HUP0402619A2 - Norepinefrin re-uptake inhibitorok alkalmazása a megértési nehézségek kezelésére használható gyógyszer előállítására - Google Patents
Norepinefrin re-uptake inhibitorok alkalmazása a megértési nehézségek kezelésére használható gyógyszer előállításáraInfo
- Publication number
- HUP0402619A2 HUP0402619A2 HU0402619A HUP0402619A HUP0402619A2 HU P0402619 A2 HUP0402619 A2 HU P0402619A2 HU 0402619 A HU0402619 A HU 0402619A HU P0402619 A HUP0402619 A HU P0402619A HU P0402619 A2 HUP0402619 A2 HU P0402619A2
- Authority
- HU
- Hungary
- Prior art keywords
- medicament
- preparation
- treatment
- reuptake inhibitors
- norepinephrine reuptake
- Prior art date
Links
- 239000003814 drug Substances 0.000 title abstract 2
- 230000001149 cognitive effect Effects 0.000 title 1
- 239000002767 noradrenalin uptake inhibitor Substances 0.000 title 1
- 229940127221 norepinephrine reuptake inhibitor Drugs 0.000 title 1
- 208000028698 Cognitive impairment Diseases 0.000 abstract 1
- 206010012218 Delirium Diseases 0.000 abstract 1
- 208000010513 Stupor Diseases 0.000 abstract 1
- VHGCDTVCOLNTBX-QGZVFWFLSA-N atomoxetine Chemical compound O([C@H](CCNC)C=1C=CC=CC=1)C1=CC=CC=C1C VHGCDTVCOLNTBX-QGZVFWFLSA-N 0.000 abstract 1
- 229960002430 atomoxetine Drugs 0.000 abstract 1
- 208000010877 cognitive disease Diseases 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 239000003112 inhibitor Substances 0.000 abstract 1
- YNRZXCYIUVELOE-UHFFFAOYSA-N n-phenoxy-3-phenylpropan-1-amine Chemical class C=1C=CC=CC=1CCCNOC1=CC=CC=C1 YNRZXCYIUVELOE-UHFFFAOYSA-N 0.000 abstract 1
- 230000000966 norepinephrine reuptake Effects 0.000 abstract 1
- CBQGYUDMJHNJBX-RTBURBONSA-N reboxetine Chemical compound CCOC1=CC=CC=C1O[C@H](C=1C=CC=CC=1)[C@@H]1OCCNC1 CBQGYUDMJHNJBX-RTBURBONSA-N 0.000 abstract 1
- 229960003770 reboxetine Drugs 0.000 abstract 1
- 201000000980 schizophrenia Diseases 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/5375—1,4-Oxazines, e.g. morpholine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/138—Aryloxyalkylamines, e.g. propranolol, tamoxifen, phenoxybenzamine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurosurgery (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Emergency Medicine (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Abstract
A találmány tárgya szelektív norepinefrin re-uptake inhibitorok, főlegatomoxetine reboxetine és 2-alkiltio-helyettesített fenoxifenilpropilaminok alkalmazása megértési nehézség például az elbutulás,delírium és skizofrénia által okozott megértési nehézség kezelésérehasználható gyógyszer előállítására. Ó
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US33917401P | 2001-12-11 | 2001-12-11 | |
PCT/US2002/036132 WO2003049724A1 (en) | 2001-12-11 | 2002-11-27 | Use of norepinephrine reuptake inhibitors for the treatment of cognitive failure |
Publications (2)
Publication Number | Publication Date |
---|---|
HUP0402619A2 true HUP0402619A2 (hu) | 2005-03-29 |
HUP0402619A3 HUP0402619A3 (en) | 2008-04-28 |
Family
ID=23327833
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HU0402619A HUP0402619A3 (en) | 2001-12-11 | 2002-11-27 | Use of norepinephrine reuptake inhibitors for the preparation of a medicament for treatment of cognitive failure |
Country Status (26)
