DE60308994T2 - Verfahren zur extraktion, reinigung und enzymatischen veränderung von soja 7s globulin alpha' untereinheit zur verwendung als hypocholesterol-mischer-wirkstoff - Google Patents

Verfahren zur extraktion, reinigung und enzymatischen veränderung von soja 7s globulin alpha' untereinheit zur verwendung als hypocholesterol-mischer-wirkstoff Download PDF

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Publication number
DE60308994T2
DE60308994T2 DE60308994T DE60308994T DE60308994T2 DE 60308994 T2 DE60308994 T2 DE 60308994T2 DE 60308994 T DE60308994 T DE 60308994T DE 60308994 T DE60308994 T DE 60308994T DE 60308994 T2 DE60308994 T2 DE 60308994T2
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DE
Germany
Prior art keywords
subunit
conglycinin
mac
treatment
extraction
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60308994T
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German (de)
English (en)
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DE60308994D1 (de
Inventor
Marcello Duranti
Paolo Morazzoni
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Indena SpA
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Indena SpA
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Publication of DE60308994D1 publication Critical patent/DE60308994D1/de
Publication of DE60308994T2 publication Critical patent/DE60308994T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/168—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from plants
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23J—PROTEIN COMPOSITIONS FOR FOODSTUFFS; WORKING-UP PROTEINS FOR FOODSTUFFS; PHOSPHATIDE COMPOSITIONS FOR FOODSTUFFS
    • A23J1/00—Obtaining protein compositions for foodstuffs; Bulk opening of eggs and separation of yolks from whites
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23J—PROTEIN COMPOSITIONS FOR FOODSTUFFS; WORKING-UP PROTEINS FOR FOODSTUFFS; PHOSPHATIDE COMPOSITIONS FOR FOODSTUFFS
    • A23J1/00—Obtaining protein compositions for foodstuffs; Bulk opening of eggs and separation of yolks from whites
    • A23J1/14—Obtaining protein compositions for foodstuffs; Bulk opening of eggs and separation of yolks from whites from leguminous or other vegetable seeds; from press-cake or oil-bearing seeds
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23J—PROTEIN COMPOSITIONS FOR FOODSTUFFS; WORKING-UP PROTEINS FOR FOODSTUFFS; PHOSPHATIDE COMPOSITIONS FOR FOODSTUFFS
    • A23J3/00—Working-up of proteins for foodstuffs
    • A23J3/14—Vegetable proteins
    • A23J3/16—Vegetable proteins from soybean
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/17—Amino acids, peptides or proteins
    • A23L33/185—Vegetable proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/02—Nutrients, e.g. vitamins, minerals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
    • C12P7/04—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic
    • C12P7/06—Ethanol, i.e. non-beverage
    • C—CHEMISTRY; METALLURGY
    • C13—SUGAR INDUSTRY
    • C13K—SACCHARIDES OBTAINED FROM NATURAL SOURCES OR BY HYDROLYSIS OF NATURALLY OCCURRING DISACCHARIDES, OLIGOSACCHARIDES OR POLYSACCHARIDES
    • C13K1/00—Glucose; Glucose-containing syrups
    • C13K1/06—Glucose; Glucose-containing syrups obtained by saccharification of starch or raw materials containing starch
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02E—REDUCTION OF GREENHOUSE GAS [GHG] EMISSIONS, RELATED TO ENERGY GENERATION, TRANSMISSION OR DISTRIBUTION
    • Y02E50/00—Technologies for the production of fuel of non-fossil origin
    • Y02E50/10—Biofuels, e.g. bio-diesel

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  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Polymers & Plastics (AREA)
  • Food Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Nutrition Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Botany (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Mycology (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Emergency Medicine (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Steroid Compounds (AREA)
DE60308994T 2002-01-29 2003-01-27 Verfahren zur extraktion, reinigung und enzymatischen veränderung von soja 7s globulin alpha' untereinheit zur verwendung als hypocholesterol-mischer-wirkstoff Expired - Lifetime DE60308994T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
IT2002MI000147A ITMI20020147A1 (it) 2002-01-29 2002-01-29 Estrazione purificazione e modificazione di polipeptidi da seme di soia
ITMI20020147 2002-01-29
PCT/EP2003/000798 WO2003063608A1 (en) 2002-01-29 2003-01-27 A process for the extraction, purification and enzymatic modification of soy 7s globulin alpha' subunit for use as hypocholesterolemizing agent

Publications (2)

Publication Number Publication Date
DE60308994D1 DE60308994D1 (de) 2006-11-23
DE60308994T2 true DE60308994T2 (de) 2007-06-14

Family

ID=11449014

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60308994T Expired - Lifetime DE60308994T2 (de) 2002-01-29 2003-01-27 Verfahren zur extraktion, reinigung und enzymatischen veränderung von soja 7s globulin alpha' untereinheit zur verwendung als hypocholesterol-mischer-wirkstoff

Country Status (20)

