MXPA02010194A - Metodo para identificar reguladores de formacion de proteina-producto final de glicacion avanzada (proteina-age). - Google Patents

Metodo para identificar reguladores de formacion de proteina-producto final de glicacion avanzada (proteina-age).

Info

Publication number
MXPA02010194A
MXPA02010194A MXPA02010194A MXPA02010194A MXPA02010194A MX PA02010194 A MXPA02010194 A MX PA02010194A MX PA02010194 A MXPA02010194 A MX PA02010194A MX PA02010194 A MXPA02010194 A MX PA02010194A MX PA02010194 A MXPA02010194 A MX PA02010194A
Authority
MX
Mexico
Prior art keywords
protein
formation
end product
age
advanced glycation
Prior art date
Application number
MXPA02010194A
Other languages
English (en)
Inventor
Georg Thomas Wondrak
Original Assignee
Niadyne Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22730907&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MXPA02010194(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Niadyne Corp filed Critical Niadyne Corp
Publication of MXPA02010194A publication Critical patent/MXPA02010194A/es

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6875—Nucleoproteins
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2400/00—Assays, e.g. immunoassays or enzyme assays, involving carbohydrates

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Food Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

La invencion se refiere a metodos para identificar compuestos que afectan la tension celular; en particular, el metodo se refiere a identificar compuestos que inhiben la formacion de proteina-producto final de glicacion avanzada, en que los compuestos son barredores de carbonilo que inhiben la formacion; el ensayo implica combinar la sustancia de interes con histona H1 y ADP-ribosa, y medir luego la fluorescencia y el entrelazamiento de proteina; se han identificado varios inhibidores de la glicacion de proteina-AGE, usando este ensayo.
MXPA02010194A 2000-04-14 2001-04-16 Metodo para identificar reguladores de formacion de proteina-producto final de glicacion avanzada (proteina-age). MXPA02010194A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US19782900P 2000-04-14 2000-04-14
PCT/US2001/012368 WO2001079842A2 (en) 2000-04-14 2001-04-16 Method for identifying regulators of protein-age formation

Publications (1)

Publication Number Publication Date
MXPA02010194A true MXPA02010194A (es) 2004-08-19

Family

ID=22730907

Family Applications (1)

Application Number Title Priority Date Filing Date
MXPA02010194A MXPA02010194A (es) 2000-04-14 2001-04-16 Metodo para identificar reguladores de formacion de proteina-producto final de glicacion avanzada (proteina-age).

Country Status (14)

Country Link
US (1) US6716635B2 (es)
EP (1) EP1272843B1 (es)
JP (1) JP3920641B2 (es)
CN (1) CN1205480C (es)
AT (1) ATE365319T1 (es)
AU (2) AU2001253555B2 (es)
CY (1) CY1106852T1 (es)
DE (1) DE60129008T2 (es)
DK (1) DK1272843T3 (es)
ES (1) ES2286117T3 (es)
HK (1) HK1059117A1 (es)
MX (1) MXPA02010194A (es)
PT (1) PT1272843E (es)
WO (1) WO2001079842A2 (es)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8642284B1 (en) 1999-12-15 2014-02-04 Massachusetts Institute Of Technology Methods for identifying agents that alter NAD-dependent deacetylation activity of a SIR2 protein
US7452664B2 (en) 1999-12-15 2008-11-18 Massachusetts Institute Of Technology Methods for identifying agents which alter histone protein acetylation
EP1274418A4 (en) * 2000-04-14 2005-02-09 Niadyne Corp USE OF PENICILLAMINES FOR THE TREATMENT OF STATES RESULTING FROM DNA DEGRADATION
US6751792B1 (en) * 2000-10-04 2004-06-15 Sun Microsystems, Inc. Using value-expression graphs for data-flow optimizations
US7572575B2 (en) 2000-12-13 2009-08-11 Massachusetts Institute Of Technology SIR2 activity
AU2003265505A1 (en) * 2002-08-16 2004-03-03 Imperial College Innovations Limited Compositions and methods for treating rage-associated disorders
EP1693671A4 (en) * 2003-10-29 2008-03-19 Eisai R&D Man Co Ltd METHOD FOR DIAGNOSING ALZHEIMER'S DISEASE
FR2863620B1 (fr) * 2003-12-16 2007-05-25 Roquette Freres Utilisation d'au moins un cetose de 3 a 5 atomes de carbone comme substitut d'agents reticulants de proteines
RS50632B (sr) * 2004-03-02 2010-06-30 The Arizona Boardof Regents On Behalf Of The University Of Arizona Postupak za indukciju ćelijske smrti sa karbonil-sakupljačima
AU2005271449A1 (en) * 2004-08-03 2006-02-16 The Trustees Of Columbia University In The City Of New York RAGE fusion proteins and methods of use
BRPI0514052A (pt) * 2004-08-03 2008-05-27 Transtech Pharma Inc proteìnas de fusão rage e métodos de utilização
US20070099830A1 (en) 2005-04-21 2007-05-03 Massachusetts Institute Of Technology Sirt4 activities
WO2007073272A1 (en) * 2005-12-23 2007-06-28 Gcoder Systems Ab Positioning pattern
EA015657B1 (ru) * 2006-02-09 2011-10-31 Транстек Фарма, Инк. Слитые белки rage и способы применения
NZ571692A (en) * 2006-05-05 2012-01-12 Transtech Pharma Inc Rage fusion proteins, formulations, and methods of use thereof
US20080199467A1 (en) * 2007-02-15 2008-08-21 Mjalli Adnan M M Immunoglobulin fusion proteins and methods of making
BRPI0813452A2 (pt) 2007-06-14 2017-05-23 Galactica Pharmaceuticals Inc protéinas de fusão rage.
AU2010240569A1 (en) 2009-04-20 2011-10-20 Pfizer Inc. Control of protein glycosylation and compositions and methods relating thereto
US9309304B2 (en) * 2012-05-16 2016-04-12 Cornell University Glycation cross-link breakers to increase resistance to enzymatic degradation
CN108776131B (zh) * 2018-03-19 2020-06-09 深圳市南山区疾病预防控制中心 一种食品中AGEs含量的检测方法
CN109970730B (zh) * 2019-04-30 2022-06-17 华东理工大学 一种双功能荧光探针及其制备方法和应用
JP7411205B2 (ja) 2019-09-30 2024-01-11 丸善製薬株式会社 ＡＧＥｓ形成抑制剤及びその製造方法
CN111007135B (zh) * 2019-12-25 2022-08-02 广东食品药品职业学院 一种植物提取物抗糖化效果的评估方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2711990B1 (fr) 1993-11-05 1995-12-08 Exsymol Sa Produit pseudodipeptide possédant un groupement imidazole, et applications thérapeutiques, cosmétologiques et agroalimentaires.
FR2776188B1 (fr) 1998-03-20 2000-06-16 Fabre Pierre Dermo Cosmetique Oleamide de glycylglycine en dermo-cosmetologie

Also Published As

Publication number Publication date
WO2001079842A2 (en) 2001-10-25
CN1205480C (zh) 2005-06-08
JP3920641B2 (ja) 2007-05-30
PT1272843E (pt) 2007-10-01
AU5355501A (en) 2001-10-30
DE60129008D1 (de) 2007-08-02
US20020037496A1 (en) 2002-03-28
CY1106852T1 (el) 2012-05-23
ES2286117T3 (es) 2007-12-01
ATE365319T1 (de) 2007-07-15
HK1059117A1 (en) 2004-06-18
EP1272843B1 (en) 2007-06-20
DK1272843T3 (da) 2007-10-08
DE60129008T2 (de) 2007-10-11
US6716635B2 (en) 2004-04-06
CN1451096A (zh) 2003-10-22
AU2001253555B2 (en) 2005-01-06
EP1272843A2 (en) 2003-01-08
JP2003531376A (ja) 2003-10-21
WO2001079842A3 (en) 2002-10-24

Similar Documents

Publication Publication Date Title
MXPA02010194A (es) Metodo para identificar reguladores de formacion de proteina-producto final de glicacion avanzada (proteina-age).
WO2003062462A3 (en) Method for isolating nucleic acids and protein from a single sample
Van Maanen et al. Formation of nitrosamines during consumption of nitrate-and amine-rich foods, and the influence of the use of mouthwashes.
BRPI0108364B8 (pt) “receptáculo para receber amostras, e, método para isolar ácido nucleico de sangue total
WO2005005462A3 (en) Blys antagonists and uses thereof
EP1994142A4 (en) METHODS AND COMPOSITIONS FOR RAPID ISOLATION OF SMALL RNA MOLECULES
DE60028732D1 (de) Verfahren zur erhaltung der dns-integrität
BR0211213A (pt) matrizes, disposições ordenadas de elementos, sistemas e métodos para análise de biomoléculas
WO2003016482A3 (en) Methyltransferase genes and uses thereof
DK1399590T3 (da) Happier kortlægning
WO2004033718A3 (en) Trap-tagging: a novel method for the identification and purification of rna-protein complexes
ATE515697T1 (de) Massenspektrometrisches analyseverfahren
WO2004101788A3 (en) Small interfering rna libraries and methods of synthesis and use
IL165390A0 (en) Methods for identifying and extracting endotoxin
ATE474922T1 (de) Fluoreszenzproteine aus copepoda-spezies und verfahren zur verwendung davon
ATE509946T1 (de) Fluoreszenzproteine und chromoproteine aus nicht- aequorea-hydrozoa-spezies sowie verfahren zur verwendung davon
GB0509611D0 (en) Method and device for imaging a sample
WO2008109533A3 (en) Human antibodies that bind multiple irta family proteins, and uses thereof
DK1051491T3 (da) Equin Fc Epsilon receptor-alfa-kæde-nukleinsyremolekyler, korresponderende proteiner og anvendelse heraf
DE602004011228D1 (de) Verfahren und zusammensetzungen zur bestimmung glycierter proteine
WO2005003151A3 (en) Method and apparatus for continuous large-scale radiolabeling of proteins
AR019862A1 (es) Una proteina-1 de union a angiostatina (abp-1) de mamifero aislada, una molecula de acido nucleico aislada que la codifica, un vector que la comprende, una celula recombinante, un anticuerpo o fragmento de anticuerpo, un metodo de rastreo, uso de las proteinas.
WO2000047714A3 (en) Isolation and characterization of heat shock protein
WO2001004354A3 (en) Use of ras inhibitors of inhibiting muscle atrophy
Sacharidou et al. RNA editing complex interactions with a site for full-round U deletion in Trypanosoma brucei

Legal Events

Date Code Title Description
FG Grant or registration