DE69413395D1 - Nicht oxydierendes, medizinisches polymerimplantat - Google Patents

Nicht oxydierendes, medizinisches polymerimplantat

Info

Publication number
DE69413395D1
DE69413395D1 DE69413395T DE69413395T DE69413395D1 DE 69413395 D1 DE69413395 D1 DE 69413395D1 DE 69413395 T DE69413395 T DE 69413395T DE 69413395 T DE69413395 T DE 69413395T DE 69413395 D1 DE69413395 D1 DE 69413395D1
Authority
DE
Germany
Prior art keywords
molecular weight
polyethylene
medical implant
average molecular
high molecular
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69413395T
Other languages
English (en)
Other versions
DE69413395T2 (de
Inventor
Deh-Chuan Sun
Casper Stark
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Howmedica Osteonics Corp
Original Assignee
Howmedica Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22092961&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE69413395(D1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Howmedica Inc filed Critical Howmedica Inc
Publication of DE69413395D1 publication Critical patent/DE69413395D1/de
Application granted granted Critical
Publication of DE69413395T2 publication Critical patent/DE69413395T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
    • A61L2/02Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor using physical phenomena
    • A61L2/08Radiation
    • A61L2/081Gamma radiation
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/42Use of materials characterised by their function or physical properties
    • A61L15/60Liquid-swellable gel-forming materials, e.g. super-absorbents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
    • A61L2/02Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor using physical phenomena
    • A61L2/08Radiation
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
    • A61L2/02Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor using physical phenomena
    • A61L2/08Radiation
    • A61L2/082X-rays
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
    • A61L2/02Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor using physical phenomena
    • A61L2/08Radiation
    • A61L2/087Particle radiation, e.g. electron-beam, alpha or beta radiation
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14Macromolecular materials
    • A61L27/16Macromolecular materials obtained by reactions only involving carbon-to-carbon unsaturated bonds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L29/00Materials for catheters, medical tubing, cannulae, or endoscopes or for coating catheters
    • A61L29/04Macromolecular materials
    • A61L29/041Macromolecular materials obtained by reactions only involving carbon-to-carbon unsaturated bonds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/04Macromolecular materials
    • A61L31/048Macromolecular materials obtained by reactions only involving carbon-to-carbon unsaturated bonds
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B29WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29CSHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C35/00Heating, cooling or curing, e.g. crosslinking or vulcanising; Apparatus therefor
    • B29C35/02Heating or curing, e.g. crosslinking or vulcanizing during moulding, e.g. in a mould
    • B29C35/08Heating or curing, e.g. crosslinking or vulcanizing during moulding, e.g. in a mould by wave energy or particle radiation
    • B29C35/0805Heating or curing, e.g. crosslinking or vulcanizing during moulding, e.g. in a mould by wave energy or particle radiation using electromagnetic radiation
    • B29C2035/085Heating or curing, e.g. crosslinking or vulcanizing during moulding, e.g. in a mould by wave energy or particle radiation using electromagnetic radiation using gamma-ray
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B29WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29CSHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C35/00Heating, cooling or curing, e.g. crosslinking or vulcanising; Apparatus therefor
    • B29C35/02Heating or curing, e.g. crosslinking or vulcanizing during moulding, e.g. in a mould
    • B29C35/08Heating or curing, e.g. crosslinking or vulcanizing during moulding, e.g. in a mould by wave energy or particle radiation
    • B29C35/0805Heating or curing, e.g. crosslinking or vulcanizing during moulding, e.g. in a mould by wave energy or particle radiation using electromagnetic radiation
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B29WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29CSHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C43/00Compression moulding, i.e. applying external pressure to flow the moulding material; Apparatus therefor
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B29WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29CSHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C43/00Compression moulding, i.e. applying external pressure to flow the moulding material; Apparatus therefor
    • B29C43/02Compression moulding, i.e. applying external pressure to flow the moulding material; Apparatus therefor of articles of definite length, i.e. discrete articles
    • B29C43/16Forging
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B29WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29KINDEXING SCHEME ASSOCIATED WITH SUBCLASSES B29B, B29C OR B29D, RELATING TO MOULDING MATERIALS OR TO MATERIALS FOR MOULDS, REINFORCEMENTS, FILLERS OR PREFORMED PARTS, e.g. INSERTS
    • B29K2023/00Use of polyalkenes or derivatives thereof as moulding material
    • B29K2023/04Polymers of ethylene
    • B29K2023/06PE, i.e. polyethylene
    • B29K2023/0658PE, i.e. polyethylene characterised by its molecular weight
    • B29K2023/0683UHMWPE, i.e. ultra high molecular weight polyethylene
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B29WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29KINDEXING SCHEME ASSOCIATED WITH SUBCLASSES B29B, B29C OR B29D, RELATING TO MOULDING MATERIALS OR TO MATERIALS FOR MOULDS, REINFORCEMENTS, FILLERS OR PREFORMED PARTS, e.g. INSERTS
    • B29K2105/00Condition, form or state of moulded material or of the material to be shaped
    • B29K2105/25Solid
    • B29K2105/253Preform
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B29WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29KINDEXING SCHEME ASSOCIATED WITH SUBCLASSES B29B, B29C OR B29D, RELATING TO MOULDING MATERIALS OR TO MATERIALS FOR MOULDS, REINFORCEMENTS, FILLERS OR PREFORMED PARTS, e.g. INSERTS
    • B29K2995/00Properties of moulding materials, reinforcements, fillers, preformed parts or moulds
    • B29K2995/0037Other properties
    • B29K2995/0087Wear resistance
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B29WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29KINDEXING SCHEME ASSOCIATED WITH SUBCLASSES B29B, B29C OR B29D, RELATING TO MOULDING MATERIALS OR TO MATERIALS FOR MOULDS, REINFORCEMENTS, FILLERS OR PREFORMED PARTS, e.g. INSERTS
    • B29K2995/00Properties of moulding materials, reinforcements, fillers, preformed parts or moulds
    • B29K2995/0037Other properties
    • B29K2995/0089Impact strength or toughness
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B29WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29LINDEXING SCHEME ASSOCIATED WITH SUBCLASS B29C, RELATING TO PARTICULAR ARTICLES
    • B29L2031/00Other particular articles
    • B29L2031/753Medical equipment; Accessories therefor
    • B29L2031/7532Artificial members, protheses
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S522/00Synthetic resins or natural rubbers -- part of the class 520 series
    • Y10S522/915Synthetic resins or natural rubbers -- part of the class 520 series involving inert gas, steam, nitrogen gas, or carbon dioxide
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S525/00Synthetic resins or natural rubbers -- part of the class 520 series
    • Y10S525/937Utility as body contact e.g. implant, contact lens or I.U.D.
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S623/00Prosthesis, i.e. artificial body members, parts thereof, or aids and accessories therefor
    • Y10S623/901Method of manufacturing prosthetic device
DE69413395T 1993-06-01 1994-04-26 Nicht oxydierendes, medizinisches polymerimplantat Expired - Lifetime DE69413395T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/070,074 US5414049A (en) 1993-06-01 1993-06-01 Non-oxidizing polymeric medical implant
PCT/IB1994/000083 WO1994027651A1 (en) 1993-06-01 1994-04-26 Non-oxidizing polymeric medical implant

