EA200400793A1 - Применение ингибиторов обратного захвата норэпинефрина для лечения нарушения познавательной функции - Google Patents
Применение ингибиторов обратного захвата норэпинефрина для лечения нарушения познавательной функцииInfo
- Publication number
- EA200400793A1 EA200400793A1 EA200400793A EA200400793A EA200400793A1 EA 200400793 A1 EA200400793 A1 EA 200400793A1 EA 200400793 A EA200400793 A EA 200400793A EA 200400793 A EA200400793 A EA 200400793A EA 200400793 A1 EA200400793 A1 EA 200400793A1
- Authority
- EA
- Eurasian Patent Office
- Prior art keywords
- inhibitors
- norepinefrin
- application
- cognitive function
- reverse capture
- Prior art date
Links
- 230000003920 cognitive function Effects 0.000 title 1
- 239000003112 inhibitor Substances 0.000 title 1
- 208000028698 Cognitive impairment Diseases 0.000 abstract 2
- 208000010877 cognitive disease Diseases 0.000 abstract 2
- 206010012218 Delirium Diseases 0.000 abstract 1
- 206010012289 Dementia Diseases 0.000 abstract 1
- VHGCDTVCOLNTBX-QGZVFWFLSA-N atomoxetine Chemical compound O([C@H](CCNC)C=1C=CC=CC=1)C1=CC=CC=C1C VHGCDTVCOLNTBX-QGZVFWFLSA-N 0.000 abstract 1
- 229960002430 atomoxetine Drugs 0.000 abstract 1
- YNRZXCYIUVELOE-UHFFFAOYSA-N n-phenoxy-3-phenylpropan-1-amine Chemical class C=1C=CC=CC=1CCCNOC1=CC=CC=C1 YNRZXCYIUVELOE-UHFFFAOYSA-N 0.000 abstract 1
- 239000002767 noradrenalin uptake inhibitor Substances 0.000 abstract 1
- CBQGYUDMJHNJBX-RTBURBONSA-N reboxetine Chemical compound CCOC1=CC=CC=C1O[C@H](C=1C=CC=CC=1)[C@@H]1OCCNC1 CBQGYUDMJHNJBX-RTBURBONSA-N 0.000 abstract 1
- 229960003770 reboxetine Drugs 0.000 abstract 1
- 201000000980 schizophrenia Diseases 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/138—Aryloxyalkylamines, e.g. propranolol, tamoxifen, phenoxybenzamine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/5375—1,4-Oxazines, e.g. morpholine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Emergency Medicine (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US33917401P | 2001-12-11 | 2001-12-11 | |
| PCT/US2002/036132 WO2003049724A1 (en) | 2001-12-11 | 2002-11-27 | Use of norepinephrine reuptake inhibitors for the treatment of cognitive failure |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| EA200400793A1 true EA200400793A1 (ru) | 2004-10-28 |
Family
ID=23327833
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EA200400793A EA200400793A1 (ru) | 2001-12-11 | 2002-11-27 | Применение ингибиторов обратного захвата норэпинефрина для лечения нарушения познавательной функции |
Country Status (26)
| Country | Link |
|---|---|
| US (1) | US20050009925A1 (https=) |
| EP (1) | EP1458368B1 (https=) |
| JP (1) | JP2005517647A (https=) |
| KR (1) | KR20040066895A (https=) |
| CN (1) | CN1713900A (https=) |
| AU (1) | AU2002352625A1 (https=) |
| BR (1) | BR0213581A (https=) |
| CA (1) | CA2467802A1 (https=) |
| CO (1) | CO5590907A2 (https=) |
| CZ (1) | CZ2004709A3 (https=) |
| DE (1) | DE60223718T2 (https=) |
| EA (1) | EA200400793A1 (https=) |
| EC (1) | ECSP045145A (https=) |
| ES (1) | ES2295435T3 (https=) |
