CY1108689T1 - Ολιγοπεπτιδια για την ελαττωση αυξημενης συγκεντρωσεως της ουριας στο αιμα - Google Patents

Ολιγοπεπτιδια για την ελαττωση αυξημενης συγκεντρωσεως της ουριας στο αιμα

Info

Publication number
CY1108689T1
CY1108689T1 CY20091100001T CY091100001T CY1108689T1 CY 1108689 T1 CY1108689 T1 CY 1108689T1 CY 20091100001 T CY20091100001 T CY 20091100001T CY 091100001 T CY091100001 T CY 091100001T CY 1108689 T1 CY1108689 T1 CY 1108689T1
Authority
CY
Cyprus
Prior art keywords
oligopeptides
blood
seq
urine concentration
subject
Prior art date
Application number
CY20091100001T
Other languages
English (en)
Inventor
Nisar Ahmed Khan
Robbert Benner
Original Assignee
Biotempt B.V.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biotempt B.V. filed Critical Biotempt B.V.
Publication of CY1108689T1 publication Critical patent/CY1108689T1/el

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/06—Tripeptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/07—Tetrapeptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Urology & Nephrology (AREA)
  • Nutrition Science (AREA)
  • Dermatology (AREA)
  • Physiology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Materials For Medical Uses (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Η εφεύρεση περιλαμβάνει μέθοδο για την ελάττωση της συγκεντρώσεως της ουρίας στον ορό εξεταζόμενου. Αυτή η μέθοδος περιλαμβάνει τη χορήγηση στον εξεταζόμενο (π.χ. θηλαστικό όπως άνθρωπος) μίας σύνθεσης που περιλαμβάνει ολιγοπεπτίδιο (ή ολιγοπεπτίδια) που εμφανίζει ενεργότητα ελάττωσης της συγκεντρώσεως ουρίας στον ορό του εξεταζόμενου, όπως προσδιορίζεται μέσω της εξέτασης νεφρικής επαναιμάτωσης ποντικού, το δε ολιγοπεπτίδιο περιλαμβάνει την αλληλουχία QGV ή MTRV (SEQ ID ΝΟ:1) (π.χ. AQGV (SEQ ID ΝΟ:2) ή MTRV (SEQ ID ΝΟ:1)).
CY20091100001T 2004-04-08 2009-01-07 Ολιγοπεπτιδια για την ελαττωση αυξημενης συγκεντρωσεως της ουριας στο αιμα CY1108689T1 (el)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US10/821,256 US20050227925A1 (en) 2004-04-08 2004-04-08 Compositions capable of reducing elevated blood urea concentration
EP05729655A EP1755634B1 (en) 2004-04-08 2005-04-08 Oligopeptides for reducing elevated blood urea concentration

Publications (1)

Publication Number Publication Date
CY1108689T1 true CY1108689T1 (el) 2014-04-09

Family

ID=34963497

Family Applications (1)

Application Number Title Priority Date Filing Date
CY20091100001T CY1108689T1 (el) 2004-04-08 2009-01-07 Ολιγοπεπτιδια για την ελαττωση αυξημενης συγκεντρωσεως της ουριας στο αιμα

Country Status (21)

Country Link
US (2) US20050227925A1 (el)
EP (1) EP1755634B1 (el)
JP (1) JP4732438B2 (el)
KR (1) KR101217025B1 (el)
CN (1) CN101014356B (el)
AT (1) ATE410178T1 (el)
AU (1) AU2005230403B2 (el)
CA (1) CA2561833C (el)
CY (1) CY1108689T1 (el)
DE (1) DE602005010246D1 (el)
DK (1) DK1755634T3 (el)
ES (1) ES2315858T3 (el)
HK (1) HK1107030A1 (el)
HR (1) HRP20090003T3 (el)
IL (1) IL178515A (el)
NZ (1) NZ550574A (el)
PL (1) PL1755634T3 (el)
PT (1) PT1755634E (el)
RS (1) RS50727B (el)
SI (1) SI1755634T1 (el)
WO (1) WO2005097163A1 (el)

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US6921751B1 (en) 1998-05-20 2005-07-26 Erasmus Universiteit Rotterdam Immunoregulator
US8680059B2 (en) * 1998-05-20 2014-03-25 Biotempt B.V. Oligopeptide acetate and formulations thereof
US20040202645A1 (en) * 2003-04-08 2004-10-14 Khan Nisar Ahmed Administration of gene-regulatory peptides
US20030220258A1 (en) 2001-12-21 2003-11-27 Robbert Benner Treatment of ischemic events
US20050227925A1 (en) * 2004-04-08 2005-10-13 Robbert Benner Compositions capable of reducing elevated blood urea concentration
US6844315B2 (en) 1998-05-20 2005-01-18 Erasmus Universiteit Rotterdam Immunoregulator
EP1300418A1 (en) * 2001-10-04 2003-04-09 Erasmus Universiteit Rotterdam Gene regulation by oligopeptides
US7358330B2 (en) * 2001-03-29 2008-04-15 Biotempt B.V. Immunoregulatory compositions
USRE43279E1 (en) 2000-03-29 2012-03-27 Biotemp B.V. Compositions capable of reducing elevated blood urea concentration
US20030220259A1 (en) * 2001-12-21 2003-11-27 Robbert Benner Treatment of neurological disorders
US20030220260A1 (en) * 2001-12-21 2003-11-27 Khan Nisar Ahmed Peptide compositions
US7501391B2 (en) * 2001-12-21 2009-03-10 Biotempt B.V. Treatment of transplant survival
US20040013661A1 (en) * 2001-12-21 2004-01-22 Gert Wensvoort Stratification
US20080318871A1 (en) * 2001-12-21 2008-12-25 Khan Nisar A Treatment of neurological disorders
US20030220261A1 (en) * 2001-12-21 2003-11-27 Khan Nisar Ahmed Treatment of iatrogenic disease
US20030220257A1 (en) * 2001-12-21 2003-11-27 Robbert Benner Treatment of trauma
US7560433B2 (en) * 2001-12-21 2009-07-14 Biotempt B.V. Treatment of multiple sclerosis (MS)
US7786084B2 (en) * 2001-12-21 2010-08-31 Biotempt B.V. Treatment of burns
US20080242837A1 (en) * 2001-12-21 2008-10-02 Khan Nisar A Peptide compositions
US20030224995A1 (en) * 2001-12-21 2003-12-04 Khan Nisar Ahmed Treatment of burns
US20090227505A1 (en) * 2004-01-07 2009-09-10 Biotempt B.V. Methods and uses for protein breakdown products
WO2007004869A2 (en) * 2005-07-05 2007-01-11 Biotempt B.V. Treatment of tumors
DE102005045152A1 (de) * 2005-09-21 2007-03-22 Stremmel, Wolfgang, Prof. Dr. Verwendung von therapeutisch wirksamen Lipiden nebst Verfahren zur Herstellung von Organ-/Gewebe-spezifischen therapeutisch wirksamen Lipiden
EP1864692A1 (en) * 2006-06-07 2007-12-12 Biotempt B.V. Use of peptides for the control of radiation injury
CN101443080B (zh) * 2006-03-07 2015-01-14 比奥滕普特公司 肽在控制辐射损伤中的用途
NZ578956A (en) * 2007-02-12 2012-02-24 Biotempt Bv Treatment of trauma hemorrhage with short oligopeptides
WO2009014440A1 (en) * 2007-07-23 2009-01-29 Biotempt B.V. Inhibition of renal ischemia reperfusion injury by synthetic oligopeptides
CN113499349B (zh) * 2021-07-13 2023-11-21 西南民族大学 一种慢性肾功能衰竭治疗用爬沙虫提取物及其制备方法和应用

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Also Published As

Publication number Publication date
KR20070036029A (ko) 2007-04-02
DE602005010246D1 (de) 2008-11-20
RS50727B (sr) 2010-08-31
ES2315858T3 (es) 2009-04-01
HRP20090003T3 (en) 2009-02-28
AU2005230403A1 (en) 2005-10-20
IL178515A (en) 2011-12-29
CN101014356B (zh) 2012-06-13
WO2005097163A1 (en) 2005-10-20
HK1107030A1 (en) 2008-03-28
SI1755634T1 (sl) 2009-04-30
CN101014356A (zh) 2007-08-08
AU2005230403B2 (en) 2009-05-21
IL178515A0 (en) 2007-02-11
NZ550574A (en) 2008-08-29
CA2561833C (en) 2014-05-27
JP4732438B2 (ja) 2011-07-27
PL1755634T3 (pl) 2009-03-31
PT1755634E (pt) 2009-01-15
US20050227925A1 (en) 2005-10-13
DK1755634T3 (da) 2009-02-16
EP1755634A1 (en) 2007-02-28
CA2561833A1 (en) 2005-10-20
EP1755634B1 (en) 2008-10-08
ATE410178T1 (de) 2008-10-15
JP2007532510A (ja) 2007-11-15
US20060142205A1 (en) 2006-06-29
KR101217025B1 (ko) 2013-01-02

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