Publications (2)

Publication Number Publication Date
DE69413395D1 true DE69413395D1 (de) 1998-10-22
DE69413395T2 DE69413395T2 (de) 1999-02-04

Family

ID=22092961

Family Applications (4)

Application Number Title Priority Date Filing Date
DE69425838T Expired - Lifetime DE69425838T2 (de) 1993-06-01 1994-04-26 Nicht-oxydierendes, medizinisches Polymerimplantat
DE69434462T Expired - Lifetime DE69434462T2 (de) 1993-06-01 1994-04-26 Nicht-oxydierendes, medizinisches Polymerimplantat
DE69413395T Expired - Lifetime DE69413395T2 (de) 1993-06-01 1994-04-26 Nicht oxydierendes, medizinisches polymerimplantat
DE9490446U Expired - Lifetime DE9490446U1 (de) 1993-06-01 1994-04-26 Nichtoxidierendes polymeres medizinisches Implantat

Family Applications Before (2)

Application Number Title Priority Date Filing Date
DE69425838T Expired - Lifetime DE69425838T2 (de) 1993-06-01 1994-04-26 Nicht-oxydierendes, medizinisches Polymerimplantat
DE69434462T Expired - Lifetime DE69434462T2 (de) 1993-06-01 1994-04-26 Nicht-oxydierendes, medizinisches Polymerimplantat

Family Applications After (1)

Application Number Title Priority Date Filing Date
DE9490446U Expired - Lifetime DE9490446U1 (de) 1993-06-01 1994-04-26 Nichtoxidierendes polymeres medizinisches Implantat

Country Status (9)

Country Link
US (10) US5414049A (de)
EP (4) EP1005872B1 (de)
JP (1) JP2836965B2 (de)
AT (3) ATE196095T1 (de)
AU (1) AU684500B2 (de)
CA (1) CA2162927C (de)
DE (4) DE69425838T2 (de)
ES (1) ES2122260T3 (de)
WO (1) WO1994027651A1 (de)

