DE69207681T2 - Verfahren zur Herstellung von einer Alpha-Aminosäure, und dem entsprechenden Ester und Amid - Google Patents

Verfahren zur Herstellung von einer Alpha-Aminosäure, und dem entsprechenden Ester und Amid

Info

Publication number
DE69207681T2
DE69207681T2 DE69207681T DE69207681T DE69207681T2 DE 69207681 T2 DE69207681 T2 DE 69207681T2 DE 69207681 T DE69207681 T DE 69207681T DE 69207681 T DE69207681 T DE 69207681T DE 69207681 T2 DE69207681 T2 DE 69207681T2
Authority
DE
Germany
Prior art keywords
acid
amino acid
mol
water
added
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69207681T
Other languages
German (de)
English (en)
Other versions
DE69207681D1 (de
Inventor
Wilhelmus Hubertus Jos Boesten
Heij Nicolaas Antonius De
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
DSM IP Assets BV
Original Assignee
DSM NV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by DSM NV filed Critical DSM NV
Publication of DE69207681D1 publication Critical patent/DE69207681D1/de
Application granted granted Critical
Publication of DE69207681T2 publication Critical patent/DE69207681T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C229/04—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C231/00—Preparation of carboxylic acid amides
    • C07C231/14—Preparation of carboxylic acid amides by formation of carboxamide groups together with reactions not involving the carboxamide groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C227/04—Formation of amino groups in compounds containing carboxyl groups
    • C07C227/10—Formation of amino groups in compounds containing carboxyl groups with simultaneously increasing the number of carbon atoms in the carbon skeleton

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
DE69207681T 1991-08-13 1992-08-10 Verfahren zur Herstellung von einer Alpha-Aminosäure, und dem entsprechenden Ester und Amid Expired - Fee Related DE69207681T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
NL9101380A NL9101380A (nl) 1991-08-13 1991-08-13 Werkwijze voor de bereiding van een alfa-aminozuur, de overeenkomstige ester en amide.

Publications (2)

Publication Number Publication Date
DE69207681D1 DE69207681D1 (de) 1996-02-29
DE69207681T2 true DE69207681T2 (de) 1996-09-26

Family

ID=19859606

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69207681T Expired - Fee Related DE69207681T2 (de) 1991-08-13 1992-08-10 Verfahren zur Herstellung von einer Alpha-Aminosäure, und dem entsprechenden Ester und Amid

Country Status (11)

Country Link
US (1) US5336805A (enExample)
EP (1) EP0530879B1 (enExample)
JP (1) JP3190442B2 (enExample)
KR (1) KR100240798B1 (enExample)
AT (1) ATE133160T1 (enExample)
CZ (1) CZ290435B6 (enExample)
DE (1) DE69207681T2 (enExample)
ES (1) ES2084263T3 (enExample)
HU (1) HU212878B (enExample)
NL (1) NL9101380A (enExample)
TW (1) TW207990B (enExample)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4443892A1 (de) * 1994-12-09 1996-06-13 Bayer Ag 4-(Chinolin-2-yl-methoxy)-phenyl-essigsäurederivate
DE10048715A1 (de) * 2000-09-30 2004-05-19 Grünenthal GmbH Verwendung von Aminosäure zur Behandlung von Schmerz
CN101362703B (zh) * 2007-08-09 2011-11-16 谢建中 对羟基苯甘氨酸合成技术
WO2009127446A1 (en) * 2008-04-17 2009-10-22 Deretil, S.A. METHOD FOR THE PREPARATION OF D-p-HYDROXYPHENYLGLYCINE
US8940928B2 (en) 2012-02-15 2015-01-27 Henan Newland Pharmaceutical Co., Ltd. Method of synthesizing levorotatory p-hydroxyphenylglycine compounds
CN104370765A (zh) * 2013-08-13 2015-02-25 成都化工股份有限公司 D-苯甘氨酸和dl-苯甘氨酸的合成方法
CN106631850B (zh) * 2016-09-14 2019-05-24 山东汉兴医药科技有限公司 一种对羟基苯甘氨酸合成的后处理工艺
CN113861054B (zh) * 2021-12-02 2022-02-08 天津市职业大学 一种固体磷酸催化合成对羟基苯甘氨酸的方法
CN115784913B (zh) * 2022-11-28 2025-03-21 湖北省宏源药业科技股份有限公司 一种d，l-对羟基苯甘氨酸的生产方法及装置

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH365385A (de) * 1958-01-13 1962-11-15 Geigy Ag J R Verfahren zur Herstellung von a-substituierten Glycinen bzw. Glycinestern
US4205185A (en) * 1970-07-11 1980-05-27 Sterling Drug Inc. Process for preparing racemic 4-hydroxyphenylglycine
GB1371896A (en) * 1970-10-15 1974-10-30 Beecham Group Ltd Hydroxyaryl amino acids
JPS5917104B2 (ja) * 1977-05-02 1984-04-19 田辺製薬株式会社 ヒドロキシフエニルグリシン類化合物の製法
EP0001060B1 (de) * 1977-08-30 1982-10-06 Riedel-De Haen Aktiengesellschaft Verfahren zur Herstellung von optisch aktiver, ggf. substituierter 2-Amino-2-phenylessigsäure
JPS5446741A (en) * 1977-09-16 1979-04-12 Tanabe Seiyaku Co Ltd Preparation of hydroxy-phenyl glycine derivatives
JPS5461191A (en) * 1977-10-18 1979-05-17 Toray Ind Inc Preparation of 7beta-amino-3-methyl-3-cephem-4-carboxylic acids
GB2090595B (en) * 1978-11-25 1983-05-11 Nippon Kayaku Kk Threo-3-amino-2-hydroxybutanoylacetice acid derivatives

Also Published As

Publication number Publication date
DE69207681D1 (de) 1996-02-29
US5336805A (en) 1994-08-09
EP0530879B1 (en) 1996-01-17
HUT61969A (en) 1993-03-29
TW207990B (enExample) 1993-06-21
HU212878B (en) 1996-12-30
KR100240798B1 (ko) 2000-02-01
CZ290435B6 (cs) 2002-07-17
ES2084263T3 (es) 1996-05-01
CZ249592A3 (en) 1993-02-17
ATE133160T1 (de) 1996-02-15
EP0530879A1 (en) 1993-03-10
JP3190442B2 (ja) 2001-07-23
JPH05194337A (ja) 1993-08-03
NL9101380A (nl) 1993-03-01
KR930004248A (ko) 1993-03-22

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: DSM IP ASSETS B.V., HEERLEN, NL

8339 Ceased/non-payment of the annual fee