HUP0302436A2 - Antidepresszáns gyógyszerek által kiváltott szexuális rendellenességek kezelése apomorfinnal - Google Patents
Antidepresszáns gyógyszerek által kiváltott szexuális rendellenességek kezelése apomorfinnalInfo
- Publication number
- HUP0302436A2 HUP0302436A2 HU0302436A HUP0302436A HUP0302436A2 HU P0302436 A2 HUP0302436 A2 HU P0302436A2 HU 0302436 A HU0302436 A HU 0302436A HU P0302436 A HUP0302436 A HU P0302436A HU P0302436 A2 HUP0302436 A2 HU P0302436A2
- Authority
- HU
- Hungary
- Prior art keywords
- apomorphine
- treatment
- sexual dysfunction
- induced sexual
- patient
- Prior art date
Links
- 239000000935 antidepressant agent Substances 0.000 title abstract 3
- VMWNQDUVQKEIOC-CYBMUJFWSA-N apomorphine Chemical compound C([C@H]1N(C)CC2)C3=CC=C(O)C(O)=C3C3=C1C2=CC=C3 VMWNQDUVQKEIOC-CYBMUJFWSA-N 0.000 title abstract 2
- 229960004046 apomorphine Drugs 0.000 title abstract 2
- 201000001880 Sexual dysfunction Diseases 0.000 title 1
- 231100000872 sexual dysfunction Toxicity 0.000 title 1
- 229940005513 antidepressants Drugs 0.000 abstract 2
- 229940123685 Monoamine oxidase inhibitor Drugs 0.000 abstract 1
- 229940123445 Tricyclic antidepressant Drugs 0.000 abstract 1
- 230000001430 anti-depressive effect Effects 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 239000002899 monoamine oxidase inhibitor Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 229940124834 selective serotonin reuptake inhibitor Drugs 0.000 abstract 1
- 239000012896 selective serotonin reuptake inhibitor Substances 0.000 abstract 1
- 208000012201 sexual and gender identity disease Diseases 0.000 abstract 1
- 208000015891 sexual disease Diseases 0.000 abstract 1
- 239000003029 tricyclic antidepressant agent Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/473—Quinolines; Isoquinolines ortho- or peri-condensed with carbocyclic ring systems, e.g. acridines, phenanthridines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/138—Aryloxyalkylamines, e.g. propranolol, tamoxifen, phenoxybenzamine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/4525—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with oxygen as a ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4738—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
- A61K31/4745—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenantrolines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/485—Morphinan derivatives, e.g. morphine, codeine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
Landscapes
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Neurosurgery (AREA)
- Emergency Medicine (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Pain & Pain Management (AREA)
- Psychiatry (AREA)
- Gynecology & Obstetrics (AREA)
- Hospice & Palliative Care (AREA)
- Otolaryngology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
- Medicinal Preparation (AREA)
Abstract
A jelen találmány szexuális rendellenességek kezelésére szolgálóeljárásra vonatkozik az erre rászoruló betegben, aki antidepresszánsgyógyszert szed, amely eljárás magában foglalja az apomorfin vagy egygyógyszerészetileg elfogadható sója terápiásan hatékony mennyiségénekbeadását az említett betegnek. Az eljárás antidepresszánsokat, mintpl. triciklusos antidepresszánsokat, monoaminoxidáz-inhibitorokat vagyszelektív szerotoninfelvétel-inhibitorokat szedő betegek esetébenhasznosítható. Ó
