ATE119393T1 - Verwendung eines opiatantagonisten zur herstellung eines transdermal zu verabreichenden arzneimittels sowie eine vorrichtung zur transdermalen verabreichung. - Google Patents
Verwendung eines opiatantagonisten zur herstellung eines transdermal zu verabreichenden arzneimittels sowie eine vorrichtung zur transdermalen verabreichung.Info
- Publication number
- ATE119393T1 ATE119393T1 AT90122076T AT90122076T ATE119393T1 AT E119393 T1 ATE119393 T1 AT E119393T1 AT 90122076 T AT90122076 T AT 90122076T AT 90122076 T AT90122076 T AT 90122076T AT E119393 T1 ATE119393 T1 AT E119393T1
- Authority
- AT
- Austria
- Prior art keywords
- transdermal administration
- producing
- opiate antagonist
- medicinal product
- antagonist
- Prior art date
Links
- 239000003401 opiate antagonist Substances 0.000 title abstract 3
- 229940126601 medicinal product Drugs 0.000 title 1
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 1
- 239000005557 antagonist Substances 0.000 abstract 1
- 239000003961 penetration enhancing agent Substances 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/485—Morphinan derivatives, e.g. morphine, codeine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Emergency Medicine (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US07/439,050 US5096715A (en) | 1989-11-20 | 1989-11-20 | Method and means for treating alcoholism by extinguishing the alcohol-drinking response using a transdermally administered opiate antagonist |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE119393T1 true ATE119393T1 (de) | 1995-03-15 |
Family
ID=23743078
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT90122076T ATE119393T1 (de) | 1989-11-20 | 1990-11-19 | Verwendung eines opiatantagonisten zur herstellung eines transdermal zu verabreichenden arzneimittels sowie eine vorrichtung zur transdermalen verabreichung. |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US5096715A (de) |
| EP (1) | EP0429039B1 (de) |
| AT (1) | ATE119393T1 (de) |
| AU (1) | AU639042B2 (de) |
| CA (1) | CA2030237C (de) |
| DE (1) | DE69017596T2 (de) |
| DK (1) | DK0429039T3 (de) |
| ES (1) | ES2074513T3 (de) |
| FI (1) | FI905718A7 (de) |
| NZ (2) | NZ247173A (de) |
Families Citing this family (58)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5086058A (en) * | 1990-06-04 | 1992-02-04 | Alko Ltd. | Method for treating alcoholism with nalmefene |
| DE4223004A1 (de) * | 1992-07-13 | 1994-01-20 | Liedtke Pharmed Gmbh | Einzeldosierte halbfeste topische Arzneiform zur Transdermaltherapie |
| US5580876A (en) * | 1992-09-21 | 1996-12-03 | Albert Einstein College Of Medicine Of Yeshiva University, A Division Of Yeshiva University | Method of simultaneously enhancing analgesic potency and attenuating dependence liability caused by morphine and other bimodally-acting opioid agonists |
| USRE36547E (en) * | 1992-09-21 | 2000-02-01 | Albert Einstein College Of Medicine Of Yeshiva University | Method of simultaneously enhancing analgesic potency and attenuating dependence liability caused by exogenous and endogenous opioid agonists |
| US6096756A (en) * | 1992-09-21 | 2000-08-01 | Albert Einstein College Of Medicine Of Yeshiva University | Method of simultaneously enhancing analgesic potency and attenuating dependence liability caused by morphine and other bimodally-acting opioid agonists |
| US5580574A (en) * | 1994-04-28 | 1996-12-03 | Hoffmann-La Roche Inc. | Pharmaceutical composition for transdermal delivery |
| US5552153A (en) * | 1994-04-28 | 1996-09-03 | Hoffman-La Roche Inc. | Pharmaceutical composition for transdermal delivery |
| DE4423850A1 (de) * | 1994-07-07 | 1996-01-11 | Labtec Gmbh | Transdermales therapeutisches System zur Applikation von Naloxon |
