DE602005017475D1 - Konjugate von angiotensin-peptid analoga und chelatbildner für diagnose und therapie - Google Patents
Konjugate von angiotensin-peptid analoga und chelatbildner für diagnose und therapieInfo
- Publication number
- DE602005017475D1 DE602005017475D1 DE602005017475T DE602005017475T DE602005017475D1 DE 602005017475 D1 DE602005017475 D1 DE 602005017475D1 DE 602005017475 T DE602005017475 T DE 602005017475T DE 602005017475 T DE602005017475 T DE 602005017475T DE 602005017475 D1 DE602005017475 D1 DE 602005017475D1
- Authority
- DE
- Germany
- Prior art keywords
- denotes
- arg
- chelates
- conjugates
- diagnosis
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/0497—Organic compounds conjugates with a carrier being an organic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
- A61K47/64—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
- A61K47/6425—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent the peptide or protein in the drug conjugate being a receptor, e.g. CD4, a cell surface antigen, i.e. not a peptide ligand targeting the antigen, or a cell surface determinant, i.e. a part of the surface of a cell
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
- A61K47/65—Peptidic linkers, binders or spacers, e.g. peptidic enzyme-labile linkers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/0002—General or multifunctional contrast agents, e.g. chelated agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Molecular Biology (AREA)
- Immunology (AREA)
- Cell Biology (AREA)
- Physics & Mathematics (AREA)
- Optics & Photonics (AREA)
- Hospice & Palliative Care (AREA)
- Gastroenterology & Hepatology (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
NO20040953 | 2004-03-04 | ||
PCT/NO2005/000078 WO2005084715A2 (en) | 2004-03-04 | 2005-03-03 | Conjugates of angiotensin peptidic analogues and chelating agents for diagnosis and therapy |
Publications (1)
Publication Number | Publication Date |
---|---|
DE602005017475D1 true DE602005017475D1 (de) | 2009-12-17 |
Family
ID=34918859
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE602005017475T Active DE602005017475D1 (de) | 2004-03-04 | 2005-03-03 | Konjugate von angiotensin-peptid analoga und chelatbildner für diagnose und therapie |
Country Status (7)
Country | Link |
---|---|
US (1) | US7763234B2 (de) |
EP (1) | EP1729823B1 (de) |
JP (1) | JP2007526300A (de) |
CN (1) | CN1925876A (de) |
AT (1) | ATE447417T1 (de) |
DE (1) | DE602005017475D1 (de) |
WO (1) | WO2005084715A2 (de) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB0416062D0 (en) * | 2004-07-19 | 2004-08-18 | Amersham Plc | Improved N4 chelator conjugates |
US8568689B1 (en) | 2004-09-29 | 2013-10-29 | Ge Healthcare As | uPAR-targeting contrast agents |
DE602005025911D1 (de) * | 2004-11-22 | 2011-02-24 | Ge Healthcare As | Kontrastmittel für eine extrazelluläre matrix |
WO2010089757A2 (en) * | 2008-11-07 | 2010-08-12 | Usv Limited | An improved process for synthesis of cyclic octapeptide |
US9730916B2 (en) * | 2014-02-27 | 2017-08-15 | Chang Gung Memorial Hospital, Keelung | Nutritional composition and method for improving heart failure |
WO2019169342A1 (en) | 2018-03-01 | 2019-09-06 | Trigemina, Inc. | Labeled oxytocin and method of manufacture and use |
Family Cites Families (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3966896A (en) * | 1974-09-06 | 1976-06-29 | Mallinckrodt, Inc. | Radioimmunoassay for plasma renin activity |
US4647447A (en) | 1981-07-24 | 1987-03-03 | Schering Aktiengesellschaft | Diagnostic media |
US4687659A (en) | 1984-11-13 | 1987-08-18 | Salutar, Inc. | Diamide-DTPA-paramagnetic contrast agents for MR imaging |
ATE197767T1 (de) | 1992-01-03 | 2000-12-15 | Rhomed Inc | Pharmazeutische anwendungen auf der basis von peptid-metall-ionen |
EP0971747B1 (de) * | 1996-10-28 | 2005-12-28 | Amersham Health AS | Kontrastmittel |
DE69735901T2 (de) | 1996-10-28 | 2007-05-10 | Ge Healthcare As | Verbesseringen an oder in verbindung mit diagnostischen/therapeutischen mitteln |
US6230777B1 (en) | 1999-02-04 | 2001-05-15 | Midmac Systems, Inc. | Filter forming and joining apparatus |