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US24903100P | 2000-11-15 | 2000-11-15 | |
PCT/US2001/043933 WO2002039879A2 (en) | 2000-11-15 | 2001-11-14 | Treatment of anti-depression drug-induced sexual dysfunction with apomorphine |
Publications (2)
Publication Number | Publication Date |
---|---|
HUP0302436A2 true HUP0302436A2 (hu) | 2003-11-28 |
HUP0302436A3 HUP0302436A3 (en) | 2004-10-28 |
Family
ID=22941748
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HU0302436A HUP0302436A3 (en) | 2000-11-15 | 2001-11-14 | Treatment of anti-depression drug-induced sexual dysfunction with apomorphine |
Country Status (18)
Country | Link |
---|---|
US (1) | US6528521B2 (hu) |
EP (1) | EP1341536A4 (hu) |
JP (1) | JP2004513899A (hu) |
KR (1) | KR20030077538A (hu) |
CN (1) | CN1486183A (hu) |
AU (1) | AU2002235129A1 (hu) |
BG (1) | BG107874A (hu) |
BR (1) | BR0111982A (hu) |
CA (1) | CA2429047A1 (hu) |
CZ (1) | CZ20031540A3 (hu) |
HU (1) | HUP0302436A3 (hu) |
IL (1) | IL155667A0 (hu) |
MX (1) | MXPA03004288A (hu) |
NO (1) | NO20032189L (hu) |
PL (1) | PL361875A1 (hu) |
SK (1) | SK7422003A3 (hu) |
WO (1) | WO2002039879A2 (hu) |
ZA (1) | ZA200303471B (hu) |
Families Citing this family (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6787532B2 (en) * | 2000-08-05 | 2004-09-07 | Smithkline Beecham Corporation | Formulation containing anti-inflammatory androstane derivatives |
CA2522231A1 (en) * | 2003-04-14 | 2004-10-21 | Vectura Ltd | Pharmaceutical compositions comprising apomorphine for pulmonary inhalation |
US20040204439A1 (en) * | 2003-04-14 | 2004-10-14 | Staniforth John Nicholas | Composition, device, and method for treating sexual dysfunction via inhalation |
WO2005023767A2 (en) | 2003-09-10 | 2005-03-17 | Brentwood Equities Ltd. | Diastereomers of 4-aryloxy-3-hydroxypiperidines |
GB0425758D0 (en) | 2004-11-23 | 2004-12-22 | Vectura Ltd | Preparation of pharmaceutical compositions |
GB0721394D0 (en) * | 2007-10-31 | 2007-12-12 | Vectura Group Plc | Compositions for trating parkinson's disease |
WO2012083269A1 (en) | 2010-12-16 | 2012-06-21 | Cynapsus Therapeutics, Inc. | Sublingual films |
WO2014105655A1 (en) | 2012-12-24 | 2014-07-03 | Neurogastrx, Inc. | Methods for treating gi tract disorders |
CA3019769C (en) * | 2015-04-21 | 2021-10-12 | Sunovion Pharmaceuticals Inc. | Methods of treating parkinson's disease by administration of apomorphine to an oral mucosa |
WO2017168174A1 (en) | 2016-04-02 | 2017-10-05 | N4 Pharma Uk Limited | New pharmaceutical forms of sildenafil |
US11382867B2 (en) | 2018-01-18 | 2022-07-12 | Leukos Biotech, S. L. | Apomorphine-palmitic acid cocrystal solid particle crystalline form |
US11717495B2 (en) * | 2020-03-16 | 2023-08-08 | Vella Bioscience, Inc. | Use of cannabinoids in treating anti-depressant-induced female sexual dysfunction |
US10836757B1 (en) | 2020-04-02 | 2020-11-17 | Neurogastrx, Inc. | Polymorphic forms of metopimazine |
CN115671106B (zh) * | 2021-07-21 | 2024-03-19 | 广州新济药业科技有限公司 | 吗啡的应用 |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4521421A (en) * | 1983-09-26 | 1985-06-04 | Eli Lilly And Company | Treatment of sexual dysfunction |
ES2239369T3 (es) | 1993-03-26 | 2005-09-16 | Franciscus Wilhelmus Henricus Maria Merkus | Composiciones farmaceuticas para administracion intranasal de dihidroergotamina. |