| US5587381A (en) * | 1995-03-27 | 1996-12-24 | Sinclair; John D. | Method for terminating methadone maintenance through extinction of the opiate-taking responses |
| BR9813826A (pt) * | 1997-12-22 | 2000-10-10 | Euro Celtique Sa | Potencial de uso abusivo de administração oral de opióide analgésico |
| US6375957B1 (en) | 1997-12-22 | 2002-04-23 | Euro-Celtique, S.A. | Opioid agonist/opioid antagonist/acetaminophen combinations |
| EP2266564B1 (de) * | 1997-12-22 | 2013-03-13 | Euro-Celtique S.A. | Peroral zu verabreichende Arzneiform enthaltend eine Kombination von einem opioid Agonisten und einem opioid Antagonisten |
| MXPA00012844A (es) | 1998-07-07 | 2004-05-21 | Transdermal Technologies Inc | Composiciones para la liberacion transdermica rapida y sin irritacion de agentes farmaceuticamente activos y metodos para formular tales composiciones y liberar los mismos. |
| AU1807401A (en) * | 1999-11-30 | 2001-06-12 | Corixa Corporation | Compositions and methods for therapy and diagnosis of breast cancer |
| EP2517710B1 (de) | 2000-02-08 | 2015-03-25 | Euro-Celtique S.A. | Missbrauchssichere orale Opioidagonisten-Formulierungen |
| US6716449B2 (en) | 2000-02-08 | 2004-04-06 | Euro-Celtique S.A. | Controlled-release compositions containing opioid agonist and antagonist |
| US20040024004A1 (en) * | 2001-05-04 | 2004-02-05 | Sherman Barry M. | Novel compositions and methods for enhancing potency or reducing adverse side effects of opioid agonists |
| US20060121103A1 (en) * | 2000-05-11 | 2006-06-08 | Kenneth Kirby | Transdermal delivery system |
| US6569449B1 (en) | 2000-11-13 | 2003-05-27 | University Of Kentucky Research Foundation | Transdermal delivery of opioid antagonist prodrugs |
| JP4522652B2 (ja) | 2001-05-11 | 2010-08-11 | エンドー ファーマシューティカルズ, インコーポレイティド | 乱用防止制御放出オピオイド投薬形態 |
| WO2003006980A1 (en) * | 2001-07-13 | 2003-01-23 | Arkray, Inc. | Analyzing apparatus, piercing element integrally installed body for temperature measuring device with analyzing apparatus, and body fluid sampling apparatus |
| CA2454328C (en) * | 2001-07-18 | 2008-03-18 | Christopher D. Breder | Pharmaceutical combinations of oxycodone and naloxone |
| MXPA04001210A (es) | 2001-08-06 | 2004-07-08 | Euro Celtique Sa | Formulaciones de agonista opioide con antagonista liberable y aislado. |
| US20030044458A1 (en) * | 2001-08-06 | 2003-03-06 | Curtis Wright | Oral dosage form comprising a therapeutic agent and an adverse-effect agent |
| US20030157168A1 (en) * | 2001-08-06 | 2003-08-21 | Christopher Breder | Sequestered antagonist formulations |
| HUP0401022A3 (en) * | 2001-08-14 | 2006-11-28 | Biotie Therapies Corp | Method for the preparation of pharmaceutical compositions containing opioid antagonist for treating alcoholism or alcohol abuse |
| US20040033253A1 (en) * | 2002-02-19 | 2004-02-19 | Ihor Shevchuk | Acyl opioid antagonists |
| LT2425824T (lt) | 2002-04-05 | 2017-07-25 | Euro-Celtique S.A. | Farmacinis preparatas, turintis oksikodono ir naloksono |
| SI1551372T1 (en) * | 2002-09-20 | 2018-08-31 | Alpharma Pharmaceuticals Llc | SUBVENCATION DATA AND RELATED CONSTRUCTIONS AND PROCEDURES |
| US20040202717A1 (en) * | 2003-04-08 | 2004-10-14 | Mehta Atul M. | Abuse-resistant oral dosage forms and method of use thereof |
| EP1613324A2 (de) * | 2003-04-14 | 2006-01-11 | Pain Therapeutics, Inc. | Verfahren zur behandlung von schmerzen mit opioid-antagonisten |
| MY135852A (en) * | 2003-04-21 | 2008-07-31 | Euro Celtique Sa | Pharmaceutical products |
| US20060009478A1 (en) * | 2003-10-15 | 2006-01-12 | Nadav Friedmann | Methods for the treatment of back pain |