| HR (1) | HRPK20040528B3 (https=) |
| HU (1) | HUP0402619A3 (https=) |
| IL (1) | IL161989A0 (https=) |
| MX (1) | MXPA04005716A (https=) |
| MY (1) | MY136367A (https=) |
| NO (1) | NO20042904L (https=) |
| NZ (1) | NZ532065A (https=) |
| PL (1) | PL369311A1 (https=) |
| SK (1) | SK2442004A3 (https=) |
| TW (1) | TW200300672A (https=) |
| WO (1) | WO2003049724A1 (https=) |
| ZA (1) | ZA200404274B (https=) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20050049476A (ko) * | 2002-08-14 | 2005-05-25 | 파마시아 앤드 업존 캄파니 엘엘씨 | 홍조를 치료하기 위한 레복세틴의 용도 |
| ATE526954T1 (de) * | 2003-07-28 | 2011-10-15 | Leslie Joe Dunaway | Atomoxetin zur behandlung von allergischer rhinitis und asthma |
| CA2530014A1 (en) * | 2003-08-27 | 2005-03-10 | Eli Lilly And Company | Treatment of learning disabilities and motor skills disorder with norepinephrine reuptake inhibitors |
| KR20060121178A (ko) * | 2003-12-12 | 2006-11-28 | 일라이 릴리 앤드 캄파니 | 일과성 전신 열감, 충동 조절 장애 및 일반적인 의학상태로 인한 인격 변화 치료용 선택적 노르에피네프린재흡수 억제제 |
| JP4185154B2 (ja) * | 2004-04-30 | 2008-11-26 | ワーナー−ランバート カンパニー リミテッド ライアビリティー カンパニー | 中枢神経系障害治療用の置換モルホリン化合物 |
| US7439399B2 (en) * | 2004-06-28 | 2008-10-21 | Teva Pharmaceutical Fine Chemicals | Processes for the preparation of atomoxetine hydrochloride |
| US8580776B2 (en) * | 2007-07-10 | 2013-11-12 | The Board Of Trustees Of The University Of Illinois | Compositions and methods for treating neurodegenerating diseases |
| US20100069389A1 (en) * | 2008-09-06 | 2010-03-18 | Bionevia Pharmaceuticals, Inc. | Novel forms of reboxetine |
| US20100317731A1 (en) * | 2009-06-12 | 2010-12-16 | Shaya Elias K | Hyperhidrosis treatment |
| TW201107485A (en) * | 2009-07-31 | 2011-03-01 | Univ Nat Taiwan | Treating negative symptoms of schizophrenia associated with defective neuregulin 1 (NRG1) |
| EP2764863B1 (en) * | 2011-10-03 | 2020-03-11 | National Center for Geriatrics and Gerontology | Tau aggregation inhibitor |
| US20140206667A1 (en) | 2012-11-14 | 2014-07-24 | Michela Gallagher | Methods and compositions for treating schizophrenia |
| EP2962687B1 (en) | 2013-04-02 | 2019-06-05 | The Doshisha | Tau aggregation inhibitor |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4314081A (en) * | 1974-01-10 | 1982-02-02 | Eli Lilly And Company | Arloxyphenylpropylamines |
| US5281624A (en) * | 1991-09-27 | 1994-01-25 | Eli Lilly And Company | N-alkyl-3-phenyl-3-(2-substituted phenoxy) propylamines and pharmaceutical use thereof |
| US5658590A (en) * | 1995-01-11 | 1997-08-19 | Eli Lilly And Company | Treatment of attention-deficit/hyperactivity disorder |
| DE60022692T2 (de) * | 1999-07-01 | 2006-06-22 | Pharmacia & Upjohn Co. Llc, Kalamazoo | (S,S)-Reboxetin zur Behandlung von Migränekopfschmerzen |
| WO2001027068A1 (en) * | 1999-10-13 | 2001-04-19 | Pfizer Products Inc. | Biaryl ether derivatives useful as monoamine reuptake inhibitors |
| CA2431041A1 (en) * | 2001-01-02 | 2002-07-11 | Pharmacia & Upjohn Company | New drug combinations of norepinehrine reuptake inhibitors and neuroleptic agents |
