DE60014064D1 - Einetenascin-c isoform als marker für neoplasmen - Google Patents
Einetenascin-c isoform als marker für neoplasmenInfo
- Publication number
- DE60014064D1 DE60014064D1 DE60014064T DE60014064T DE60014064D1 DE 60014064 D1 DE60014064 D1 DE 60014064D1 DE 60014064 T DE60014064 T DE 60014064T DE 60014064 T DE60014064 T DE 60014064T DE 60014064 D1 DE60014064 D1 DE 60014064D1
- Authority
- DE
- Germany
- Prior art keywords
- isoform
- einetenascin
- neoplasms
- marker
- ctn
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6887—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids from muscle, cartilage or connective tissue
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/60—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
- C07K2317/62—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
- C07K2317/622—Single chain antibody (scFv)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ITFI990094 | 1999-04-20 | ||
IT1999FI000094A IT1307864B1 (it) | 1999-04-20 | 1999-04-20 | Metodo diagnostico per il riconoscimento di neoplasie umane attraversola determinazione dell'isoforma ctn-c della tn-c, frammenti di |
PCT/EP2000/003550 WO2000063699A1 (en) | 1999-04-20 | 2000-04-19 | A tenascin-c isoform as a marker for neoplasias |
Publications (2)
Publication Number | Publication Date |
---|---|
DE60014064D1 true DE60014064D1 (de) | 2004-10-28 |
DE60014064T2 DE60014064T2 (de) | 2006-02-23 |
Family
ID=11352932
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE60014064T Expired - Lifetime DE60014064T2 (de) | 1999-04-20 | 2000-04-19 | Einetenascin-c isoform als marker für neoplasmen |
Country Status (11)
Country | Link |
---|---|
US (1) | US7109301B1 (de) |
EP (1) | EP1173766B1 (de) |
JP (1) | JP4577665B2 (de) |
AT (1) | ATE277352T1 (de) |
AU (1) | AU779015B2 (de) |
CA (1) | CA2370666C (de) |
DE (1) | DE60014064T2 (de) |
DK (1) | DK1173766T3 (de) |
ES (1) | ES2226823T3 (de) |
IT (1) | IT1307864B1 (de) |
WO (1) | WO2000063699A1 (de) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IT1317108B1 (it) * | 2000-12-06 | 2003-05-26 | Philogen Srl | Processo per la selezione di frammenti anticorporali anti-angiogenesi,frammenti anticorpali anti-angiogenesi cosi' ottenuti e loro uso. |
CA2446734A1 (en) * | 2001-05-24 | 2002-11-28 | Human Genome Sciences, Inc. | Antibodies against tumor necrosis factor delta (april) |
EP1446416A4 (de) * | 2001-11-19 | 2005-11-30 | Applied Molecular Evolution | Tumorspezifische monoklonale antikörper |
DE602005014665D1 (de) * | 2004-11-09 | 2009-07-09 | Philogen Spa | Antikörper gegen tenascin-c |
LT2757091T (lt) | 2008-04-01 | 2017-09-11 | Biosearch Technologies, Inc. | Stabilizuotos nukleorūgšties tamsūs kvenčerio-fluoroforo zondai |
BR112013002444A2 (pt) | 2010-08-13 | 2016-05-24 | Roche Glycart Ag | anticorpo, polinucleotídeo e polipeotídeo isolados, composição, vetor, cécula hospedeira, conjulgado de anticorpo, formulação farmacêutica, uso do anticorpo, métodos para produzir um anticorpo, tratar um indivíduo, induzir a lise celular de uma célula tumorosa e diagnosticar uma doença em um indivíduo |
WO2017194442A1 (en) | 2016-05-11 | 2017-11-16 | F. Hoffmann-La Roche Ag | Antigen binding molecules comprising a tnf family ligand trimer and a tenascin binding moiety |
EP3455252B1 (de) * | 2016-05-11 | 2022-02-23 | F. Hoffmann-La Roche AG | Modifizierte anti-tenascin-antikörper und verfahren zur verwendung |
GB201621806D0 (en) | 2016-12-21 | 2017-02-01 | Philogen Spa | Immunocytokines with progressive activation mechanism |
CN110382542B (zh) | 2017-03-29 | 2023-06-09 | 豪夫迈·罗氏有限公司 | 针对共刺激性tnf受体的双特异性抗原结合分子 |
CN107058596A (zh) * | 2017-06-19 | 2017-08-18 | 上海市第十人民医院 | 一种与恶性胶质瘤诊断相关的标志物及其应用 |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU8547291A (en) * | 1990-09-05 | 1992-03-30 | Wistar Institute, The | Monoclonal antibodies against tenascin |
JPH0643167A (ja) * | 1992-04-06 | 1994-02-18 | Amano Pharmaceut Co Ltd | 癌マーカーであるテネイシン及びその定量法 |
HU220347B (hu) * | 1994-07-11 | 2001-12-28 | Board Of Regents The University Of Texas System | Készítmény az érrendszer specifikus koagulálásához |
JPH10505750A (ja) * | 1994-09-16 | 1998-06-09 | ザ スクリップス リサーチ インスティテュート | 粘着および軸索の成長を刺激するサイトタクチン誘導体並びにその製造および使用方法 |
JP3850492B2 (ja) * | 1996-08-23 | 2006-11-29 | 独立行政法人理化学研究所 | テネイシン誘導因子 |
-
1999
- 1999-04-20 IT IT1999FI000094A patent/IT1307864B1/it active
-
2000
- 2000-04-19 EP EP00925224A patent/EP1173766B1/de not_active Expired - Lifetime
- 2000-04-19 CA CA2370666A patent/CA2370666C/en not_active Expired - Fee Related
- 2000-04-19 DE DE60014064T patent/DE60014064T2/de not_active Expired - Lifetime
- 2000-04-19 US US09/959,373 patent/US7109301B1/en not_active Expired - Fee Related
- 2000-04-19 DK DK00925224T patent/DK1173766T3/da active
- 2000-04-19 AU AU44015/00A patent/AU779015B2/en not_active Ceased
- 2000-04-19 JP JP2000612753A patent/JP4577665B2/ja not_active Expired - Fee Related
- 2000-04-19 ES ES00925224T patent/ES2226823T3/es not_active Expired - Lifetime
- 2000-04-19 WO PCT/EP2000/003550 patent/WO2000063699A1/en active IP Right Grant
- 2000-04-19 AT AT00925224T patent/ATE277352T1/de not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
AU4401500A (en) | 2000-11-02 |
CA2370666C (en) | 2010-06-01 |
DK1173766T3 (da) | 2005-01-31 |
CA2370666A1 (en) | 2000-10-26 |
DE60014064T2 (de) | 2006-02-23 |
EP1173766A1 (de) | 2002-01-23 |
ES2226823T3 (es) | 2005-04-01 |
US7109301B1 (en) | 2006-09-19 |
ATE277352T1 (de) | 2004-10-15 |
IT1307864B1 (it) | 2001-11-19 |
WO2000063699A1 (en) | 2000-10-26 |
AU779015B2 (en) | 2005-01-06 |
EP1173766B1 (de) | 2004-09-22 |
JP2002542486A (ja) | 2002-12-10 |
JP4577665B2 (ja) | 2010-11-10 |
ITFI990094A1 (it) | 2000-10-20 |
ITFI990094A0 (it) | 1999-04-20 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition |