, and pharmaceutical preparation
FI954255A0 (en) 2,9-Diamino- and 2-amino-8-carbaomyl-4-hydroxy-alkanoic acid amide derivatives
EE9900034A (en) Arylcycloalkanecarboxylic esters, their use, pharmaceutical compositions and their preparation
DK0673647T3 (en) Dermatological composition containing lactic acid salt
FI951726A (en) Boronic acid peptide derivatives, their preparation and use as synthetic intermediates
FI960634A (en) New quinolone carboxylic acid derivatives
HUP0000084A3 (en) 3-alkoxyisoxazol-4-yl-substituted-2-amino carboxylic acid derivatives, their use and pharmaceutical compositions containing them
FI951385A0 (en) Substituted heterocyclic carboxylic acid amides, their preparation and their use as medicaments
EE9500055A (en) Use of 1,4-dihydropyridine-3,5-dicarboxylic acid esters as medicaments, medicaments and their method of preparation
FI951725A (en) Aminoboronic acid derivatives, their preparation and use as synthetic intermediates
DE69419180T2 (en) Nicotinic acid derivatives and herbicides
HUP0100957A3 (en) 5-substituted pyrimidine-2-yloxy carboxylic acid derivatives, the production of the same, their use and pharmaceutical compositions containing them
NO960777D0 (en) Use of N-alkylated 1,4-dihydropyridine dicarboxylic acid esters as medicaments
EE200200267A (en) Substituted 1,2,3,4,5,6-hexahydro-2,6-methano-3-benzazocines and their use as medicaments
FI941082A0 (en) Quinolone carboxylic acid derivatives, their preparation and use
NO923114L (en) HETEROCYCLIC CARBOXYLIC ACID ESTERS, PROCEDURES FOR THE PREPARATION OF THEM, AND THE USE OF THEM FOR THE PREPARATION OF AVGASTRO-INTESTINAL MEDICINES
FI971012A (en) 1,4-Dihydro-4-oxo-3-quinolinecarboxylic acid derivatives and their use
ZA948579B (en) Substituted heterocyclic carboxamide esters,their preparation and their use as pharmaceuticals