DE68912341T2 - Pharmazeutische zusammensetzungen mit gehalt an calcitonin zur intranasalen verabreichung und eine spray-einheit zur verabreichung derselben. - Google Patents
Pharmazeutische zusammensetzungen mit gehalt an calcitonin zur intranasalen verabreichung und eine spray-einheit zur verabreichung derselben.Info
- Publication number
- DE68912341T2 DE68912341T2 DE89912812T DE68912341T DE68912341T2 DE 68912341 T2 DE68912341 T2 DE 68912341T2 DE 89912812 T DE89912812 T DE 89912812T DE 68912341 T DE68912341 T DE 68912341T DE 68912341 T2 DE68912341 T2 DE 68912341T2
- Authority
- DE
- Germany
- Prior art keywords
- administration
- pharmaceutical compositions
- spray unit
- calcitonin content
- intranasal administration
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0043—Nose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/23—Calcitonins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
- B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
- B05B11/00—Single-unit hand-held apparatus in which flow of contents is produced by the muscular force of the operator at the moment of use
- B05B11/01—Single-unit hand-held apparatus in which flow of contents is produced by the muscular force of the operator at the moment of use characterised by the means producing the flow
- B05B11/10—Pump arrangements for transferring the contents from the container to a pump chamber by a sucking effect and forcing the contents out through the dispensing nozzle
- B05B11/1001—Piston pumps
- B05B11/1016—Piston pumps the outlet valve having a valve seat located downstream a movable valve element controlled by a pressure actuated controlling element
- B05B11/1018—Piston pumps the outlet valve having a valve seat located downstream a movable valve element controlled by a pressure actuated controlling element and the controlling element cooperating with means for opening or closing the inlet valve
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
- B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
- B05B11/00—Single-unit hand-held apparatus in which flow of contents is produced by the muscular force of the operator at the moment of use
- B05B11/01—Single-unit hand-held apparatus in which flow of contents is produced by the muscular force of the operator at the moment of use characterised by the means producing the flow
- B05B11/10—Pump arrangements for transferring the contents from the container to a pump chamber by a sucking effect and forcing the contents out through the dispensing nozzle
- B05B11/1042—Components or details
- B05B11/1043—Sealing or attachment arrangements between pump and container
- B05B11/1046—Sealing or attachment arrangements between pump and container the pump chamber being arranged substantially coaxially to the neck of the container
- B05B11/1047—Sealing or attachment arrangements between pump and container the pump chamber being arranged substantially coaxially to the neck of the container the pump being preassembled as an independent unit before being mounted on the container
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
- B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
- B65D83/00—Containers or packages with special means for dispensing contents
- B65D83/14—Containers or packages with special means for dispensing contents for delivery of liquid or semi-liquid contents by internal gaseous pressure, i.e. aerosol containers comprising propellant for a product delivered by a propellant
- B65D83/44—Valves specially adapted therefor; Regulating devices
- B65D83/52—Valves specially adapted therefor; Regulating devices for metering
- B65D83/54—Metering valves ; Metering valve assemblies
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Zoology (AREA)
- Endocrinology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Gastroenterology & Hepatology (AREA)
- Hematology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Mechanical Engineering (AREA)
- Obesity (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Dispersion Chemistry (AREA)
- Diabetes (AREA)
- Otolaryngology (AREA)
- Inorganic Chemistry (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Containers And Packaging Bodies Having A Special Means To Remove Contents (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT8822257A IT1227174B (it) | 1988-10-11 | 1988-10-11 | Composizioni farmaceutiche a base di calcitonina, somministrabili per via intranasale. |
IT8822548A IT1227472B (it) | 1988-11-08 | 1988-11-08 | Confezione spray per la somministrazione intranasale di calcitonina. |
PCT/EP1989/001186 WO1990003796A1 (en) | 1988-10-11 | 1989-10-09 | Pharmaceutical compositions comprising calcitonin for intranasal administration and a spray unit for the administration of the same |
Publications (2)
Publication Number | Publication Date |
---|---|
DE68912341D1 DE68912341D1 (de) | 1994-02-24 |
DE68912341T2 true DE68912341T2 (de) | 1994-05-05 |
Family
ID=26328146
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE89912812T Expired - Lifetime DE68912341T2 (de) | 1988-10-11 | 1989-10-09 | Pharmazeutische zusammensetzungen mit gehalt an calcitonin zur intranasalen verabreichung und eine spray-einheit zur verabreichung derselben. |
Country Status (19)
Country | Link |
---|---|
EP (2) | EP0363876B1 (de) |
JP (2) | JPH0649658B2 (de) |
KR (1) | KR0152065B1 (de) |
AU (1) | AU632520B2 (de) |
BR (1) | BR8907708A (de) |
CA (1) | CA2000336C (de) |
DE (1) | DE68912341T2 (de) |
DK (1) | DK64291D0 (de) |
ES (1) | ES2053905T3 (de) |
FI (1) | FI95201C (de) |
GR (1) | GR3007420T3 (de) |
HU (1) | HU212495B (de) |
IE (1) | IE62327B1 (de) |
IL (2) | IL91856A0 (de) |
NO (1) | NO301522B1 (de) |
NZ (1) | NZ230965A (de) |
RO (1) | RO113301B1 (de) |
RU (1) | RU2097064C1 (de) |
WO (1) | WO1990003796A1 (de) |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5026825A (en) * | 1988-09-08 | 1991-06-25 | Rhone-Poulenc Rorer Pharmaceuticals Inc. | Intranasal calcitonin formulations |
DE69001991T2 (de) * | 1989-11-16 | 1993-09-23 | Phidea Spa | Fluessige arzneimittel zur nasalen anwendung, die ein polypeptid als wirksubstanz enthalten. |
IT1242019B (it) * | 1990-11-20 | 1994-02-02 | Ripari Gero Ist Farm Biolog | Composizioni farmaceutiche acquose a base di calcitonina, da somministrarsi per via nasale. |
IT1282374B1 (it) * | 1996-01-31 | 1998-03-20 | Therapicon Srl | Composizioni farmaceutiche parenterali a base di calcitonine sintetiche a ph controllato con basso indice di dolorosita' |
DE19731472C2 (de) * | 1997-07-22 | 2000-05-25 | Gerhard Zellner | Nasenspray-Flüssigkeit |
IT1294191B1 (it) * | 1997-09-05 | 1999-03-22 | Alfa Wassermann Spa | Composizioni farmaceutiche contenenti calcitonina in un dosatore spray per somministrazione intranasale. |
SE9901658D0 (sv) * | 1999-05-06 | 1999-05-06 | Astra Ab | New formulation |
US6644305B2 (en) | 2000-04-14 | 2003-11-11 | Trudell Medical International | Nasal inhaler |
ATE401105T1 (de) * | 2002-09-03 | 2008-08-15 | Pharmacure Health Care Ab | Nasensprays |
CN102186598B (zh) * | 2007-11-29 | 2015-03-11 | 葛兰素集团有限公司 | 配给设备 |
GB2464282A (en) * | 2008-10-08 | 2010-04-14 | Archimedes Dev Ltd | A device for administering a dose of opioid analgesic |
EP2670674B1 (de) | 2011-02-04 | 2016-08-31 | Archimedes Development Limited | Verbesserter container |
DE102011082420B4 (de) * | 2011-09-09 | 2021-02-04 | Aptar Radolfzell Gmbh | Flüssigkeitsspender und Austragskopf für einen Flüssigkeitsspender |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ZA758010B (en) * | 1975-11-14 | 1977-08-31 | Syntex Inc | Nasal spray adapter |
GB2114001B (en) * | 1982-02-01 | 1986-06-18 | Sandoz Ltd | Nasel pharmaceutical compositions |
BE897904A (fr) * | 1982-10-05 | 1984-04-04 | Sandoz Sa | Nouvelles compositions galeniques a base de calcitonine |
FR2561565B1 (fr) * | 1984-03-23 | 1986-08-01 | Norlac Plastiques Sa | Couteau electrique destine notamment a l'ouverture des huitres |
GB8407907D0 (en) * | 1984-03-27 | 1984-05-02 | Sandoz Ltd | Organic compounds |
JPS61118325A (ja) * | 1984-11-12 | 1986-06-05 | Yamanouchi Pharmaceut Co Ltd | 塩基性および/または中性アミノ酸を含有するカルシトニン経鼻剤 |
JPS61126034A (ja) * | 1984-11-26 | 1986-06-13 | Yamanouchi Pharmaceut Co Ltd | アルド−スを含有するカルシトニン経鼻剤 |
JPS61194034A (ja) * | 1985-02-25 | 1986-08-28 | Teijin Ltd | 経鼻投与用粉末状組成物 |
JPS6310735A (ja) * | 1986-07-02 | 1988-01-18 | Yamanouchi Pharmaceut Co Ltd | カルシトニン経鼻剤 |
JPS6339822A (ja) * | 1986-08-04 | 1988-02-20 | Yamanouchi Pharmaceut Co Ltd | カルシトニン経鼻剤 |
-
1989
- 1989-10-02 IL IL91856A patent/IL91856A0/xx unknown
- 1989-10-09 IE IE325989A patent/IE62327B1/en not_active IP Right Cessation
- 1989-10-09 RU SU4895203/14A patent/RU2097064C1/ru not_active IP Right Cessation
- 1989-10-09 EP EP89118734A patent/EP0363876B1/de not_active Expired - Lifetime
- 1989-10-09 BR BR898907708A patent/BR8907708A/pt not_active IP Right Cessation
- 1989-10-09 DE DE89912812T patent/DE68912341T2/de not_active Expired - Lifetime
- 1989-10-09 JP JP2500510A patent/JPH0649658B2/ja not_active Expired - Lifetime
- 1989-10-09 EP EP89912812A patent/EP0438531B1/de not_active Expired - Lifetime
- 1989-10-09 RO RO147309A patent/RO113301B1/ro unknown
- 1989-10-09 ES ES89118734T patent/ES2053905T3/es not_active Expired - Lifetime
- 1989-10-09 KR KR1019900701225A patent/KR0152065B1/ko not_active IP Right Cessation
- 1989-10-09 AU AU46225/89A patent/AU632520B2/en not_active Ceased
- 1989-10-09 HU HU896876A patent/HU212495B/hu not_active IP Right Cessation
- 1989-10-09 WO PCT/EP1989/001186 patent/WO1990003796A1/en active IP Right Grant
- 1989-10-10 NZ NZ230965A patent/NZ230965A/en unknown
- 1989-10-10 CA CA002000336A patent/CA2000336C/en not_active Expired - Fee Related
- 1989-10-10 IL IL9193189A patent/IL91931A/en not_active IP Right Cessation
-
1991
- 1991-04-10 DK DK91642A patent/DK64291D0/da not_active Application Discontinuation
- 1991-04-10 FI FI911722A patent/FI95201C/fi not_active IP Right Cessation
- 1991-04-10 NO NO911395A patent/NO301522B1/no not_active IP Right Cessation
-
1993
- 1993-03-22 GR GR930400612T patent/GR3007420T3/el unknown
- 1993-11-30 JP JP5323298A patent/JPH0796034A/ja active Pending
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8327 | Change in the person/name/address of the patent owner |
Owner name: ALFA WASSERMANN S.P.A., ALANNO SCALO, PESCARA, IT |