Families Citing this family (215)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5830396A (en) * 1993-01-21 1998-11-03 Biomet, Inc. Method for processing thermoplastics, thermosets and elastomers
US5505984A (en) * 1993-01-21 1996-04-09 England; Garry L. Method for forming biocompatible components using an isostatic press
US5414049A (en) * 1993-06-01 1995-05-09 Howmedica Inc. Non-oxidizing polymeric medical implant
US6800095B1 (en) 1994-08-12 2004-10-05 Diamicron, Inc. Diamond-surfaced femoral head for use in a prosthetic joint
US7077867B1 (en) 1994-08-12 2006-07-18 Diamicron, Inc. Prosthetic knee joint having at least one diamond articulation surface
US7494507B2 (en) * 2000-01-30 2009-02-24 Diamicron, Inc. Articulating diamond-surfaced spinal implants
US6494918B1 (en) 2000-01-30 2002-12-17 Diamicron, Inc. Component for a prosthetic joint having a diamond load bearing and articulation surface
US6517583B1 (en) 2000-01-30 2003-02-11 Diamicron, Inc. Prosthetic hip joint having a polycrystalline diamond compact articulation surface and a counter bearing surface
US7678325B2 (en) * 1999-12-08 2010-03-16 Diamicron, Inc. Use of a metal and Sn as a solvent material for the bulk crystallization and sintering of diamond to produce biocompatbile biomedical devices
US6596225B1 (en) 2000-01-31 2003-07-22 Diamicron, Inc. Methods for manufacturing a diamond prosthetic joint component
US6514289B1 (en) 2000-01-30 2003-02-04 Diamicron, Inc. Diamond articulation surface for use in a prosthetic joint
US6290726B1 (en) 2000-01-30 2001-09-18 Diamicron, Inc. Prosthetic hip joint having sintered polycrystalline diamond compact articulation surfaces
US6425922B1 (en) 2000-01-30 2002-07-30 Diamicron, Inc. Prosthetic hip joint having at least one sintered polycrystalline diamond compact articulation surface
EP0729981B1 (de) 1994-09-21 2002-03-20 Bmg Incorporated Polyethylenguss mit ultrahohem molekulargewicht für künstliche verbindungen und verfahren zu dessen herstellung
JP3380642B2 (ja) * 1995-01-18 2003-02-24 本田技研工業株式会社 車両の駆動力演算装置
CA2166450C (en) * 1995-01-20 2008-03-25 Ronald Salovey Chemically crosslinked ultrahigh molecular weight polyethylene for artificial human joints
US5577368A (en) * 1995-04-03 1996-11-26 Johnson & Johnson Professional, Inc. Method for improving wear resistance of polymeric bioimplantable components
US5674290A (en) * 1995-04-05 1997-10-07 Li; Shu-Tung Water-stabilized biopolymeric implants
JP5073626B2 (ja) * 1996-02-13 2012-11-14 マサチューセッツ インスティテュート オブ テクノロジー 放射線および溶融処理済み超高分子量ポリエチレンプロテーゼデバイス
US20020156536A1 (en) * 1996-02-13 2002-10-24 Harris William H. Polyethylene hip joint prosthesis with extended range of motion
US5879400A (en) * 1996-02-13 1999-03-09 Massachusetts Institute Of Technology Melt-irradiated ultra high molecular weight polyethylene prosthetic devices
PL189246B1 (pl) * 1996-02-13 2005-07-29 Gen Hospital Corp Sposób otrzymywania usieciowanego polietylenu o ultrawysokim ciężarze cząsteczkowym, medyczna proteza do stosowania wewnątrz ciała oraz zastosowanie poddanego działaniu promieniowania polietylenu o ultrawysokim ciężarze cząsteczkowym
US8563623B2 (en) * 1996-02-13 2013-10-22 The General Hospital Corporation Radiation melt treated ultra high molecular weight polyethylene prosthetic devices
US8865788B2 (en) * 1996-02-13 2014-10-21 The General Hospital Corporation Radiation and melt treated ultra high molecular weight polyethylene prosthetic devices
US5753182A (en) * 1996-02-14 1998-05-19 Biomet, Inc. Method for reducing the number of free radicals present in ultrahigh molecular weight polyethylene orthopedic components
US5598937A (en) * 1996-02-14 1997-02-04 Keystone Industries, Inc. Slackless drawbar assembly
US6228900B1 (en) 1996-07-09 2001-05-08 The Orthopaedic Hospital And University Of Southern California Crosslinking of polyethylene for low wear using radiation and thermal treatments
JP2000514481A (ja) * 1996-07-09 2000-10-31 ザ オーソピーディック ホスピタル 放射線及び熱処理を用いた低摩耗ポリエチレンの架橋
US6017975A (en) 1996-10-02 2000-01-25 Saum; Kenneth Ashley Process for medical implant of cross-linked ultrahigh molecular weight polyethylene having improved balance of wear properties and oxidation resistance
EP1028760B1 (de) * 1996-10-15 2004-04-14 Orthopaedic Hospital Verschleissfestes vernetztes polyethylen mit oberflächengradienten
IT1298376B1 (it) * 1997-12-16 2000-01-05 Samo Spa Trattamento di reticolazione e sterilizzazione per la produzione di manufatti in polietilene ad elevate caratteristiche tribologiche,
EP0963824B1 (de) * 1998-06-10 2004-12-08 DePuy Products, Inc. Verfahren zur Herstellung vernetzter, geformter Kunststofflager
EP1413414B1 (de) * 1998-06-10 2006-12-13 Depuy Products, Inc. Verfahren zur Herstellung vernetzter geformter Kunststofflager
US6692679B1 (en) * 1998-06-10 2004-02-17 Depuy Orthopaedics, Inc. Cross-linked molded plastic bearings
US5997969A (en) * 1998-08-27 1999-12-07 Gardon; John L. Non-allergenic medical and health care devices made from crosslinked synthetic elastomers
EP0995450B1 (de) * 1998-10-21 2002-06-26 Sulzer Orthopädie AG UHMW-Polyethylen für Implantate
EP0995449A1 (de) * 1998-10-21 2000-04-26 Sulzer Orthopädie AG UHMW-Polyethylen für Implantate
US6986868B2 (en) * 1998-11-20 2006-01-17 Coloplast A/S Method for sterilizing a medical device having a hydrophilic coating
EP2065061B1 (de) 1998-11-20 2015-03-25 Coloplast A/S Verfahren zum Schutz von hydrophilen Beschichtungen von Kathetern während der Strahlensterilisation
ATE274765T1 (de) * 1999-01-22 2004-09-15 Multigig Ltd Elektronische schaltungsanordnung
US6355215B1 (en) 1999-03-10 2002-03-12 Implex Corp. Wear-resistant olefinic medical implant and thermal treatment container therefor
US6203844B1 (en) * 1999-04-01 2001-03-20 Joon B. Park Precoated polymeric prosthesis and process for making same
JP2002541916A (ja) 1999-04-21 2002-12-10 ハウメディカ・アスティオニクス・コーポレイション 選択架橋ポリエチレン整形装置
US6239197B1 (en) * 1999-04-23 2001-05-29 Great Lakes Chemical Corporation Vacuum de-aerated powdered polymer additives
US6627141B2 (en) 1999-06-08 2003-09-30 Depuy Orthopaedics, Inc. Method for molding a cross-linked preform
US6245276B1 (en) 1999-06-08 2001-06-12 Depuy Orthopaedics, Inc. Method for molding a cross-linked preform
US6432349B1 (en) 1999-06-29 2002-08-13 Zimmer, Inc. Process of making an articulating bearing surface
US6184265B1 (en) * 1999-07-29 2001-02-06 Depuy Orthopaedics, Inc. Low temperature pressure stabilization of implant component
US6143232A (en) * 1999-07-29 2000-11-07 Bristol-Meyers Squibb Company Method of manufacturing an articulating bearing surface for an orthopaedic implant
AU4890400A (en) * 1999-07-29 2001-02-01 Depuy Orthopaedics, Inc. Two step gamma irradiation of polymeric bioimplant
EP1072277A1 (de) * 1999-07-29 2001-01-31 Depuy Orthopaedics, Inc. Hitzebehandlung von gamma-bestrahlten Implantaten zur Erhöhung der mechanischen Stabilität
