ATE494913T1 - Kontrastmittel für eine extrazelluläre matrix - Google Patents

Kontrastmittel für eine extrazelluläre matrix

Info

Publication number
ATE494913T1
ATE494913T1 AT05817391T AT05817391T ATE494913T1 AT E494913 T1 ATE494913 T1 AT E494913T1 AT 05817391 T AT05817391 T AT 05817391T AT 05817391 T AT05817391 T AT 05817391T AT E494913 T1 ATE494913 T1 AT E494913T1
Authority
AT
Austria
Prior art keywords
extracellular matrix
contrast agents
biomodifier
areas
human
Prior art date
Application number
AT05817391T
Other languages
English (en)
Inventor
Dagfinn Lyvhaug
Morten Eriksen
Hege B Fjerdingstad
Andrew Healey
Original Assignee
Ge Healthcare As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ge Healthcare As filed Critical Ge Healthcare As
Application granted granted Critical
Publication of ATE494913T1 publication Critical patent/ATE494913T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A61K49/08—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
    • A61K49/10—Organic compounds
    • A61K49/14—Peptides, e.g. proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/001—Preparation for luminescence or biological staining
    • A61K49/0013—Luminescence
    • A61K49/0017—Fluorescence in vivo
    • A61K49/005—Fluorescence in vivo characterised by the carrier molecule carrying the fluorescent agent
    • A61K49/0056—Peptides, proteins, polyamino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/0002—General or multifunctional contrast agents, e.g. chelated agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/001—Preparation for luminescence or biological staining
    • A61K49/0013—Luminescence
    • A61K49/0017—Fluorescence in vivo
    • A61K49/0019—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules
    • A61K49/0021—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules the fluorescent group being a small organic molecule
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/001—Preparation for luminescence or biological staining
    • A61K49/0013—Luminescence
    • A61K49/0017—Fluorescence in vivo
    • A61K49/0019—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules
    • A61K49/0021—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules the fluorescent group being a small organic molecule
    • A61K49/0032—Methine dyes, e.g. cyanine dyes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A61K49/08—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
    • A61K49/085—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier conjugated systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/0497—Organic compounds conjugates with a carrier being an organic compounds

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Radiology & Medical Imaging (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Physics & Mathematics (AREA)
  • Optics & Photonics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Magnetic Resonance Imaging Apparatus (AREA)
  • Steroid Compounds (AREA)
AT05817391T 2004-11-22 2005-11-21 Kontrastmittel für eine extrazelluläre matrix ATE494913T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
NO20045081 2004-11-22
PCT/NO2005/000435 WO2006054904A2 (en) 2004-11-22 2005-11-21 Contrast agents to target extracellular matrix

Publications (1)

Publication Number Publication Date
ATE494913T1 true ATE494913T1 (de) 2011-01-15

Family

ID=36182407

Family Applications (1)

Application Number Title Priority Date Filing Date
AT05817391T ATE494913T1 (de) 2004-11-22 2005-11-21 Kontrastmittel für eine extrazelluläre matrix

Country Status (17)

Country Link
US (1) US8182790B2 (de)
EP (2) EP2243496A3 (de)
JP (2) JP5116480B2 (de)
KR (1) KR20070091609A (de)
CN (1) CN101107016B (de)
AT (1) ATE494913T1 (de)
AU (1) AU2005307195A1 (de)
BR (1) BRPI0518328A2 (de)
CA (1) CA2586621A1 (de)
DE (1) DE602005025911D1 (de)
ES (1) ES2358745T3 (de)
IL (1) IL182898A0 (de)
MX (1) MX2007006050A (de)
NO (1) NO20073039L (de)
RU (1) RU2007118385A (de)
WO (1) WO2006054904A2 (de)
ZA (1) ZA200705043B (de)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0610395D0 (en) * 2006-05-25 2006-07-05 Ge Healthcare Ltd Novel imaging agents
EP2056886A2 (de) * 2006-08-28 2009-05-13 GE Healthcare Limited 68ga-markierte radiopharmazeutika auf peptidbasis
JP2008266194A (ja) * 2007-04-19 2008-11-06 Hiroshi Tanaka 分子プローブの原料として有用な新規有機化合物
GB0722650D0 (en) * 2007-11-19 2007-12-27 Ge Healthcare Ltd Novel imaging method
EP2224959B1 (de) 2007-12-13 2015-02-25 INSERM (Institut National de la Santé et de la Recherche Médicale) Polypeptide, zyklische polypeptide und pharmazeutikum daraus zur nicht-invasiven spezifischen abbildung von fibrose
EP3320923B1 (de) 2008-01-18 2022-04-06 Visen Medical, Inc. Fluoreszierende bildgebungsmittel
KR20140001257A (ko) 2008-05-13 2014-01-06 유니버시티 오브 캔사스 금속 추출 펩타이드(ｍａｐ) 태그 및 관련된 방법
GB0814722D0 (en) * 2008-08-12 2008-09-17 Ge Healthcare Ltd Treatment monitoring
GB0910013D0 (en) * 2009-06-10 2009-07-22 Ge Healthcare Ltd PET imaging of fibogenesis
KR100991716B1 (ko) * 2009-10-22 2010-11-04 경북대학교 산학협력단 광학영상 조영제, 그 용도 및 장치
CN102504603B (zh) * 2011-10-20 2014-01-29 中国海洋大学 一种多聚物与生物染色剂的偶合物及其制备方法和用途
WO2013181461A2 (en) 2012-06-01 2013-12-05 University Of Kansas Metal abstraction peptide with superoxide dismutase activity
CN105939732A (zh) * 2013-12-03 2016-09-14 通用医疗公司 分子成像探针

Family Cites Families (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4647447A (en) 1981-07-24 1987-03-03 Schering Aktiengesellschaft Diagnostic media
US4615876A (en) * 1983-04-25 1986-10-07 Curators Of The University Of Missouri Macrocyclic complexes of technetium-99m for use as diagnostic radionuclides
US4687659A (en) 1984-11-13 1987-08-18 Salutar, Inc. Diamide-DTPA-paramagnetic contrast agents for MR imaging
US5268486A (en) 1986-04-18 1993-12-07 Carnegie-Mellon Unversity Method for labeling and detecting materials employing arylsulfonate cyanine dyes
US6048982A (en) 1986-04-18 2000-04-11 Carnegie Mellon University Cyanine dyes as labeling reagents for detection of biological and other materials by luminescence methods
ATE145337T1 (de) 1988-05-02 1996-12-15 Phanos Tech Inc Verbindungen, zusammensetzungen und verfahren zum binden von bio-affektions-substanzen an oberflächenmembranen von bioteilchen
GB8903022D0 (en) * 1989-02-10 1989-03-30 Celltech Ltd Chemical compounds
WO1993011120A1 (en) 1991-11-27 1993-06-10 Zynaxis Technologies, Incorporated Compounds, compositions and methods for binding bio-affecting substances to surface membranes of bio-particles
BR9713978A (pt) 1996-10-28 2000-05-02 Nycomed Imaging As Agente diagnóstico alvejável e/ou terapeuticamente ativo, processo para preparação e uso do mesmo, formulação combinada, e, processos para gerar imagens intensificadas de um corpo animal humano ou não-humano e para investigação in vitro de alvejamento por um agente
ES2257771T3 (es) 1996-10-28 2006-08-01 Amersham Health As Agentes de contraste.
CA2278200A1 (en) * 1997-01-29 1998-07-30 Nycomed Imaging As Polymers
EP1037947B1 (de) 1997-07-28 2003-09-10 Amersham plc Cyaninfarbstoffe
US5942637A (en) * 1998-03-30 1999-08-24 North Dakota State University Research Foundation Compounds containing tetradecachlorocyclohexasilane dianion
WO1999058139A2 (en) * 1998-05-08 1999-11-18 The Regents Of The University Of California Methods for detecting and inhibiting angiogenesis
US6852318B1 (en) * 1998-05-08 2005-02-08 The Regents Of The University Of California Methods for detecting and inhibiting angiogenesis
JP2000095758A (ja) * 1998-09-18 2000-04-04 Schering Ag 近赤外蛍光造影剤および蛍光造影方法
US6230777B1 (en) 1999-02-04 2001-05-15 Midmac Systems, Inc. Filter forming and joining apparatus
NZ521735A (en) * 2000-04-12 2004-12-24 Amersham Health As Peptide-based compounds, their use as targeting vectors that bind to receptors associated with antiogenesis such as integrin receptors
NO20004795D0 (no) * 2000-09-26 2000-09-26 Nycomed Imaging As Peptidbaserte forbindelser
EP1337278A2 (de) 2000-11-27 2003-08-27 Bristol-Myers Squibb Medical Imaging, Inc. Gleichzeitiges imaging der kardialen perfusion und eines auf den vitronektin rezeptor zielgerichteten agens
RU2303042C2 (ru) * 2001-07-10 2007-07-20 Джи-И Хелткер АС Соединения на основе пептидов для направленной доставки к рецепторам интегринов
GB0116815D0 (en) 2001-07-10 2001-08-29 Nycomed Amersham Plc Improved chelator conjugates
GB0206750D0 (en) 2002-03-22 2002-05-01 Amersham Plc Radiofluorination methods
AU2003239030A1 (en) 2002-06-17 2003-12-31 Cartela R & D Ab Methods and uses of the integrin alpha 10 chain, for preventing progression of atherosclerosis plaque formation
US7063158B2 (en) 2003-06-16 2006-06-20 Deepwater Technologies, Inc. Bottom tensioned offshore oil well production riser
NO20033115D0 (no) 2003-07-08 2003-07-08 Amersham Health As Peptid-baserte forbindelser
GB0317815D0 (en) 2003-07-30 2003-09-03 Amersham Health As Imaging agents
WO2005019247A2 (en) * 2003-08-15 2005-03-03 Board Of Regents, The University Of Texas System Cyclic peptide and imaging compound compositions and uses for targeted imaging and therapy
US7431914B2 (en) * 2003-11-24 2008-10-07 Ge Healthcare As Contrast agent
US7763234B2 (en) * 2004-03-04 2010-07-27 Ge Healthcare As Pharmaceutical compounds
NZ551210A (en) 2004-06-16 2009-10-30 Ge Healthcare As Peptide-based compounds
ES2376557T3 (es) * 2004-06-16 2012-03-14 Ge Healthcare As Compuestos basados en péptidos.

