DE60024312T2 - Transdermale Wirkstoffabgabe von makromolekularen Wirkstoffen und Vorrichtung hierfür - Google Patents

Transdermale Wirkstoffabgabe von makromolekularen Wirkstoffen und Vorrichtung hierfür Download PDF

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Publication number
DE60024312T2
DE60024312T2 DE60024312T DE60024312T DE60024312T2 DE 60024312 T2 DE60024312 T2 DE 60024312T2 DE 60024312 T DE60024312 T DE 60024312T DE 60024312 T DE60024312 T DE 60024312T DE 60024312 T2 DE60024312 T2 DE 60024312T2
Authority
DE
Germany
Prior art keywords
skin
body surface
microprojections
stretching
housing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60024312T
Other languages
German (de)
English (en)
Other versions
DE60024312D1 (de
Inventor
C. Joseph TRAUTMAN
J. Michel CORMIER
P. Kellee ENG
Wei-Qi Lin
L. Hyunok KIM
L. Sara SENDELBECK
P. Armand NEUKERMANS
P. Bruce EDWARDS
Wai-Loong Lim
I. Andrew POUTIATINE
Richard J. Gyory
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Alza Corp
Original Assignee
Alza Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alza Corp filed Critical Alza Corp
Application granted granted Critical
Publication of DE60024312D1 publication Critical patent/DE60024312D1/de
Publication of DE60024312T2 publication Critical patent/DE60024312T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/20—Surgical instruments, devices or methods, e.g. tourniquets for vaccinating or cleaning the skin previous to the vaccination
    • A61B17/205—Vaccinating by means of needles or other puncturing devices
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/0023—Drug applicators using microneedles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/0046—Solid microneedles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/42—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests having means for desensitising skin, for protruding skin to facilitate piercing, or for locating point where body is to be pierced
    • A61M5/425—Protruding skin to facilitate piercing, e.g. vacuum cylinders, vein immobilising means
DE60024312T 1999-12-10 2000-12-07 Transdermale Wirkstoffabgabe von makromolekularen Wirkstoffen und Vorrichtung hierfür Expired - Lifetime DE60024312T2 (de)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US17270399P 1999-12-10 1999-12-10
US172703P 1999-12-10
US21687700P 2000-07-07 2000-07-07
US216877P 2000-07-07
PCT/US2000/033318 WO2001041863A1 (en) 1999-12-10 2000-12-07 Device and method for enhancing microprotrusion skin piercing

Publications (2)

Publication Number Publication Date
DE60024312D1 DE60024312D1 (de) 2005-12-29
DE60024312T2 true DE60024312T2 (de) 2006-08-17

Family

ID=26868367

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60024312T Expired - Lifetime DE60024312T2 (de) 1999-12-10 2000-12-07 Transdermale Wirkstoffabgabe von makromolekularen Wirkstoffen und Vorrichtung hierfür

Country Status (10)

Country Link
US (2) US7087035B2 (da)
EP (1) EP1239916B1 (da)
AT (1) ATE310561T1 (da)
AU (1) AU2074301A (da)
CY (1) CY1105306T1 (da)
DE (1) DE60024312T2 (da)
DK (1) DK1239916T3 (da)
ES (1) ES2253278T3 (da)
HK (1) HK1048604B (da)
WO (1) WO2001041863A1 (da)

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Also Published As

Publication number Publication date
HK1048604B (zh) 2006-05-04
ATE310561T1 (de) 2005-12-15
US20050085766A1 (en) 2005-04-21
US7087035B2 (en) 2006-08-08
WO2001041863A1 (en) 2001-06-14
DE60024312D1 (de) 2005-12-29
EP1239916A1 (en) 2002-09-18
EP1239916B1 (en) 2005-11-23
DK1239916T3 (da) 2006-04-03
CY1105306T1 (el) 2010-03-03
ES2253278T3 (es) 2006-06-01
HK1048604A1 (en) 2003-04-11
US20020032415A1 (en) 2002-03-14
AU2074301A (en) 2001-06-18

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