US20040009486A1
(en)
*
|
1999-10-29 |
2004-01-15 |
Sorge Joseph A. |
Compositions and methods utilizing DNA polymerases
|
US20050123940A1
(en)
*
|
1999-10-29 |
2005-06-09 |
Stratagene California |
Compositions and methods for synthesizing cDNA
|
US20030228616A1
(en)
*
|
1999-10-29 |
2003-12-11 |
Stratagene |
DNA polymerase mutants with reverse transcriptase activity
|
US8268605B2
(en)
|
1999-10-29 |
2012-09-18 |
Agilent Technologies, Inc. |
Compositions and methods utilizing DNA polymerases
|
DE60133992D1
(de)
*
|
2000-02-17 |
2008-06-26 |
Qiagen Gmbh |
Thermostabile chimäre nucleinsäurepolymerasen und ihre verwendungen
|
US6627424B1
(en)
|
2000-05-26 |
2003-09-30 |
Mj Bioworks, Inc. |
Nucleic acid modifying enzymes
|
DE10049211A1
(de)
*
|
2000-10-05 |
2002-04-18 |
Qiagen Gmbh |
Thermostabile Polymerase aus Thermococcus pacificus
|
US7211414B2
(en)
|
2000-12-01 |
2007-05-01 |
Visigen Biotechnologies, Inc. |
Enzymatic nucleic acid synthesis: compositions and methods for altering monomer incorporation fidelity
|
AU2002351193A1
(en)
*
|
2001-11-28 |
2003-06-10 |
Mj Bioworks Incorporated |
Parallel polymorphism scoring by amplification and error correction
|
EP1456394B2
(de)
|
2001-11-28 |
2011-04-27 |
Bio-Rad Laboratories, Inc. |
Verfahren zur verwendung verbesserter polymerasen
|
US20060234227A1
(en)
*
|
2002-05-14 |
2006-10-19 |
Alexei Slesarev |
Helix-hairpin-helix motifs to manipulate properties of dna processing enzymes
|
CA2518588A1
(en)
*
|
2002-07-25 |
2004-02-05 |
Mj Bioworks Incorporated |
Hybrid dna polymerase proteins having increased polymerase to exonuclease activity
|
US7560260B2
(en)
*
|
2002-07-25 |
2009-07-14 |
Bio-Rad Laboratories, Inc. |
Compositions with polymerase activity
|
US7666645B2
(en)
*
|
2002-10-23 |
2010-02-23 |
Bio-Rad Laboratories, Inc. |
Sso7-polymerase conjugate proteins
|
JP2006507012A
(ja)
*
|
2002-10-25 |
2006-03-02 |
ストラタジーン カリフォルニア |
減少した塩基類似体検出活性を有するdnaポリメラーゼ
|
US8283148B2
(en)
|
2002-10-25 |
2012-10-09 |
Agilent Technologies, Inc. |
DNA polymerase compositions for quantitative PCR and methods thereof
|
US7960157B2
(en)
|
2002-12-20 |
2011-06-14 |
Agilent Technologies, Inc. |
DNA polymerase blends and uses thereof
|
CA2519309A1
(en)
*
|
2003-03-25 |
2004-10-14 |
Stratagene California |
Dna polymerase fusions and uses thereof
|
US7417133B2
(en)
*
|
2004-02-27 |
2008-08-26 |
Institut Pasteur |
Methods for obtaining thermostable enzymes, DNA polymerase I variants from Thermus aquaticus having new catalytic activities, methods for obtaining the same, and applications of the same
|
DK2332977T3
(en)
*
|
2004-07-23 |
2016-02-29 |
Acceleron Pharma Inc |
ActRII receptor polypeptides
|
US20060105348A1
(en)
*
|
2004-11-15 |
2006-05-18 |
Lee Jun E |
Compositions and methods for the detection and discrimination of nucleic acids
|
WO2006074288A2
(en)
*
|
2005-01-06 |