| EP1604666A1 (de) * | 2004-06-08 | 2005-12-14 | Euro-Celtique S.A. | Opioide zur Behandlung der chronischen obstruktiven Lungenkrankheit |
| JP2008514612A (ja) * | 2004-09-23 | 2008-05-08 | ミシャロウ、アレクサンダー | 対抗適応を誘発することにより神経伝達物質系を調節する方法 |
| US20080045610A1 (en) * | 2004-09-23 | 2008-02-21 | Alexander Michalow | Methods for regulating neurotransmitter systems by inducing counteradaptations |
| US7910599B2 (en) | 2005-01-10 | 2011-03-22 | John David Sinclair | Method for treating eating disorders by selective extinction with transdermal naloxone |
| EP1702558A1 (de) * | 2005-02-28 | 2006-09-20 | Euro-Celtique S.A. | Verfahren und Vorrichtung zur Darmtätigkeitserfassung |
| US8852638B2 (en) | 2005-09-30 | 2014-10-07 | Durect Corporation | Sustained release small molecule drug formulation |
| EP2719378B1 (de) * | 2006-06-19 | 2016-08-31 | Alpharma Pharmaceuticals LLC | Pharmazeutische Zusammensetzungen |
| JP2010531807A (ja) | 2007-05-25 | 2010-09-30 | トルマー セラピューティクス, インコーポレイテッド | リスペリドン化合物の徐放送達製剤 |
| US20100151014A1 (en) * | 2008-12-16 | 2010-06-17 | Alpharma Pharmaceuticals, Llc | Pharmaceutical composition |
| EP2224808A4 (de) * | 2007-12-17 | 2013-11-27 | Alpharma Pharmaceuticals Llc | Pharmazeutische zusammensetzung |
| US8623418B2 (en) * | 2007-12-17 | 2014-01-07 | Alpharma Pharmaceuticals Llc | Pharmaceutical composition |
| WO2009106831A2 (en) | 2008-02-28 | 2009-09-03 | Syntropharma Limited | Pharmaceutical composition |
| AU2009268011B2 (en) * | 2008-07-07 | 2013-02-28 | Mundipharma Pty Limited | Use of opioid antagonists for treating urinary retention |
| HUE042105T2 (hu) | 2009-03-10 | 2019-06-28 | Euro Celtique Sa | Oxikodont és naloxont tartalmazó azonnali hatóanyagleadású orális gyógyászati készítmények |
| WO2011064769A1 (en) | 2009-11-24 | 2011-06-03 | Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. | Methods and pharmaceutical compositions for the treatment of hot flashes |
| US9272044B2 (en) | 2010-06-08 | 2016-03-01 | Indivior Uk Limited | Injectable flowable composition buprenorphine |
| GB2513060B (en) | 2010-06-08 | 2015-01-07 | Rb Pharmaceuticals Ltd | Microparticle buprenorphine suspension |
| US8627816B2 (en) | 2011-02-28 | 2014-01-14 | Intelliject, Inc. | Medicament delivery device for administration of opioid antagonists including formulations for naloxone |
| US8939943B2 (en) | 2011-01-26 | 2015-01-27 | Kaleo, Inc. | Medicament delivery device for administration of opioid antagonists including formulations for naloxone |
| EP3024461B1 (de) | 2013-07-23 | 2020-05-13 | Euro-Celtique S.A. | Kombination aus oxycodon und naloxon für die verwendung bei der behandlung von schmerzen bei patienten mit schmerzen und einer krankheit, die zur intestinaldysbiose und/oder erhöhung der gefahr bakterieller translokation führt |
| GB201404139D0 (en) | 2014-03-10 | 2014-04-23 | Rb Pharmaceuticals Ltd | Sustained release buprenorphine solution formulations |
| US11607026B2 (en) * | 2014-05-30 | 2023-03-21 | Johnson & Johnson Consumer Inc. | Device for delivery of skin care composition |
| US9517307B2 (en) | 2014-07-18 | 2016-12-13 | Kaleo, Inc. | Devices and methods for delivering opioid antagonists including formulations for naloxone |
| WO2019113470A1 (en) * | 2017-12-08 | 2019-06-13 | Teikoku Pharma Usa, Inc. | Naloxone transdermal delivery devices and methods for using the same |
| EP4103181A4 (de) * | 2020-02-14 | 2024-03-06 | Teikoku Pharma USA, Inc. | Topische naloxonzusammensetzung und verfahren zu deren verwendung |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2837881A (en) * | 1952-12-13 | 1958-06-10 | Lawrence A Schneider | Encapsulated product and method and apparatus for making same |
