JP2008509921A - 内皮特異的な生体内伝達のターゲティング剤としての熱ショックタンパク質 - Google Patents

内皮特異的な生体内伝達のターゲティング剤としての熱ショックタンパク質 Download PDF

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Publication number
JP2008509921A
JP2008509921A JP2007525779A JP2007525779A JP2008509921A JP 2008509921 A JP2008509921 A JP 2008509921A JP 2007525779 A JP2007525779 A JP 2007525779A JP 2007525779 A JP2007525779 A JP 2007525779A JP 2008509921 A JP2008509921 A JP 2008509921A
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JP
Japan
Prior art keywords
compound
group
lox
amino acid
imaging
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Pending
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JP2007525779A
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English (en)
Japanese (ja)
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JP2008509921A5 (https=
Inventor
シュド，フェイザル
ツァオ，ミン
トーレス，アンドリュー
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General Electric Co
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General Electric Co
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Application filed by General Electric Co filed Critical General Electric Co
Publication of JP2008509921A publication Critical patent/JP2008509921A/ja
Publication of JP2008509921A5 publication Critical patent/JP2008509921A5/ja
Pending legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B59/00—Introduction of isotopes of elements into organic compounds ; Labelled organic compounds per se
    • C07B59/008—Peptides; Proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/0002—General or multifunctional contrast agents, e.g. chelated agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Virology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • AIDS & HIV (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP2007525779A 2004-08-13 2005-08-11 内皮特異的な生体内伝達のターゲティング剤としての熱ショックタンパク質 Pending JP2008509921A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US10/917,326 US7575738B2 (en) 2004-08-13 2004-08-13 Heat shock protein as a targeting agent for endothelium-specific in vivo transduction
PCT/US2005/028491 WO2006020743A2 (en) 2004-08-13 2005-08-11 Heat shock protein as a targeting agent for endothelium-specific in vivo transduction

Publications (2)

Publication Number Publication Date
JP2008509921A true JP2008509921A (ja) 2008-04-03
JP2008509921A5 JP2008509921A5 (https=) 2008-09-18

Family

ID=35431037

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2007525779A Pending JP2008509921A (ja) 2004-08-13 2005-08-11 内皮特異的な生体内伝達のターゲティング剤としての熱ショックタンパク質

Country Status (5)

Country Link
US (1) US7575738B2 (https=)
EP (1) EP1776144A2 (https=)
JP (1) JP2008509921A (https=)
CN (1) CN101039702A (https=)
WO (1) WO2006020743A2 (https=)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2014508147A (ja) * 2011-02-08 2014-04-03 キングス・カレッジ・ロンドン 心血管イメージングに関連する材料および方法
JP2015086213A (ja) * 2013-03-25 2015-05-07 国立大学法人 千葉大学 放射性核種標識オクトレオチド誘導体

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0610395D0 (en) * 2006-05-25 2006-07-05 Ge Healthcare Ltd Novel imaging agents
GB0811856D0 (en) 2008-06-27 2008-07-30 Ucl Business Plc Magnetic microbubbles, methods of preparing them and their uses
US8440167B2 (en) * 2008-10-27 2013-05-14 University Of Virginia Patent Foundation Multimodal imaging of atherosclerotic plaque targeted to LOX-1
EP2488097B1 (en) 2009-10-16 2021-01-13 Koninklijke Philips N.V. Photoacoustic contrast agent based active ultrasound imaging

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999048914A1 (en) * 1998-03-26 1999-09-30 The University Of New Mexico Methods for using heat shock proteins

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5175343A (en) * 1985-01-14 1992-12-29 Neorx Corporation Metal radionuclide labeled proteins for diagnosis and therapy
US4752141A (en) 1985-10-25 1988-06-21 Luxtron Corporation Fiberoptic sensing of temperature and/or other physical parameters
US4986671A (en) 1989-04-12 1991-01-22 Luxtron Corporation Three-parameter optical fiber sensor and system
US5275594A (en) 1990-11-09 1994-01-04 C. R. Bard, Inc. Angioplasty system having means for identification of atherosclerotic plaque
US5217456A (en) 1992-02-24 1993-06-08 Pdt Cardiovascular, Inc. Device and method for intra-vascular optical radial imaging
DE69941156D1 (de) * 1998-11-24 2009-09-03 Bristol Myers Squibb Co Intranukleärer, gerichteter transport von verbindungen durch das 70kd-hitzeschockprotein
EP1377321A4 (en) 2001-02-23 2006-01-11 Bristol Myers Squibb Co RECOVERY ANTAGONISTS RECEIVING DETECTABLE MACROPHAGE RECEPTORS FOR THE IDENTIFICATION OF ATHEROSCLEROSIS AND VULNERABLE PLAQUE BY IMAGING
US20040071656A1 (en) * 2001-12-26 2004-04-15 Felix Wieland Modulation of heat-shock-protein-based immunotherapies
US20050089471A1 (en) * 2003-10-24 2005-04-28 Johnson Bruce F. Labeled ligands for lectin-like oxidized low-density lipoprotein receptor (LOX-1)

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999048914A1 (en) * 1998-03-26 1999-09-30 The University Of New Mexico Methods for using heat shock proteins

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2014508147A (ja) * 2011-02-08 2014-04-03 キングス・カレッジ・ロンドン 心血管イメージングに関連する材料および方法
JP2015086213A (ja) * 2013-03-25 2015-05-07 国立大学法人 千葉大学 放射性核種標識オクトレオチド誘導体

Also Published As

Publication number Publication date
EP1776144A2 (en) 2007-04-25
WO2006020743A2 (en) 2006-02-23
US7575738B2 (en) 2009-08-18
US20060034761A1 (en) 2006-02-16
CN101039702A (zh) 2007-09-19
WO2006020743A3 (en) 2006-07-20

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