US6794423B1 (en) * 1999-07-30 2004-09-21 Stephen Li Fracture-resistant, cross-linked ultra high molecular weight polyethylene shaped material and articles made therefrom
US6365089B1 (en) 1999-09-24 2002-04-02 Zimmer, Inc. Method for crosslinking UHMWPE in an orthopaedic implant
US7569176B2 (en) * 1999-12-08 2009-08-04 Diamicron, Inc. Method for making a sintered superhard prosthetic joint component
US7556763B2 (en) * 1999-12-08 2009-07-07 Diamicron, Inc. Method of making components for prosthetic joints
US20040199260A1 (en) * 2000-01-30 2004-10-07 Pope Bill J. Prosthetic joint component having at least one sintered polycrystalline diamond compact articulation surface and substrate surface topographical features in said polycrystalline diamond compact
US6709463B1 (en) 2000-01-30 2004-03-23 Diamicron, Inc. Prosthetic joint component having at least one solid polycrystalline diamond component
US8603181B2 (en) * 2000-01-30 2013-12-10 Dimicron, Inc Use of Ti and Nb cemented in TiC in prosthetic joints
US20100025898A1 (en) * 2000-01-30 2010-02-04 Pope Bill J USE OF Ti AND Nb CEMENTED TiC IN PROSTHETIC JOINTS
US6410877B1 (en) 2000-01-30 2002-06-25 Diamicron, Inc. Methods for shaping and finishing prosthetic joint components including polycrystalline diamond compacts
US20050203630A1 (en) * 2000-01-30 2005-09-15 Pope Bill J. Prosthetic knee joint having at least one diamond articulation surface
US6395799B1 (en) 2000-02-21 2002-05-28 Smith & Nephew, Inc. Electromagnetic and mechanical wave energy treatments of UHMWPE
US6414086B1 (en) 2000-02-29 2002-07-02 Howmedica Osteonics Corp. Compositions, processes and methods of improving the wear resistance of prosthetic medical devices
US6626945B2 (en) 2000-03-14 2003-09-30 Chondrosite, Llc Cartilage repair plug
US6632246B1 (en) 2000-03-14 2003-10-14 Chondrosite, Llc Cartilage repair plug
AU6108301A (en) * 2000-04-27 2001-11-07 Orthopaedic Hospital Oxidation-resistant and wear-resistant polyethylenes for human joint replacements and methods for making them
JP4354181B2 (ja) * 2000-07-31 2009-10-28 ザ・ジェネラル・ホスピタル・コーポレイション 転位の危険性を減少させる改良された寛骨臼コンポーネント
US6579532B1 (en) * 2000-09-08 2003-06-17 Ferro Corporation Orthopedic mixtures prepared by supercritical fluid processing techniques
US6818172B2 (en) 2000-09-29 2004-11-16 Depuy Products, Inc. Oriented, cross-linked UHMWPE molding for orthopaedic applications
US20030208278A1 (en) * 2000-09-29 2003-11-06 Robert Richard Supercritical fluid treatment of irradiated polyethylene
US6558426B1 (en) 2000-11-28 2003-05-06 Medidea, Llc Multiple-cam, posterior-stabilized knee prosthesis
DE10105085C1 (de) * 2001-02-05 2002-04-18 Plus Endoprothetik Ag Rotkreuz Verfahren zur Herstellung von Implantatteilen aus hochvernetztem UHMWPE und deren Verwendung
JP3360073B2 (ja) * 2001-02-22 2002-12-24 花王株式会社 飲 料
US6547828B2 (en) 2001-02-23 2003-04-15 Smith & Nephew, Inc. Cross-linked ultra-high molecular weight polyethylene for medical implant use
JP3757264B2 (ja) * 2001-03-27 2006-03-22 独立行政法人産業技術総合研究所 シルセスキオキサン系ポリマー成形体及びその製造方法
US20030019106A1 (en) * 2001-04-22 2003-01-30 Diamicron, Inc. Methods for making bearings, races and components thereof having diamond and other superhard surfaces
US6655845B1 (en) * 2001-04-22 2003-12-02 Diamicron, Inc. Bearings, races and components thereof having diamond and other superhard surfaces
EP1389978B1 (de) * 2001-05-01 2009-01-07 Amedica Corporation Röntgendurchlässiges knochentransplantat
US7776085B2 (en) 2001-05-01 2010-08-17 Amedica Corporation Knee prosthesis with ceramic tibial component
US7695521B2 (en) 2001-05-01 2010-04-13 Amedica Corporation Hip prosthesis with monoblock ceramic acetabular cup
AU2002324443A1 (en) 2001-06-14 2003-01-02 Amedica Corporation Metal-ceramic composite articulation
US7182784B2 (en) * 2001-07-18 2007-02-27 Smith & Nephew, Inc. Prosthetic devices employing oxidized zirconium and other abrasion resistant surfaces contacting surfaces of cross-linked polyethylene
US6652586B2 (en) * 2001-07-18 2003-11-25 Smith & Nephew, Inc. Prosthetic devices employing oxidized zirconium and other abrasion resistant surfaces contacting surfaces of cross-linked polyethylene
GB0122117D0 (en) * 2001-09-13 2001-10-31 United Ind Operations Ltd Method of crosslinking polyolefins
DE10149884B4 (de) * 2001-10-10 2005-02-17 Hubert Rosing Verfahren zur Herstellung von Halbzeugen aus hoch- oder ultrahochmolekularen Polymeren, derart hergestellte Halbzeuge sowie deren Verwendung
US7150853B2 (en) * 2001-11-01 2006-12-19 Advanced Cardiovascular Systems, Inc. Method of sterilizing a medical device
DE10160329A1 (de) * 2001-12-07 2003-06-18 Merck Patent Gmbh Polymerbasierter Werkstoff enthaltend Silicapartikel
US7160492B2 (en) * 2001-12-12 2007-01-09 Depuy Products, Inc. Orthopaedic device for implantation in the body of an animal and method for making the same
US6852772B2 (en) * 2002-01-04 2005-02-08 Massachusetts Gerneral Hospital High modulus crosslinked polyethylene with reduced residual free radical concentration prepared below the melt
US7819925B2 (en) * 2002-01-28 2010-10-26 Depuy Products, Inc. Composite prosthetic bearing having a crosslinked articulating surface and method for making the same
EP1332735B1 (de) 2002-01-28 2007-08-08 Depuy Products, Inc. Herstellungsverfahren eines Komposit-Prothesenlagerelements mit einer vernetzten Gelenkfläche
US7186364B2 (en) * 2002-01-28 2007-03-06 Depuy Products, Inc. Composite prosthetic bearing constructed of polyethylene and an ethylene-acrylate copolymer and method for making the same
DE60302760T2 (de) 2002-01-29 2006-08-10 Paul Smith Sintern von ultrahochmolekularem polyethylen
EP1369094B1 (de) 2002-05-31 2014-11-26 Zimmer GmbH Implantat und Verfahren zur Herstellung eines steril verpackten Implantats
CA2429930C (en) 2002-06-06 2008-10-14 Howmedica Osteonics Corp. Sequentially cross-linked polyethylene
US20040002770A1 (en) * 2002-06-28 2004-01-01 King Richard S. Polymer-bioceramic composite for orthopaedic applications and method of manufacture thereof
KR101103197B1 (ko) * 2002-12-10 2012-01-04 디에스엠 아이피 어셋츠 비.브이. 폴리올레핀 섬유의 제조 방법 및 전환 방법
AU2003297195A1 (en) 2002-12-17 2004-07-22 Amedica Corporation Total disc implant
CA2513538C (en) 2003-01-16 2010-08-24 Massachusetts General Hospital Methods for making oxidation resistant polymeric material
US7938861B2 (en) * 2003-04-15 2011-05-10 Depuy Products, Inc. Implantable orthopaedic device and method for making the same
EP1624906A1 (de) * 2003-05-19 2006-02-15 Tjaart Andries Du Plessis Darstellung eines osteoinduktiven mittels
US20060243624A1 (en) * 2003-06-10 2006-11-02 Meadwestvaco Corporation Resin packaging
US20040262809A1 (en) * 2003-06-30 2004-12-30 Smith Todd S. Crosslinked polymeric composite for orthopaedic implants
US20040265165A1 (en) * 2003-06-30 2004-12-30 Depuy Products, Inc. Free radical quench process for irradiated ultrahigh molecular weight polyethylene
US7214764B2 (en) * 2003-06-30 2007-05-08 Depuy Products, Inc. Free radical quench process for irradiated ultrahigh molecular weight polyethylene
US20050133277A1 (en) * 2003-08-28 2005-06-23 Diamicron, Inc. Superhard mill cutters and related methods
US20050065307A1 (en) * 2003-09-19 2005-03-24 Depuy Products, Inc. Medical implant or medical implant part comprising porous UHMWPE and process for producing the same
US6996952B2 (en) * 2003-09-30 2006-02-14 Codman & Shurtleff, Inc. Method for improving stability and effectivity of a drug-device combination product
US7205051B2 (en) 2003-09-30 2007-04-17 Depuy Products, Inc. Medical implant or medical implant part
ES2622873T3 (es) * 2004-03-11 2017-07-07 Acumed Llc Sistemas para el reemplazo óseo
WO2005110276A1 (en) 2004-05-11 2005-11-24 The General Hospital Corporation Dba Massachusetts General Hospital Methods for making oxidation resistant polymeric material
US7384430B2 (en) * 2004-06-30 2008-06-10 Depuy Products, Inc. Low crystalline polymeric material for orthopaedic implants and an associated method
US7462318B2 (en) * 2004-10-07 2008-12-09 Biomet Manufacturing Corp. Crosslinked polymeric material with enhanced strength and process for manufacturing
US7344672B2 (en) 2004-10-07 2008-03-18 Biomet Manufacturing Corp. Solid state deformation processing of crosslinked high molecular weight polymeric materials
US7547405B2 (en) 2004-10-07 2009-06-16 Biomet Manufacturing Corp. Solid state deformation processing of crosslinked high molecular weight polymeric materials
US8262976B2 (en) 2004-10-07 2012-09-11 Biomet Manufacturing Corp. Solid state deformation processing of crosslinked high molecular weight polymeric materials
US20060142868A1 (en) * 2004-12-21 2006-06-29 Zimmer Technology, Inc. Selective crosslinking of orthopaedic implants
US7335697B2 (en) * 2004-12-23 2008-02-26 Depuy Products, Inc. Polymer composition comprising cross-linked polyethylene and methods for making the same
US7896921B2 (en) * 2004-12-30 2011-03-01 Depuy Products, Inc. Orthopaedic bearing and method for making the same
US7879275B2 (en) * 2004-12-30 2011-02-01 Depuy Products, Inc. Orthopaedic bearing and method for making the same
US7883653B2 (en) 2004-12-30 2011-02-08 Depuy Products, Inc. Method of making an implantable orthopaedic bearing
US7435372B2 (en) * 2005-03-31 2008-10-14 Zimmer, Inc. Liquid bath annealing of polymers for orthopaedic implants
US8449991B2 (en) * 2005-04-07 2013-05-28 Dimicron, Inc. Use of SN and pore size control to improve biocompatibility in polycrystalline diamond compacts
CN101166531A (zh) * 2005-04-20 2008-04-23 日绊株式会社 经皮吸收制剂
WO2006130869A1 (en) * 2005-06-02 2006-12-07 Alza Corporation Method for terminal sterilization of transdermal delivery devices
AU2006252377A1 (en) * 2005-06-02 2006-12-07 Alza Corporation Method for terminal sterilization of transdermal delivery devices
WO2006138247A2 (en) 2005-06-14 2006-12-28 Omni Life Science, Inc Crosslinked polyethylene article
US7538379B1 (en) * 2005-06-15 2009-05-26 Actel Corporation Non-volatile two-transistor programmable logic cell and array layout
ES2509884T3 (es) 2005-08-18 2014-10-20 Zimmer Gmbh Artículos de polietileno de peso molecular ultra-alto y métodos para formar artículos de polietileno de peso molecular ultra-alto
AU2006283601B2 (en) * 2005-08-22 2011-10-20 The General Hospital Corporation Dba Massachusetts General Hospital Oxidation resistant homogenized polymeric material
US8343230B2 (en) * 2005-09-22 2013-01-01 Depuy Products, Inc. Orthopaedic bearing material
US20070077268A1 (en) * 2005-09-30 2007-04-05 Depuy Products, Inc. Hydrophobic carrier modified implants for beneficial agent delivery
US8252058B2 (en) 2006-02-16 2012-08-28 Amedica Corporation Spinal implant with elliptical articulatory interface
US20070209957A1 (en) * 2006-03-09 2007-09-13 Sdgi Holdings, Inc. Packaging system for medical devices
US7812098B2 (en) * 2006-03-31 2010-10-12 Depuy Products, Inc. Bearing material of medical implant having reduced wear rate and method for reducing wear rate
US20070232716A1 (en) * 2006-04-04 2007-10-04 Fina Technology, Inc. Cross-linking resins
US20080036111A1 (en) * 2006-08-09 2008-02-14 Dehchuan Sun Non-oxidizing thermally crosslinked polymeric material and medical implant
DE602007009345D1 (de) 2006-08-25 2010-11-04 Depuy Products Inc Material zum Tragen eines medizinischen Implantats
ES2615462T3 (es) * 2006-09-01 2017-06-07 Basf Se Recuperación de ligandos de bisfenol durante la preparación de isopulegol
US8871131B2 (en) * 2006-10-30 2014-10-28 Smith And Nephew Orthopaedics Ag Processes comprising crosslinking polyethylene or using crosslinked polyethylene
WO2008118247A1 (en) 2007-01-10 2008-10-02 Biomet Manufacturing Corp. Knee joint prosthesis system and method for implantation
US8328873B2 (en) 2007-01-10 2012-12-11 Biomet Manufacturing Corp. Knee joint prosthesis system and method for implantation
US8562616B2 (en) 2007-10-10 2013-10-22 Biomet Manufacturing, Llc Knee joint prosthesis system and method for implantation
US8187280B2 (en) 2007-10-10 2012-05-29 Biomet Manufacturing Corp. Knee joint prosthesis system and method for implantation
US8163028B2 (en) 2007-01-10 2012-04-24 Biomet Manufacturing Corp. Knee joint prosthesis system and method for implantation
WO2008092047A1 (en) 2007-01-25 2008-07-31 The General Hospital Corporation Methods for making oxidation-resistant cross-linked polymeric materials
WO2008101134A1 (en) * 2007-02-14 2008-08-21 Brigham And Women's Hospital, Inc. Crosslinked polymers and methods of making the same
US20100144930A1 (en) * 2007-03-20 2010-06-10 Smith & Nephew Orthopaedics Ag Oxidation resistant highly-crosslinked uhmwpe
US9260801B2 (en) * 2007-03-27 2016-02-16 Dsm Ip Assets B.V. Process for removing residual spin solvent from a gel spun filament, the filament, multi-filament yarn and products comprising the filament
EP2150285B1 (de) 2007-04-10 2012-02-08 Zimmer, Inc. Antioxidans-stabilisiertes vernetztes ultrahochmolekulares polyethylen für anwendungen in medizinprodukten
US8664290B2 (en) 2007-04-10 2014-03-04 Zimmer, Inc. Antioxidant stabilized crosslinked ultra-high molecular weight polyethylene for medical device applications
US8641959B2 (en) 2007-07-27 2014-02-04 Biomet Manufacturing, Llc Antioxidant doping of crosslinked polymers to form non-eluting bearing components
WO2009032909A2 (en) * 2007-09-04 2009-03-12 Smith & Nephew Orthopaedics Ag Ultra high molecular weight polyethylene for bearing surfaces
US20110035018A1 (en) * 2007-09-25 2011-02-10 Depuy Products, Inc. Prosthesis with composite component
US8128703B2 (en) * 2007-09-28 2012-03-06 Depuy Products, Inc. Fixed-bearing knee prosthesis having interchangeable components
US8715359B2 (en) 2009-10-30 2014-05-06 Depuy (Ireland) Prosthesis for cemented fixation and method for making the prosthesis
US8632600B2 (en) 2007-09-25 2014-01-21 Depuy (Ireland) Prosthesis with modular extensions
US20110035017A1 (en) * 2007-09-25 2011-02-10 Depuy Products, Inc. Prosthesis with cut-off pegs and surgical method
US9204967B2 (en) 2007-09-28 2015-12-08 Depuy (Ireland) Fixed-bearing knee prosthesis having interchangeable components
KR20100080503A (ko) * 2007-10-12 2010-07-08 피크 플라스틱 앤 메탈 프로덕츠 (인터내셔널) 리미티드 엇물림형 벽 구조물을 포함하는 웨이퍼 컨테이너
EP2207848B1 (de) * 2007-11-06 2011-10-19 DSM IP Assets B.V. Verfahren zur herstellung von polyethylen mit ultrahohem molekulargewicht
CA2712559C (en) 2008-01-30 2015-03-31 Zimmer, Inc. Orthopedic component of low stiffness
CN102089333B (zh) * 2008-05-13 2014-05-28 史密夫和内修整形外科股份公司 抗氧化的高度交联的uhmwpe
US20090288366A1 (en) * 2008-05-23 2009-11-26 Phillip Andrew Schorr Vacuum packaged products and methods for making same
US9095324B2 (en) * 2008-06-20 2015-08-04 Boston Scientific Scimed, Inc. Package assembly
US9119723B2 (en) 2008-06-30 2015-09-01 Depuy (Ireland) Posterior stabilized orthopaedic prosthesis assembly
US8236061B2 (en) 2008-06-30 2012-08-07 Depuy Products, Inc. Orthopaedic knee prosthesis having controlled condylar curvature
US9168145B2 (en) 2008-06-30 2015-10-27 Depuy (Ireland) Posterior stabilized orthopaedic knee prosthesis having controlled condylar curvature
US8187335B2 (en) 2008-06-30 2012-05-29 Depuy Products, Inc. Posterior stabilized orthopaedic knee prosthesis having controlled condylar curvature
US8828086B2 (en) 2008-06-30 2014-09-09 Depuy (Ireland) Orthopaedic femoral component having controlled condylar curvature
US8206451B2 (en) 2008-06-30 2012-06-26 Depuy Products, Inc. Posterior stabilized orthopaedic prosthesis
US8192498B2 (en) 2008-06-30 2012-06-05 Depuy Products, Inc. Posterior cructiate-retaining orthopaedic knee prosthesis having controlled condylar curvature
US20100022677A1 (en) * 2008-07-24 2010-01-28 Zimmer, Inc. Reduction of free radicals in crosslinked polyethylene by infrared heating
US20100022678A1 (en) * 2008-07-24 2010-01-28 Zimmer, Inc. Reduction of free radicals in crosslinked polyethylene by infrared heating
US8133436B2 (en) * 2008-08-05 2012-03-13 Howmedica Osteonics Corp. Polyethylene cross-linked with an anthocyanin
US8765040B2 (en) * 2008-08-11 2014-07-01 Abbott Cardiovascular Systems Inc. Medical device fabrication process including strain induced crystallization with enhanced crystallization
DE102008053793A1 (de) 2008-10-21 2010-04-22 Aesculap Ag Antioxidativ wirksames, synthetisches Polymermaterial
EP2346941A1 (de) 2008-11-20 2011-07-27 Zimmer GmbH Polyethylenmaterialien
US11213397B2 (en) 2009-05-21 2022-01-04 Depuy Ireland Unlimited Company Prosthesis with surfaces having different textures and method of making the prosthesis
US9101476B2 (en) 2009-05-21 2015-08-11 Depuy (Ireland) Prosthesis with surfaces having different textures and method of making the prosthesis
US8663359B2 (en) 2009-06-26 2014-03-04 Dimicron, Inc. Thick sintered polycrystalline diamond and sintered jewelry
EP2606857A1 (de) 2009-10-30 2013-06-26 DePuy Products, Inc. Prothese mit Verbundstoffkomponente
EP2730253B1 (de) 2009-10-30 2016-03-16 DePuy Synthes Products, LLC Prothese mit Oberflächen unterschiedlicher Texturen
DK2316384T3 (da) 2009-10-30 2013-07-01 Depuy Products Inc Protese med modulære udvidelser
DK2316382T3 (da) 2009-10-30 2014-05-12 Depuy Ireland Protese til ucementeret fiksering
EP2319460A1 (de) 2009-10-30 2011-05-11 DePuy Products, Inc. Prothese mit stumpfen Zapfen
US9011547B2 (en) 2010-01-21 2015-04-21 Depuy (Ireland) Knee prosthesis system
ES2640314T3 (es) 2010-01-22 2017-11-02 Allegiance Corporation Métodos para envasar y esterilizar artículos elastoméricos y artículos elastoméricos envasados producidos mediante los mismos
US8613880B2 (en) 2010-04-21 2013-12-24 Abbott Cardiovascular Systems Inc. Post electron beam conditioning of polymeric medical devices
US8715569B2 (en) * 2010-08-20 2014-05-06 Abbott Cardiovascular Systems Inc. Post electron beam stabilization of polymeric medical devices
US9132209B2 (en) 2010-05-07 2015-09-15 Howmedia Osteonics Corp. Surface crosslinked polyethylene
US8399535B2 (en) 2010-06-10 2013-03-19 Zimmer, Inc. Polymer [[s]] compositions including an antioxidant
US8235209B2 (en) 2010-08-11 2012-08-07 Boston Scientific Scimed, Inc. Medical device packaging and methods for preparing and packaging medical devices
US8973748B2 (en) 2011-01-19 2015-03-10 Boston Scientific Scime, Inc. Medical device packaging and methods for preparing and packaging medical devices
US9096368B2 (en) 2011-01-19 2015-08-04 Boston Scientific Scimed, Inc. Medical device packaging and methods for preparing and packaging medical devices
US8966868B2 (en) * 2011-05-09 2015-03-03 Abbott Cardiovascular Systems Inc. Methods of stabilizing molecular weight of polymer stents after sterilization
US8556970B2 (en) 2011-09-28 2013-10-15 Depuy Mitek, Llc Graft introducer
US20140262858A1 (en) * 2011-10-21 2014-09-18 Ranbaxy Laboratories Limited Packaging for alitretinoin
DE102012010155B4 (de) 2012-05-24 2015-06-11 Pan-Biotech Gmbh Zellkulturbehälter für den Einmalgebrauch
GB2507640B (en) 2012-09-10 2015-08-26 Acumed Llc Radial head prosthesis with floating articular member
AU2014230834B9 (en) 2013-03-14 2017-08-31 Fresenius Kabi Deutschland Gmbh Injectable morphine formulations
US9248229B2 (en) 2013-03-14 2016-02-02 Becton, Dickinson France S.A.S. Packaging system for oxygen-sensitive drugs
US9237953B2 (en) 2013-03-15 2016-01-19 Depuy (Ireland) Mechanical assembly of pegs to prosthesis
US20160279055A1 (en) 2013-07-22 2016-09-29 Imprimis Pharmaceuticals, Inc. Pharmaceutical ophthalmic compositions for intraocular administration and methods for fabricating thereof
US9586370B2 (en) 2013-08-15 2017-03-07 Biomet Manufacturing, Llc Method for making ultra high molecular weight polyethylene
WO2015050851A1 (en) 2013-10-01 2015-04-09 Zimmer, Inc. Polymer compositions comprising one or more protected antioxidants
US9144499B2 (en) 2013-12-17 2015-09-29 Depuy (Ireland) Low profile mobile/fixed prosthetic knee systems
CA2942565A1 (en) 2014-03-12 2015-09-17 Zimmer, Inc. Melt-stabilized ultra high molecular weight polyethylene and method of making the same
US20150266210A1 (en) 2014-03-21 2015-09-24 Howmedica Osteonics Corp. Annealing method for cross-linked polyethylene
EP3227360A1 (de) 2014-12-03 2017-10-11 Zimmer, Inc. Mit antioxidationsmittel infundiertes polyethylen mit ultrahohem molekulargewicht
US9763792B2 (en) 2015-10-01 2017-09-19 Acumed Llc Radial head prosthesis with rotate-to-lock interface
US10070959B2 (en) 2016-09-28 2018-09-11 DePuy Synthes Products, Inc. Method of texturing prosthetic implants
WO2021154204A1 (en) 2020-01-27 2021-08-05 Formosa Plastics Corporation, U.S.A. Process for preparing catalysts and catalyst compositions
US11952439B2 (en) 2020-06-25 2024-04-09 b-ONE Medical (Suzhou) Co., Ltd. Surface gradient cross-linking method of ultra-high molecular weight polyethylene and the application thereof
WO2023239560A1 (en) 2022-06-09 2023-12-14 Formosa Plastics Corporaton, U.S.A. Clay composite support-activators and catalyst compositions