Also Published As

Publication number Publication date
MX2007006050A (es) 2007-11-14
JP2012207027A (ja) 2012-10-25
CA2586621A1 (en) 2006-05-26
DE602005025911D1 (de) 2011-02-24
US8182790B2 (en) 2012-05-22
WO2006054904A3 (en) 2007-04-05
ES2358745T3 (es) 2011-05-13
WO2006054904A2 (en) 2006-05-26
EP1814598B1 (de) 2011-01-12
ZA200705043B (en) 2008-09-25
IL182898A0 (en) 2007-08-19
AU2005307195A1 (en) 2006-05-26
US20090208412A1 (en) 2009-08-20
EP2243496A3 (de) 2012-12-26
BRPI0518328A2 (pt) 2008-11-11
CN101107016A (zh) 2008-01-16
NO20073039L (no) 2007-08-16
EP2243496A2 (de) 2010-10-27
JP2008520658A (ja) 2008-06-19
EP1814598A2 (de) 2007-08-08
KR20070091609A (ko) 2007-09-11
CN101107016B (zh) 2011-11-16
JP5116480B2 (ja) 2013-01-09
RU2007118385A (ru) 2008-12-27

Similar Documents

Publication Publication Date Title
ATE494913T1 (de) Kontrastmittel für eine extrazelluläre matrix
DE60042522D1 (de) Cyanin- oder indocyaninefarbstoffe biokonjugate für biomedische anwendungen
ECSP066311A (es) Derivados de la piperazina y su uso como agentes terapéuticos
CY1110505T1 (el) Ανθρωπινα αντισωματα dr4 και χρησεις αυτων
ATE530168T1 (de) Magnetische nanoteilchen-zusammensetzungen und ihre verwendungen
CY1114679T1 (el) Συνθεσεις για διαγνωση και θεραπεια ασθενειων που συνδυαζονται με παρεκκλινουσα εκφραση φουτρινων (r-σπονδινων)
WO2003049684A3 (en) Pseudo-antibody constructs
CY1109151T1 (el) Αντισωματα dr4 και χρησεις αυτων
ATE445838T1 (de) Zusammensetzungen und verfahren zur modulation des transports durch die blut-hirn-schranke
ATE365054T1 (de) Diagnostisches abbildungsverfahren
ATE265863T1 (de) Neue zielgerichtete mittel zur diagnostischen und therapeutischen verwendung
IL173032A0 (en) Pyridazine derivatives and their use as therapeutic agents
ATE536413T1 (de) Auf knochen als ziel gerichtete alkalische phosphatase, kits und verwendungsverfahren dafür
BRPI0418552A (pt) compostos de alvejamento de piperidinila que seletivamente ligam-se à integrinas
ATE376428T1 (de) Metallkomplexverbindungen
ATE547009T1 (de) Zusammensetzungen und verfahren zur förderung von körperfettverlust
DE50207866D1 (de) Verwendung löslicher cytokeratin-1-fragmente in diagnostik
ATE425770T1 (de) Kontrastmittel
FR2870731B1 (fr) Composition pour la coloration des fibres keratiniques comprenant un pigment et des polymeres aptes a reagir l'un avec l'autre pour former des liaisons covalentes
DE60207612D1 (de) Verbindungen zur bilddarstellung der alzheimer-krankenheit
DE50101479D1 (de) Fluoresceinisothiocyanat-(fitc)-sinistrin, seine herstellung und verwendung
EP1611151A4 (de) Stq-peptide
EP1250091A4 (de) Hydrophile zyaninfarbstoffe
WO2005049095A3 (en) Contrast agent imaging angiotensin ii receptors
DE602008004556D1 (de) Zusammensetzungen und verfahren zum nachweis von störungen in verbindung mit histamin

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties