DE60222420T2 - Verfahren zur hydrolyse von milcheiweissen - Google Patents
Verfahren zur hydrolyse von milcheiweissen Download PDFInfo
- Publication number
- DE60222420T2 DE60222420T2 DE60222420T DE60222420T DE60222420T2 DE 60222420 T2 DE60222420 T2 DE 60222420T2 DE 60222420 T DE60222420 T DE 60222420T DE 60222420 T DE60222420 T DE 60222420T DE 60222420 T2 DE60222420 T2 DE 60222420T2
- Authority
- DE
- Germany
- Prior art keywords
- protein
- casein
- hydrolyzed
- composition
- whey
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
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Classifications
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23J—PROTEIN COMPOSITIONS FOR FOODSTUFFS; WORKING-UP PROTEINS FOR FOODSTUFFS; PHOSPHATIDE COMPOSITIONS FOR FOODSTUFFS
- A23J3/00—Working-up of proteins for foodstuffs
- A23J3/30—Working-up of proteins for foodstuffs by hydrolysis
- A23J3/32—Working-up of proteins for foodstuffs by hydrolysis using chemical agents
- A23J3/34—Working-up of proteins for foodstuffs by hydrolysis using chemical agents using enzymes
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23J—PROTEIN COMPOSITIONS FOR FOODSTUFFS; WORKING-UP PROTEINS FOR FOODSTUFFS; PHOSPHATIDE COMPOSITIONS FOR FOODSTUFFS
- A23J3/00—Working-up of proteins for foodstuffs
- A23J3/30—Working-up of proteins for foodstuffs by hydrolysis
- A23J3/32—Working-up of proteins for foodstuffs by hydrolysis using chemical agents
- A23J3/34—Working-up of proteins for foodstuffs by hydrolysis using chemical agents using enzymes
- A23J3/341—Working-up of proteins for foodstuffs by hydrolysis using chemical agents using enzymes of animal proteins
- A23J3/343—Working-up of proteins for foodstuffs by hydrolysis using chemical agents using enzymes of animal proteins of dairy proteins
- A23J3/344—Working-up of proteins for foodstuffs by hydrolysis using chemical agents using enzymes of animal proteins of dairy proteins of casein
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
- A23L2/00—Non-alcoholic beverages; Dry compositions or concentrates therefor; Preparation or treatment thereof
- A23L2/52—Adding ingredients
- A23L2/66—Proteins
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/17—Amino acids, peptides or proteins
- A23L33/18—Peptides; Protein hydrolysates
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/17—Amino acids, peptides or proteins
- A23L33/19—Dairy proteins
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- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Nutrition Science (AREA)
- Engineering & Computer Science (AREA)
- Food Science & Technology (AREA)
- Polymers & Plastics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Mycology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Zoology (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Dairy Products (AREA)
- Fodder In General (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP01202749 | 2001-07-18 | ||
| EP01202749 | 2001-07-18 | ||
| PCT/EP2002/008072 WO2003007730A1 (en) | 2001-07-18 | 2002-07-18 | Process for the hydrolysis of milk proteins |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE60222420D1 DE60222420D1 (de) | 2007-10-25 |
| DE60222420T2 true DE60222420T2 (de) | 2008-06-12 |
Family
ID=8180654
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE60222420T Expired - Lifetime DE60222420T2 (de) | 2001-07-18 | 2002-07-18 | Verfahren zur hydrolyse von milcheiweissen |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US7648721B2 (https=) |
| EP (1) | EP1406509B1 (https=) |
| JP (1) | JP2004521653A (https=) |
| KR (1) | KR20040026683A (https=) |
| CN (1) | CN1231137C (https=) |
| AT (1) | ATE372689T1 (https=) |
