ATE435657T1 - Therapeutische zubereitung von hochreinem fviia und verfahren zu dessen gewinnung - Google Patents
Therapeutische zubereitung von hochreinem fviia und verfahren zu dessen gewinnungInfo
- Publication number
- ATE435657T1 ATE435657T1 AT07380021T AT07380021T ATE435657T1 AT E435657 T1 ATE435657 T1 AT E435657T1 AT 07380021 T AT07380021 T AT 07380021T AT 07380021 T AT07380021 T AT 07380021T AT E435657 T1 ATE435657 T1 AT E435657T1
- Authority
- AT
- Austria
- Prior art keywords
- fviia
- obtaining
- therapeutic preparation
- highly pure
- preparation
- Prior art date
Links
- 230000001225 therapeutic effect Effects 0.000 title abstract 3
- 238000000034 method Methods 0.000 title abstract 2
- 102000004169 proteins and genes Human genes 0.000 abstract 2
- 108090000623 proteins and genes Proteins 0.000 abstract 2
- 230000000694 effects Effects 0.000 abstract 1
- 230000002439 hemostatic effect Effects 0.000 abstract 1
- 230000001553 hepatotropic effect Effects 0.000 abstract 1
- 230000010534 mechanism of action Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/36—Blood coagulation or fibrinolysis factors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Hematology (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Immunology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Diabetes (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Epidemiology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ES200600373A ES2257225B1 (es) | 2006-02-17 | 2006-02-17 | Preparacion terapeutica de fviia de muy alta pureza y metodo para su obtencion. |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE435657T1 true ATE435657T1 (de) | 2009-07-15 |
Family
ID=36676691
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT07380021T ATE435657T1 (de) | 2006-02-17 | 2007-02-05 | Therapeutische zubereitung von hochreinem fviia und verfahren zu dessen gewinnung |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US7531513B2 (de) |
| EP (1) | EP1820509B1 (de) |
| JP (1) | JP5196799B2 (de) |
| AT (1) | ATE435657T1 (de) |
| DE (1) | DE602007001467D1 (de) |
| ES (2) | ES2257225B1 (de) |
| PL (1) | PL1820509T3 (de) |
| PT (1) | PT1820509E (de) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BRPI0912087A2 (pt) * | 2008-05-30 | 2015-10-06 | Novo Nordisk Healthcare Ag | método de controlar uma reação de modificação de polipeptídeo |
| US8784803B2 (en) * | 2009-08-28 | 2014-07-22 | Osaka Air Machine Service, Ltd. | Therapeutic agent for liver-related diseases |
| AU2011343813B2 (en) | 2010-12-15 | 2015-05-21 | Takeda Pharmaceutical Company Limited | Eluate collection using conductivity gradient |
| US10245285B2 (en) | 2016-04-28 | 2019-04-02 | Alkahest, Inc. | Blood plasma and plasma fractions as therapy for tumor growth and progression |
| KR20240036720A (ko) | 2016-08-18 | 2024-03-20 | 알카헤스트 인코포레이티드 | 노화-관련된 인지 장애 치료제로서의 혈장 분획 |
| IL270125B2 (en) | 2017-04-26 | 2024-02-01 | Alkahest Inc | Dosing regimen for treatment of cognitive and motor impairments with blood plasma and blood plasma products |
| CN112469424A (zh) | 2018-07-20 | 2021-03-09 | 万能溶剂有限公司 | 用血浆和血浆制品治疗认知障碍和运动障碍的给药方案 |
| EP3870190A4 (de) | 2018-10-26 | 2022-09-07 | Alkahest, Inc. | Verwendung von plasma- und plasmafraktionen zur verbesserung von schmerz, wundheilung und postoperativer erholung |
| JP2022553837A (ja) | 2019-11-04 | 2022-12-26 | アルカヘスト,インコーポレイテッド | 筋肉再生に使用するための血漿画分 |
| CN119215068A (zh) | 2019-11-20 | 2024-12-31 | 万能溶剂有限公司 | 用于肝再生的血浆级分 |
| WO2024200553A1 (en) | 2023-03-29 | 2024-10-03 | Grifols Worldwide Operations Limited | COMPOSITIONS AND METHODS OF PREPARATION OF BLOOD PLASMA PRODUCTS WITH REDUCED LEVELS OF FceRIß AUTOANTIBODIES |
| WO2025230830A1 (en) | 2024-04-29 | 2025-11-06 | Alkahest, Inc. | Compositions of blood plasma fractions and their use in treatment of spinal muscular atrophy (sma) |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4479938A (en) * | 1981-06-25 | 1984-10-30 | Baxter Travenol Laboratories, Inc. | Therapeutic composition containing factor VIIa |
| US4470969A (en) * | 1983-12-02 | 1984-09-11 | Miles Laboratories, Inc. | Process for producing a concentrate of coagulation factors VII and VIIa |
| FR2632524B1 (fr) * | 1988-06-09 | 1992-03-13 | Fondation Nale Transfusion San | Procede de preparation d'une fraction concentree en facteur viia et son application a titre de medicament |
| FR2684999A1 (fr) * | 1991-12-16 | 1993-06-18 | Aquitaine Dev Transf Sanguine | Procede de fabrication d'un concentre de facteur vii active de haute purete essentiellement depourvu des facteurs vitamine k dependants et des facteurs viiic et viiicag. |
| DE19531637A1 (de) * | 1995-08-28 | 1997-03-06 | Immuno Ag | Pharmazeutische Zusammensetzung zur Behandlung von Blutgerinnungsstörugnen, Verfahren zur Herstellung derselben und deren Verwendung |
| US6310183B1 (en) * | 1997-09-10 | 2001-10-30 | Novo Nordisk A/S | Coagulation factor VIIa composition |
| JP2000103800A (ja) * | 1998-09-29 | 2000-04-11 | Yoshitomi Pharmaceut Ind Ltd | 免疫グロブリンaの精製方法 |
| EP1280548B1 (de) * | 2000-05-03 | 2013-12-11 | Novo Nordisk Health Care AG | Subkutane Verabreichung des Koagulationsfaktor VII |
| DE10211632A1 (de) * | 2002-03-15 | 2003-10-09 | Aventis Behring Gmbh | Verfahren zur Abtrennung von Viren aus einer Proteinlösung durch Nanofiltration |
| AU2003240438A1 (en) * | 2002-06-21 | 2004-01-06 | Novo Nordisk A/S | Stabilised solid compositions of factor vii polypeptides |
| EP1713906A2 (de) * | 2004-02-03 | 2006-10-25 | Novo Nordisk Health Care AG | Keine funktionelle lipid-membran-bindungsdomäne aufweisende koagulationsfaktor vii/viia-varianten |
| US20070037966A1 (en) * | 2004-05-04 | 2007-02-15 | Novo Nordisk A/S | Hydrophobic interaction chromatography purification of factor VII polypeptides |
| WO2006011161A2 (en) * | 2004-06-29 | 2006-02-02 | Reliance Life Sciences Pvt Ltd | Process for the preparation of virus-safe biological fluids |
-
2006
- 2006-02-17 ES ES200600373A patent/ES2257225B1/es not_active Expired - Fee Related
-
2007
- 2007-02-05 PL PL07380021T patent/PL1820509T3/pl unknown
- 2007-02-05 AT AT07380021T patent/ATE435657T1/de active
- 2007-02-05 PT PT07380021T patent/PT1820509E/pt unknown
- 2007-02-05 ES ES07380021T patent/ES2327013T3/es active Active
- 2007-02-05 DE DE602007001467T patent/DE602007001467D1/de active Active
- 2007-02-05 EP EP07380021A patent/EP1820509B1/de active Active
- 2007-02-08 US US11/672,838 patent/US7531513B2/en active Active
- 2007-02-16 JP JP2007035673A patent/JP5196799B2/ja not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| US7531513B2 (en) | 2009-05-12 |
| JP2007217415A (ja) | 2007-08-30 |
| PL1820509T3 (pl) | 2009-12-31 |
| PT1820509E (pt) | 2009-09-02 |
| DE602007001467D1 (de) | 2009-08-20 |
| EP1820509B1 (de) | 2009-07-08 |
| ES2257225A1 (es) | 2006-07-16 |
| US20070197440A1 (en) | 2007-08-23 |
| ES2327013T3 (es) | 2009-10-22 |
| ES2257225B1 (es) | 2007-03-16 |
| EP1820509A1 (de) | 2007-08-22 |
| JP5196799B2 (ja) | 2013-05-15 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
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