| WO2002053104A2 (en) * | 2001-01-02 | 2002-07-11 | Sention, Inc. | Use of catecholamine reuptake inhibitors to enhance memory |
-
2002
- 2002-11-27 DE DE60223718T patent/DE60223718T2/de not_active Expired - Fee Related
- 2002-11-27 CA CA002467802A patent/CA2467802A1/en not_active Abandoned
- 2002-11-27 HR HR20040528A patent/HRPK20040528B3/xx not_active IP Right Cessation
- 2002-11-27 CZ CZ2004709A patent/CZ2004709A3/cs unknown
- 2002-11-27 KR KR10-2004-7009039A patent/KR20040066895A/ko not_active Withdrawn
- 2002-11-27 MX MXPA04005716A patent/MXPA04005716A/es not_active Application Discontinuation
- 2002-11-27 EP EP02789574A patent/EP1458368B1/en not_active Expired - Lifetime
- 2002-11-27 AU AU2002352625A patent/AU2002352625A1/en not_active Abandoned
- 2002-11-27 BR BR0213581-7A patent/BR0213581A/pt not_active IP Right Cessation
- 2002-11-27 US US10/496,765 patent/US20050009925A1/en not_active Abandoned
- 2002-11-27 ES ES02789574T patent/ES2295435T3/es not_active Expired - Lifetime
- 2002-11-27 SK SK244-2004A patent/SK2442004A3/sk not_active Application Discontinuation
- 2002-11-27 WO PCT/US2002/036132 patent/WO2003049724A1/en not_active Ceased
- 2002-11-27 IL IL16198902A patent/IL161989A0/xx unknown
- 2002-11-27 HU HU0402619A patent/HUP0402619A3/hu unknown
- 2002-11-27 PL PL02369311A patent/PL369311A1/xx unknown
- 2002-11-27 CN CNA028247264A patent/CN1713900A/zh active Pending
- 2002-11-27 NZ NZ532065A patent/NZ532065A/en unknown
- 2002-11-27 JP JP2003550773A patent/JP2005517647A/ja active Pending
- 2002-11-27 EA EA200400793A patent/EA200400793A1/ru unknown
- 2002-12-05 MY MYPI20024591A patent/MY136367A/en unknown
- 2002-12-05 TW TW091135296A patent/TW200300672A/zh unknown
-
2004
- 2004-05-31 ZA ZA200404274A patent/ZA200404274B/en unknown
- 2004-06-09 CO CO04054292A patent/CO5590907A2/es not_active Application Discontinuation
- 2004-06-09 EC EC2004005145A patent/ECSP045145A/es unknown
- 2004-07-09 NO NO20042904A patent/NO20042904L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| CA2467802A1 (en) | 2003-06-19 |
| CN1713900A (zh) | 2005-12-28 |
| ECSP045145A (es) | 2004-07-23 |
| EP1458368A1 (en) | 2004-09-22 |
| TW200300672A (en) | 2003-06-16 |
| HUP0402619A3 (en) | 2008-04-28 |
| US20050009925A1 (en) | 2005-01-13 |
| NO20042904L (no) | 2004-09-07 |
| HUP0402619A2 (hu) | 2005-03-29 |
| BR0213581A (pt) | 2004-08-24 |
| IL161989A0 (en) | 2005-11-20 |
| ZA200404274B (en) | 2005-09-13 |
| DE60223718T2 (de) | 2008-10-30 |
| PL369311A1 (en) | 2005-04-18 |
| NZ532065A (en) | 2007-03-30 |
| MXPA04005716A (es) | 2004-12-06 |
| KR20040066895A (ko) | 2004-07-27 |
| ES2295435T3 (es) | 2008-04-16 |
| DE60223718D1 (de) | 2008-01-03 |
| JP2005517647A (ja) | 2005-06-16 |
| HRPK20040528B3 (en) | 2006-03-31 |
| CZ2004709A3 (cs) | 2004-10-13 |
| CO5590907A2 (es) | 2005-12-30 |
| EP1458368B1 (en) | 2007-11-21 |
| HRP20040528A2 (en) | 2004-10-31 |
| WO2003049724A1 (en) | 2003-06-19 |
| AU2002352625A1 (en) | 2003-06-23 |
| SK2442004A3 (en) | 2004-12-01 |
| MY136367A (en) | 2008-09-30 |
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