Country Link
US (3) US7465467B2 (https=)
EP (1) EP1469741B1 (https=)
JP (1) JP4522706B2 (https=)
KR (1) KR100991641B1 (https=)
CN (1) CN100558243C (https=)
AT (1) ATE341943T1 (https=)
AU (1) AU2003208346B8 (https=)
CA (1) CA2474106C (https=)
CY (1) CY1107514T1 (https=)
DE (1) DE60308994T2 (https=)
DK (1) DK1469741T3 (https=)
ES (1) ES2274208T3 (https=)
IL (1) IL163225A (https=)
IT (1) ITMI20020147A1 (https=)
NO (1) NO327156B1 (https=)
PL (1) PL209342B1 (https=)
PT (1) PT1469741E (https=)
RU (1) RU2300898C2 (https=)
SG (1) SG152048A1 (https=)
WO (1) WO2003063608A1 (https=)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6171640B1 (en) * 1997-04-04 2001-01-09 Monsanto Company High beta-conglycinin products and their use
DE60316833T2 (de) * 2002-11-12 2008-07-17 Fuji Oil Co., Ltd. Fraktioniertes sojabohnenprotein und herstellungsverfahren dafür
WO2005055735A1 (ja) * 2003-12-11 2005-06-23 Fuji Oil Company, Limited 改良大豆７ｓたん白及びその製造法
JP5382840B2 (ja) * 2005-08-23 2014-01-08 特定非営利活動法人プライメイト・アゴラ サルモデルで薬効が確認された骨粗鬆症の予防又は治療剤
RU2011132127A (ru) * 2008-12-31 2013-02-10 СОЛАЕ, ЭлЭлСи Композиции белкового гидролизата
EP2264054A1 (en) * 2009-06-17 2010-12-22 Indena S.p.A. Cloning, yeast expression, purification and biological activity of a truncated form of the soybean 7S globulin alfa ' subunit involved in Hep G2 cell cholesterol homeostasis
DK2264055T3 (da) * 2009-06-17 2014-04-07 Indena Spa Kloning, gærekspression, oprensning og biologisk aktivitet af forlængelsesregionen af sojabønne-7S-globulin-alfa'-underenheden involveret i Hep-G2-cellekolesterolhomøostase
CN101904406B (zh) * 2010-07-02 2012-07-25 山西大学 一种葵花籽多肽的制备方法和用途
CN104163767B (zh) * 2014-07-25 2017-01-18 湖北泓肽生物科技有限公司 一种氨基酸和多肽水溶性物质的纯化方法
CN114874301A (zh) * 2022-05-10 2022-08-09 吉林农业大学 不同亚基组成β-伴大豆球蛋白的制备方法及应用

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4409248A (en) * 1981-08-10 1983-10-11 A. E. Staley Manufacturing Company Heat-gelling and foam-stabilizing enzymatically modified vegetable isolates
JPH06197788A (ja) * 1993-01-06 1994-07-19 Fuji Oil Co Ltd 蛋白質の製造法
EP0797928B1 (en) * 1996-03-28 1999-11-10 Fuji Oil Co., Ltd. Process for producing a soy protein hydrolysate
WO1997047731A2 (en) * 1996-06-14 1997-12-18 E.I. Du Pont De Nemours And Company Suppression of specific classes of soybean seed protein genes
US6171640B1 (en) * 1997-04-04 2001-01-09 Monsanto Company High beta-conglycinin products and their use
US6365802B2 (en) * 1998-08-14 2002-04-02 Calgene Llc Methods for increasing stearate content in soybean oil
FR2784029B1 (fr) * 1998-10-05 2001-01-05 Pharmascience Lab Methode de prevention et/ou de traitement cosmetique des vergetures de la peau et utilisation en dermatologie
MXPA01010488A (es) * 1999-04-15 2003-07-21 Calgene Llc Secuencias de acidos nucleicos para proteinas que intervienen en sintesis isoprenoide.
CA2274414A1 (en) 1999-06-11 2000-12-11 Universite Laval Dietary fish protein for use in restoring normal insulin function insulin-resistant individuals
AUPQ877300A0 (en) 2000-07-13 2000-08-03 Johnson & Johnson Pacific Pty Limited Topical treatment of skin
BRPI0309421B8 (pt) * 2002-04-18 2021-05-25 Monsanto Technology Llc método de preparar um gênero alimentício e composição para tratar ou prevenir hipercolesterolemia
ATE446969T1 (de) * 2003-08-20 2009-11-15 Seikagaku Kogyo Co Ltd Stabilisierungsmittel für enzyme
MX2007008496A (es) * 2005-01-14 2007-09-14 Solae Llc Proteina de soya para formula infantil.

Also Published As

Publication number Publication date
CY1107514T1 (el) 2013-03-13
KR100991641B1 (ko) 2010-11-04
US7901718B2 (en) 2011-03-08
IL163225A (en) 2007-06-17
CN1622760A (zh) 2005-06-01
PT1469741E (pt) 2007-01-31
US7465467B2 (en) 2008-12-16
WO2003063608A1 (en) 2003-08-07
AU2003208346A2 (en) 2003-09-02
CA2474106A1 (en) 2003-08-07
NO20043186L (no) 2004-07-26
ITMI20020147A1 (it) 2003-07-29
US20110118182A1 (en) 2011-05-19
PL370294A1 (en) 2005-05-16
US20050164337A1 (en) 2005-07-28
US20080261885A1 (en) 2008-10-23
AU2003208346B2 (en) 2008-03-06
NO327156B1 (no) 2009-05-04
SG152048A1 (en) 2009-05-29
JP4522706B2 (ja) 2010-08-11
CA2474106C (en) 2011-11-22
JP2005516043A (ja) 2005-06-02
RU2004123201A (ru) 2005-10-27
RU2300898C2 (ru) 2007-06-20
AU2003208346B8 (en) 2008-07-10
KR20040077786A (ko) 2004-09-06
ITMI20020147A0 (it) 2002-01-29
DE60308994D1 (de) 2006-11-23
EP1469741A1 (en) 2004-10-27
ES2274208T3 (es) 2007-05-16
ATE341943T1 (de) 2006-11-15
HK1073590A1 (zh) 2005-10-14
US8257758B2 (en) 2012-09-04
PL209342B1 (pl) 2011-08-31
DK1469741T3 (da) 2007-02-19
CN100558243C (zh) 2009-11-11
EP1469741B1 (en) 2006-10-11

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Representative=s name: MAIWALD PATENTANWALTSGESELLSCHAFT MBH, 80335 MUENC