Country | Link |
---|---|
US (1) | US20050009925A1 (hu) |
EP (1) | EP1458368B1 (hu) |
JP (1) | JP2005517647A (hu) |
KR (1) | KR20040066895A (hu) |
CN (1) | CN1713900A (hu) |
AU (1) | AU2002352625A1 (hu) |
BR (1) | BR0213581A (hu) |
CA (1) | CA2467802A1 (hu) |
CO (1) | CO5590907A2 (hu) |
CZ (1) | CZ2004709A3 (hu) |
DE (1) | DE60223718T2 (hu) |
EA (1) | EA200400793A1 (hu) |
EC (1) | ECSP045145A (hu) |
ES (1) | ES2295435T3 (hu) |
HR (1) | HRPK20040528B3 (hu) |
HU (1) | HUP0402619A3 (hu) |
IL (1) | IL161989A0 (hu) |
MX (1) | MXPA04005716A (hu) |
MY (1) | MY136367A (hu) |
NO (1) | NO20042904L (hu) |
NZ (1) | NZ532065A (hu) |
PL (1) | PL369311A1 (hu) |
SK (1) | SK2442004A3 (hu) |
TW (1) | TW200300672A (hu) |
WO (1) | WO2003049724A1 (hu) |
ZA (1) | ZA200404274B (hu) |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1530476A1 (en) * | 2002-08-14 | 2005-05-18 | Pharmacia & Upjohn Company LLC | Use of reboxetine for the treatment of hot flashes |
US20060100290A1 (en) * | 2003-07-28 | 2006-05-11 | Dunaway Leslie J | Treatment of allergic rhinitis and asthma |
EP1660064A2 (en) * | 2003-08-27 | 2006-05-31 | Eli Lilly And Company | Treatment of learning disabilities and motor skills disorder with norepinephrine reuptake inhibitors |
CN1889940A (zh) * | 2003-12-12 | 2007-01-03 | 伊莱利利公司 | 热潮红、冲动控制障碍和全身性医学病症引起的人格变化的治疗 |
BRPI0510453A (pt) * | 2004-04-30 | 2007-10-30 | Warner Lambert Co | composto substituìdos com morfolina para o tratamento de distúrbios do sistema nervoso central |
US7439399B2 (en) * | 2004-06-28 | 2008-10-21 | Teva Pharmaceutical Fine Chemicals | Processes for the preparation of atomoxetine hydrochloride |
US8580776B2 (en) * | 2007-07-10 | 2013-11-12 | The Board Of Trustees Of The University Of Illinois | Compositions and methods for treating neurodegenerating diseases |
US20100069389A1 (en) * | 2008-09-06 | 2010-03-18 | Bionevia Pharmaceuticals, Inc. | Novel forms of reboxetine |
US20100317730A1 (en) * | 2009-06-12 | 2010-12-16 | Shaya Elias K | Treatment for menopausal and perimenopausal vasomotor symptons |
TW201107485A (en) * | 2009-07-31 | 2011-03-01 | Univ Nat Taiwan | Treating negative symptoms of schizophrenia associated with defective neuregulin 1 (NRG1) |
WO2013051266A1 (ja) * | 2011-10-03 | 2013-04-11 | 独立行政法人国立長寿医療研究センター | タウ凝集阻害剤 |
EP2919788A4 (en) | 2012-11-14 | 2016-05-25 | Univ Johns Hopkins | METHODS AND COMPOSITIONS FOR THE TREATMENT OF SCHIZOPHRENIA |
US9907799B2 (en) | 2013-04-02 | 2018-03-06 | The Doshisha | Tau aggregation inhibitor |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4314081A (en) * | 1974-01-10 | 1982-02-02 | Eli Lilly And Company | Arloxyphenylpropylamines |
US5281624A (en) * | 1991-09-27 | 1994-01-25 | Eli Lilly And Company | N-alkyl-3-phenyl-3-(2-substituted phenoxy) propylamines and pharmaceutical use thereof |
US5658590A (en) * | 1995-01-11 | 1997-08-19 | Eli Lilly And Company | Treatment of attention-deficit/hyperactivity disorder |
PT1632234E (pt) * | 1999-07-01 | 2007-07-09 | Pharmacia & Upjohn Co Llc | (s,s)-reboxetina para o tratamento da síndrome de fadiga crónica |
GEP20043160B (en) * | 1999-10-13 | 2004-01-26 | Pfizer Products Inc Us | Biaryl Ether Derivatives, Pharmaceutical Compositions Containing Them and Their Use as Monoamine Reuptake Inhibitors |
