EA200971130A1 - Агонисты гуанилатциклазы, пригодные для лечения желудочно-кишечных нарушений, воспаления, рака и других заболеваний - Google Patents

Агонисты гуанилатциклазы, пригодные для лечения желудочно-кишечных нарушений, воспаления, рака и других заболеваний

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Publication number
EA200971130A1
EA200971130A1 EA200971130A EA200971130A EA200971130A1 EA 200971130 A1 EA200971130 A1 EA 200971130A1 EA 200971130 A EA200971130 A EA 200971130A EA 200971130 A EA200971130 A EA 200971130A EA 200971130 A1 EA200971130 A1 EA 200971130A1
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Eurasian Patent Office
Prior art keywords
cancer
diseases
inflammation
treatment
disease
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EA200971130A
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English (en)
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EA020466B1 (ru
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Кунвар Шайлубхай
Гэри С. Джейкоб
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Синерджи Фармасьютикалз Инк.
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Publication of EA200971130A1 publication Critical patent/EA200971130A1/ru
Publication of EA020466B1 publication Critical patent/EA020466B1/ru

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Abstract

Настоящее изобретение относится к новым пептидным агонистам гуанилатциклазы С и к их применению для лечения заболеваний человека, включающих желудочно-кишечные заболевания, воспаление или рак (например, рак желудочно-кишечного тракта). Пептиды можно вводить отдельно или в комбинации с ингибитором cGMP-зависимой фосфодиэстеразы. Желудочно-кишечное заболевание может включать синдром раздраженного кишечника, констипацию, избыточную кислотность и др. Желудочно-кишечное заболевание может включать воспалительное заболевание кишечника или другое состояние ЖК, включая болезнь Крона и язвенный колит, а также рак.
EA200971130A 2007-06-04 2008-06-04 Агонисты гуанилатциклазы, пригодные для лечения желудочно-кишечных нарушений, воспаления, рака и других заболеваний EA020466B1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US93319407P 2007-06-04 2007-06-04
PCT/US2008/065824 WO2008151257A2 (en) 2007-06-04 2008-06-04 Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders

Publications (2)

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EA200971130A1 true EA200971130A1 (ru) 2010-06-30
EA020466B1 EA020466B1 (ru) 2014-11-28

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EA200971130A EA020466B1 (ru) 2007-06-04 2008-06-04 Агонисты гуанилатциклазы, пригодные для лечения желудочно-кишечных нарушений, воспаления, рака и других заболеваний

Country Status (13)

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US (11) US7879802B2 (ru)
EP (3) EP2998314B1 (ru)
JP (3) JP5546451B2 (ru)
CN (2) CN103601792B (ru)
AU (1) AU2008261102B2 (ru)
CA (2) CA3089569C (ru)
DK (1) DK2170930T3 (ru)
EA (1) EA020466B1 (ru)
ES (2) ES2559319T3 (ru)
HK (2) HK1142085A1 (ru)
IL (2) IL202510A (ru)
MX (2) MX354786B (ru)
WO (1) WO2008151257A2 (ru)

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