DE69004372T2 - Verfahren zum Mikronisieren schwerlöslicher Arzneistoffe. - Google Patents

Verfahren zum Mikronisieren schwerlöslicher Arzneistoffe.

Info

Publication number
DE69004372T2
DE69004372T2 DE90114858T DE69004372T DE69004372T2 DE 69004372 T2 DE69004372 T2 DE 69004372T2 DE 90114858 T DE90114858 T DE 90114858T DE 69004372 T DE69004372 T DE 69004372T DE 69004372 T2 DE69004372 T2 DE 69004372T2
Authority
DE
Germany
Prior art keywords
micronizing
poorly soluble
soluble drugs
drug
comminution
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE90114858T
Other languages
English (en)
Other versions
DE69004372D1 (de
Inventor
Masayoshi Samejima
Kazuo Noda
Masao Kobayashi
Takashi Osawa
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Tanabe Seiyaku Co Ltd
Original Assignee
Tanabe Seiyaku Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tanabe Seiyaku Co Ltd filed Critical Tanabe Seiyaku Co Ltd
Publication of DE69004372D1 publication Critical patent/DE69004372D1/de
Application granted granted Critical
Publication of DE69004372T2 publication Critical patent/DE69004372T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/145—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic compounds

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
DE90114858T 1989-08-04 1990-08-02 Verfahren zum Mikronisieren schwerlöslicher Arzneistoffe. Expired - Fee Related DE69004372T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP1204132A JP2642486B2 (ja) 1989-08-04 1989-08-04 難溶性薬物の超微粒子化法

Publications (2)

Publication Number Publication Date
DE69004372D1 DE69004372D1 (de) 1993-12-09
DE69004372T2 true DE69004372T2 (de) 1994-04-21

Family

ID=16485367

Family Applications (1)

Application Number Title Priority Date Filing Date
DE90114858T Expired - Fee Related DE69004372T2 (de) 1989-08-04 1990-08-02 Verfahren zum Mikronisieren schwerlöslicher Arzneistoffe.

Country Status (9)

Country Link
US (1) US5202129A (de)
EP (1) EP0411629B1 (de)
JP (1) JP2642486B2 (de)
KR (1) KR0126465B1 (de)
AT (1) ATE96658T1 (de)
CA (1) CA2022465C (de)
DE (1) DE69004372T2 (de)
DK (1) DK0411629T3 (de)
ES (1) ES2062221T3 (de)

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US5747445A (en) * 1993-06-24 1998-05-05 Astra Aktiebolag Therapeutic preparation for inhalation
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Also Published As

Publication number Publication date
JP2642486B2 (ja) 1997-08-20
CA2022465C (en) 1998-04-21
EP0411629A2 (de) 1991-02-06
DE69004372D1 (de) 1993-12-09
KR0126465B1 (ko) 1997-12-24
EP0411629A3 (en) 1991-05-08
KR910004183A (ko) 1991-03-28
EP0411629B1 (de) 1993-11-03
ES2062221T3 (es) 1994-12-16
ATE96658T1 (de) 1993-11-15
DK0411629T3 (da) 1993-12-13
US5202129A (en) 1993-04-13
JPH0366613A (ja) 1991-03-22
CA2022465A1 (en) 1991-02-05

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