ATE119393T1 - Verwendung eines opiatantagonisten zur herstellung eines transdermal zu verabreichenden arzneimittels sowie eine vorrichtung zur transdermalen verabreichung. - Google Patents

Verwendung eines opiatantagonisten zur herstellung eines transdermal zu verabreichenden arzneimittels sowie eine vorrichtung zur transdermalen verabreichung.

Info

Publication number
ATE119393T1
ATE119393T1 AT90122076T AT90122076T ATE119393T1 AT E119393 T1 ATE119393 T1 AT E119393T1 AT 90122076 T AT90122076 T AT 90122076T AT 90122076 T AT90122076 T AT 90122076T AT E119393 T1 ATE119393 T1 AT E119393T1
Authority
AT
Austria
Prior art keywords
transdermal administration
producing
opiate antagonist
medicinal product
antagonist
Prior art date
Application number
AT90122076T
Other languages
English (en)
Inventor
John David Sinclair
Original Assignee
Alko Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alko Ltd filed Critical Alko Ltd
Application granted granted Critical
Publication of ATE119393T1 publication Critical patent/ATE119393T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/485—Morphinan derivatives, e.g. morphine, codeine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Emergency Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AT90122076T 1989-11-20 1990-11-19 Verwendung eines opiatantagonisten zur herstellung eines transdermal zu verabreichenden arzneimittels sowie eine vorrichtung zur transdermalen verabreichung. ATE119393T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/439,050 US5096715A (en) 1989-11-20 1989-11-20 Method and means for treating alcoholism by extinguishing the alcohol-drinking response using a transdermally administered opiate antagonist

Publications (1)

Publication Number Publication Date
ATE119393T1 true ATE119393T1 (de) 1995-03-15

Family

ID=23743078

Family Applications (1)

Application Number Title Priority Date Filing Date
AT90122076T ATE119393T1 (de) 1989-11-20 1990-11-19 Verwendung eines opiatantagonisten zur herstellung eines transdermal zu verabreichenden arzneimittels sowie eine vorrichtung zur transdermalen verabreichung.

Country Status (10)

Country Link
US (1) US5096715A (de)
EP (1) EP0429039B1 (de)
AT (1) ATE119393T1 (de)
AU (1) AU639042B2 (de)
CA (1) CA2030237C (de)
DE (1) DE69017596T2 (de)
DK (1) DK0429039T3 (de)
ES (1) ES2074513T3 (de)
FI (1) FI905718A (de)
NZ (2) NZ236104A (de)