| US3249109A (en) * | 1963-11-01 | 1966-05-03 | Maeth Harry | Topical dressing |
| US4351337A (en) * | 1973-05-17 | 1982-09-28 | Arthur D. Little, Inc. | Biodegradable, implantable drug delivery device, and process for preparing and using the same |
| IE49783B1 (en) * | 1979-05-18 | 1985-12-11 | Efamol Ltd | Pharmaceutical and dietary composition comprising epsilon-linolenic acids |
| US4629539A (en) * | 1982-07-08 | 1986-12-16 | Tdk Corporation | Metal layer patterning method |
| EP0116538A4 (de) * | 1982-08-25 | 1985-04-25 | Joel E Bernstein | Verfahren zur behandlung von pruritis und zusammensetzung dazu. |
| US4626539A (en) * | 1984-08-10 | 1986-12-02 | E. I. Dupont De Nemours And Company | Trandermal delivery of opioids |
| US4573995A (en) * | 1984-10-09 | 1986-03-04 | Alza Corporation | Transdermal therapeutic systems for the administration of naloxone, naltrexone and nalbuphine |
| US4818540A (en) * | 1985-02-25 | 1989-04-04 | Rutgers, The State University Of New Jersey | Transdermal fertility control system and process |
| US4806341A (en) * | 1985-02-25 | 1989-02-21 | Rutgers, The State University Of New Jersey | Transdermal absorption dosage unit for narcotic analgesics and antagonists and process for administration |
| US4680172A (en) * | 1985-03-05 | 1987-07-14 | Ciba-Geigy Corporation | Devices and methods for treating memory impairment |
| US4645502A (en) * | 1985-05-03 | 1987-02-24 | Alza Corporation | Transdermal delivery of highly ionized fat insoluble drugs |
| DE3545926A1 (de) * | 1985-12-23 | 1987-07-02 | Allan Gerhard Fruehauf | Tuch oder dgl. mit darin integrierten, einen wirkstoff enthaltenden kapseln |
| ATE77559T1 (de) * | 1986-11-14 | 1992-07-15 | Theratech Inc | Erhoehung des penetrationsvermoegens mittels eines aus die zellhuelle veraendernden substanzen und kurzkettigen alkoholen bestehenden binaeren systems. |
| DE3862405D1 (de) * | 1987-03-09 | 1991-05-23 | Alza Corp | Zusammensetzung zur vorbeugung einer kontaktallergie durch gleichzeitiges verabreichen eines kortikosteroids mit einem sensiblisierenden arzneistoff. |
| US4882335A (en) * | 1988-06-13 | 1989-11-21 | Alko Limited | Method for treating alcohol-drinking response |
-
1989
- 1989-11-20 US US07/439,050 patent/US5096715A/en not_active Expired - Lifetime
-
1990
- 1990-11-14 AU AU66650/90A patent/AU639042B2/en not_active Expired
- 1990-11-16 NZ NZ247173A patent/NZ247173A/en unknown
- 1990-11-16 NZ NZ236104A patent/NZ236104A/xx unknown
- 1990-11-19 DE DE69017596T patent/DE69017596T2/de not_active Expired - Lifetime
- 1990-11-19 EP EP90122076A patent/EP0429039B1/de not_active Expired - Lifetime
- 1990-11-19 ES ES90122076T patent/ES2074513T3/es not_active Expired - Lifetime
- 1990-11-19 AT AT90122076T patent/ATE119393T1/de not_active IP Right Cessation
- 1990-11-19 CA CA002030237A patent/CA2030237C/en not_active Expired - Lifetime
- 1990-11-19 DK DK90122076.4T patent/DK0429039T3/da active
- 1990-11-20 FI FI905718A patent/FI905718A7/fi not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| CA2030237A1 (en) | 1991-05-21 |
| CA2030237C (en) | 1997-12-30 |
| DK0429039T3 (da) | 1995-03-27 |
| US5096715A (en) | 1992-03-17 |
| AU6665090A (en) | 1991-05-23 |
| NZ236104A (en) | 1993-04-28 |
| ES2074513T3 (es) | 1995-09-16 |
| DE69017596T2 (de) | 1995-07-06 |
| FI905718L (fi) | 1991-05-21 |
| FI905718A7 (fi) | 1991-05-21 |
| DE69017596D1 (de) | 1995-04-13 |
| EP0429039A3 (en) | 1991-10-16 |
| FI905718A0 (fi) | 1990-11-20 |
| NZ247173A (en) | 1997-07-27 |
| EP0429039A2 (de) | 1991-05-29 |
| EP0429039B1 (de) | 1995-03-08 |
| AU639042B2 (en) | 1993-07-15 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EELA | Cancelled due to lapse of time |