DE602005025911D1 - Kontrastmittel für eine extrazelluläre matrix - Google Patents

Kontrastmittel für eine extrazelluläre matrix

Info

Publication number
DE602005025911D1
DE602005025911D1 DE602005025911T DE602005025911T DE602005025911D1 DE 602005025911 D1 DE602005025911 D1 DE 602005025911D1 DE 602005025911 T DE602005025911 T DE 602005025911T DE 602005025911 T DE602005025911 T DE 602005025911T DE 602005025911 D1 DE602005025911 D1 DE 602005025911D1
Authority
DE
Germany
Prior art keywords
contrastant
extra
cellular matrix
biomodifier
areas
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE602005025911T
Other languages
German (de)
English (en)
Inventor
Dagfinn Loevhaug
Morten Eriksen
Hege Fjerdingstad
Andrew Healey
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
GE Healthcare AS
Original Assignee
GE Healthcare AS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by GE Healthcare AS filed Critical GE Healthcare AS
Publication of DE602005025911D1 publication Critical patent/DE602005025911D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/001—Preparation for luminescence or biological staining
    • A61K49/0013—Luminescence
    • A61K49/0017—Fluorescence in vivo
    • A61K49/005—Fluorescence in vivo characterised by the carrier molecule carrying the fluorescent agent
    • A61K49/0056—Peptides, proteins, polyamino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/0002—General or multifunctional contrast agents, e.g. chelated agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/001—Preparation for luminescence or biological staining
    • A61K49/0013—Luminescence
    • A61K49/0017—Fluorescence in vivo
    • A61K49/0019—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules
    • A61K49/0021—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules the fluorescent group being a small organic molecule
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/001—Preparation for luminescence or biological staining
    • A61K49/0013—Luminescence
    • A61K49/0017—Fluorescence in vivo
    • A61K49/0019—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules
    • A61K49/0021—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules the fluorescent group being a small organic molecule
    • A61K49/0032—Methine dyes, e.g. cyanine dyes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A61K49/08—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
    • A61K49/085—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier conjugated systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A61K49/08—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
    • A61K49/10—Organic compounds
    • A61K49/14—Peptides, e.g. proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/0497—Organic compounds conjugates with a carrier being an organic compounds

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Radiology & Medical Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Physics & Mathematics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Optics & Photonics (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Magnetic Resonance Imaging Apparatus (AREA)
  • Steroid Compounds (AREA)
DE602005025911T 2004-11-22 2005-11-21 Kontrastmittel für eine extrazelluläre matrix Expired - Lifetime DE602005025911D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
NO20045081 2004-11-22
PCT/NO2005/000435 WO2006054904A2 (en) 2004-11-22 2005-11-21 Contrast agents to target extracellular matrix

Publications (1)

Publication Number Publication Date
DE602005025911D1 true DE602005025911D1 (de) 2011-02-24

Family

ID=36182407

Family Applications (1)

Application Number Title Priority Date Filing Date
DE602005025911T Expired - Lifetime DE602005025911D1 (de) 2004-11-22 2005-11-21 Kontrastmittel für eine extrazelluläre matrix

Country Status (17)

Country Link
US (1) US8182790B2 (https=)
EP (2) EP1814598B1 (https=)
JP (2) JP5116480B2 (https=)
KR (1) KR20070091609A (https=)
CN (1) CN101107016B (https=)
AT (1) ATE494913T1 (https=)
AU (1) AU2005307195A1 (https=)
BR (1) BRPI0518328A2 (https=)
CA (1) CA2586621A1 (https=)
DE (1) DE602005025911D1 (https=)
ES (1) ES2358745T3 (https=)
IL (1) IL182898A0 (https=)
MX (1) MX2007006050A (https=)
NO (1) NO20073039L (https=)
RU (1) RU2007118385A (https=)
WO (1) WO2006054904A2 (https=)
ZA (1) ZA200705043B (https=)