2006-07-13 |
Applera Corporation |
Polypeptides having nucleic acid binding activity
|
EP2208796B1
(de)
*
|
2005-01-06 |
2014-06-18 |
Applied Biosystems, LLC |
Polypeptide mit Nukleinsäurebindungsaktivität und Zusammensetzungen und Verfahren zur Nukleinsäurenamplifikation
|
WO2007050125A2
(en)
*
|
2005-05-27 |
2007-05-03 |
William Marsh Rice University |
High processivity polymerases
|
US20070117114A1
(en)
*
|
2005-07-07 |
2007-05-24 |
Quanta Biosciences, Inc. |
Compositions and methods for increasing amplification efficiency
|
JP5241493B2
(ja)
*
|
2005-07-15 |
2013-07-17 |
アジレント・テクノロジーズ・インク |
Dna結合タンパク質−ポリメラーゼのキメラ
|
US20070059713A1
(en)
*
|
2005-09-09 |
2007-03-15 |
Lee Jun E |
SSB-DNA polymerase fusion proteins
|
CA3045808C
(en)
|
2005-11-23 |
2022-08-16 |
Acceleron Pharma, Inc. |
Activin-actriia antagonists and uses for promoting bone growth
|
US8128933B2
(en)
|
2005-11-23 |
2012-03-06 |
Acceleron Pharma, Inc. |
Method of promoting bone growth by an anti-activin B antibody
|
WO2007081841A2
(en)
|
2006-01-06 |
2007-07-19 |
Stratagene California |
Reaction buffer composition for nucleic acid replication with packed dna polymerases
|
EP2057289B1
(de)
|
2006-08-09 |
2016-08-10 |
Univ Singapore |
Verfahren für molekularbiologische anwendungen
|
US8895016B2
(en)
|
2006-12-18 |
2014-11-25 |
Acceleron Pharma, Inc. |
Antagonists of activin-actriia and uses for increasing red blood cell levels
|
ES2415666T3
(es)
|
2007-02-01 |
2013-07-26 |
Acceleron Pharma, Inc. |
Composiciones farmacéuticas que comprenden antagonistas de Activina-ActRIIa para uso en la prevención o el tratamiento de metástasis de cáncer de mama o pérdida ósea relacionada con el cáncer de mama
|
TW201907946A
(zh)
|
2007-02-02 |
2019-03-01 |
美商艾瑟勒朗法瑪公司 |
衍生自ActRIIB的變體與其用途
|
EP2484372A1
(de)
|
2007-02-09 |
2012-08-08 |
Acceleron Pharma, Inc. |
Activin-ActRIIa-Antagonisten und Anwendungen Davon zur Forderung des Knochenwachstums Bei Krebspatienten
|
CA2699936A1
(en)
|
2007-09-18 |
2009-03-26 |
Acceleron Pharma Inc. |
Activin-actriia antagonists and uses for decreasing or inhibiting fsh secretion
|
US8338094B2
(en)
|
2007-11-27 |
2012-12-25 |
Bio-Rad Laboratories, Inc. |
Reduced inhibition of one-step RT-PCR
|
WO2009087394A1
(en)
*
|
2008-01-11 |
2009-07-16 |
Genesys Ltd |
Cren7 chimeric protein
|
GB0803628D0
(en)
|
2008-02-28 |
2008-04-02 |
Genesys Ltd |
Enzyme
|
GB0804722D0
(en)
*
|
2008-03-14 |
2008-04-16 |
Genesys Ltd |
Enzyme
|
GB0804721D0
(en)
*
|
2008-03-14 |
2008-04-16 |
Genesys Ltd |
Enzyme
|
HRP20230761T1
(hr)
|
2008-08-14 |
2023-10-13 |
Acceleron Pharma Inc. |
Gdf zamke
|
US8216997B2
(en)
|
2008-08-14 |
2012-07-10 |
Acceleron Pharma, Inc. |
Methods for increasing red blood cell levels and treating anemia using a combination of GDF traps and erythropoietin receptor activators
|
JP5258512B2
(ja)
*
|
2008-10-30 |
2013-08-07 |
株式会社日立製作所 |