Families Citing this family (58)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5086058A (en) * 1990-06-04 1992-02-04 Alko Ltd. Method for treating alcoholism with nalmefene
DE4223004A1 (de) * 1992-07-13 1994-01-20 Liedtke Pharmed Gmbh Einzeldosierte halbfeste topische Arzneiform zur Transdermaltherapie
US6096756A (en) 1992-09-21 2000-08-01 Albert Einstein College Of Medicine Of Yeshiva University Method of simultaneously enhancing analgesic potency and attenuating dependence liability caused by morphine and other bimodally-acting opioid agonists
US5580876A (en) * 1992-09-21 1996-12-03 Albert Einstein College Of Medicine Of Yeshiva University, A Division Of Yeshiva University Method of simultaneously enhancing analgesic potency and attenuating dependence liability caused by morphine and other bimodally-acting opioid agonists
USRE36547E (en) * 1992-09-21 2000-02-01 Albert Einstein College Of Medicine Of Yeshiva University Method of simultaneously enhancing analgesic potency and attenuating dependence liability caused by exogenous and endogenous opioid agonists
US5580574A (en) * 1994-04-28 1996-12-03 Hoffmann-La Roche Inc. Pharmaceutical composition for transdermal delivery
US5552153A (en) * 1994-04-28 1996-09-03 Hoffman-La Roche Inc. Pharmaceutical composition for transdermal delivery
DE4423850A1 (de) * 1994-07-07 1996-01-11 Labtec Gmbh Transdermales therapeutisches System zur Applikation von Naloxon
US5587381A (en) * 1995-03-27 1996-12-24 Sinclair; John D. Method for terminating methadone maintenance through extinction of the opiate-taking responses
RS50070B (sr) 1997-12-22 2009-01-22 Euro-Celtique S.A., Oralni dozni oblik sa kombinacijom opijatnog agonista i antagonista
US6228863B1 (en) * 1997-12-22 2001-05-08 Euro-Celtique S.A. Method of preventing abuse of opioid dosage forms
US6375957B1 (en) 1997-12-22 2002-04-23 Euro-Celtique, S.A. Opioid agonist/opioid antagonist/acetaminophen combinations
MXPA00012844A (es) * 1998-07-07 2004-05-21 Transdermal Technologies Inc Composiciones para la liberacion transdermica rapida y sin irritacion de agentes farmaceuticamente activos y metodos para formular tales composiciones y liberar los mismos.
CA2392510A1 (en) * 1999-11-30 2001-06-07 Corixa Corporation Compositions and methods for therapy and diagnosis of breast cancer
JP2003522146A (ja) * 2000-02-08 2003-07-22 ユーロ−セルティーク，エス．エイ． 外圧に抵抗性の経口オピオイドアゴニスト製剤
US6716449B2 (en) 2000-02-08 2004-04-06 Euro-Celtique S.A. Controlled-release compositions containing opioid agonist and antagonist
US20040024004A1 (en) * 2001-05-04 2004-02-05 Sherman Barry M. Novel compositions and methods for enhancing potency or reducing adverse side effects of opioid agonists
US20060121103A1 (en) * 2000-05-11 2006-06-08 Kenneth Kirby Transdermal delivery system
US6569449B1 (en) 2000-11-13 2003-05-27 University Of Kentucky Research Foundation Transdermal delivery of opioid antagonist prodrugs
ATE493130T1 (de) 2001-05-11 2011-01-15 Endo Pharmaceuticals Inc Opioid enthaltende arzneiform gegen missbrauch
JP4736323B2 (ja) * 2001-07-13 2011-07-27 アークレイ株式会社 分析用具を備えた濃度測定装置用の穿刺要素一体装着体、および体液採取用具
DK1416842T3 (da) * 2001-07-18 2009-03-16 Euro Celtique Sa Farmaceutiske kombinationer af oxycodon og naloxon
NZ530971A (en) 2001-08-06 2004-08-27 Euro Celtique S Oral dosage forms comprising an opioid agonist with releasable and sequestered opioid antagonists
US20030044458A1 (en) * 2001-08-06 2003-03-06 Curtis Wright Oral dosage form comprising a therapeutic agent and an adverse-effect agent
US20030157168A1 (en) * 2001-08-06 2003-08-21 Christopher Breder Sequestered antagonist formulations
HUP0401022A3 (en) * 2001-08-14 2006-11-28 Biotie Therapies Corp Method for the preparation of pharmaceutical compositions containing opioid antagonist for treating alcoholism or alcohol abuse
US20040033253A1 (en) * 2002-02-19 2004-02-19 Ihor Shevchuk Acyl opioid antagonists
EP1492505B1 (de) 2002-04-05 2015-06-03 Euro-Celtique S.A. Pharmazeutische zubereitung enthaltend oxycodon und naloxon
AU2003270778B2 (en) * 2002-09-20 2009-10-08 Alpharma Pharmaceuticals, Llc Sequestering subunit and related compositions and methods
US20040202717A1 (en) * 2003-04-08 2004-10-14 Mehta Atul M. Abuse-resistant oral dosage forms and method of use thereof
EP1613324A2 (de) * 2003-04-14 2006-01-11 Pain Therapeutics, Inc. Verfahren zur behandlung von schmerzen mit opioid-antagonisten
TWI347201B (en) 2003-04-21 2011-08-21 Euro Celtique Sa Pharmaceutical products,uses thereof and methods for preparing the same
US20060009478A1 (en) * 2003-10-15 2006-01-12 Nadav Friedmann Methods for the treatment of back pain
EP1604666A1 (de) * 2004-06-08 2005-12-14 Euro-Celtique S.A. Opioide zur Behandlung der chronischen obstruktiven Lungenkrankheit
US20080045610A1 (en) * 2004-09-23 2008-02-21 Alexander Michalow Methods for regulating neurotransmitter systems by inducing counteradaptations
US20060069086A1 (en) * 2004-09-23 2006-03-30 Alexander Michalow Methods for regulating neurotransmitter systems by inducing counteradaptations
US7910599B2 (en) 2005-01-10 2011-03-22 John David Sinclair Method for treating eating disorders by selective extinction with transdermal naloxone
EP1702558A1 (de) * 2005-02-28 2006-09-20 Euro-Celtique S.A. Verfahren und Vorrichtung zur Darmtätigkeitserfassung
US8852638B2 (en) 2005-09-30 2014-10-07 Durect Corporation Sustained release small molecule drug formulation
PT2034975E (pt) * 2006-06-19 2012-06-25 Alpharma Pharmaceuticals Llc Composições farmacêuticas
MX354603B (es) 2007-05-25 2018-03-13 Indivior Uk Ltd Formulaciones de transferencia sostenida de compuestos de risperidona.
US8623418B2 (en) * 2007-12-17 2014-01-07 Alpharma Pharmaceuticals Llc Pharmaceutical composition
WO2009088673A2 (en) * 2007-12-17 2009-07-16 Alpharma Pharmaceuticals, Llc Pharmaceutical composition
US20100151014A1 (en) * 2008-12-16 2010-06-17 Alpharma Pharmaceuticals, Llc Pharmaceutical composition
EP2259780A2 (de) * 2008-02-28 2010-12-15 Syntropharma Limited Pharmazeutische zusammensetzung mit naltrexon
KR20130105935A (ko) * 2008-07-07 2013-09-26 유로-셀티큐 에스.에이. 요폐의 치료를 위한 아편유사제 길항제의 용도
LT2405915T (lt) 2009-03-10 2019-03-12 Euro-Celtique S.A. Greito atpalaidavimo farmacinė kompozicija, apimanti oksikodoną ir naloksoną
WO2011064769A1 (en) 2009-11-24 2011-06-03 Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. Methods and pharmaceutical compositions for the treatment of hot flashes
GB2481017B (en) 2010-06-08 2015-01-07 Rb Pharmaceuticals Ltd Microparticle buprenorphine suspension
US9272044B2 (en) 2010-06-08 2016-03-01 Indivior Uk Limited Injectable flowable composition buprenorphine
US8939943B2 (en) 2011-01-26 2015-01-27 Kaleo, Inc. Medicament delivery device for administration of opioid antagonists including formulations for naloxone
US8627816B2 (en) 2011-02-28 2014-01-14 Intelliject, Inc. Medicament delivery device for administration of opioid antagonists including formulations for naloxone
AU2014295042B2 (en) 2013-07-23 2017-03-30 Mundipharma Pty Limited A combination of oxycodone and naloxone for use in treating pain in patients suffering from pain and a disease resulting in intestinal dysbiosis and/or increasing the risk for intestinal bacterial translocation
GB201404139D0 (en) 2014-03-10 2014-04-23 Rb Pharmaceuticals Ltd Sustained release buprenorphine solution formulations
US11607026B2 (en) * 2014-05-30 2023-03-21 Johnson & Johnson Consumer Inc. Device for delivery of skin care composition
US9517307B2 (en) 2014-07-18 2016-12-13 Kaleo, Inc. Devices and methods for delivering opioid antagonists including formulations for naloxone
US20190175519A1 (en) * 2017-12-08 2019-06-13 Teikoku Pharma Usa, Inc. Naloxone Transdermal Delivery Devices and Methods for Using the Same
JP7495989B2 (ja) * 2020-02-14 2024-06-05 テイコク ファーマ ユーエスエー インコーポレーテッド 局所用ナロキソン組成物およびそれを使用するための方法