| AU (1) | AU2002325890B2 (https=) |
| BR (1) | BR0210680A (https=) |
| CA (1) | CA2452765C (https=) |
| DE (1) | DE60222420T2 (https=) |
| ES (1) | ES2291493T3 (https=) |
| MX (1) | MXPA04000480A (https=) |
| NZ (1) | NZ530165A (https=) |
| RU (1) | RU2292155C2 (https=) |
| WO (1) | WO2003007730A1 (https=) |
| ZA (1) | ZA200400287B (https=) |
Families Citing this family (45)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1231137C (zh) | 2001-07-18 | 2005-12-14 | Dsmip资产有限公司 | 乳类蛋白质水解的方法 |
| DE10331202A1 (de) | 2003-07-10 | 2005-03-31 | S.K. Enterprise Gmbh | Verwendung von Molkenpermeat zur Behandlung des Metabolischen Syndroms |
| DK1663298T3 (da) * | 2003-09-23 | 2019-10-14 | Dsm Ip Assets Bv | Anvendelse af prolinspecifikke endoproteaser til hydrolyse af peptider og proteiner |
| ATE551048T1 (de) * | 2004-06-28 | 2012-04-15 | Dsm Ip Assets Bv | Proteinhydrolysate enthaltende kosmetische zusammensetzungen |
| CA2569926A1 (en) * | 2004-07-12 | 2006-01-19 | Dsm Ip Assets B.V. | Blood pressure lowering protein hydrolysates |
| NL1026931C2 (nl) * | 2004-08-31 | 2006-03-01 | Friesland Brands Bv | ACE-remmende wei-hydrolysaten. |
| JP4723638B2 (ja) * | 2005-04-26 | 2011-07-13 | マッセイ ユニバーシティー | 脂質封入 |
| CN101193562B (zh) * | 2005-06-10 | 2012-10-10 | 卡尔皮斯株式会社 | 饮料用组合物的防异臭方法 |
| ES2463724T3 (es) * | 2005-10-11 | 2014-05-29 | Probiotical S.P.A. | Procedimiento de preparación de cultivos bacterianos probióticos analérgicos y uso relacionado |
| AU2007211641B2 (en) * | 2006-02-02 | 2012-09-06 | Dsm Ip Assets B.V. | Food product comprising a proline specific protease |
| EP2003989A1 (en) | 2006-03-31 | 2008-12-24 | DSMIP Assets B.V. | Process for the hydrolysis of milk proteins |
| EP1867237A1 (en) * | 2006-06-15 | 2007-12-19 | Nestec S.A. | Hypoallergenic Egg |
| DE102006036285A1 (de) * | 2006-08-03 | 2008-02-07 | "S.U.K." Beteiligungs Gmbh | Fraktionen aus Molkepermeat und deren Verwendung zur Prävention und Therapie des Typ-2 Diabetes und des Metabolischen Syndroms |
| RU2341109C1 (ru) * | 2007-08-28 | 2008-12-20 | Государственное образовательное учреждение высшего профессионального образования Кемеровский технологический институт пищевой промышленности | Способ получения пищевого продукта для больных фенилкетонурией |
| CN101925674A (zh) * | 2007-11-23 | 2010-12-22 | 帝斯曼知识产权资产管理有限公司 | 改进的生物活性肽生产 |
| ATE539150T1 (de) | 2008-06-03 | 2012-01-15 | Novozymes As | Verfahren zur herstellung eines caseinhydrolysats |
| US8498729B2 (en) | 2008-08-29 | 2013-07-30 | Smp Logic Systems Llc | Manufacturing execution system for use in manufacturing baby formula |
| JP5657200B2 (ja) * | 2008-09-05 | 2015-01-21 | サントリー食品インターナショナル株式会社 | 乳清タンパク質の含有量が低減された乳組成物及び乳入り飲料 |
| EP2165713B1 (en) * | 2008-09-19 | 2012-11-14 | Nestec S.A. | Whey and thymus function |
| CA2740911C (en) * | 2008-10-17 | 2014-07-29 | Nestec S.A. | Whey protein compositions, methods and uses |
| JP5329280B2 (ja) * | 2009-03-31 | 2013-10-30 | テルモ株式会社 | 酸性タイプ液状経腸栄養剤 |
| JP5892948B2 (ja) | 2010-01-29 | 2016-03-23 | アボット・ラボラトリーズＡｂｂｏｔｔ Ｌａｂｏｒａｔｏｒｉｅｓ | カルシウムｈｍｂを含む栄養エマルジョン |
| BR112012018174A2 (pt) | 2010-01-29 | 2019-08-27 | Abbott Lab | líquidos nutricionais embalados assepticamente compreendendo hmb. |
| US9693577B2 (en) | 2010-01-29 | 2017-07-04 | Abbott Laboratories | Method of preparing a nutritional powder comprising spray dried HMB |
| TWI526161B (zh) * | 2010-06-10 | 2016-03-21 | 亞培公司 | 包含鈣ｈｍｂ及可溶性蛋白質之實質上透明營養液 |
| FI124323B (fi) * | 2011-02-18 | 2014-06-30 | Valio Oy | Maitopohjainen tuote ja menetelmä sen valmistamiseksi |
| WO2014060495A1 (en) * | 2012-10-19 | 2014-04-24 | Dsm Ip Assets B.V. | Process for the production of an infant formula |
| CN104046673B (zh) * | 2013-03-14 | 2020-07-21 | 中国食品发酵工业研究院 | 一种含CPPs的低致敏性酪蛋白肽全粉工业化制造方法及其应用 |
| US9138455B2 (en) | 2013-03-15 | 2015-09-22 | Mead Johnson Nutrition Company | Activating adiponectin by casein hydrolysate |
| US9289461B2 (en) | 2013-03-15 | 2016-03-22 | Mead Johnson Nutrition Company | Reducing the risk of autoimmune disease |
| US9352020B2 (en) | 2013-03-15 | 2016-05-31 | Mead Johnson Nutrition Company | Reducing proinflammatory response |
| US9345741B2 (en) | 2013-03-15 | 2016-05-24 | Mead Johnson Nutrition Company | Nutritional composition containing a peptide component with adiponectin simulating properties and uses thereof |
| US9345727B2 (en) | 2013-03-15 | 2016-05-24 | Mead Johnson Nutrition Company | Nutritional compositions containing a peptide component and uses thereof |
| US8889633B2 (en) | 2013-03-15 | 2014-11-18 | Mead Johnson Nutrition Company | Nutritional compositions containing a peptide component with anti-inflammatory properties and uses thereof |
| US20140328970A1 (en) * | 2013-05-03 | 2014-11-06 | Mead Johnson Nutrition Company | Nutritional Composition Comprising Whey and Hydrolyzed Casein and Uses Thereof |
| AU2014318367A1 (en) * | 2013-09-16 | 2016-05-12 | Glanbia Nutritionals (Ireland) PLC | Method for inhibiting aggregate formation during protein hydrolysis |
| KR101559448B1 (ko) | 2013-09-17 | 2015-10-13 | 동서식품 주식회사 | 커피 크리머용 우유 단백질의 제조방법 및 이를 이용한 커피 크리머 제조방법 |
| RU2692549C2 (ru) * | 2014-06-25 | 2019-06-25 | Нестек С.А. | Жидкая молочная смесь для кулинарных пищевых продуктов |
| US20170156369A1 (en) * | 2014-07-14 | 2017-06-08 | Rebecca Lynn Scotland | Isolation of Plant Oligopeptides and Uses Thereof |
| US10820618B2 (en) * | 2015-12-18 | 2020-11-03 | Societe Des Produits Nestle S.A. | Heat sterilized high protein compositions with hydrolyzed protein from a continuous process with at least one endopeptidase |
| CN106857819A (zh) * | 2016-10-21 | 2017-06-20 | 帝斯曼知识产权资产管理有限公司 | 易消化牛奶及其制备方法 |
| CN108588156A (zh) * | 2018-04-24 | 2018-09-28 | 浙江大学 | 一种水牛乳酪蛋白抗氧化活性肽的制备方法 |
| WO2020130803A1 (en) * | 2018-12-21 | 2020-06-25 | N.V. Nutricia | Protein compositions with high isoelectric proteins |
| CN114540449B (zh) * | 2022-03-02 | 2024-04-02 | 江南大学 | 消化率提升的高谷氨酰胺含量的水解乳清蛋白粉及其制备 |
| CN115404258A (zh) * | 2022-08-26 | 2022-11-29 | 华南理工大学 | 一种改性玉米蛋白及其制备方法与应用 |
Family Cites Families (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SU738583A1 (ru) * | 1977-12-05 | 1980-06-05 | Московский технологический институт мясной и молочной промышленности | Способ получени гидролизата казеина |
| US4600588A (en) | 1980-08-20 | 1986-07-15 | Ernster John H | Milk protein hydrolysate and process of preparation |
| US5405756A (en) | 1982-03-30 | 1995-04-11 | Meiji Seika Kaisha, Ltd. | Transparent acid drink containing acid-soluble casein phosphopeptide |
| GB8528100D0 (en) | 1985-11-14 | 1985-12-18 | Imp Biotechnology | Zenymatic hydrolysis of proteins |
| DE3905194A1 (de) | 1989-02-21 | 1990-08-23 | Roehm Gmbh | Verfahren zur herstellung von protein-hydrolysaten mit niedrigem gehalt an bitterstoffen |
| JPH0517368A (ja) * | 1991-07-05 | 1993-01-26 | Morinaga Milk Ind Co Ltd | 抗アレルギー性母乳強化組成物 |
| US5486461A (en) * | 1991-11-08 | 1996-01-23 | Novo Nordisk A/S | Casein hydrolyzate and method for production of such casein hydrolyzate |
| FI94089C (fi) | 1992-12-10 | 1995-07-25 | Valio Oy | Menetelmä allergiaa aiheuttavien yhdisteiden poistamiseksi proteiinipitoisista koostumuksista |
| US5405637A (en) * | 1993-06-30 | 1995-04-11 | Bristol-Myers Squibb Company | Milk protein partial hydrolysate and infant formula containing same |
| EP0785726B1 (en) | 1994-10-26 | 2004-01-07 | Novozymes A/S | Method for production of a milk protein hydrolyzate |
| US5844086A (en) * | 1996-01-31 | 1998-12-01 | Stilts Corporation | Oil seed protein extraction |
| ATE218036T1 (de) | 1996-12-23 | 2002-06-15 | Dsm Nv | Verfahren zur herstellung eines proteinhydrolysates |
| JPH11243866A (ja) | 1998-03-05 | 1999-09-14 | Morinaga Milk Ind Co Ltd | カゼイン加水分解物及びその製造法 |
| EP1062873A1 (en) * | 1999-12-13 | 2000-12-27 | N.V. Nutricia | Improved infant formula, protein hydrolysate for use in such an infant formula, and method for producing such a hydrolysate |
| WO2002032231A1 (en) | 2000-10-19 | 2002-04-25 | Edens, Luppo | Protein hydrolysates |
| CA2706364A1 (en) | 2000-12-07 | 2002-06-13 | Dsm Ip Assets B.V. | Method for the prevention or reduction of haze in beverages |
| ATE475324T1 (de) | 2000-12-07 | 2010-08-15 | Dsm Ip Assets Bv | Mit carboxy-terminal prolin peptide angereicherte proteinhydrolysate |
| WO2002068623A2 (en) | 2001-02-23 | 2002-09-06 | Dsm Ip Assets B.V. | Genes encoding proteolytic enzymes from aspargilli |
| CN1231137C (zh) | 2001-07-18 | 2005-12-14 | Dsmip资产有限公司 | 乳类蛋白质水解的方法 |
| ES2540926T3 (es) | 2002-06-04 | 2015-07-14 | Dsm Ip Assets B.V. | Hidrolizado de proteínas rico en tripéptidos |
| AU2003228145B2 (en) | 2002-06-07 | 2009-10-08 | Dsm Ip Assets B.V. | Improved method for the prevention or reduction of haze in beverages |
| AU2003264256A1 (en) | 2002-09-04 | 2004-03-29 | Dsm Ip Assets B.V. | A nutritional and therapeutic composition of an insulin sensitizer and a peptide fraction |
| DK1663298T3 (da) | 2003-09-23 | 2019-10-14 | Dsm Ip Assets Bv | Anvendelse af prolinspecifikke endoproteaser til hydrolyse af peptider og proteiner |
-
2002
- 2002-07-18 CN CNB028141520A patent/CN1231137C/zh not_active Expired - Fee Related
- 2002-07-18 ES ES02760254T patent/ES2291493T3/es not_active Expired - Lifetime
- 2002-07-18 BR BR0210680-9A patent/BR0210680A/pt not_active IP Right Cessation
- 2002-07-18 EP EP02760254A patent/EP1406509B1/en not_active Expired - Lifetime
- 2002-07-18 JP JP2003513349A patent/JP2004521653A/ja active Pending
- 2002-07-18 MX MXPA04000480A patent/MXPA04000480A/es active IP Right Grant
- 2002-07-18 US US10/483,948 patent/US7648721B2/en not_active Expired - Fee Related
- 2002-07-18 WO PCT/EP2002/008072 patent/WO2003007730A1/en not_active Ceased
- 2002-07-18 KR KR10-2004-7000730A patent/KR20040026683A/ko not_active Withdrawn
- 2002-07-18 AT AT02760254T patent/ATE372689T1/de not_active IP Right Cessation
- 2002-07-18 DE DE60222420T patent/DE60222420T2/de not_active Expired - Lifetime
- 2002-07-18 RU RU2004104639/13A patent/RU2292155C2/ru not_active IP Right Cessation
- 2002-07-18 CA CA2452765A patent/CA2452765C/en not_active Expired - Fee Related
- 2002-07-18 AU AU2002325890A patent/AU2002325890B2/en not_active Ceased
- 2002-07-18 NZ NZ530165A patent/NZ530165A/en not_active IP Right Cessation
-
2004
- 2004-01-14 ZA ZA200400287A patent/ZA200400287B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| DE60222420D1 (de) | 2007-10-25 |
| JP2004521653A (ja) | 2004-07-22 |
| ES2291493T3 (es) | 2008-03-01 |
| KR20040026683A (ko) | 2004-03-31 |
| CA2452765C (en) | 2010-09-28 |
| CN1231137C (zh) | 2005-12-14 |
| NZ530165A (en) | 2004-08-27 |
| US20050175622A1 (en) | 2005-08-11 |
| RU2292155C2 (ru) | 2007-01-27 |
| WO2003007730A1 (en) | 2003-01-30 |
| ZA200400287B (en) | 2004-10-14 |
| BR0210680A (pt) | 2004-09-21 |
| EP1406509A1 (en) | 2004-04-14 |
| ATE372689T1 (de) | 2007-09-15 |
| EP1406509B1 (en) | 2007-09-12 |
| RU2004104639A (ru) | 2005-05-10 |
| MXPA04000480A (es) | 2004-07-23 |
| AU2002325890B2 (en) | 2007-10-04 |
| US7648721B2 (en) | 2010-01-19 |
| CN1527669A (zh) | 2004-09-08 |
| CA2452765A1 (en) | 2003-01-30 |
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