DE69121489T2 - In vitro-Behandlung von Fusionsproteinen - Google Patents
In vitro-Behandlung von FusionsproteinenInfo
- Publication number
- DE69121489T2 DE69121489T2 DE69121489T DE69121489T DE69121489T2 DE 69121489 T2 DE69121489 T2 DE 69121489T2 DE 69121489 T DE69121489 T DE 69121489T DE 69121489 T DE69121489 T DE 69121489T DE 69121489 T2 DE69121489 T2 DE 69121489T2
- Authority
- DE
- Germany
- Prior art keywords
- protein
- amino acid
- biologically active
- soluble
- lys
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
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- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
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- C07K—PEPTIDES
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- C07K14/575—Hormones
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- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
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- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C07K2319/70—Fusion polypeptide containing domain for protein-protein interaction
- C07K2319/74—Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor
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- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Enzymes And Modification Thereof (AREA)
- Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB909015825A GB9015825D0 (en) | 1990-07-18 | 1990-07-18 | In vitro processing of fusion proteins |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE69121489D1 DE69121489D1 (de) | 1996-09-26 |
| DE69121489T2 true DE69121489T2 (de) | 1997-02-27 |
Family
ID=10679295
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE69121489T Expired - Fee Related DE69121489T2 (de) | 1990-07-18 | 1991-07-09 | In vitro-Behandlung von Fusionsproteinen |
Country Status (19)
| Country | Link |
|---|---|
| EP (1) | EP0467839B1 (enExample) |
| JP (1) | JP3140488B2 (enExample) |
| AT (1) | ATE141645T1 (enExample) |
| AU (1) | AU651830B2 (enExample) |
| CA (1) | CA2047119C (enExample) |
| DE (1) | DE69121489T2 (enExample) |
| DK (1) | DK0467839T3 (enExample) |
| ES (1) | ES2091897T3 (enExample) |
| FI (1) | FI106720B (enExample) |
| GB (1) | GB9015825D0 (enExample) |
| GR (1) | GR3020840T3 (enExample) |
| HU (1) | HU216104B (enExample) |
| IE (1) | IE73209B1 (enExample) |
| NO (1) | NO303132B1 (enExample) |
| NZ (1) | NZ238989A (enExample) |
| PT (1) | PT98332B (enExample) |
| SG (1) | SG49863A1 (enExample) |
| TW (1) | TW209247B (enExample) |
| ZA (1) | ZA915579B (enExample) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5525491A (en) * | 1991-02-27 | 1996-06-11 | Creative Biomolecules, Inc. | Serine-rich peptide linkers |
| EP0816510A4 (en) * | 1995-12-22 | 2001-04-11 | Toray Industries | PROCESS FOR PRODUCING BIOLOGICALLY ACTIVE FUSED PROTEINS |
| US6800726B1 (en) | 1996-11-01 | 2004-10-05 | Pioneer Hi-Bred International, Inc. | Proteins with increased levels of essential amino acids |
| US6265204B1 (en) | 1997-01-17 | 2001-07-24 | Genencor International, Inc. | DNA sequences, vectors, and fusion polypeptides for secretion of polypeptides in filamentous fungi |
| GB9716790D0 (en) | 1997-08-07 | 1997-10-15 | Creative Peptides Sweden Ab | Recombinant DNA molecules comprising multimeric copies of a gene sequence and expression thereof |
| US9926570B2 (en) | 2013-03-06 | 2018-03-27 | Glaxosmithkline Llc | Host cells and methods of use |
| CN118515782B (zh) * | 2024-06-03 | 2025-03-18 | 浙江毓昌生物技术有限公司 | 一种融合蛋白及基于该融合蛋白制备重组人生长激素的方法 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MC1834A1 (fr) * | 1986-07-10 | 1988-06-03 | Transgene Sa | Bloc fonctionnel d'adn et plasmide codant pour l'hirudine,levure transformee,procede de preparation de l'hirudine,hirudine obtenue et son utilisation |