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GB0610395D0 (en) * 2006-05-25 2006-07-05 Ge Healthcare Ltd Novel imaging agents
US20100233082A1 (en) * 2006-08-28 2010-09-16 Bengt Langstrom 68GA-Labeled Peptide-Based Radiopharmaceuticals
JP2008266194A (ja) * 2007-04-19 2008-11-06 Hiroshi Tanaka 分子プローブの原料として有用な新規有機化合物
GB0722650D0 (en) * 2007-11-19 2007-12-27 Ge Healthcare Ltd Novel imaging method
WO2009074628A1 (en) * 2007-12-13 2009-06-18 INSERM (Institut National de la Santé et de la Recherche Médicale) Polypeptides, cyclic polypeptides and pharmaceutical comprising thereof for non invasive specific imaging of fibrosis
ES2658852T3 (es) 2008-01-18 2018-03-12 Visen Medical, Inc. Agentes de imaginología fluorescentes
JP5265762B2 (ja) 2008-05-13 2013-08-14 ユニバーシティ・オブ・カンザス 金属抽出ペプチド（ｍａｐ）タグおよび関連する方法
GB0814722D0 (en) * 2008-08-12 2008-09-17 Ge Healthcare Ltd Treatment monitoring
GB0910013D0 (en) * 2009-06-10 2009-07-22 Ge Healthcare Ltd PET imaging of fibogenesis
KR100991716B1 (ko) * 2009-10-22 2010-11-04 경북대학교 산학협력단 광학영상 조영제, 그 용도 및 장치
CN102504603B (zh) * 2011-10-20 2014-01-29 中国海洋大学 一种多聚物与生物染色剂的偶合物及其制备方法和用途
WO2013181461A2 (en) 2012-06-01 2013-12-05 University Of Kansas Metal abstraction peptide with superoxide dismutase activity
WO2015085005A1 (en) * 2013-12-03 2015-06-11 The General Hospital Corporation Molecular imaging probes
CN117623996B (zh) * 2022-08-10 2025-07-22 中国药科大学 一种二价keap1-nrf2抑制剂、制备方法及其医药用途

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US4687659A (en) 1984-11-13 1987-08-18 Salutar, Inc. Diamide-DTPA-paramagnetic contrast agents for MR imaging
US5268486A (en) 1986-04-18 1993-12-07 Carnegie-Mellon Unversity Method for labeling and detecting materials employing arylsulfonate cyanine dyes
US6048982A (en) 1986-04-18 2000-04-11 Carnegie Mellon University Cyanine dyes as labeling reagents for detection of biological and other materials by luminescence methods
JP3038339B2 (ja) 1988-05-02 2000-05-08 ザイナクシス・テクノロジーズ・インコーポレーテッド バイオ粒子の表面膜に対してバイオアフェクティング物質を結合する化合物
GB8903022D0 (en) * 1989-02-10 1989-03-30 Celltech Ltd Chemical compounds
JP3682974B2 (ja) 1991-11-27 2005-08-17 株式会社ファノスディベロップメント バイオ作用性物質をバイオ粒子表面膜へ結合するための化合物、組成、および方法
BR9713978A (pt) 1996-10-28 2000-05-02 Nycomed Imaging As Agente diagnóstico alvejável e/ou terapeuticamente ativo, processo para preparação e uso do mesmo, formulação combinada, e, processos para gerar imagens intensificadas de um corpo animal humano ou não-humano e para investigação in vitro de alvejamento por um agente
ES2257771T3 (es) * 1996-10-28 2006-08-01 Amersham Health As Agentes de contraste.
EP1011736A2 (en) * 1997-01-29 2000-06-28 Nycomed Imaging As Polymers
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CA2328414C (en) * 1998-05-08 2014-04-15 The Regents Of The University Of California Methods for detecting and inhibiting angiogenesis
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Also Published As

Publication number Publication date
ES2358745T3 (es) 2011-05-13
ATE494913T1 (de) 2011-01-15
KR20070091609A (ko) 2007-09-11
MX2007006050A (es) 2007-11-14
JP2008520658A (ja) 2008-06-19
US20090208412A1 (en) 2009-08-20
RU2007118385A (ru) 2008-12-27
EP2243496A3 (en) 2012-12-26
WO2006054904A2 (en) 2006-05-26
NO20073039L (no) 2007-08-16
CN101107016B (zh) 2011-11-16
ZA200705043B (en) 2008-09-25
EP1814598B1 (en) 2011-01-12
BRPI0518328A2 (pt) 2008-11-11
CN101107016A (zh) 2008-01-16
WO2006054904A3 (en) 2007-04-05
AU2005307195A1 (en) 2006-05-26
JP2012207027A (ja) 2012-10-25
CA2586621A1 (en) 2006-05-26
EP1814598A2 (en) 2007-08-08
JP5116480B2 (ja) 2013-01-09
US8182790B2 (en) 2012-05-22
IL182898A0 (en) 2007-08-19
EP2243496A2 (en) 2010-10-27

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