DE60111628D1 - Metallchelatisierende gemische - Google Patents
Metallchelatisierende gemischeInfo
- Publication number
- DE60111628D1 DE60111628D1 DE60111628T DE60111628T DE60111628D1 DE 60111628 D1 DE60111628 D1 DE 60111628D1 DE 60111628 T DE60111628 T DE 60111628T DE 60111628 T DE60111628 T DE 60111628T DE 60111628 D1 DE60111628 D1 DE 60111628D1
- Authority
- DE
- Germany
- Prior art keywords
- metal
- chelatizing
- mixtures
- cooh
- integer
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/5306—Improving reaction conditions, e.g. reduction of non-specific binding, promotion of specific binding
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J45/00—Ion-exchange in which a complex or a chelate is formed; Use of material as complex or chelate forming ion-exchangers; Treatment of material for improving the complex or chelate forming ion-exchange properties
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
- C07C323/50—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton
- C07C323/51—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
- C07C323/57—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being further substituted by nitrogen atoms, not being part of nitro or nitroso groups
- C07C323/58—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being further substituted by nitrogen atoms, not being part of nitro or nitroso groups with amino groups bound to the carbon skeleton
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/11—Compounds covalently bound to a solid support
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/25—Chemistry: analytical and immunological testing including sample preparation
- Y10T436/25125—Digestion or removing interfering materials
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Organic Chemistry (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Physics & Mathematics (AREA)
- Pathology (AREA)
- General Health & Medical Sciences (AREA)
- Cell Biology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Physics & Mathematics (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- Bioinformatics & Computational Biology (AREA)
- Biophysics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Peptides Or Proteins (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Detergent Compositions (AREA)
- Solid-Sorbent Or Filter-Aiding Compositions (AREA)
- Treatment Of Liquids With Adsorbents In General (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US558001 | 2000-04-24 | ||
US09/558,001 US6623655B1 (en) | 2000-04-24 | 2000-04-24 | Metal chelating compositions |
PCT/US2001/011529 WO2001081365A2 (en) | 2000-04-24 | 2001-04-10 | Metal chelating compositions |
Publications (3)
Publication Number | Publication Date |
---|---|
DE60111628D1 true DE60111628D1 (de) | 2005-07-28 |
DE60111628T2 DE60111628T2 (de) | 2006-05-11 |
DE60111628T3 DE60111628T3 (de) | 2009-04-02 |
Family
ID=24227740
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE60111628T Expired - Lifetime DE60111628T3 (de) | 2000-04-24 | 2001-04-10 | Metallchelatisierende gemische |
Country Status (8)
Country | Link |
---|---|
US (3) | US6623655B1 (de) |
EP (2) | EP1627683A3 (de) |
JP (1) | JP4298201B2 (de) |
AT (1) | ATE298321T1 (de) |
AU (1) | AU2001251479A1 (de) |
DE (1) | DE60111628T3 (de) |
ES (1) | ES2244609T5 (de) |
WO (1) | WO2001081365A2 (de) |
Families Citing this family (40)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6623655B1 (en) * | 2000-04-24 | 2003-09-23 | Sigma-Aldrich Co. | Metal chelating compositions |
CA2488819A1 (en) * | 2002-03-28 | 2003-11-06 | Rutgers, The State University Of New Jersey | Bis-transition-metal-chelate-probes |
US6919333B2 (en) * | 2002-11-12 | 2005-07-19 | Rutgers, The State University Of New Jersey | Bis-transition-metal-chelate probes |
WO2003087047A1 (en) * | 2002-04-11 | 2003-10-23 | Peptron Co., Ltd. | Metal chelate composition, macromolecule complex thereof, preparing method thereof and use |
WO2004025259A2 (en) * | 2002-09-12 | 2004-03-25 | Molecular Probes, Inc. | Site-specific labeling of affinity tags in fusion proteins |
US20060141554A1 (en) * | 2002-09-12 | 2006-06-29 | Gee Kyle R | Site-specific labeling of affinity tags in fusion proteins |
CN100500837C (zh) * | 2002-10-18 | 2009-06-17 | 普罗梅加公司 | 分离分子的方法 |
US7371852B2 (en) * | 2003-01-22 | 2008-05-13 | Serenex, Inc. | Alkyl-linked nucleotide compositions |
US7319014B2 (en) | 2003-02-24 | 2008-01-15 | New England Biolabs, Inc. | Overexpression, purification and characterization of a thermolabile phosphatase |
SE526214C2 (sv) * | 2003-02-28 | 2005-07-26 | Amersham Biosciences Ab | Ett sätt att generera metallkelaterande affinitetsligander |
SE0301011D0 (sv) * | 2003-04-04 | 2003-04-04 | Amersham Biosciences Ab | Preparation of a metal chelating separation medium |
WO2004099384A2 (en) * | 2003-05-02 | 2004-11-18 | Sigma-Aldrich Co. | Solid phase cell lysis and capture platform |
GB0406015D0 (en) * | 2004-03-17 | 2004-04-21 | Dynal Biotech Asa | Improvements in magnetic polymer particles |
JP4456954B2 (ja) * | 2004-07-16 | 2010-04-28 | 富士ゼロックス株式会社 | 電子写真感光体、プロセスカートリッジおよび電子写真装置 |
JP4456953B2 (ja) * | 2004-07-16 | 2010-04-28 | 富士ゼロックス株式会社 | 画像形成装置及びプロセスカートリッジ |
JP4456951B2 (ja) * | 2004-07-16 | 2010-04-28 | 富士ゼロックス株式会社 | 画像形成装置及びプロセスカートリッジ |
JP4456952B2 (ja) | 2004-07-16 | 2010-04-28 | 富士ゼロックス株式会社 | 電子写真感光体、プロセスカートリッジおよび電子写真装置 |
US7153574B2 (en) * | 2004-07-16 | 2006-12-26 | Xerox Corporation | Surface grafted metal oxide particles and compositions comprising the same |
WO2006026248A1 (en) | 2004-08-25 | 2006-03-09 | Sigma-Aldrich Co. | Compositions and methods employing zwitterionic detergent combinations |
EP1848529A1 (de) * | 2005-02-14 | 2007-10-31 | GE Healthcare Bio-Sciences AB | Flüssigkeitschromatographieverfahren |
US7741053B2 (en) | 2005-05-13 | 2010-06-22 | Sigma-Aldrich Co. | Processes for purification of recombinant proteins |
JP4918764B2 (ja) * | 2005-09-05 | 2012-04-18 | 東ソー株式会社 | 生分解性アミノポリカルボン酸誘導体 |
JP4918763B2 (ja) * | 2005-09-05 | 2012-04-18 | 東ソー株式会社 | ポリカルボン酸アミド誘導体およびキレート剤 |
GB0610479D0 (en) * | 2006-05-26 | 2006-07-05 | Ge Healthcare Bio Sciences Ab | A method for generating metal chelating affinity ligands |
CN101101283A (zh) * | 2006-07-05 | 2008-01-09 | 中国科学院大连化学物理研究所 | 一种分离富集磷酸化肽的方法 |
US20080158558A1 (en) * | 2006-12-28 | 2008-07-03 | Handong Li | Phosphopeptide detection and surface enhanced Raman spectroscopy |
JP5629208B2 (ja) | 2007-08-06 | 2014-11-19 | マックス−プランク−ゲゼルシャフト ツール フォーデルング デル ヴィッセンシャフテン エー.ヴェー. | 固定金属イオンクロマトグラフィー(imac)のためのキレート基の固定 |
EP2022561A1 (de) * | 2007-08-06 | 2009-02-11 | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. | Immobilisierung von chelatbildenden Gruppen für immobilisierte Metallionenchromatographie (IMAC) |
ES2552337T3 (es) | 2009-03-03 | 2015-11-27 | Grifols Therapeutics Inc. | Procedimientos para la preparación de plasminógeno |
WO2012097344A2 (en) * | 2011-01-13 | 2012-07-19 | University Of Kansas | Metal abstraction peptide and uses thereof |
JP5889590B2 (ja) * | 2011-10-05 | 2016-03-22 | 東ソー株式会社 | タンパク質の分析、分離・精製用吸着剤 |
HU230585B1 (hu) | 2012-05-30 | 2017-01-30 | Budapesti Műszaki és Gazdaságtudományi Egyetem | Fehérjék megkötésére és elválasztására alkalmas lantanida fémionokkal komplexált hordozók |
US9187735B2 (en) | 2012-06-01 | 2015-11-17 | University Of Kansas | Metal abstraction peptide with superoxide dismutase activity |
EP2922944B1 (de) | 2012-12-19 | 2019-01-09 | Rohm and Haas Company | Spülmaschinenspülmittel |
JP6466763B2 (ja) * | 2015-04-06 | 2019-02-06 | 川研ファインケミカル株式会社 | 水溶性シスチン誘導体またはその塩およびそれを含有する化粧料組成物 |
CN106000326B (zh) * | 2016-06-14 | 2018-11-02 | 常州天地人和生物科技有限公司 | 一种超耐受金属螯合亲和填料的制备和应用 |
CN107192707B (zh) * | 2017-05-11 | 2020-02-07 | 金花企业(集团)股份有限公司西安金花制药厂 | 同时测定人工虎骨粉中砷、镉、铜、汞、铅五种重金属元素的方法 |
CN109020853A (zh) * | 2018-08-29 | 2018-12-18 | 武汉汇研生物科技股份有限公司 | 一种金属螯合配基及其制备方法 |
DK3887033T3 (da) | 2018-11-28 | 2024-08-12 | Cube Biotech Gmbh | Chelatdannende materiale i fast fase, metode til fremstilling heraf og anvendelse heraf til oprensning af proteiner |
WO2024026446A1 (en) | 2022-07-29 | 2024-02-01 | Genentech, Inc. | Method for purifying a polypeptide comprising two imac steps and apparatus therefore |
Family Cites Families (32)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2205995A (en) | 1937-01-20 | 1940-06-25 | Ig Farbenindustrie Ag | Production of amino carboxylic acid nitriles |
US2885428A (en) | 1958-01-08 | 1959-05-05 | Rohm & Haas | 2-isothiocyanatoisocamphane |
IT754322A (de) | 1965-01-25 | |||
US3959342A (en) | 1970-08-24 | 1976-05-25 | Bethlehem Steel Corporation | Process for the preparation of nitrilotriacetonitrile (NTN) |
JPS512708A (ja) * | 1974-06-28 | 1976-01-10 | Lion Fat Oil Co Ltd | Senjozaisoseibutsu |
JPS55139347A (en) | 1979-04-12 | 1980-10-31 | Nippon Paint Co Ltd | Amino compound |
SE449225B (sv) † | 1980-12-18 | 1987-04-13 | Gelinnovation Hb | Gelprodukt baserad pa partiklar innehallande galaktan for separationsendamal, molekyl- och partikelimmobilisering |
SE451802B (sv) * | 1984-05-10 | 1987-11-02 | Jerker Porath | Produkt for adsorption av metalljoner |
SE470099B (sv) † | 1984-05-17 | 1993-11-08 | Jerker Porath | Sulfonaktiverade tioeteradsorbenter för separation av t ex protein |
SE454885B (sv) | 1984-10-19 | 1988-06-06 | Exploaterings Ab Tbf | Polymerbelagda partiklar med immobiliserade metalljoner pa sin yta jemte forfarande for framstellning derav |
SE452557B (sv) † | 1984-10-30 | 1987-12-07 | Exploaterings Ab Tbf | Amfipatisk gelprodukt for kromatografisk och satsvis adsorption |
US4569794A (en) | 1984-12-05 | 1986-02-11 | Eli Lilly And Company | Process for purifying proteins and compounds useful in such process |
US4664806A (en) * | 1985-01-22 | 1987-05-12 | Ciba-Geigy Corporation | Anionically modified polysaccharides chromatography agents |
CA1329215C (en) | 1986-07-10 | 1994-05-03 | Heinz Dobeli | Process for the manufacture of nitrilotriacetic acid derivatives |
CA1304886C (en) | 1986-07-10 | 1992-07-07 | Heinz Dobeli | Metal chelate resins |
US5047513A (en) * | 1986-07-10 | 1991-09-10 | Hoffmann-La Roche Inc. | Metal chelate resins |
CA1340522C (en) † | 1987-03-10 | 1999-05-04 | Heinz Dobeli | Fusion proteins containing neighbouring histidines for improved purification |
US5061641A (en) | 1988-04-01 | 1991-10-29 | Immunomedics, Inc. | Method for radiolabeling proteins |
US5075099A (en) | 1988-05-31 | 1991-12-24 | Neorx Corporation | Metal radionuclide chelating compounds for improved chelation kinetics |
US5287933A (en) * | 1991-10-22 | 1994-02-22 | Caterpillar Pavin, Products Inc. | Hood support assembly for an earth working machine |
AU3328693A (en) | 1991-12-18 | 1993-07-19 | Advanced Oxygen Technologies, Inc. | Treatment of fungal infections |
JP3374442B2 (ja) | 1993-06-02 | 2003-02-04 | 株式会社豊田自動織機 | 自動車の外気導入装置 |
JP3704172B2 (ja) | 1993-10-25 | 2005-10-05 | 日本メジフィジックス株式会社 | キレート形成性フェニルジアミノジチオール誘導体及 びその用途 |
CA2111287C (en) † | 1993-12-13 | 2007-07-03 | Graham Darling | Chelating resins and use thereof in selectively recovering valuable metals from acid mine drainage |
US5990301A (en) | 1994-02-07 | 1999-11-23 | Qiagen Gmbh | Process for the separation and purification of nucleic acids from biological sources |
CA2182388C (en) | 1994-02-07 | 2007-08-07 | Metin Colpan | Process for producing endotoxin-free or endotoxin-poor nucleic acids and/or oligonucleotides for gene therapy |
DE4430023A1 (de) * | 1994-08-24 | 1996-02-29 | Boehringer Mannheim Gmbh | Elektrochemischer Sensor |
US5789578A (en) † | 1996-01-11 | 1998-08-04 | Massey University | Methods for the preparation of resins with ligands attached thereto through a linking group comprising sulfide, sulfoxide or sulfone functionality |
ZA975587B (en) † | 1996-06-24 | 1998-01-22 | Ibc Advanced Tech Inc | Poly N-cyclic aromatic ligands bonded to solid supports for removing and concentrating ions from solutions. |
JPH10182570A (ja) | 1996-12-27 | 1998-07-07 | Fuji Photo Film Co Ltd | アミノポリカルボン酸系キレート剤、その重金属化合物、写真用添加物、および処理方法 |
US6004529A (en) | 1997-04-11 | 1999-12-21 | Nycomed Imaging As | Chelating agents |
US6623655B1 (en) * | 2000-04-24 | 2003-09-23 | Sigma-Aldrich Co. | Metal chelating compositions |
-
2000
- 2000-04-24 US US09/558,001 patent/US6623655B1/en not_active Expired - Lifetime
-
2001
- 2001-04-10 WO PCT/US2001/011529 patent/WO2001081365A2/en active IP Right Grant
- 2001-04-10 AT AT01924862T patent/ATE298321T1/de not_active IP Right Cessation
- 2001-04-10 ES ES01924862T patent/ES2244609T5/es not_active Expired - Lifetime
- 2001-04-10 EP EP05013282A patent/EP1627683A3/de not_active Withdrawn
- 2001-04-10 AU AU2001251479A patent/AU2001251479A1/en not_active Abandoned
- 2001-04-10 JP JP2001578453A patent/JP4298201B2/ja not_active Expired - Lifetime
- 2001-04-10 DE DE60111628T patent/DE60111628T3/de not_active Expired - Lifetime
- 2001-04-10 EP EP01924862A patent/EP1276716B2/de not_active Expired - Lifetime
-
2003
- 2003-09-22 US US10/667,928 patent/US7033520B2/en not_active Expired - Lifetime
-
2006
- 2006-03-01 US US11/364,928 patent/US7709612B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
EP1276716B1 (de) | 2005-06-22 |
WO2001081365A2 (en) | 2001-11-01 |
JP4298201B2 (ja) | 2009-07-15 |
US20040092031A1 (en) | 2004-05-13 |
EP1627683A2 (de) | 2006-02-22 |
DE60111628T3 (de) | 2009-04-02 |
EP1627683A3 (de) | 2006-12-20 |
WO2001081365A3 (en) | 2002-03-28 |
ES2244609T5 (es) | 2009-03-16 |
ATE298321T1 (de) | 2005-07-15 |
AU2001251479A1 (en) | 2001-11-07 |
EP1276716B2 (de) | 2008-10-01 |
US20060148090A1 (en) | 2006-07-06 |
JP2003531213A (ja) | 2003-10-21 |
EP1276716A2 (de) | 2003-01-22 |
US7709612B2 (en) | 2010-05-04 |
US6623655B1 (en) | 2003-09-23 |
DE60111628T2 (de) | 2006-05-11 |
ES2244609T3 (es) | 2005-12-16 |
US7033520B2 (en) | 2006-04-25 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
ATE298321T1 (de) | Metallchelatisierende gemische | |
MY138525A (en) | Substituted acid derivatives useful as antidiabetic and antiobesity agents and method | |
PT1357111E (pt) | Derivados de 2-piridona com afinidade para receptores de canabinóides do tipo 2 | |
ATE108187T1 (de) | Protease-hemmer. | |
DK0446699T3 (da) | Inhibitorer af nitrogenoxid-biosyntese | |
DE60135764D1 (de) | Stickstoffhaltige, fünfgliedrige ringverbindungen | |
NZ511739A (en) | New esters derived from substituted phenyl-cyclohexyl compounds | |
EP0781835A4 (de) | Waschmittel | |
DK1310502T3 (da) | Phosphonocephem-forbindelse | |
DE69929877D1 (de) | BENZOCHINONDERIVATE ENTHALTENDE HEMMER VON NF-kB | |
SE8303912D0 (sv) | Jodvinylalkoholforening | |
BR9900788A (pt) | Compostos ésteres. | |
ATE271045T1 (de) | Sauerstoffhaltige heterocyclische verbindungen | |
FI971227A0 (fi) | Pyramidinyylipyratsolijohdannaisia | |
EP1306369A4 (de) | Neue schwefelverbindungen und intermolekulare verbindungen, die diese als komponente enthalten | |
DE60101639D1 (de) | Ein (1'R,2'S,5'R)-3-l-Menthoxypropan-1-ol, das eine kühlende Empfindung erzeugt | |
ES2188481T3 (es) | Derivados de polinalbufina. | |
PL308545A1 (en) | Novel substituted azethydinones as anti-inflammatory and anti-degenerative agents | |
AU1394802A (en) | Novel process | |
DE69319859D1 (de) | Neue tetracyclische verbindungen | |
DK1427741T3 (da) | Sammensætning | |
DK0953564T3 (da) | Fremgangsmåde til fremstilling af en 2-cyanobiphenylforbindelse | |
ATE108767T1 (de) | Acyclische terpene. | |
EP0659752A4 (de) | ||
ECSP951403A (es) | Compuestos heterociclicos y fenilo |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
8363 | Opposition against the patent | ||
8366 | Restricted maintained after opposition proceedings | ||
R082 | Change of representative |
Ref document number: 1276716 Country of ref document: EP Representative=s name: MAIWALD GMBH PATENTANWAELTE, DE |