| US5010182A (en) * | 1987-07-28 | 1991-04-23 | Chiron Corporation | DNA constructs containing a Kluyveromyces alpha factor leader sequence for directing secretion of heterologous polypeptides |
| DK105489D0 (da) * | 1989-03-03 | 1989-03-03 | Novo Nordisk As | Polypeptid |
-
1990
- 1990-07-18 GB GB909015825A patent/GB9015825D0/en active Pending
-
1991
- 1991-07-09 SG SG9607721A patent/SG49863A1/en unknown
- 1991-07-09 AT AT91810543T patent/ATE141645T1/de not_active IP Right Cessation
- 1991-07-09 EP EP91810543A patent/EP0467839B1/en not_active Expired - Lifetime
- 1991-07-09 DE DE69121489T patent/DE69121489T2/de not_active Expired - Fee Related
- 1991-07-09 DK DK91810543.8T patent/DK0467839T3/da active
- 1991-07-09 ES ES91810543T patent/ES2091897T3/es not_active Expired - Lifetime
- 1991-07-15 FI FI913405A patent/FI106720B/fi active
- 1991-07-16 AU AU80463/91A patent/AU651830B2/en not_active Ceased
- 1991-07-16 NZ NZ238989A patent/NZ238989A/en not_active IP Right Cessation
- 1991-07-16 PT PT98332A patent/PT98332B/pt not_active IP Right Cessation
- 1991-07-16 CA CA002047119A patent/CA2047119C/en not_active Expired - Lifetime
- 1991-07-17 ZA ZA915579A patent/ZA915579B/xx unknown
- 1991-07-17 IE IE250191A patent/IE73209B1/en not_active IP Right Cessation
- 1991-07-17 HU HU2398/91A patent/HU216104B/hu not_active IP Right Cessation
- 1991-07-17 JP JP03176552A patent/JP3140488B2/ja not_active Expired - Fee Related
- 1991-07-17 NO NO912803A patent/NO303132B1/no not_active IP Right Cessation
- 1991-07-17 TW TW080105554A patent/TW209247B/zh active
-
1996
- 1996-08-22 GR GR960402054T patent/GR3020840T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| AU8046391A (en) | 1992-01-23 |
| HU912398D0 (en) | 1991-12-30 |
| AU651830B2 (en) | 1994-08-04 |
| NO303132B1 (no) | 1998-06-02 |
| CA2047119C (en) | 2002-10-08 |
| ZA915579B (en) | 1992-03-25 |
| GR3020840T3 (en) | 1996-11-30 |
| DE69121489D1 (de) | 1996-09-26 |
| SG49863A1 (en) | 2002-03-19 |
| ES2091897T3 (es) | 1996-11-16 |
| TW209247B (enExample) | 1993-07-11 |
| PT98332A (pt) | 1992-05-29 |
| FI106720B (fi) | 2001-03-30 |
| EP0467839A1 (en) | 1992-01-22 |
| PT98332B (pt) | 1999-01-29 |
| IE912501A1 (en) | 1992-01-29 |
| DK0467839T3 (da) | 1996-09-16 |
| HU216104B (hu) | 1999-04-28 |
| FI913405A7 (fi) | 1992-01-19 |
| GB9015825D0 (en) | 1990-09-05 |
| CA2047119A1 (en) | 1992-01-19 |
| FI913405A0 (fi) | 1991-07-15 |
| HUT58369A (en) | 1992-02-28 |
| JPH04229188A (ja) | 1992-08-18 |
| NO912803D0 (no) | 1991-07-17 |
| EP0467839B1 (en) | 1996-08-21 |
| NO912803L (no) | 1992-01-20 |
| JP3140488B2 (ja) | 2001-03-05 |
| ATE141645T1 (de) | 1996-09-15 |
| NZ238989A (en) | 1992-09-25 |
| IE73209B1 (en) | 1997-05-07 |
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Legal Events
| Date | Code | Title | Description |
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| 8327 | Change in the person/name/address of the patent owner |
Owner name: NOVARTIS AG, BASEL, CH |
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| 8364 | No opposition during term of opposition | ||
| 8328 | Change in the person/name/address of the agent |
Representative=s name: PFENNING MEINIG & PARTNER GBR, 80339 MUENCHEN |
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| 8328 | Change in the person/name/address of the agent |
Representative=s name: MAIWALD PATENTANWALTSGESELLSCHAFT MBH, 80335 MUENC |
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| 8339 | Ceased/non-payment of the annual fee |