Family Cites Families (70)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE544324A (de) 1955-01-11
US2904480A (en) 1955-06-06 1959-09-15 Grace W R & Co Polyethylene
US3563869A (en) * 1957-11-05 1971-02-16 Grace W R & Co Irradiated polyethylene
US3022543A (en) 1958-02-07 1962-02-27 Grace W R & Co Method of producing film having improved shrink energy
US3057791A (en) 1959-07-06 1962-10-09 Phillips Petroleum Co Radiation curing of polymers
US3090770A (en) 1960-04-26 1963-05-21 Grace W R & Co Blended polyethylene compositions of improved clarity and method of making same
US3162623A (en) 1961-12-26 1964-12-22 Du Pont Crosslinking of polymers with nitrogen fluorides
US3362897A (en) * 1962-11-21 1968-01-09 Gen Electric Stable irradiated polyethylene
US3297641A (en) * 1964-01-17 1967-01-10 Grace W R & Co Process for cross-linking polyethylene
DE1241994B (de) * 1964-01-31 1967-06-08 Glanzstoff Ag Verfahren zur Absaettigung von Doppelbindungen in Polyolefinen
DE1669649B2 (de) 1966-05-27 1971-05-19 Badische Anilin- & Soda-Fabrik Ag, 6700 Ludwigshafen Verfahren zum herstellen feinteiliger schaumfoermiger olefin polymerisate mit hoher waermestandfestigkeit
US3832827A (en) 1967-12-18 1974-09-03 J Lemelson Container forming and filling apparatus
US3758273A (en) * 1970-04-03 1973-09-11 Gillette Co Processes for sterilizing polypropylene objects
GB1324919A (en) * 1970-11-13 1973-07-25 Atomic Energy Commission Preparation of filled polyethylenes
JPS526314B2 (de) 1971-11-01 1977-02-21
AU523866B2 (en) 1978-04-18 1982-08-19 Du Pont Canada Inc. Manufacture of film
US4241463A (en) 1978-10-16 1980-12-30 Precision Cast Specialties, Inc. Prosthetic implant device
JPH0149611B2 (de) * 1979-06-06 1989-10-25 Nat Res Dev
US5017627A (en) 1980-10-09 1991-05-21 National Research Development Corporation Composite material for use in orthopaedics
US4586995A (en) * 1982-09-17 1986-05-06 Phillips Petroleum Company Polymer and irradiation treatment method
JPS5971830A (ja) 1982-10-18 1984-04-23 Nippon Sheet Glass Co Ltd 屈折率分布型レンズ体の製造方法
GB8332952D0 (en) * 1983-12-09 1984-01-18 Ward I M Polymer irradiation
US4587163A (en) * 1984-03-06 1986-05-06 Zachariades Anagnostis E Preparation of ultra high molecular weight polyethylene morphologies of totally fused particles with superior mechanical performance
DE3582744D1 (de) * 1984-03-30 1991-06-13 Nat Res Dev Rohrfoermige gegenstaende.
ATE54094T1 (de) * 1984-04-13 1990-07-15 Nat Res Dev Verfahren zum verformen im festen zustand.
US4655769A (en) * 1984-10-24 1987-04-07 Zachariades Anagnostis E Ultra-high-molecular-weight polyethylene products including vascular prosthesis devices and methods relating thereto and employing pseudo-gel states
US4820466A (en) * 1985-01-31 1989-04-11 Zachariades Anagnostis E Process for obtaining ultra-high modulus products
US4950151A (en) * 1985-01-31 1990-08-21 Zachariades Anagnostic E Rolling die for producing high modulus products
ZA86528B (en) 1985-01-31 1986-09-24 Himont Inc Polypropylene with free-end long chain branching,process for making it,and use thereof
DE3545116A1 (de) 1985-05-17 1986-11-20 Transaktor KB International, Göteborg Flasche fuer wassernotverpflegung und verfahren zur herstellung einer flasche mit wassernotverpflegung
US4701288A (en) 1985-06-05 1987-10-20 Bausch & Lomb Incorporated Method of making articles of dissimilar polymer compositions
JPS6274364A (ja) * 1985-09-27 1987-04-06 株式会社 ニツシヨ− 医療用具
US4965846A (en) * 1986-08-11 1990-10-23 Baxter International Inc. Pivot pin bearing/seal with loose eyelet especially suited for disposable continuous flow blood filtration system cartridges
GB2207436B (en) * 1987-07-24 1991-07-24 Nat Research And Dev Corp The Solid phase deformation process
US5047446A (en) 1988-07-22 1991-09-10 Himont Incorporated Thermal treatment of irradiated propylene polymer material
GB8827967D0 (en) * 1988-11-30 1989-01-05 Ward I M Die-free drawing
ATE122901T1 (de) * 1988-12-02 1995-06-15 Du Pont Verfahren zur herstellung von gegenständen aus polyethylen mit ultrahohem molekulargewicht.
JPH04502028A (ja) * 1988-12-02 1992-04-09 イー・アイ・デユポン・ドウ・ヌムール・アンド・カンパニー 超高分子量直鎖ポリエチレン、製品及び製造法
US5030402A (en) * 1989-03-17 1991-07-09 Zachariades Anagnostis E Process for producing a new class of ultra-high-molecular-weight polyethylene orthopaedic prostheses with enhanced mechanical properties
US5037928A (en) * 1989-10-24 1991-08-06 E. I. Du Pont De Nemours And Company Process of manufacturing ultrahigh molecular weight linear polyethylene shaped articles
US5160677A (en) 1989-12-15 1992-11-03 United States Surgical Corporation Pressurized powder support for treating processes
CA2031406C (en) 1989-12-21 2002-05-28 Paolo Galli Graft copolymers of polyolefins and a method of producing same
US5153039A (en) * 1990-03-20 1992-10-06 Paxon Polymer Company, L.P. High density polyethylene article with oxygen barrier properties
US5200439A (en) * 1990-04-13 1993-04-06 Mitsui Toatsu Chemicals, Inc. Method for increasing intrinsic viscosity of syndiotactic polypropylene
NL9001745A (nl) 1990-08-01 1992-03-02 Stamicarbon Oplossing van ultra-hoog moleculair polyetheen.
US5352732A (en) * 1990-08-07 1994-10-04 E. I. Du Pont De Nemours And Company Homogeneous, high modulus ultrahigh molecular weight polyethylene composites and processes for the preparation thereof
US5292584A (en) 1991-04-11 1994-03-08 E. I. Du Pont De Nemours And Company Ultrahigh molecular weight polyethylene and lightly-filled composites thereof
US5508319A (en) * 1991-06-21 1996-04-16 Montell North America Inc. High melt strength, ethylene polymer, process for making it, and use thereof
US5505984A (en) * 1993-01-21 1996-04-09 England; Garry L. Method for forming biocompatible components using an isostatic press
US5414049A (en) * 1993-06-01 1995-05-09 Howmedica Inc. Non-oxidizing polymeric medical implant
EP0714460A4 (de) 1993-08-20 1998-01-07 Smith & Nephew Richards Inc Selbstverstärkte verbundwerkstoffe aus polyethylen mit sehr hohem molekulargewicht
EP0729981B1 (de) 1994-09-21 2002-03-20 Bmg Incorporated Polyethylenguss mit ultrahohem molekulargewicht für künstliche verbindungen und verfahren zu dessen herstellung
CA2166450C (en) * 1995-01-20 2008-03-25 Ronald Salovey Chemically crosslinked ultrahigh molecular weight polyethylene for artificial human joints
US5609643A (en) 1995-03-13 1997-03-11 Johnson & Johnson Professional, Inc. Knee joint prosthesis
US5577368A (en) 1995-04-03 1996-11-26 Johnson & Johnson Professional, Inc. Method for improving wear resistance of polymeric bioimplantable components
US5879400A (en) * 1996-02-13 1999-03-09 Massachusetts Institute Of Technology Melt-irradiated ultra high molecular weight polyethylene prosthetic devices
PL189246B1 (pl) * 1996-02-13 2005-07-29 Gen Hospital Corp Sposób otrzymywania usieciowanego polietylenu o ultrawysokim ciężarze cząsteczkowym, medyczna proteza do stosowania wewnątrz ciała oraz zastosowanie poddanego działaniu promieniowania polietylenu o ultrawysokim ciężarze cząsteczkowym
US5753182A (en) * 1996-02-14 1998-05-19 Biomet, Inc. Method for reducing the number of free radicals present in ultrahigh molecular weight polyethylene orthopedic components
US6228900B1 (en) * 1996-07-09 2001-05-08 The Orthopaedic Hospital And University Of Southern California Crosslinking of polyethylene for low wear using radiation and thermal treatments
US6017975A (en) * 1996-10-02 2000-01-25 Saum; Kenneth Ashley Process for medical implant of cross-linked ultrahigh molecular weight polyethylene having improved balance of wear properties and oxidation resistance
EP1028760B1 (de) * 1996-10-15 2004-04-14 Orthopaedic Hospital Verschleissfestes vernetztes polyethylen mit oberflächengradienten
US5874123A (en) * 1997-01-24 1999-02-23 Park; Joon B. Precoated polymeric prosthesis and process for making same
US6432349B1 (en) * 1999-06-29 2002-08-13 Zimmer, Inc. Process of making an articulating bearing surface
US6143232A (en) * 1999-07-29 2000-11-07 Bristol-Meyers Squibb Company Method of manufacturing an articulating bearing surface for an orthopaedic implant
US6184265B1 (en) * 1999-07-29 2001-02-06 Depuy Orthopaedics, Inc. Low temperature pressure stabilization of implant component
JP4400970B2 (ja) * 1999-11-22 2010-01-20 若井産業株式会社 ナットの包装方法と包装体
WO2001052110A2 (en) * 2000-01-13 2001-07-19 Orbidex, Inc. System and method of searching and gathering information on-line and off-line
US6395799B1 (en) * 2000-02-21 2002-05-28 Smith & Nephew, Inc. Electromagnetic and mechanical wave energy treatments of UHMWPE
US6503439B1 (en) * 2000-06-15 2003-01-07 Albert H. Burstein Process for forming shaped articles of ultra high molecular weight polyethylene suitable for use as a prosthetic device or a component thereof
US6547828B2 (en) * 2001-02-23 2003-04-15 Smith & Nephew, Inc. Cross-linked ultra-high molecular weight polyethylene for medical implant use