NZ521735A (en) | 2000-04-12 | 2004-12-24 | Amersham Health As | Peptide-based compounds, their use as targeting vectors that bind to receptors associated with antiogenesis such as integrin receptors |
AU2001288847A1 (en) | 2000-09-07 | 2002-03-22 | Biosyntema Inc. | Conformationally constrained labeled peptides for imaging and therapy |
KR100932827B1 (ko) | 2001-07-10 | 2009-12-21 | 지이 헬스케어 에이에스 | 펩티드계 화합물 |
GB0116815D0 (en) * | 2001-07-10 | 2001-08-29 | Nycomed Amersham Plc | Improved chelator conjugates |
GB0206750D0 (en) | 2002-03-22 | 2002-05-01 | Amersham Plc | Radiofluorination methods |
NO20030115D0 (no) | 2003-01-09 | 2003-01-09 | Amersham Health As | Kontrastmiddel |
WO2005044313A2 (en) | 2003-11-06 | 2005-05-19 | Amersham Health As | Conjugates of angiotensin ii and an imaging moiety |
-
2005
- 2005-03-03 DE DE602005017475T patent/DE602005017475D1/de active Active
- 2005-03-03 AT AT05722089T patent/ATE447417T1/de not_active IP Right Cessation
- 2005-03-03 US US10/591,047 patent/US7763234B2/en not_active Expired - Fee Related
- 2005-03-03 EP EP05722089A patent/EP1729823B1/de not_active Not-in-force
- 2005-03-03 JP JP2007501740A patent/JP2007526300A/ja active Pending
- 2005-03-03 CN CNA2005800066559A patent/CN1925876A/zh active Pending
- 2005-03-03 WO PCT/NO2005/000078 patent/WO2005084715A2/en not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
CN1925876A (zh) | 2007-03-07 |
WO2005084715A2 (en) | 2005-09-15 |
WO2005084715A3 (en) | 2006-06-15 |
EP1729823A2 (de) | 2006-12-13 |
JP2007526300A (ja) | 2007-09-13 |
US20070297979A1 (en) | 2007-12-27 |
EP1729823B1 (de) | 2009-11-04 |
US7763234B2 (en) | 2010-07-27 |
ATE447417T1 (de) | 2009-11-15 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
DE602005017475D1 (de) | Konjugate von angiotensin-peptid analoga und chelatbildner für diagnose und therapie | |
US11083710B2 (en) | PSMA binding ligand-linker conjugates and methods for using | |
MX348859B (es) | Agentes de contraste para formacion de imagenes por perfusion miocardial. | |
DE69922261D1 (de) | Monoklonale antikörper, antigene sowie diagnose und therapie von bösartigen krankheiten | |
SG152254A1 (en) | Contrast agents for myocardial perfusion imaging | |
HK1107003A1 (en) | Mr imaging method for the discrimination between healthy and tumour tissue | |
ATE439868T1 (de) | Targetingmittel für molekulare bilderzeugung | |
DE60315296D1 (de) | Zell-selektives Abgabe System | |
MA28153A1 (fr) | Acides nucléiques se liant spécifiquement à la ghréline biologiquement active | |
SI1105409T1 (sl) | Zascita endogenih peptidov pred peptidazno ucinkovitostjo s konjugacijo na krvne komponente | |
DE60217090D1 (de) | Amyloid plaque aggregationshemmer und diagnostische bilderzeugungsmittel | |
MA29409B1 (fr) | Anticorps diriges contre le peptide amyloïde -beta, et methodes pour leurs utilisations | |
GB0326546D0 (en) | Inhibitor imaging agents | |
WO2009117041A3 (en) | Use of pyrene to carry peptides across the blood brain barrier | |
MXPA04006517A (es) | Conjugados que comprenden un anticuerpo especifico para el dominio ed-b de fibronectina y sus usos para la deteccion y tratamiento de tumores. | |
ATE415412T1 (de) | Peptide, die atherosklerotische schädigungen binden | |
NO20025064L (no) | RGO koblet til peptider | |
MA27772A1 (fr) | Preparation pharmaceutique orale destinee aux antagonistes de la pompe a protons | |
ATE466595T1 (de) | Verbindungen und methoden für das downregulating der effekte von tgf-beta | |
ATE435657T1 (de) | Therapeutische zubereitung von hochreinem fviia und verfahren zu dessen gewinnung | |
EP2340845A3 (de) | Wiederholungssequenzen des Ca125-Gens und ihre Verwendung bei diagnostischen und therapeutischen Eingriffen | |
WO2002100885A3 (en) | A penta- or tetrapeptide binding to somatostatin receptors and the use of the same | |
ATE425770T1 (de) | Kontrastmittel | |
ATE289612T1 (de) | Diagnostische verwendungen von gegen acetylcholinesterase oder deren c-terminale peptide gerichteten antikörpern | |
WO2005044313A3 (en) | Conjugates of angiotensin ii and an imaging moiety |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition |