DE68912341D1 - Pharmazeutische zusammensetzungen mit gehalt an calcitonin zur intranasalen verabreichung und eine spray-einheit zur verabreichung derselben. - Google Patents

Pharmazeutische zusammensetzungen mit gehalt an calcitonin zur intranasalen verabreichung und eine spray-einheit zur verabreichung derselben.

Info

Publication number
DE68912341D1
DE68912341D1 DE89912812T DE68912341T DE68912341D1 DE 68912341 D1 DE68912341 D1 DE 68912341D1 DE 89912812 T DE89912812 T DE 89912812T DE 68912341 T DE68912341 T DE 68912341T DE 68912341 D1 DE68912341 D1 DE 68912341D1
Authority
DE
Germany
Prior art keywords
administration
pharmaceutical compositions
spray unit
calcitonin content
intranasal administration
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE89912812T
Other languages
English (en)
Other versions
DE68912341T2 (de
Inventor
Salvatore Mardente
Rodolfo Corneli
Marilena Carazzone
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Alfa Wasserman SpA
Original Assignee
Schiapparelli Salute SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26328146&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE68912341(D1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from IT8822257A external-priority patent/IT1227174B/it
Priority claimed from IT8822548A external-priority patent/IT1227472B/it
Application filed by Schiapparelli Salute SpA filed Critical Schiapparelli Salute SpA
Publication of DE68912341D1 publication Critical patent/DE68912341D1/de
Application granted granted Critical
Publication of DE68912341T2 publication Critical patent/DE68912341T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0043—Nose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/23—Calcitonins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
    • B05B11/00—Single-unit hand-held apparatus in which flow of contents is produced by the muscular force of the operator at the moment of use
    • B05B11/01—Single-unit hand-held apparatus in which flow of contents is produced by the muscular force of the operator at the moment of use characterised by the means producing the flow
    • B05B11/10—Pump arrangements for transferring the contents from the container to a pump chamber by a sucking effect and forcing the contents out through the dispensing nozzle
    • B05B11/1001—Piston pumps
    • B05B11/1016—Piston pumps the outlet valve having a valve seat located downstream a movable valve element controlled by a pressure actuated controlling element
    • B05B11/1018—Piston pumps the outlet valve having a valve seat located downstream a movable valve element controlled by a pressure actuated controlling element and the controlling element cooperating with means for opening or closing the inlet valve
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
    • B05B11/00—Single-unit hand-held apparatus in which flow of contents is produced by the muscular force of the operator at the moment of use
    • B05B11/01—Single-unit hand-held apparatus in which flow of contents is produced by the muscular force of the operator at the moment of use characterised by the means producing the flow
    • B05B11/10—Pump arrangements for transferring the contents from the container to a pump chamber by a sucking effect and forcing the contents out through the dispensing nozzle
    • B05B11/1042—Components or details
    • B05B11/1043—Sealing or attachment arrangements between pump and container
    • B05B11/1046—Sealing or attachment arrangements between pump and container the pump chamber being arranged substantially coaxially to the neck of the container
    • B05B11/1047—Sealing or attachment arrangements between pump and container the pump chamber being arranged substantially coaxially to the neck of the container the pump being preassembled as an independent unit before being mounted on the container
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D83/00—Containers or packages with special means for dispensing contents
    • B65D83/14—Containers or packages with special means for dispensing contents for delivery of liquid or semi-liquid contents by internal gaseous pressure, i.e. aerosol containers comprising propellant for a product delivered by a propellant
    • B65D83/44—Valves specially adapted therefor; Regulating devices
    • B65D83/52—Valves specially adapted therefor; Regulating devices for metering
    • B65D83/54—Metering valves ; Metering valve assemblies

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Endocrinology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dispersion Chemistry (AREA)
  • Obesity (AREA)
  • Diabetes (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Hematology (AREA)
  • Mechanical Engineering (AREA)
  • Otolaryngology (AREA)
  • Inorganic Chemistry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Containers And Packaging Bodies Having A Special Means To Remove Contents (AREA)
DE89912812T 1988-10-11 1989-10-09 Pharmazeutische zusammensetzungen mit gehalt an calcitonin zur intranasalen verabreichung und eine spray-einheit zur verabreichung derselben. Expired - Lifetime DE68912341T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
IT8822257A IT1227174B (it) 1988-10-11 1988-10-11 Composizioni farmaceutiche a base di calcitonina, somministrabili per via intranasale.
IT8822548A IT1227472B (it) 1988-11-08 1988-11-08 Confezione spray per la somministrazione intranasale di calcitonina.
PCT/EP1989/001186 WO1990003796A1 (en) 1988-10-11 1989-10-09 Pharmaceutical compositions comprising calcitonin for intranasal administration and a spray unit for the administration of the same

Publications (2)

Publication Number Publication Date
DE68912341D1 true DE68912341D1 (de) 1994-02-24
DE68912341T2 DE68912341T2 (de) 1994-05-05

Family

ID=26328146

Family Applications (1)

Application Number Title Priority Date Filing Date
DE89912812T Expired - Lifetime DE68912341T2 (de) 1988-10-11 1989-10-09 Pharmazeutische zusammensetzungen mit gehalt an calcitonin zur intranasalen verabreichung und eine spray-einheit zur verabreichung derselben.

Country Status (19)

Country Link
EP (2) EP0438531B1 (de)
JP (2) JPH0649658B2 (de)
KR (1) KR0152065B1 (de)
AU (1) AU632520B2 (de)
BR (1) BR8907708A (de)
CA (1) CA2000336C (de)
DE (1) DE68912341T2 (de)
DK (1) DK64291D0 (de)
ES (1) ES2053905T3 (de)
FI (1) FI95201C (de)
GR (1) GR3007420T3 (de)
HU (1) HU212495B (de)
IE (1) IE62327B1 (de)
IL (2) IL91856A0 (de)
NO (1) NO301522B1 (de)
NZ (1) NZ230965A (de)
RO (1) RO113301B1 (de)
RU (1) RU2097064C1 (de)
WO (1) WO1990003796A1 (de)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5026825A (en) * 1988-09-08 1991-06-25 Rhone-Poulenc Rorer Pharmaceuticals Inc. Intranasal calcitonin formulations
ES2067624T3 (es) * 1989-11-16 1995-04-01 Ph & T S R L Un procedimiento de preparacion de una composicion farmaceutica liquida para administracion nasal.
IT1242019B (it) * 1990-11-20 1994-02-02 Ripari Gero Ist Farm Biolog Composizioni farmaceutiche acquose a base di calcitonina, da somministrarsi per via nasale.
IT1282374B1 (it) * 1996-01-31 1998-03-20 Therapicon Srl Composizioni farmaceutiche parenterali a base di calcitonine sintetiche a ph controllato con basso indice di dolorosita'
DE19731472C2 (de) * 1997-07-22 2000-05-25 Gerhard Zellner Nasenspray-Flüssigkeit
IT1294191B1 (it) * 1997-09-05 1999-03-22 Alfa Wassermann Spa Composizioni farmaceutiche contenenti calcitonina in un dosatore spray per somministrazione intranasale.
SE9901658D0 (sv) * 1999-05-06 1999-05-06 Astra Ab New formulation
US6644305B2 (en) 2000-04-14 2003-11-11 Trudell Medical International Nasal inhaler
ATE401105T1 (de) * 2002-09-03 2008-08-15 Pharmacure Health Care Ab Nasensprays
EP2222411B1 (de) 2007-11-29 2013-10-09 Glaxo Group Limited Spendevorrichtung
GB2464282A (en) * 2008-10-08 2010-04-14 Archimedes Dev Ltd A device for administering a dose of opioid analgesic
CN103339034B (zh) 2011-02-04 2015-11-25 阿基米德开发有限公司 改进的容器
DE102011082420B4 (de) * 2011-09-09 2021-02-04 Aptar Radolfzell Gmbh Flüssigkeitsspender und Austragskopf für einen Flüssigkeitsspender

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA758010B (en) * 1975-11-14 1977-08-31 Syntex Inc Nasal spray adapter
CY1490A (en) * 1982-02-01 1990-02-16 Sandoz Ltd Improvements in or relating to nasal pharmaceutical compositions
BE897904A (fr) * 1982-10-05 1984-04-04 Sandoz Sa Nouvelles compositions galeniques a base de calcitonine
FR2561565B1 (fr) * 1984-03-23 1986-08-01 Norlac Plastiques Sa Couteau electrique destine notamment a l'ouverture des huitres
GB8407907D0 (en) * 1984-03-27 1984-05-02 Sandoz Ltd Organic compounds
JPS61118325A (ja) * 1984-11-12 1986-06-05 Yamanouchi Pharmaceut Co Ltd 塩基性および／または中性アミノ酸を含有するカルシトニン経鼻剤
JPS61126034A (ja) * 1984-11-26 1986-06-13 Yamanouchi Pharmaceut Co Ltd アルド−スを含有するカルシトニン経鼻剤
JPS61194034A (ja) * 1985-02-25 1986-08-28 Teijin Ltd 経鼻投与用粉末状組成物
JPS6310735A (ja) * 1986-07-02 1988-01-18 Yamanouchi Pharmaceut Co Ltd カルシトニン経鼻剤
JPS6339822A (ja) * 1986-08-04 1988-02-20 Yamanouchi Pharmaceut Co Ltd カルシトニン経鼻剤

Also Published As

Publication number Publication date
WO1990003796A1 (en) 1990-04-19
HU212495B (en) 1996-07-29
EP0363876A1 (de) 1990-04-18
HU896876D0 (en) 1991-07-29
KR0152065B1 (ko) 1998-10-15
IE62327B1 (en) 1995-01-25
JPH0649658B2 (ja) 1994-06-29
HUT63577A (en) 1993-09-28
NO301522B1 (no) 1997-11-10
JPH03505213A (ja) 1991-11-14
DK64291A (da) 1991-04-10
GR3007420T3 (de) 1993-07-30
IE893259L (en) 1990-04-11
DE68912341T2 (de) 1994-05-05
FI95201C (fi) 1996-01-10
CA2000336C (en) 2000-10-03
EP0438531A1 (de) 1991-07-31
EP0363876B1 (de) 1992-12-23
ES2053905T3 (es) 1994-08-01
RU2097064C1 (ru) 1997-11-27
NO911395D0 (no) 1991-04-10
JPH0796034A (ja) 1995-04-11
IL91856A0 (en) 1990-06-10
AU632520B2 (en) 1993-01-07
IL91931A (en) 1995-03-15
IL91931A0 (en) 1990-06-10
CA2000336A1 (en) 1990-04-11
EP0438531B1 (de) 1994-01-12
KR900701306A (ko) 1990-12-01
FI95201B (fi) 1995-09-29
DK64291D0 (da) 1991-04-10
NZ230965A (en) 1992-04-28
FI911722A0 (fi) 1991-04-10
NO911395L (no) 1991-04-10
RO113301B1 (ro) 1998-06-30
AU4622589A (en) 1990-05-01
BR8907708A (pt) 1991-07-30

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: ALFA WASSERMANN S.P.A., ALANNO SCALO, PESCARA, IT