DE60129008T2 - Methode zur identifizierung von regulatoren der bildung von protein-age-derivaten - Google Patents

Methode zur identifizierung von regulatoren der bildung von protein-age-derivaten Download PDF

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Publication number
DE60129008T2
DE60129008T2 DE60129008T DE60129008T DE60129008T2 DE 60129008 T2 DE60129008 T2 DE 60129008T2 DE 60129008 T DE60129008 T DE 60129008T DE 60129008 T DE60129008 T DE 60129008T DE 60129008 T2 DE60129008 T2 DE 60129008T2
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DE
Germany
Prior art keywords
glycosylation
protein
adp
ribose
histone
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60129008T
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German (de)
English (en)
Other versions
DE60129008D1 (de
Inventor
Elaine L. Tucson JACOBSON
Myron K. Tucson JACOBSON
Georg Thomas Tucson WONDRAK
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
NIADYNE CORP
Niadyne Corp Tucson
University of Kentucky
Original Assignee
NIADYNE CORP
Niadyne Corp Tucson
University of Kentucky
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
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Application filed by NIADYNE CORP, Niadyne Corp Tucson, University of Kentucky filed Critical NIADYNE CORP
Application granted granted Critical
Publication of DE60129008D1 publication Critical patent/DE60129008D1/de
Publication of DE60129008T2 publication Critical patent/DE60129008T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6875—Nucleoproteins
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2400/00—Assays, e.g. immunoassays or enzyme assays, involving carbohydrates

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  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Food Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DE60129008T 2000-04-14 2001-04-16 Methode zur identifizierung von regulatoren der bildung von protein-age-derivaten Expired - Lifetime DE60129008T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US19782900P 2000-04-14 2000-04-14
US197829P 2000-04-14
PCT/US2001/012368 WO2001079842A2 (fr) 2000-04-14 2001-04-16 Procede d'identification de regulateurs de la formation de produits finaux de glycation a avancement proteique (« age » proteique

Publications (2)

Publication Number Publication Date
DE60129008D1 DE60129008D1 (de) 2007-08-02
DE60129008T2 true DE60129008T2 (de) 2007-10-11

Family

ID=22730907

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60129008T Expired - Lifetime DE60129008T2 (de) 2000-04-14 2001-04-16 Methode zur identifizierung von regulatoren der bildung von protein-age-derivaten

Country Status (14)

