JP2008509921A5 - - Google Patents
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- Publication number
- JP2008509921A5 JP2008509921A5 JP2007525779A JP2007525779A JP2008509921A5 JP 2008509921 A5 JP2008509921 A5 JP 2008509921A5 JP 2007525779 A JP2007525779 A JP 2007525779A JP 2007525779 A JP2007525779 A JP 2007525779A JP 2008509921 A5 JP2008509921 A5 JP 2008509921A5
- Authority
- JP
- Japan
- Prior art keywords
- compound
- fragment
- lox
- pharmaceutical composition
- heat shock
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 150000001875 compounds Chemical class 0.000 claims 5
- 102100025386 Oxidized low-density lipoprotein receptor 1 Human genes 0.000 claims 4
- 101710199789 Oxidized low-density lipoprotein receptor 1 Proteins 0.000 claims 4
- 239000012634 fragment Substances 0.000 claims 4
- 241000124008 Mammalia Species 0.000 claims 3
- 239000008194 pharmaceutical composition Substances 0.000 claims 3
- 102000018932 HSP70 Heat-Shock Proteins Human genes 0.000 claims 2
- 108010027992 HSP70 Heat-Shock Proteins Proteins 0.000 claims 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 2
- 102000002812 Heat-Shock Proteins Human genes 0.000 claims 1
- 108010004889 Heat-Shock Proteins Proteins 0.000 claims 1
- 150000001413 amino acids Chemical class 0.000 claims 1
- 238000003745 diagnosis Methods 0.000 claims 1
- 201000010099 disease Diseases 0.000 claims 1
- 208000035475 disorder Diseases 0.000 claims 1
- 238000003384 imaging method Methods 0.000 claims 1
- 238000000338 in vitro Methods 0.000 claims 1
- 238000011503 in vivo imaging Methods 0.000 claims 1
- 125000005647 linker group Chemical group 0.000 claims 1
- 239000000203 mixture Substances 0.000 claims 1
- 210000004898 n-terminal fragment Anatomy 0.000 claims 1
- 230000011664 signaling Effects 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US10/917,326 US7575738B2 (en) | 2004-08-13 | 2004-08-13 | Heat shock protein as a targeting agent for endothelium-specific in vivo transduction |
| PCT/US2005/028491 WO2006020743A2 (en) | 2004-08-13 | 2005-08-11 | Heat shock protein as a targeting agent for endothelium-specific in vivo transduction |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2008509921A JP2008509921A (ja) | 2008-04-03 |
| JP2008509921A5 true JP2008509921A5 (https=) | 2008-09-18 |
Family
ID=35431037
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007525779A Pending JP2008509921A (ja) | 2004-08-13 | 2005-08-11 | 内皮特異的な生体内伝達のターゲティング剤としての熱ショックタンパク質 |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US7575738B2 (https=) |
| EP (1) | EP1776144A2 (https=) |
| JP (1) | JP2008509921A (https=) |
| CN (1) | CN101039702A (https=) |
| WO (1) | WO2006020743A2 (https=) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0610395D0 (en) * | 2006-05-25 | 2006-07-05 | Ge Healthcare Ltd | Novel imaging agents |
| GB0811856D0 (en) | 2008-06-27 | 2008-07-30 | Ucl Business Plc | Magnetic microbubbles, methods of preparing them and their uses |
| US8440167B2 (en) * | 2008-10-27 | 2013-05-14 | University Of Virginia Patent Foundation | Multimodal imaging of atherosclerotic plaque targeted to LOX-1 |
| WO2011045734A1 (en) | 2009-10-16 | 2011-04-21 | Koninklijke Philips Electronics N.V. | Photoacoustic contrast agent based active ultrasound imaging |
| GB201102189D0 (en) * | 2011-02-08 | 2011-03-23 | King S College London | Materials and methods relating to cardiovascular imaging |
| JP6410339B2 (ja) * | 2013-03-25 | 2018-10-24 | 国立大学法人千葉大学 | 放射性核種標識オクトレオチド誘導体 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5175343A (en) * | 1985-01-14 | 1992-12-29 | Neorx Corporation | Metal radionuclide labeled proteins for diagnosis and therapy |
| US4752141A (en) | 1985-10-25 | 1988-06-21 | Luxtron Corporation | Fiberoptic sensing of temperature and/or other physical parameters |
| US4986671A (en) | 1989-04-12 | 1991-01-22 | Luxtron Corporation | Three-parameter optical fiber sensor and system |
| US5275594A (en) | 1990-11-09 | 1994-01-04 | C. R. Bard, Inc. | Angioplasty system having means for identification of atherosclerotic plaque |
| US5217456A (en) | 1992-02-24 | 1993-06-08 | Pdt Cardiovascular, Inc. | Device and method for intra-vascular optical radial imaging |
| WO1999048914A1 (en) * | 1998-03-26 | 1999-09-30 | The University Of New Mexico | Methods for using heat shock proteins |
| DK1133517T3 (da) * | 1998-11-24 | 2009-11-23 | Bristol Myers Squibb Co | Intranuklear målrettet transport af forbindelser ved hjælp af 70 kd varmeshock-protein |
| AU2002254000A1 (en) | 2001-02-23 | 2002-09-12 | Bristol-Myers Squibb Pharma Company | Labeled macrophage scavenger receptor antagonists for imaging atherosclerosis and vulnerable plaque |
| US20040071656A1 (en) * | 2001-12-26 | 2004-04-15 | Felix Wieland | Modulation of heat-shock-protein-based immunotherapies |
| US20050089471A1 (en) * | 2003-10-24 | 2005-04-28 | Johnson Bruce F. | Labeled ligands for lectin-like oxidized low-density lipoprotein receptor (LOX-1) |
-
2004
- 2004-08-13 US US10/917,326 patent/US7575738B2/en not_active Expired - Fee Related
-
2005
- 2005-08-11 CN CNA2005800351346A patent/CN101039702A/zh active Pending
- 2005-08-11 EP EP05788719A patent/EP1776144A2/en not_active Withdrawn
- 2005-08-11 WO PCT/US2005/028491 patent/WO2006020743A2/en not_active Ceased
- 2005-08-11 JP JP2007525779A patent/JP2008509921A/ja active Pending
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