AU2002243451A1 (en) * | 2001-01-02 | 2002-07-16 | Sention, Inc. | Use of catecholamine reuptake inhibitors to enhance memory |
AU2002232470B2 (en) * | 2001-01-02 | 2005-11-03 | Pharmacia & Upjohn Company Llc | New drug combinations of norepinehrine reuptake inhibitors and neuroleptic agents |
-
2002
- 2002-11-27 NZ NZ532065A patent/NZ532065A/en unknown
- 2002-11-27 MX MXPA04005716A patent/MXPA04005716A/es not_active Application Discontinuation
- 2002-11-27 CN CNA028247264A patent/CN1713900A/zh active Pending
- 2002-11-27 SK SK244-2004A patent/SK2442004A3/sk not_active Application Discontinuation
- 2002-11-27 ES ES02789574T patent/ES2295435T3/es not_active Expired - Lifetime
- 2002-11-27 DE DE60223718T patent/DE60223718T2/de not_active Expired - Fee Related
- 2002-11-27 EP EP02789574A patent/EP1458368B1/en not_active Expired - Lifetime
- 2002-11-27 CZ CZ2004709A patent/CZ2004709A3/cs unknown
- 2002-11-27 KR KR10-2004-7009039A patent/KR20040066895A/ko not_active Application Discontinuation
- 2002-11-27 PL PL02369311A patent/PL369311A1/xx unknown
- 2002-11-27 EA EA200400793A patent/EA200400793A1/ru unknown
- 2002-11-27 JP JP2003550773A patent/JP2005517647A/ja active Pending
- 2002-11-27 IL IL16198902A patent/IL161989A0/xx unknown
- 2002-11-27 US US10/496,765 patent/US20050009925A1/en not_active Abandoned
- 2002-11-27 WO PCT/US2002/036132 patent/WO2003049724A1/en active IP Right Grant
- 2002-11-27 BR BR0213581-7A patent/BR0213581A/pt not_active IP Right Cessation
- 2002-11-27 CA CA002467802A patent/CA2467802A1/en not_active Abandoned
- 2002-11-27 HU HU0402619A patent/HUP0402619A3/hu unknown
- 2002-11-27 AU AU2002352625A patent/AU2002352625A1/en not_active Abandoned
- 2002-12-05 TW TW091135296A patent/TW200300672A/zh unknown
- 2002-12-05 MY MYPI20024591A patent/MY136367A/en unknown
-
2004
- 2004-05-31 ZA ZA200404274A patent/ZA200404274B/en unknown
- 2004-06-09 HR HR20040528A patent/HRPK20040528B3/xx not_active IP Right Cessation
- 2004-06-09 EC EC2004005145A patent/ECSP045145A/es unknown
- 2004-06-09 CO CO04054292A patent/CO5590907A2/es not_active Application Discontinuation
- 2004-07-09 NO NO20042904A patent/NO20042904L/no not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
CZ2004709A3 (cs) | 2004-10-13 |
PL369311A1 (en) | 2005-04-18 |
DE60223718T2 (de) | 2008-10-30 |
CN1713900A (zh) | 2005-12-28 |
EP1458368A1 (en) | 2004-09-22 |
HRPK20040528B3 (en) | 2006-03-31 |
MXPA04005716A (es) | 2004-12-06 |
DE60223718D1 (de) | 2008-01-03 |
ECSP045145A (es) | 2004-07-23 |
WO2003049724A1 (en) | 2003-06-19 |
NZ532065A (en) | 2007-03-30 |
SK2442004A3 (en) | 2004-12-01 |
ES2295435T3 (es) | 2008-04-16 |
US20050009925A1 (en) | 2005-01-13 |
JP2005517647A (ja) | 2005-06-16 |
HRP20040528A2 (en) | 2004-10-31 |
KR20040066895A (ko) | 2004-07-27 |
CO5590907A2 (es) | 2005-12-30 |
IL161989A0 (en) | 2005-11-20 |
AU2002352625A1 (en) | 2003-06-23 |
EP1458368B1 (en) | 2007-11-21 |
EA200400793A1 (ru) | 2004-10-28 |
ZA200404274B (en) | 2005-09-13 |
HUP0402619A3 (en) | 2008-04-28 |
TW200300672A (en) | 2003-06-16 |
NO20042904L (no) | 2004-09-07 |
MY136367A (en) | 2008-09-30 |
CA2467802A1 (en) | 2003-06-19 |
BR0213581A (pt) | 2004-08-24 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FD9A | Lapse of provisional protection due to non-payment of fees |