DE60223718T2 - Verwendung von norepinephrin wiederaufnahmehemmern zur behandlung von kognitiven störungen - Google Patents

Verwendung von norepinephrin wiederaufnahmehemmern zur behandlung von kognitiven störungen Download PDF

Info

Publication number
DE60223718T2
DE60223718T2 DE60223718T DE60223718T DE60223718T2 DE 60223718 T2 DE60223718 T2 DE 60223718T2 DE 60223718 T DE60223718 T DE 60223718T DE 60223718 T DE60223718 T DE 60223718T DE 60223718 T2 DE60223718 T2 DE 60223718T2
Authority
DE
Germany
Prior art keywords
dementia
use according
disease
atomoxetine
methyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE60223718T
Other languages
German (de)
English (en)
Other versions
DE60223718D1 (de
Inventor
Franklin Porter Brownsburg Bymaster
Donald Richard Indianapolis GEHLERT
David Lee Whitestown MCKINZIE
Charles Renkin Indianapolis YANG
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Eli Lilly and Co
Original Assignee
Eli Lilly and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eli Lilly and Co filed Critical Eli Lilly and Co
Publication of DE60223718D1 publication Critical patent/DE60223718D1/de
Application granted granted Critical
Publication of DE60223718T2 publication Critical patent/DE60223718T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/138—Aryloxyalkylamines, e.g. propranolol, tamoxifen, phenoxybenzamine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/5375—1,4-Oxazines, e.g. morpholine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Psychiatry (AREA)
  • Emergency Medicine (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
DE60223718T 2001-12-11 2002-11-27 Verwendung von norepinephrin wiederaufnahmehemmern zur behandlung von kognitiven störungen Expired - Fee Related DE60223718T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US33917401P 2001-12-11 2001-12-11
US339174P 2001-12-11
PCT/US2002/036132 WO2003049724A1 (en) 2001-12-11 2002-11-27 Use of norepinephrine reuptake inhibitors for the treatment of cognitive failure

Publications (2)

Publication Number Publication Date
DE60223718D1 DE60223718D1 (de) 2008-01-03
DE60223718T2 true DE60223718T2 (de) 2008-10-30

Family

ID=23327833

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60223718T Expired - Fee Related DE60223718T2 (de) 2001-12-11 2002-11-27 Verwendung von norepinephrin wiederaufnahmehemmern zur behandlung von kognitiven störungen

Country Status (26)

Country Link
US (1) US20050009925A1 (https=)
EP (1) EP1458368B1 (https=)
JP (1) JP2005517647A (https=)
KR (1) KR20040066895A (https=)
CN (1) CN1713900A (https=)
AU (1) AU2002352625A1 (https=)
BR (1) BR0213581A (https=)
CA (1) CA2467802A1 (https=)
CO (1) CO5590907A2 (https=)
CZ (1) CZ2004709A3 (https=)
DE (1) DE60223718T2 (https=)
EA (1) EA200400793A1 (https=)
EC (1) ECSP045145A (https=)
ES (1) ES2295435T3 (https=)
HR (1) HRPK20040528B3 (https=)
HU (1) HUP0402619A3 (https=)
IL (1) IL161989A0 (https=)
MX (1) MXPA04005716A (https=)
MY (1) MY136367A (https=)
NO (1) NO20042904L (https=)
NZ (1) NZ532065A (https=)
PL (1) PL369311A1 (https=)
SK (1) SK2442004A3 (https=)
TW (1) TW200300672A (https=)
WO (1) WO2003049724A1 (https=)
ZA (1) ZA200404274B (https=)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1530476A1 (en) * 2002-08-14 2005-05-18 Pharmacia & Upjohn Company LLC Use of reboxetine for the treatment of hot flashes
EP1708717B1 (en) * 2003-07-28 2011-10-05 Leslie Joe Dunaway Atomoxetine for treatment of allergic rhinitis and asthma
EP1660064A2 (en) * 2003-08-27 2006-05-31 Eli Lilly And Company Treatment of learning disabilities and motor skills disorder with norepinephrine reuptake inhibitors
EP1729754B1 (en) * 2003-12-12 2008-07-02 Eli Lilly And Company Selective norepinephrine reuptake inhibitors for the treatment of hot flashes
BRPI0510453A (pt) * 2004-04-30 2007-10-30 Warner Lambert Co composto substituìdos com morfolina para o tratamento de distúrbios do sistema nervoso central
US7439399B2 (en) * 2004-06-28 2008-10-21 Teva Pharmaceutical Fine Chemicals Processes for the preparation of atomoxetine hydrochloride
US8580776B2 (en) * 2007-07-10 2013-11-12 The Board Of Trustees Of The University Of Illinois Compositions and methods for treating neurodegenerating diseases
US20100069389A1 (en) * 2008-09-06 2010-03-18 Bionevia Pharmaceuticals, Inc. Novel forms of reboxetine
US20100317730A1 (en) * 2009-06-12 2010-12-16 Shaya Elias K Treatment for menopausal and perimenopausal vasomotor symptons
WO2011014475A2 (en) * 2009-07-31 2011-02-03 National Taiwan University Treating negative symptoms of schizophrenia associated with defective neuregulin 1
JP6126531B2 (ja) * 2011-10-03 2017-05-10 国立研究開発法人国立長寿医療研究センター タウ凝集阻害剤
US20140206667A1 (en) 2012-11-14 2014-07-24 Michela Gallagher Methods and compositions for treating schizophrenia
US9907799B2 (en) 2013-04-02 2018-03-06 The Doshisha Tau aggregation inhibitor

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4314081A (en) * 1974-01-10 1982-02-02 Eli Lilly And Company Arloxyphenylpropylamines
US5281624A (en) * 1991-09-27 1994-01-25 Eli Lilly And Company N-alkyl-3-phenyl-3-(2-substituted phenoxy) propylamines and pharmaceutical use thereof
US5658590A (en) * 1995-01-11 1997-08-19 Eli Lilly And Company Treatment of attention-deficit/hyperactivity disorder
US6465458B1 (en) * 1999-07-01 2002-10-15 Pharmacia & Upjohn Company Method of treating or preventing chronic pain with a highly selective norepinephrine reuptake inhibitor
AP2002002481A0 (en) * 1999-10-13 2002-06-30 Pfizer Prod Inc Biaryl ether derivatives useful as monoamine reuptake inhibitors.
AU2002243451A1 (en) * 2001-01-02 2002-07-16 Sention, Inc. Use of catecholamine reuptake inhibitors to enhance memory
JP2004517112A (ja) * 2001-01-02 2004-06-10 ファルマシア・アンド・アップジョン・カンパニー 新規薬物コンビネーション

Also Published As

Publication number Publication date
BR0213581A (pt) 2004-08-24
CA2467802A1 (en) 2003-06-19
DE60223718D1 (de) 2008-01-03
US20050009925A1 (en) 2005-01-13
ECSP045145A (es) 2004-07-23
KR20040066895A (ko) 2004-07-27
ZA200404274B (en) 2005-09-13
HRPK20040528B3 (en) 2006-03-31
CZ2004709A3 (cs) 2004-10-13
AU2002352625A1 (en) 2003-06-23
EP1458368A1 (en) 2004-09-22
HUP0402619A2 (hu) 2005-03-29
TW200300672A (en) 2003-06-16
JP2005517647A (ja) 2005-06-16
SK2442004A3 (en) 2004-12-01
MXPA04005716A (es) 2004-12-06
CO5590907A2 (es) 2005-12-30
WO2003049724A1 (en) 2003-06-19
NO20042904L (no) 2004-09-07
EP1458368B1 (en) 2007-11-21
ES2295435T3 (es) 2008-04-16
EA200400793A1 (ru) 2004-10-28
NZ532065A (en) 2007-03-30
HRP20040528A2 (en) 2004-10-31
IL161989A0 (en) 2005-11-20
CN1713900A (zh) 2005-12-28
PL369311A1 (en) 2005-04-18
HUP0402619A3 (en) 2008-04-28
MY136367A (en) 2008-09-30

Similar Documents

Publication Publication Date Title
DE69623141T2 (de) Verwendung von Tomoxetin zur Behandlung von Hyperaktivität mit Aufmerksamkeitsstörungen
DE60223718T2 (de) Verwendung von norepinephrin wiederaufnahmehemmern zur behandlung von kognitiven störungen
DE3782935T2 (de) Praeparat zur vorbeugung vor seekrankheit.
DE69507419T2 (de) Verwendung von einem Tetrahydropyridin- oder azabicyclischen Oxadiazol- oder -Thiadiazol-Verbindung zur Behandlung von Angstzuständen
DE69819891T2 (de) Spiro chinuclidin-derivate, ihre herstellung und verwendung
DE3855323T2 (de) Galenische 2-beta-Mimetik-Formen für die per- und sublinguale Verabreichung
DE69926804T2 (de) Vorrichtungen zur behandlung und diagnose des restless leg syndroms
DE4241013A1 (de) Verwendung von 2-Amino-6-n-propyl-amino-4,5,6,7-tetrahydrobenzothiazol als Arzneimittel mit antidepressiver Wirkung
DE3686108T2 (de) Verwendung von p-chlorophenoxyazetat von n,n-dimethylbiguanid zur behandlung von neuropathien und nervendegeneration.
CH668184A5 (de) Verwendung von acyloxyalkanoylcholinsalzen fuer die herstellung eines mittels zur besserung und therapie von neuropsychiatrischen symptomen, die die demenz begleiten.
EP2050435B1 (de) Hustenpräparat
DE602004009079T2 (de) Carbostyril-derivative zur beschleunigten speichelabsonderung
EP0826370A1 (de) Pharmazeutische Zubereitung, die 2-Phenyl-1,2-Benzoisoelenazol-3(2H)-one enthält, für die Behandlung der Alzheimer-Krankheit
EP1461042B1 (de) Verwendung von desoxypeganin zur behandlung der klinischen depression
DE60220825T2 (de) Verwendung von norepinephrinwiederaufnahmehemmern zur behandlung von ticks
DE3008993A1 (de) Pharmazeutische zubereitungen
DE60009315T2 (de) Verwendung von cyamemazin zur behandlung von entwöhnungserscheinungen der benzodiazepinbehandlung
DE69904206T2 (de) Verwendung von cetirizin zur vorbeugung von asthma eintritt
DE69516075T2 (de) Verwendung von einem azabicyclischen Oxadiazol- oder -Thiadiazol-Verbindung zur Behandlung von Angstzuständen
DD297557A5 (de) Verwendung von dopamin-autorezeptor-agonisten bei der behandlung von drogenabhaengigkeit
EP0493861B1 (de) Nicotinamid-adenin-dinukleodid enthaltendes Antidepressionsmittel
DE2461570C3 (de) Arzneimittel für die Behandlung bakterieller Infektionen der Augen und/oder der Ohren und Verfahren zu ihrer Herstellung
EP0358683A1 (de) Pharmazeutikum
DE10354893B4 (de) Verwendung von Desoxypeganin zur Behandlung schizophrener Psychosen
DE3432974A1 (de) Arzneimittel zur prophylaxe oder therapie der negativen shizophreniesymtome bei menschen

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8328 Change in the person/name/address of the agent

Representative=s name: KROHER, STROBEL RECHTS- UND PATENTANWAELTE, 80336

8339 Ceased/non-payment of the annual fee