PT758895E (pt) | 1994-04-22 | 2000-05-31 | Univ Kingston | Formas de dosagem sublingual contendo apomorfina para uso no tratamento da disfuncao erectil |
US5562917A (en) | 1994-12-23 | 1996-10-08 | Pentech Pharmaceuticals, Inc. | Transdermal administration of apomorphine |
US5888534A (en) * | 1995-06-13 | 1999-03-30 | Pentech Pharmaceuticals, Inc. | Controlled release of drugs delivered by sublingual or buccal administration |
DK0914097T3 (da) | 1996-03-12 | 2002-04-29 | Alza Corp | Sammensætning og doseringsform omfattende opioid antagonist |
US5897864A (en) | 1996-05-23 | 1999-04-27 | Cohen; Alan J. | Method for treating sexual dysfunction disorders with compositions containing ginkgo biloba |
AU731349B2 (en) * | 1996-12-02 | 2001-03-29 | Merck Sharp & Dohme Limited | Use of NK-1 receptor antagonists for treating sexual dysfunctions |
US5945117A (en) | 1998-01-30 | 1999-08-31 | Pentech Pharmaceuticals, Inc. | Treatment of female sexual dysfunction |
US6399826B1 (en) * | 1999-08-11 | 2002-06-04 | Sepracor Inc. | Salts of sibutramine metabolites, methods of making sibutramine metabolites and intermediates useful in the same, and methods of treating pain |
-
2001
- 2001-11-14 IL IL15566701A patent/IL155667A0/xx unknown
- 2001-11-14 SK SK742-2003A patent/SK7422003A3/sk not_active Application Discontinuation
- 2001-11-14 AU AU2002235129A patent/AU2002235129A1/en not_active Abandoned
- 2001-11-14 CN CNA018220282A patent/CN1486183A/zh active Pending
- 2001-11-14 MX MXPA03004288A patent/MXPA03004288A/es unknown
- 2001-11-14 EP EP01985480A patent/EP1341536A4/en not_active Withdrawn
- 2001-11-14 JP JP2002542257A patent/JP2004513899A/ja active Pending
- 2001-11-14 WO PCT/US2001/043933 patent/WO2002039879A2/en not_active Application Discontinuation
- 2001-11-14 BR BR0111982-6A patent/BR0111982A/pt not_active IP Right Cessation
- 2001-11-14 CA CA002429047A patent/CA2429047A1/en not_active Abandoned
- 2001-11-14 HU HU0302436A patent/HUP0302436A3/hu unknown
- 2001-11-14 KR KR10-2003-7006518A patent/KR20030077538A/ko not_active Application Discontinuation
- 2001-11-14 US US09/993,782 patent/US6528521B2/en not_active Expired - Fee Related
- 2001-11-14 PL PL01361875A patent/PL361875A1/xx not_active Application Discontinuation
- 2001-11-14 CZ CZ20031540A patent/CZ20031540A3/cs unknown
-
2003
- 2003-05-06 ZA ZA200303471A patent/ZA200303471B/en unknown
- 2003-05-14 NO NO20032189A patent/NO20032189L/no unknown
- 2003-06-04 BG BG107874A patent/BG107874A/bg unknown
Also Published As
Publication number | Publication date |
---|---|
CZ20031540A3 (cs) | 2004-05-12 |
BG107874A (bg) | 2004-01-30 |
US20020115683A1 (en) | 2002-08-22 |
MXPA03004288A (es) | 2004-09-10 |
IL155667A0 (en) | 2003-11-23 |
EP1341536A2 (en) | 2003-09-10 |
KR20030077538A (ko) | 2003-10-01 |
US6528521B2 (en) | 2003-03-04 |
BR0111982A (pt) | 2003-10-28 |
JP2004513899A (ja) | 2004-05-13 |
EP1341536A4 (en) | 2007-08-01 |
CN1486183A (zh) | 2004-03-31 |
ZA200303471B (en) | 2004-08-06 |
SK7422003A3 (en) | 2004-01-08 |
PL361875A1 (en) | 2004-10-04 |
WO2002039879A2 (en) | 2002-05-23 |
NO20032189D0 (no) | 2003-05-14 |
AU2002235129A1 (en) | 2002-05-27 |
NO20032189L (no) | 2003-07-08 |
WO2002039879A3 (en) | 2002-07-25 |
HUP0302436A3 (en) | 2004-10-28 |
CA2429047A1 (en) | 2002-05-23 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FD9A | Lapse of provisional protection due to non-payment of fees |