エキソヌクレアーゼ活性増強dnaポリメラーゼ変異体
|
JP5809059B2
(ja)
|
2008-11-03 |
2015-11-10 |
カパ バイオシステムズ, インコーポレイテッド |
改変a型dnaポリメラーゼ
|
WO2010062776A2
(en)
|
2008-11-03 |
2010-06-03 |
Kapabiosystems |
Chimeric dna polymerases
|
EP2382321A4
(de)
|
2009-01-08 |
2012-12-19 |
Bio Rad Laboratories |
Verfahren und zusammensetzungen zur verbesserung der wirksamkeit bei einer nukleinsäureverstärkungsreaktionen
|
EP3415621A1
(de)
|
2009-03-04 |
2018-12-19 |
Board Of Regents The University Of Texas System |
Stabilisierte reverse-transkriptase-fusionsproteine
|
US9778188B2
(en)
|
2009-03-11 |
2017-10-03 |
Industrial Technology Research Institute |
Apparatus and method for detection and discrimination molecular object
|
US8603792B2
(en)
|
2009-03-27 |
2013-12-10 |
Life Technologies Corporation |
Conjugates of biomolecules to nanoparticles
|
US8535925B2
(en)
|
2009-04-10 |
2013-09-17 |
Bio-Rad Laboratories, Inc. |
Modified DNase compositions and methods of use thereof
|
AU2010258931B2
(en)
|
2009-06-08 |
2015-04-23 |
Acceleron Pharma Inc. |
Methods for increasing thermogenic adipocytes
|
US8293881B2
(en)
|
2009-06-12 |
2012-10-23 |
Acceleron Pharma Inc. |
Isolated nucleic acid encoding a truncated ActRIIB fusion protein
|
US8889394B2
(en)
*
|
2009-09-07 |
2014-11-18 |
Empire Technology Development Llc |
Multiple domain proteins
|
CN102781518A
(zh)
*
|
2009-09-09 |
2012-11-14 |
阿塞勒隆制药公司 |
Actriib拮抗剂及其给药和用途
|
JP2013505016A
(ja)
*
|
2009-09-16 |
2013-02-14 |
マッシー ユニヴァーシティー |
融合ポリペプチドおよびその使用
|
ES2658292T3
(es)
|
2009-11-17 |
2018-03-09 |
Acceleron Pharma, Inc. |
Proteínas ActRIIB y variantes y usos de las mismas con respecto a la inducción de la utrofina para el tratamiento de la distrofia muscular
|
IN2012DN05145A
(de)
|
2009-11-19 |
2015-10-23 |
Solis Biodyne |
|
EP2539471B1
(de)
|
2010-02-26 |
2014-08-06 |
Life Technologies Corporation |
Verfahren zur sequenzierung bei verwendung einer modifizierte polymerase
|
US9482615B2
(en)
|
2010-03-15 |
2016-11-01 |
Industrial Technology Research Institute |
Single-molecule detection system and methods
|
US9670243B2
(en)
|
2010-06-02 |
2017-06-06 |
Industrial Technology Research Institute |
Compositions and methods for sequencing nucleic acids
|
US8865078B2
(en)
|
2010-06-11 |
2014-10-21 |
Industrial Technology Research Institute |
Apparatus for single-molecule detection
|
US20120070829A1
(en)
|
2010-09-10 |
2012-03-22 |
Bio-Rad Laboratories, Inc. |
Size selection of dna for chromatin analysis
|
US9617588B2
(en)
|
2010-10-05 |
2017-04-11 |
Thermo Fisher Scientific Baltics Uab |
Enzyme mixture
|
EP2638065A4
(de)
|
2010-11-08 |
2014-04-09 |
Acceleron Pharma Inc |
Actriia-bindende stoffe und ihre verwendungen
|
US9315787B2
(en)
|
2011-01-14 |
2016-04-19 |
Kapa Biosystems, Inc. |
Modified DNA polymerases for improved amplification
|
WO2012109315A1
(en)
|
2011-02-08 |
2012-08-16 |
Life Technologies Corporation |
Linking methods, compositions, systems, kits and apparatuses
|
EP2675913B1
(de)
|
2011-02-15 |
2016-12-14 |
Bio-Rad Laboratories, Inc. |
Erkennung von methylierung in einer subpopulation von genomischer dna
|
SG10201601853XA
(en)
|
2011-03-11 |
2016-04-28 |
Univ Singapore |
Pericyte progenitors from peripheral blood
|
EP2694670B1
(de)
|
2011-04-08 |
2017-07-19 |
Bio-Rad Laboratories, Inc. |
Pcr-reaktionsgemische mit verminderter nichtspezifischer aktivität
|
US8715987B2
(en)
|
2011-05-02 |
2014-05-06 |
New England Biolabs, Inc. |
Solubilized phospholipids for stabilizing nucleic acid polymerases
|
US8921044B2
(en)
|
2011-05-11 |
2014-12-30 |
New England Biolabs, Inc. |
DNA polymerase variants with reduced exonuclease activity and uses thereof
|
EP2707481B1
(de)
|
2011-05-11 |
2016-07-13 |
New England Biolabs, Inc. |
Dna-polymerasevarianten mit verminderter exonukleaseaktivität und ihre anwendung
|
US8470573B2
(en)
*
|
2011-06-21 |
2013-06-25 |
Bio-Rad Laboratories, Inc. |
Hybrid polymerases having the ability to produce long amplicons
|
EP2739752B1
(de)
|
2011-08-03 |
2017-07-19 |
Bio-Rad Laboratories, Inc. |
Filterung von kleinen nukleinsäuren anhand von permeabilisierten zellen
|
WO2014071158A1
(en)
|
2012-11-02 |
2014-05-08 |
Celgene Corporation |
Activin-actrii antagonists and uses for treating bone and other disorders
|
WO2015085230A1
(en)
|
2013-12-06 |
2015-06-11 |
Bio-Rad Laboratories, Inc. |
Fusion polymerases
|
CA2951926C
(en)
|
2014-06-13 |
2023-01-10 |
Acceleron Pharma, Inc. |
Methods and compositions for treating ulcers
|
EP3172332B1
(de)
|
2014-07-22 |
2020-10-14 |
Bio-rad Laboratories, Inc. |
Puffer zur verwendung mit polymerasen
|
US10072285B2
(en)
|
2014-08-19 |
2018-09-11 |
Bio-Rad Laboratories, Inc. |
RNA amplification methods
|
MA41052A
(fr)
|
2014-10-09 |
2017-08-15 |
Celgene Corp |
Traitement d'une maladie cardiovasculaire à l'aide de pièges de ligands d'actrii
|
EP3218471A1
(de)
|
2014-11-14 |
2017-09-20 |
Illumina, Inc. |
Polymerasen
|
EP3224359B1
(de)
|
2014-11-25 |
2023-10-25 |
Bio-Rad Laboratories, Inc. |
Arginin zur verbesserung der lagerstabilität von polymerase
|
ES2946160T3
(es)
|
2014-12-03 |
2023-07-13 |
Celgene Corp |
Antagonistas de activina-ActRII y usos para tratar síndrome mielodisplásico
|
ES2804843T3
(es)
|
2015-02-02 |
2021-02-09 |
Hoffmann La Roche |
Variantes de polimerasa
|
EP3486329A1
(de)
|
2015-02-17 |
2019-05-22 |
Bio-Rad Laboratories, Inc. |
Verfahren zur erzeugung und amplifizierung von cdns
|
WO2017050723A1
(en)
|
2015-09-22 |
2017-03-30 |
Genia Technologies, Inc. |
Pol7 polymerase variants
|
WO2017090685A1
(ja)
*
|
2015-11-27 |
2017-06-01 |
国立大学法人九州大学 |
Dnaポリメラーゼ変異体
|
LT3402880T
(lt)
|
2016-01-15 |
2024-03-12 |
Thermo Fisher Scientific Baltics Uab |
Termofiliniai dnr polimerazės mutantai
|
EP3402826A1
(de)
|
2016-01-15 |
2018-11-21 |
Thermo Fisher Scientific Baltics UAB |
Antikörper zur bindung von thermophilen dna-polymerasen
|
ES2880331T3
(es)
|
2016-02-29 |
2021-11-24 |
Genia Tech Inc |
Variantes de polimerasa
|
WO2017148861A1
(en)
|
2016-02-29 |
2017-09-08 |
Genia Technologies, Inc. |
Exonuclease deficient polymerases
|
CN108699540A
(zh)
|
2016-02-29 |
2018-10-23 |
吉尼亚科技公司 |
用于纳米孔测序的聚合酶-模板复合物
|
JP6720632B2
(ja)
*
|
2016-03-29 |
2020-07-08 |
東洋紡株式会社 |
融合タンパク質
|
WO2018054970A2
(en)
|
2016-09-22 |
2018-03-29 |
F. Hoffmann-La Roche Ag |
Pol6 polymerase variants
|
WO2019002178A1
(en)
|
2017-06-26 |
2019-01-03 |
Thermo Fisher Scientific Baltics Uab |
DNA MUTANTS THERMOPHILIC POLYMERASES
|
EP3728633A1
(de)
|
2017-12-22 |
2020-10-28 |
Thermo Fisher Scientific Baltics Uab |
Polymerasekettenreaktionszusammensetzung mit aminen
|
WO2020056044A1
(en)
*
|
2018-09-11 |
2020-03-19 |
Singular Genomics Systems, Inc. |
Modified archaeal family b polymerases
|
CN109266628B
(zh)
*
|
2018-10-09 |
2020-04-14 |
南京市胸科医院 |
一种融合的TaqDNA聚合酶及其应用
|
US10934533B1
(en)
|
2018-10-10 |
2021-03-02 |
New England Biolabs, Inc. |
Variant DNA polymerases having improved properties and method for improved isothermal amplification of a target DNA
|
CN109679932B
(zh)
*
|
2018-12-05 |
2020-03-17 |
广州奇辉生物科技有限公司 |
一种dna聚合酶、重组载体及它们的制备方法和应用
|
CN112175091A
(zh)
*
|
2019-07-05 |
2021-01-05 |
赛纳生物科技(北京)有限公司 |
通过功能结构域嫁接提高聚合酶大片段活性的方法及应用
|
US11512295B2
(en)
|
2019-09-12 |
2022-11-29 |
Singular Genomics Systems, Inc. |
Modified thermoccocus polymerases
|
WO2021163561A1
(en)
|
2020-02-13 |
2021-08-19 |
New England Biolabs, Inc. |
Variant family d dna polymerases
|
EP4103702A1
(de)
|
2020-02-13 |
2022-12-21 |
New England Biolabs, Inc. |
Varianten der d-dna-polymerasen
|
US11034942B1
(en)
|
2020-02-27 |
2021-06-15 |
Singular Genomics Systems, Inc. |
Modified pyrococcus polymerases and uses thereof
|
CN111518873A
(zh)
*
|
2020-05-11 |
2020-08-11 |
南京君华基因科技有限公司 |
一种优化的扩增目标核酸的方法及应用
|
PL241698B1
(pl)
*
|
2021-01-27 |
2022-11-21 |
Inst Biotechnologii I Medycyny Molekularnej |
Polimeraza Pwo-NeqSSB, sposób jej otrzymywania, plazmid rekombinantowy, startery oraz zastosowanie polimerazy
|
US11486001B2
(en)
|
2021-02-08 |
2022-11-01 |
Singular Genomics Systems, Inc. |
Methods and compositions for sequencing complementary polynucleotides
|
WO2022250676A1
(en)
|
2021-05-27 |
2022-12-01 |
New England Biolabs, Inc. |
Dnase i variants, compositions, methods, and kits
|
US11667968B2
(en)
|
2021-05-27 |
2023-06-06 |
New England Biolabs, Inc. |
Fragmentation of DNA
|
WO2022249133A1
(en)
|
2021-05-28 |
2022-12-01 |
Erebus Enzymes Inc. |
Ultra-processive, stutter-resistant polymerase system
|
WO2023089175A1
(en)
|
2021-11-22 |
2023-05-25 |
F. Hoffmann-La Roche Ag |
Thermostable polymerase variants
|
WO2023146243A1
(ko)
*
|
2022-01-26 |
2023-08-03 |
주식회사 씨젠 |
샘플 내 타겟 핵산을 검출하는 방법
|