DE60221238D1 - Herstellungsverfahren für niedrig dosierte pharmazeutische zusammensetzung - Google Patents

Herstellungsverfahren für niedrig dosierte pharmazeutische zusammensetzung

Info

Publication number
DE60221238D1
DE60221238D1 DE60221238T DE60221238T DE60221238D1 DE 60221238 D1 DE60221238 D1 DE 60221238D1 DE 60221238 T DE60221238 T DE 60221238T DE 60221238 T DE60221238 T DE 60221238T DE 60221238 D1 DE60221238 D1 DE 60221238D1
Authority
DE
Germany
Prior art keywords
pharmaceutical composition
manufacturing low
low dosed
dosed pharmaceutical
manufacturing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE60221238T
Other languages
English (en)
Other versions
DE60221238T2 (de
Inventor
Daniel S Gierer
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Products Inc
Original Assignee
Pfizer Products Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Products Inc filed Critical Pfizer Products Inc
Application granted granted Critical
Publication of DE60221238D1 publication Critical patent/DE60221238D1/de
Publication of DE60221238T2 publication Critical patent/DE60221238T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2009—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2095—Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/30—Oestrogens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/32—Antioestrogens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Endocrinology (AREA)
  • Diabetes (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Inorganic Chemistry (AREA)
  • Reproductive Health (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DE60221238T 2001-05-01 2002-03-13 Herstellungsverfahren für niedrig dosierte pharmazeutische zusammensetzung Expired - Fee Related DE60221238T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US28784101P 2001-05-01 2001-05-01
US287841P 2001-05-01
PCT/IB2002/000766 WO2002087546A2 (en) 2001-05-01 2002-03-13 Method for manufacturing a low dose pharmaceutical composition

Publications (2)

Publication Number Publication Date
DE60221238D1 true DE60221238D1 (de) 2007-08-30
DE60221238T2 DE60221238T2 (de) 2007-10-31

Family

ID=23104578

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60221238T Expired - Fee Related DE60221238T2 (de) 2001-05-01 2002-03-13 Herstellungsverfahren für niedrig dosierte pharmazeutische zusammensetzung

Country Status (44)

Country Link
US (2) US7037530B2 (de)
EP (1) EP1383482B1 (de)
JP (1) JP2004531537A (de)
KR (1) KR100568380B1 (de)
CN (1) CN1240375C (de)
AP (1) AP2003002900A0 (de)
AR (1) AR033288A1 (de)
AT (1) ATE367152T1 (de)
AU (1) AU2002236166B2 (de)
BG (1) BG108297A (de)
BR (1) BR0209283A (de)
CA (1) CA2445519C (de)
CZ (1) CZ20032959A3 (de)
DE (1) DE60221238T2 (de)
DK (1) DK1383482T3 (de)
DO (1) DOP2002000389A (de)
EA (1) EA005949B1 (de)
EC (1) ECSP034826A (de)
EE (1) EE200300537A (de)
ES (1) ES2286226T3 (de)
GE (1) GEP20053654B (de)
GT (1) GT200200078A (de)
HK (1) HK1065705A1 (de)
HR (1) HRP20030858A2 (de)
HU (1) HUP0401391A3 (de)
IL (1) IL158390A0 (de)
IS (1) IS6985A (de)
MA (1) MA27017A1 (de)
MX (1) MXPA03009391A (de)
NO (1) NO20034709L (de)
NZ (1) NZ528886A (de)
OA (1) OA12596A (de)
PA (1) PA8544401A1 (de)
PE (1) PE20021137A1 (de)
PL (1) PL366453A1 (de)
PT (1) PT1383482E (de)
SK (1) SK286536B6 (de)
TN (1) TNSN03106A1 (de)
TW (1) TWI264311B (de)
UA (1) UA75135C2 (de)
UY (1) UY27277A1 (de)
WO (1) WO2002087546A2 (de)
YU (1) YU81503A (de)
ZA (1) ZA200307819B (de)

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MXPA04009259A (es) 2002-03-28 2005-01-25 Pfizer Prod Inc Lasofoxifeno racemico purificado y d-tartrato de lasofoxifeno purificado y un metodo para la purificacion efectiva del lasofoxifeno racemico.
PA8576201A1 (es) * 2002-07-10 2004-05-26 Pfizer Prod Inc Composicion farmaceutica que tiene una distribucion y potencia uniforme de farmaco
US7799273B2 (en) 2004-05-06 2010-09-21 Smp Logic Systems Llc Manufacturing execution system for validation, quality and risk assessment and monitoring of pharmaceutical manufacturing processes
US7444197B2 (en) 2004-05-06 2008-10-28 Smp Logic Systems Llc Methods, systems, and software program for validation and monitoring of pharmaceutical manufacturing processes
EP2023745A1 (de) * 2006-05-17 2009-02-18 WM. Wrigley Jr., Company Verfahren zur herstellung eines lebensmittelprodukts
FI20070521L (fi) 2006-11-10 2008-05-11 Atacama Labs Oy Rakeita, tabletteja ja rakeistusmenetelmä
FI20080351A0 (fi) * 2008-05-09 2008-05-09 Atacama Labs Oy Prosessi matalan lääkepitoisuuden tabletin valmistamiseksi
US8951562B2 (en) 2006-11-10 2015-02-10 Atacama Labs Oy Method and apparatus or dry granulation
US20100179110A1 (en) * 2006-12-20 2010-07-15 Mostafa Akbarieh Composition Containing a Bisphosphonic Acid in Combination with Vitamin D
US20080181972A1 (en) * 2007-01-29 2008-07-31 Valentina Amico Compositions and Methods for Maintaining, Strengthening, Improving, or Promoting Eye Health
ES2603617T3 (es) 2007-02-23 2017-02-28 Gilead Sciences, Inc. Moduladores de propiedades farmacocinéticas de la terapéutica
KR101784647B1 (ko) 2008-05-02 2017-10-11 길리애드 사이언시즈, 인코포레이티드 제약 제제의 가공성 향상을 위한 고체 담체 입자의 용도
EP2291233B1 (de) * 2008-05-09 2019-09-04 Atacama Labs Oy Verfahren für trockene granulation
US20170065529A1 (en) 2015-09-09 2017-03-09 Boehringer Ingelheim International Gmbh Pharmaceutical dosage form for immediate release of an indolinone derivative
EA029996B1 (ru) 2008-06-06 2018-06-29 Бёрингер Ингельхайм Интернациональ Гмбх Капсулярная лекарственная форма, содержащая суспензионную композицию производного индолинона
ES2520990T3 (es) * 2009-01-29 2014-11-12 Ucb Pharma, S.A. Composiciones farmacéuticas que comprenden derivados de 2-oxo-1-pirrolidina
CN104083328B (zh) * 2009-01-29 2017-04-12 Ucb生物制药私人有限公司 包含2‑氧代‑1‑吡咯烷衍生物的药物组合物
US20140350945A1 (en) * 2013-05-22 2014-11-27 Professional Compounding Centers Of America System and Method for Validation of Pharmaceutical Composition Formulations
CN103830196A (zh) * 2014-03-14 2014-06-04 王志刚 一种酒石酸拉索昔芬分散片及其制备方法
CN106176649B (zh) * 2016-08-31 2020-04-17 北京斯利安药业有限公司 叶酸vb12片及其制备方法
MX2019009777A (es) * 2017-02-17 2019-10-14 Massachusetts Inst Technology Sistemas y metodos para la fabricacion de tabletas, que incluyen tabletas farmaceuticas.
CZ309820B6 (cs) * 2021-04-23 2023-11-08 Pro.Med.Cs Praha A.S. Způsob přípravy pevné lékové formy obsahující kompozici s nízkým obsahem účinné látky

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Also Published As

Publication number Publication date
MA27017A1 (fr) 2004-12-20
ES2286226T3 (es) 2007-12-01
ZA200307819B (en) 2004-10-07
HK1065705A1 (en) 2005-03-04
ATE367152T1 (de) 2007-08-15
CA2445519C (en) 2009-01-20
EA200301040A1 (ru) 2004-04-29
MXPA03009391A (es) 2004-01-29
IS6985A (is) 2003-10-09
CN1240375C (zh) 2006-02-08
DE60221238T2 (de) 2007-10-31
HUP0401391A3 (en) 2009-06-29
BR0209283A (pt) 2004-07-13
GEP20053654B (en) 2005-11-10
CA2445519A1 (en) 2002-11-07
AR033288A1 (es) 2003-12-10
US7037530B2 (en) 2006-05-02
HRP20030858A2 (en) 2005-08-31
TNSN03106A1 (fr) 2005-12-23
US20060093667A1 (en) 2006-05-04
AP2003002900A0 (en) 2003-12-31
CN1531423A (zh) 2004-09-22
NO20034709D0 (no) 2003-10-21
OA12596A (en) 2006-06-08
PE20021137A1 (es) 2002-12-14
DOP2002000389A (es) 2002-11-30
IL158390A0 (en) 2004-05-12
WO2002087546A3 (en) 2003-02-13
BG108297A (bg) 2005-07-29
EP1383482A2 (de) 2004-01-28
NZ528886A (en) 2005-04-29
SK13552003A3 (sk) 2004-09-08
UA75135C2 (en) 2006-03-15
CZ20032959A3 (cs) 2004-01-14
GT200200078A (es) 2003-01-31
PL366453A1 (en) 2005-02-07
KR20040015226A (ko) 2004-02-18
SK286536B6 (sk) 2008-12-05
PT1383482E (pt) 2007-09-20
US7176221B2 (en) 2007-02-13
JP2004531537A (ja) 2004-10-14
AU2002236166B2 (en) 2006-12-07
US20030004182A1 (en) 2003-01-02
HUP0401391A2 (hu) 2004-12-28
EE200300537A (et) 2004-04-15
WO2002087546A2 (en) 2002-11-07
TWI264311B (en) 2006-10-21
YU81503A (sh) 2006-08-17
DK1383482T3 (da) 2007-10-29
NO20034709L (no) 2003-10-31
EP1383482B1 (de) 2007-07-18
EA005949B1 (ru) 2005-08-25
PA8544401A1 (es) 2003-07-28
ECSP034826A (es) 2004-02-26
KR100568380B1 (ko) 2006-04-05
UY27277A1 (es) 2002-11-29

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