ATE277352T1 - Einetenascin-c isoform als marker für neoplasmen - Google Patents

Einetenascin-c isoform als marker für neoplasmen

Info

Publication number
ATE277352T1
ATE277352T1 AT00925224T AT00925224T ATE277352T1 AT E277352 T1 ATE277352 T1 AT E277352T1 AT 00925224 T AT00925224 T AT 00925224T AT 00925224 T AT00925224 T AT 00925224T AT E277352 T1 ATE277352 T1 AT E277352T1
Authority
AT
Austria
Prior art keywords
isoform
eintenascin
neoplasms
marker
ctn
Prior art date
Application number
AT00925224T
Other languages
English (en)
Inventor
Luciano Zardi
Original Assignee
Philogen Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Philogen Spa filed Critical Philogen Spa
Application granted granted Critical
Publication of ATE277352T1 publication Critical patent/ATE277352T1/de

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6887—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids from muscle, cartilage or connective tissue
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • G01N33/575—
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/60—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
    • C07K2317/62—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
    • C07K2317/622—Single chain antibody (scFv)

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Urology & Nephrology (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Analytical Chemistry (AREA)
  • Biotechnology (AREA)
  • Food Science & Technology (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Physics & Mathematics (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Magnetic Resonance Imaging Apparatus (AREA)
  • Apparatus For Radiation Diagnosis (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Steroid Compounds (AREA)
AT00925224T 1999-04-20 2000-04-19 Einetenascin-c isoform als marker für neoplasmen ATE277352T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT1999FI000094A IT1307864B1 (it) 1999-04-20 1999-04-20 Metodo diagnostico per il riconoscimento di neoplasie umane attraversola determinazione dell'isoforma ctn-c della tn-c, frammenti di
PCT/EP2000/003550 WO2000063699A1 (en) 1999-04-20 2000-04-19 A tenascin-c isoform as a marker for neoplasias

Publications (1)

Publication Number Publication Date
ATE277352T1 true ATE277352T1 (de) 2004-10-15

Family

ID=11352932

Family Applications (1)

Application Number Title Priority Date Filing Date
AT00925224T ATE277352T1 (de) 1999-04-20 2000-04-19 Einetenascin-c isoform als marker für neoplasmen

Country Status (11)

Country Link
US (1) US7109301B1 (de)
EP (1) EP1173766B1 (de)
JP (1) JP4577665B2 (de)
AT (1) ATE277352T1 (de)
AU (1) AU779015B2 (de)
CA (1) CA2370666C (de)
DE (1) DE60014064T2 (de)
DK (1) DK1173766T3 (de)
ES (1) ES2226823T3 (de)
IT (1) IT1307864B1 (de)
WO (1) WO2000063699A1 (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1317108B1 (it) * 2000-12-06 2003-05-26 Philogen Srl Processo per la selezione di frammenti anticorporali anti-angiogenesi,frammenti anticorpali anti-angiogenesi cosi' ottenuti e loro uso.
AU2002311976A1 (en) * 2001-05-24 2002-12-03 Human Genome Sciences, Inc. Antibodies against tumor necrosis factor delta (april)
JP2005517388A (ja) * 2001-11-19 2005-06-16 アプライド モレキュラー エボリューション，インコーポレイテッド 腫瘍特異的モノクローナル抗体
KR20070085892A (ko) * 2004-11-09 2007-08-27 필로겐 에스.피.에이. 테나신-ｃ에 대한 항체
MX2010010881A (es) 2008-04-01 2011-03-04 Biosearch Tech Inc Sondas oscuras apagadoras de fluoroforo de acido nucleico estabilizado.
EP2603529A1 (de) 2010-08-13 2013-06-19 Roche Glycart AG Anti-tenascin-c-a2-antikörper und verwendungsverfahren dafür
WO2017194441A1 (en) 2016-05-11 2017-11-16 F. Hoffmann-La Roche Ag Modified anti-tenascin antibodies and methods of use
EP3455254B1 (de) 2016-05-11 2021-07-07 F. Hoffmann-La Roche AG Antigenbindende moleküle mit einem ligandentrimer der tnf-familie und einem tenascin-bindungsteil
GB201621806D0 (en) 2016-12-21 2017-02-01 Philogen Spa Immunocytokines with progressive activation mechanism
JP7205995B2 (ja) 2017-03-29 2023-01-17 エフ・ホフマン－ラ・ロシュ・アクチェンゲゼルシャフト 共刺激性ｔｎｆ受容体に対する二重特異性抗原結合分子
CN107058596A (zh) * 2017-06-19 2017-08-18 上海市第十人民医院 一种与恶性胶质瘤诊断相关的标志物及其应用

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU8547291A (en) * 1990-09-05 1992-03-30 Wistar Institute, The Monoclonal antibodies against tenascin
JPH0643167A (ja) * 1992-04-06 1994-02-18 Amano Pharmaceut Co Ltd 癌マーカーであるテネイシン及びその定量法
EP0771216B9 (de) * 1994-07-11 2003-01-02 The Board Of Regents, The University Of Texas System Verfahren und zusammensetzungen für die spezifische koagulation von tumorgefässen
EP0781297A4 (de) * 1994-09-16 1999-05-19 Scripps Research Inst Cytotactin-derivate, welche neuronale verbindungen und das neuritenwachstum fördern und verfahren ihrer produktion und anwendung
JP3850492B2 (ja) * 1996-08-23 2006-11-29 独立行政法人理化学研究所 テネイシン誘導因子

Also Published As

Publication number Publication date
ITFI990094A1 (it) 2000-10-20
DE60014064T2 (de) 2006-02-23
CA2370666C (en) 2010-06-01
EP1173766B1 (de) 2004-09-22
CA2370666A1 (en) 2000-10-26
ES2226823T3 (es) 2005-04-01
DK1173766T3 (da) 2005-01-31
AU4401500A (en) 2000-11-02
AU779015B2 (en) 2005-01-06
WO2000063699A1 (en) 2000-10-26
DE60014064D1 (de) 2004-10-28
US7109301B1 (en) 2006-09-19
IT1307864B1 (it) 2001-11-19
ITFI990094A0 (it) 1999-04-20
JP4577665B2 (ja) 2010-11-10
EP1173766A1 (de) 2002-01-23
JP2002542486A (ja) 2002-12-10

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