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2837881A (en) * 1952-12-13 1958-06-10 Lawrence A Schneider Encapsulated product and method and apparatus for making same
US3249109A (en) * 1963-11-01 1966-05-03 Maeth Harry Topical dressing
US4351337A (en) * 1973-05-17 1982-09-28 Arthur D. Little, Inc. Biodegradable, implantable drug delivery device, and process for preparing and using the same
IE49783B1 (en) * 1979-05-18 1985-12-11 Efamol Ltd Pharmaceutical and dietary composition comprising epsilon-linolenic acids
US4629539A (en) * 1982-07-08 1986-12-16 Tdk Corporation Metal layer patterning method
JPS59501712A (ja) * 1982-08-25 1984-10-11 バ−ンステイン，ジヨエル　イ−． 「そう」痒症を治療する方法およびそのための組成物
US4626539A (en) * 1984-08-10 1986-12-02 E. I. Dupont De Nemours And Company Trandermal delivery of opioids
US4573995A (en) * 1984-10-09 1986-03-04 Alza Corporation Transdermal therapeutic systems for the administration of naloxone, naltrexone and nalbuphine
US4806341A (en) * 1985-02-25 1989-02-21 Rutgers, The State University Of New Jersey Transdermal absorption dosage unit for narcotic analgesics and antagonists and process for administration
US4818540A (en) * 1985-02-25 1989-04-04 Rutgers, The State University Of New Jersey Transdermal fertility control system and process
US4680172A (en) * 1985-03-05 1987-07-14 Ciba-Geigy Corporation Devices and methods for treating memory impairment
US4645502A (en) * 1985-05-03 1987-02-24 Alza Corporation Transdermal delivery of highly ionized fat insoluble drugs
DE3545926A1 (de) * 1985-12-23 1987-07-02 Allan Gerhard Fruehauf Tuch oder dgl. mit darin integrierten, einen wirkstoff enthaltenden kapseln
DE3779999T2 (de) * 1986-11-14 1992-12-10 Theratech Inc Erhoehung des penetrationsvermoegens mittels eines aus die zellhuelle veraendernden substanzen und kurzkettigen alkoholen bestehenden binaeren systems.
EP0282156B1 (de) * 1987-03-09 1991-04-17 Alza Corporation Zusammensetzung zur Vorbeugung einer Kontaktallergie durch gleichzeitiges Verabreichen eines Kortikosteroids mit einem sensiblisierenden Arzneistoff
US4882335A (en) * 1988-06-13 1989-11-21 Alko Limited Method for treating alcohol-drinking response

Also Published As

Publication number Publication date
DK0429039T3 (da) 1995-03-27
NZ236104A (en) 1993-04-28
US5096715A (en) 1992-03-17
ES2074513T3 (es) 1995-09-16
FI905718A0 (fi) 1990-11-20
EP0429039B1 (de) 1995-03-08
DE69017596T2 (de) 1995-07-06
CA2030237C (en) 1997-12-30
NZ247173A (en) 1997-07-27
FI905718A (fi) 1991-05-21
EP0429039A2 (de) 1991-05-29
CA2030237A1 (en) 1991-05-21
AU639042B2 (en) 1993-07-15
EP0429039A3 (en) 1991-10-16
AU6665090A (en) 1991-05-23
DE69017596D1 (de) 1995-04-13

Similar Documents

Publication Publication Date Title
ATE119393T1 (de) Verwendung eines opiatantagonisten zur herstellung eines transdermal zu verabreichenden arzneimittels sowie eine vorrichtung zur transdermalen verabreichung.
DE58906926D1 (de) Neue Arzneimittelformulierung sowie Verfahren zu deren Herstellung.
ATE204178T1 (de) Methode zur behandlung und vorbeugung von typ-1 diabetis durch orale verabreichung von insulin
ATE80997T1 (de) Verfahren zur herstellung einer darreichungsund/oder dosierungsform fuer arzneimittelwirkstoffe.
DE58903856D1 (de) Oral zu verabreichende pharmazeutische zubereitung mit kontrollierter wirkstofffreisetzung und verfahren zu deren herstellung.
ATE99172T1 (de) Verwendung von acetyl-l-carnitin zur behandlung von katarakt, sowie pharmazeutische zusammensetzungen fuer eine derartige behandlung.
ATE206914T1 (de) Verwendung von ursolsäure zur herstellung eines arzneimittels zur unterdrückung von metastasen
DE58901002D1 (de) Mittel mit zerstoerender wirkung auf maligne tumore, verfahren zu dessen herstellung und praeparation zur anwendung in der therapie von krebskranken.
ATE69724T1 (de) Selbstklebende vorrichtung zur transdermalen verabreichung eines wirkstoffs.
AU625402B2 (en) Transdermal system exhibiting graduated drug release and its use for the local or systemic administration of active substances
ATE27155T1 (de) Hexahydronaphth(1,2-b)-1,4-oxazine, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische zusammensetzungen.
KR890006227A (ko) 페놀-함유 진해성 액체 조성물
NZ245380A (en) Piperidylmethyl-substituted chroman derivatives, preparation and pharmaceutical compositions thereof
DE10004790A1 (de) Transdermales therapeutisches System zur Verabreichung von Zaleplon
DE69103624D1 (de) Ipriflavone enthaltende pharmazeutische zubereitungen, verfahren zur herstellung und therapeutische verwendung.
Gibb et al. Piritramide—a new long-acting analgesic
Thomas et al. Cardiac arrhythmia during outpatient dental anaesthesia: the advantages of a controlled ventilation technique
DE345883T1 (de) Verwendung von dapiprazol zur herstellung eines arzneimittels zur verhinderung des toleranzentwicklung bei der analgetischen behandlung mit morphin.
ATE25090T1 (de) Pharmazeutische verbindungen, deren herstellung, anwendung, deren zwischenverbindungen und herstellung.
DE3767533D1 (de) D-nor-7-ergolinderivate, verfahren zu ihrer herstellung, pharmazeutische zubereitung und verwendung.
DE3786168D1 (de) Verwendung von para-aminobenzoesaeure zur herstellung eines arzneimittels zur bekaempfung von photoallergien.
Barzaghi et al. Pharmacokinetics of dextromoramide in surgical patients
JPS56139446A (en) 10-substituted-5-cyanmethylene-dibenzo (a,d)cycloheptene, manufacture and medicine containing same
KR920700041A (ko) 치료화합물과 그의 조성 및 용도
Herman Incontinence clamp

Legal Events

Date Code Title Description
EELA Cancelled due to lapse of time