Country Link
US (1) US6716635B2 (fr)
EP (1) EP1272843B1 (fr)
JP (1) JP3920641B2 (fr)
CN (1) CN1205480C (fr)
AT (1) ATE365319T1 (fr)
AU (2) AU5355501A (fr)
CY (1) CY1106852T1 (fr)
DE (1) DE60129008T2 (fr)
DK (1) DK1272843T3 (fr)
ES (1) ES2286117T3 (fr)
HK (1) HK1059117A1 (fr)
MX (1) MXPA02010194A (fr)
PT (1) PT1272843E (fr)
WO (1) WO2001079842A2 (fr)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8642284B1 (en) 1999-12-15 2014-02-04 Massachusetts Institute Of Technology Methods for identifying agents that alter NAD-dependent deacetylation activity of a SIR2 protein
US7452664B2 (en) 1999-12-15 2008-11-18 Massachusetts Institute Of Technology Methods for identifying agents which alter histone protein acetylation
AU5353901A (en) * 2000-04-14 2001-10-30 Niadyne Corp Methods of use of penicillamines for the treatment of conditions resulting from dna damage
US6751792B1 (en) * 2000-10-04 2004-06-15 Sun Microsystems, Inc. Using value-expression graphs for data-flow optimizations
US7572575B2 (en) 2000-12-13 2009-08-11 Massachusetts Institute Of Technology SIR2 activity
AU2003265505A1 (en) * 2002-08-16 2004-03-03 Imperial College Innovations Limited Compositions and methods for treating rage-associated disorders
JPWO2005040798A1 (ja) * 2003-10-29 2007-05-17 エーザイ・アール・アンド・ディー・マネジメント株式会社 アルツハイマー病の診断方法
FR2863620B1 (fr) * 2003-12-16 2007-05-25 Roquette Freres Utilisation d'au moins un cetose de 3 a 5 atomes de carbone comme substitut d'agents reticulants de proteines
ES2317214T3 (es) * 2004-03-02 2009-04-16 The Arizona Board Of Regents On Behalf Of The University Of Arizona Metodo para inducir la muerte celular con captadores de carbonilo.
SG161242A1 (en) * 2004-08-03 2010-05-27 Transtech Pharma Inc Rage fusion proteins and methods of use
EP1781700B1 (fr) 2004-08-03 2014-03-19 TransTech Pharma, LLC Protéines hybrides rage et leurs procédés d'utilisation
US20070099830A1 (en) 2005-04-21 2007-05-03 Massachusetts Institute Of Technology Sirt4 activities
CN101331384B (zh) * 2005-12-23 2011-11-09 G科德系统有限公司 定位图形
CN101410411A (zh) * 2006-02-09 2009-04-15 转化技术制药公司 Rage融合蛋白及使用方法
WO2007130302A2 (fr) 2006-05-05 2007-11-15 Transtech Pharma, Inc. Proteines de fusion rage, formulations et leurs procedes d'utilisation
US20080199467A1 (en) * 2007-02-15 2008-08-21 Mjalli Adnan M M Immunoglobulin fusion proteins and methods of making
CN101842382A (zh) 2007-06-14 2010-09-22 卡拉狄加制药公司 Rage融合蛋白
US9034341B2 (en) 2009-04-20 2015-05-19 Transtech Pharma, Llc Control of RAGE fusion protein glycosylation and RAGE fusion protein compositions
US9309304B2 (en) * 2012-05-16 2016-04-12 Cornell University Glycation cross-link breakers to increase resistance to enzymatic degradation
CN108776131B (zh) * 2018-03-19 2020-06-09 深圳市南山区疾病预防控制中心 一种食品中AGEs含量的检测方法
CN109970730B (zh) * 2019-04-30 2022-06-17 华东理工大学 一种双功能荧光探针及其制备方法和应用
JP7411205B2 (ja) 2019-09-30 2024-01-11 丸善製薬株式会社 ＡＧＥｓ形成抑制剤及びその製造方法
CN111007135B (zh) * 2019-12-25 2022-08-02 广东食品药品职业学院 一种植物提取物抗糖化效果的评估方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2711990B1 (fr) * 1993-11-05 1995-12-08 Exsymol Sa Produit pseudodipeptide possédant un groupement imidazole, et applications thérapeutiques, cosmétologiques et agroalimentaires.
FR2776188B1 (fr) * 1998-03-20 2000-06-16 Fabre Pierre Dermo Cosmetique Oleamide de glycylglycine en dermo-cosmetologie

Also Published As

Publication number Publication date
CY1106852T1 (el) 2012-05-23
WO2001079842A3 (fr) 2002-10-24
PT1272843E (pt) 2007-10-01
JP3920641B2 (ja) 2007-05-30
WO2001079842A2 (fr) 2001-10-25
US20020037496A1 (en) 2002-03-28
AU5355501A (en) 2001-10-30
HK1059117A1 (en) 2004-06-18
ATE365319T1 (de) 2007-07-15
JP2003531376A (ja) 2003-10-21
CN1205480C (zh) 2005-06-08
DK1272843T3 (da) 2007-10-08
ES2286117T3 (es) 2007-12-01
CN1451096A (zh) 2003-10-22
EP1272843A2 (fr) 2003-01-08
AU2001253555B2 (en) 2005-01-06
DE60129008D1 (de) 2007-08-02
EP1272843B1 (fr) 2007-06-20
MXPA02010194A (es) 2004-08-19
US6716635B2 (en) 2004-04-06

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