ATE447417T1 - Konjugate von angiotensin-peptid analoga und chelatbildner für diagnose und therapie - Google Patents

Konjugate von angiotensin-peptid analoga und chelatbildner für diagnose und therapie

Info

Publication number
ATE447417T1
ATE447417T1 AT05722089T AT05722089T ATE447417T1 AT E447417 T1 ATE447417 T1 AT E447417T1 AT 05722089 T AT05722089 T AT 05722089T AT 05722089 T AT05722089 T AT 05722089T AT E447417 T1 ATE447417 T1 AT E447417T1
Authority
AT
Austria
Prior art keywords
denotes
analogas
angiotensin
conjugates
peptide
Prior art date
Application number
AT05722089T
Other languages
English (en)
Inventor
Dagfinn Lovhaug
Original Assignee
Ge Healthcare As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ge Healthcare As filed Critical Ge Healthcare As
Application granted granted Critical
Publication of ATE447417T1 publication Critical patent/ATE447417T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/0497—Organic compounds conjugates with a carrier being an organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
    • A61K47/64—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
    • A61K47/6425—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent the peptide or protein in the drug conjugate being a receptor, e.g. CD4, a cell surface antigen, i.e. not a peptide ligand targeting the antigen, or a cell surface determinant, i.e. a part of the surface of a cell
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
    • A61K47/65—Peptidic linkers, binders or spacers, e.g. peptidic enzyme-labile linkers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/0002—General or multifunctional contrast agents, e.g. chelated agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Optics & Photonics (AREA)
  • Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Hospice & Palliative Care (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AT05722089T 2004-03-04 2005-03-03 Konjugate von angiotensin-peptid analoga und chelatbildner für diagnose und therapie ATE447417T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
NO20040953 2004-03-04
PCT/NO2005/000078 WO2005084715A2 (en) 2004-03-04 2005-03-03 Conjugates of angiotensin peptidic analogues and chelating agents for diagnosis and therapy

Publications (1)

Publication Number Publication Date
ATE447417T1 true ATE447417T1 (de) 2009-11-15

Family

ID=34918859

Family Applications (1)

Application Number Title Priority Date Filing Date
AT05722089T ATE447417T1 (de) 2004-03-04 2005-03-03 Konjugate von angiotensin-peptid analoga und chelatbildner für diagnose und therapie

Country Status (7)

Country Link
US (1) US7763234B2 (de)
EP (1) EP1729823B1 (de)
JP (1) JP2007526300A (de)
CN (1) CN1925876A (de)
AT (1) ATE447417T1 (de)
DE (1) DE602005017475D1 (de)
WO (1) WO2005084715A2 (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0416062D0 (en) * 2004-07-19 2004-08-18 Amersham Plc Improved N4 chelator conjugates
KR101248350B1 (ko) 2004-09-29 2013-04-01 지이 헬스케어 에이에스 ｕＰＡＲ 영상화제
AU2005307195A1 (en) * 2004-11-22 2006-05-26 Ge Healthcare As Contrast agents to target extracellular matrix
WO2010089757A2 (en) * 2008-11-07 2010-08-12 Usv Limited An improved process for synthesis of cyclic octapeptide
TWI587793B (zh) * 2014-02-27 2017-06-21 長庚醫療財團法人基隆長庚紀念醫院 改善心臟衰竭症狀的營養組合物
WO2019169342A1 (en) 2018-03-01 2019-09-06 Trigemina, Inc. Labeled oxytocin and method of manufacture and use

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3966896A (en) 1974-09-06 1976-06-29 Mallinckrodt, Inc. Radioimmunoassay for plasma renin activity
US4647447A (en) 1981-07-24 1987-03-03 Schering Aktiengesellschaft Diagnostic media
US4687659A (en) 1984-11-13 1987-08-18 Salutar, Inc. Diamide-DTPA-paramagnetic contrast agents for MR imaging
ES2155447T3 (es) 1992-01-03 2001-05-16 Rhomed Inc Aplicaciones farmaceuticas de peptidos-iones metalicos.
WO1998018496A2 (en) * 1996-10-28 1998-05-07 Nycomed Imaging As Contrast agents
KR20000052830A (ko) 1996-10-28 2000-08-25 조오지 디빈센조, 토브 아스 헬지, 에바 요한손 진단/치료제 또는 그와 관련된 개선
US6230777B1 (en) 1999-02-04 2001-05-15 Midmac Systems, Inc. Filter forming and joining apparatus
DE60111733T2 (de) 2000-04-12 2006-05-18 Amersham Health As Integrinbindende peptidderivate
AU2001288847A1 (en) * 2000-09-07 2002-03-22 Biosyntema Inc. Conformationally constrained labeled peptides for imaging and therapy
GB0116815D0 (en) * 2001-07-10 2001-08-29 Nycomed Amersham Plc Improved chelator conjugates
HU230901B1 (hu) 2001-07-10 2019-01-28 Ge Healthcare Limited Peptidalapú vegyületek és ezeket tartalmazó gyógyszerkészítmények
GB0206750D0 (en) 2002-03-22 2002-05-01 Amersham Plc Radiofluorination methods
NO20030115D0 (no) 2003-01-09 2003-01-09 Amersham Health As Kontrastmiddel
WO2005044313A2 (en) 2003-11-06 2005-05-19 Amersham Health As Conjugates of angiotensin ii and an imaging moiety

Also Published As

Publication number Publication date
US20070297979A1 (en) 2007-12-27
DE602005017475D1 (de) 2009-12-17
WO2005084715A2 (en) 2005-09-15
CN1925876A (zh) 2007-03-07
JP2007526300A (ja) 2007-09-13
US7763234B2 (en) 2010-07-27
EP1729823A2 (de) 2006-12-13
EP1729823B1 (de) 2009-11-04
WO2005084715A3 (en) 2006-06-15

Similar Documents

Publication Publication Date Title
ATE447417T1 (de) Konjugate von angiotensin-peptid analoga und chelatbildner für diagnose und therapie
SG149895A1 (en) Contrast agents for myocardial perfusion imaging
IL180896A0 (en) Method of tumour imaging
SG152254A1 (en) Contrast agents for myocardial perfusion imaging
ATE439868T1 (de) Targetingmittel für molekulare bilderzeugung
DE69922261D1 (de) Monoklonale antikörper, antigene sowie diagnose und therapie von bösartigen krankheiten
HUP0301020A2 (hu) Konformációs betegségek korai diagnosztikája
GB0326546D0 (en) Inhibitor imaging agents
TNSN07401A1 (fr) Anticorps diriges contre le peptide amyloide-beta, et methodes pour leurs utilisations
MA28153A1 (fr) Acides nucléiques se liant spécifiquement à la ghréline biologiquement active
EP1372741A4 (de) Morpholinobildgebung und therapie
DE50209802D1 (de) Naht-set für medizinische zwecke
NO20072120L (no) Enzyme Inhibitor Imaging Agents
EA200300507A1 (ru) Радиофармацевтические агенты для диагностики болезни альцгеймера
DE502004005226D1 (de) Diagnosestellung von akuten myokardialen, ischämischen erkrankungen durch kombination von markern
DE602007001467D1 (de) Therapeutische Zubereitung von hochreinem FVIIa und Verfahren zu dessen Gewinnung
ATE272074T1 (de) An neuropeptide gebundenes rgd (arg-gly-asp)
EP2340845A3 (de) Wiederholungssequenzen des Ca125-Gens und ihre Verwendung bei diagnostischen und therapeutischen Eingriffen
ATE425770T1 (de) Kontrastmittel
DE60014064D1 (de) Einetenascin-c isoform als marker für neoplasmen
ATE289612T1 (de) Diagnostische verwendungen von gegen acetylcholinesterase oder deren c-terminale peptide gerichteten antikörpern
DE60033697D1 (de) Radiomarkierte vip-analoge zur diagnose und therapie
ATE554790T1 (de) Verfahren und zusammensetzungen zur diagnose von asthma
ATE360212T1 (de) Verfahren zur diagnose der effektivität der xenotypischen antikörpertherapie
MX2021011319A (es) Metodos para el diagnostico de cancer de pulmon.

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties