DE60129008D1 - Methode zur identifizierung von regulatoren der bildung von protein-age-derivaten - Google Patents

Methode zur identifizierung von regulatoren der bildung von protein-age-derivaten

Info

Publication number
DE60129008D1
DE60129008D1 DE60129008T DE60129008T DE60129008D1 DE 60129008 D1 DE60129008 D1 DE 60129008D1 DE 60129008 T DE60129008 T DE 60129008T DE 60129008 T DE60129008 T DE 60129008T DE 60129008 D1 DE60129008 D1 DE 60129008D1
Authority
DE
Germany
Prior art keywords
formation
protein
inhibit
identifying
compounds
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60129008T
Other languages
English (en)
Other versions
DE60129008T2 (de
Inventor
Elaine L Jacobson
Myron K Jacobson
Georg Thomas Wondrak
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
NIADYNE CORP
University of Kentucky
Original Assignee
NIADYNE CORP
University of Kentucky
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22730907&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE60129008(D1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by NIADYNE CORP, University of Kentucky filed Critical NIADYNE CORP
Application granted granted Critical
Publication of DE60129008D1 publication Critical patent/DE60129008D1/de
Publication of DE60129008T2 publication Critical patent/DE60129008T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6875Nucleoproteins
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2400/00Assays, e.g. immunoassays or enzyme assays, involving carbohydrates

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Food Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DE60129008T 2000-04-14 2001-04-16 Methode zur identifizierung von regulatoren der bildung von protein-age-derivaten Expired - Lifetime DE60129008T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US19782900P 2000-04-14 2000-04-14
US197829P 2000-04-14
PCT/US2001/012368 WO2001079842A2 (en) 2000-04-14 2001-04-16 Method for identifying regulators of protein-age formation

Publications (2)

Publication Number Publication Date
DE60129008D1 true DE60129008D1 (de) 2007-08-02
DE60129008T2 DE60129008T2 (de) 2007-10-11

Family

ID=22730907

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60129008T Expired - Lifetime DE60129008T2 (de) 2000-04-14 2001-04-16 Methode zur identifizierung von regulatoren der bildung von protein-age-derivaten

Country Status (14)

Country Link
US (1) US6716635B2 (de)
EP (1) EP1272843B1 (de)
JP (1) JP3920641B2 (de)
CN (1) CN1205480C (de)
AT (1) ATE365319T1 (de)
AU (2) AU2001253555B2 (de)
CY (1) CY1106852T1 (de)
DE (1) DE60129008T2 (de)
DK (1) DK1272843T3 (de)
ES (1) ES2286117T3 (de)
HK (1) HK1059117A1 (de)
MX (1) MXPA02010194A (de)
PT (1) PT1272843E (de)
WO (1) WO2001079842A2 (de)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7452664B2 (en) 1999-12-15 2008-11-18 Massachusetts Institute Of Technology Methods for identifying agents which alter histone protein acetylation
US8642284B1 (en) 1999-12-15 2014-02-04 Massachusetts Institute Of Technology Methods for identifying agents that alter NAD-dependent deacetylation activity of a SIR2 protein
WO2001078718A1 (en) * 2000-04-14 2001-10-25 Niadyne Corporation Methods of use of penicillamines for the treatment of conditions resulting from dna damage
US6751792B1 (en) * 2000-10-04 2004-06-15 Sun Microsystems, Inc. Using value-expression graphs for data-flow optimizations
US7572575B2 (en) 2000-12-13 2009-08-11 Massachusetts Institute Of Technology SIR2 activity
CN1774445A (zh) * 2002-08-16 2006-05-17 惠氏公司 用于治疗rage相关病症的组合物和方法
JPWO2005040798A1 (ja) * 2003-10-29 2007-05-17 エーザイ・アール・アンド・ディー・マネジメント株式会社 アルツハイマー病の診断方法
FR2863620B1 (fr) * 2003-12-16 2007-05-25 Roquette Freres Utilisation d'au moins un cetose de 3 a 5 atomes de carbone comme substitut d'agents reticulants de proteines
EP1720538B1 (de) * 2004-03-02 2008-11-12 The Arizona Board of Regents on Behalf of the University of Arizona Verfahren zur einleitung von zelltod mit carbonyl-fängern
NZ552842A (en) * 2004-08-03 2010-05-28 Univ Columbia Rage fusion proteins and methods of use
AP2007003869A0 (en) * 2004-08-03 2007-02-28 Transtech Pharma Inc Rage fusion proteins and methods of use
US20070099830A1 (en) 2005-04-21 2007-05-03 Massachusetts Institute Of Technology Sirt4 activities
RU2431804C2 (ru) * 2005-12-23 2011-10-20 ДжиКоудер Системз АБ Шаблон позиционирования
NZ569545A (en) * 2006-02-09 2011-11-25 Transtech Pharma Inc Rage fusion proteins and methods of use for treating inflammation
MX2008013863A (es) 2006-05-05 2008-11-14 Transtech Pharma Inc Proteinas de fusion de rage y sus metodos de uso.
US20080199467A1 (en) * 2007-02-15 2008-08-21 Mjalli Adnan M M Immunoglobulin fusion proteins and methods of making
AU2008265983B2 (en) 2007-06-14 2013-06-20 Galactica Pharmaceuticals, Inc. RAGE fusion proteins
CN102803292A (zh) 2009-04-20 2012-11-28 辉瑞公司 蛋白质糖基化的控制及其相关组合物和方法
US9309304B2 (en) * 2012-05-16 2016-04-12 Cornell University Glycation cross-link breakers to increase resistance to enzymatic degradation
CN108776131B (zh) * 2018-03-19 2020-06-09 深圳市南山区疾病预防控制中心 一种食品中AGEs含量的检测方法
CN109970730B (zh) * 2019-04-30 2022-06-17 华东理工大学 一种双功能荧光探针及其制备方法和应用
JP7411205B2 (ja) * 2019-09-30 2024-01-11 丸善製薬株式会社 AGEs形成抑制剤及びその製造方法
CN111007135B (zh) * 2019-12-25 2022-08-02 广东食品药品职业学院 一种植物提取物抗糖化效果的评估方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2711990B1 (fr) 1993-11-05 1995-12-08 Exsymol Sa Produit pseudodipeptide possédant un groupement imidazole, et applications thérapeutiques, cosmétologiques et agroalimentaires.
FR2776188B1 (fr) 1998-03-20 2000-06-16 Fabre Pierre Dermo Cosmetique Oleamide de glycylglycine en dermo-cosmetologie

Also Published As

Publication number Publication date
MXPA02010194A (es) 2004-08-19
JP3920641B2 (ja) 2007-05-30
HK1059117A1 (en) 2004-06-18
US6716635B2 (en) 2004-04-06
AU2001253555B2 (en) 2005-01-06
ES2286117T3 (es) 2007-12-01
DK1272843T3 (da) 2007-10-08
EP1272843A2 (de) 2003-01-08
DE60129008T2 (de) 2007-10-11
WO2001079842A2 (en) 2001-10-25
ATE365319T1 (de) 2007-07-15
JP2003531376A (ja) 2003-10-21
PT1272843E (pt) 2007-10-01
CN1205480C (zh) 2005-06-08
WO2001079842A3 (en) 2002-10-24
CY1106852T1 (el) 2012-05-23
EP1272843B1 (de) 2007-06-20
US20020037496A1 (en) 2002-03-28
AU5355501A (en) 2001-10-30
CN1451096A (zh) 2003-10-22

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