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US5650485A (en) 1997-07-22
DE69425838T2 (de) 2001-04-12
EP0847765A1 (de) 1998-06-17
ATE171078T1 (de) 1998-10-15
US5543471A (en) 1996-08-06
AU6436494A (en) 1994-12-20
CA2162927C (en) 2000-07-04
DE69425838D1 (de) 2000-10-12
US6818020B2 (en) 2004-11-16
JPH08509148A (ja) 1996-10-01
EP1598086A2 (de) 2005-11-23
US20050059750A1 (en) 2005-03-17
DE9490446U1 (de) 1997-02-20
JP2836965B2 (ja) 1998-12-14
ES2122260T3 (es) 1998-12-16
ATE302032T1 (de) 2005-09-15
EP1005872A1 (de) 2000-06-07
US20020107299A1 (en) 2002-08-08
DE69413395T2 (de) 1999-02-04
US6372814B1 (en) 2002-04-16
US20030207957A1 (en) 2003-11-06
EP0701453A1 (de) 1996-03-20
EP1005872B1 (de) 2005-08-17
AU684500B2 (en) 1997-12-18
US5449745A (en) 1995-09-12
WO1994027651A1 (en) 1994-12-08
DE69434462T2 (de) 2006-06-08
DE69434462D1 (de) 2005-09-22
ATE196095T1 (de) 2000-09-15
EP0847765B1 (de) 2000-09-06
US6664308B2 (en) 2003-12-16
EP0701453B1 (de) 1998-09-16
US5728748A (en) 1998-03-17
US5414049A (en) 1995-05-09
US6174934B1 (en) 2001-01-16

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