CY1105306T1 - Διαταξη και μεθοδος για την ενισχυση της διατρησης δερματος μεσω μικροπροεξοχων - Google Patents

Διαταξη και μεθοδος για την ενισχυση της διατρησης δερματος μεσω μικροπροεξοχων

Info

Publication number
CY1105306T1
CY1105306T1 CY20061100252T CY061100252T CY1105306T1 CY 1105306 T1 CY1105306 T1 CY 1105306T1 CY 20061100252 T CY20061100252 T CY 20061100252T CY 061100252 T CY061100252 T CY 061100252T CY 1105306 T1 CY1105306 T1 CY 1105306T1
Authority
CY
Cyprus
Prior art keywords
skin
microprotrusions
enhancing skin
skin perforation
megapascals
Prior art date
Application number
CY20061100252T
Other languages
English (en)
Inventor
Joseph C. Trautman
Michel J. N. Cormier
Kellee P. Eng
Wei-Qi Lin
Hyunok L. Kim
Sara L. Sendelbeck
Armand P. Neukermans
Bruce P. Edwards
Wai-Loong Lim
Andrew I. Poutiatine
J. Richard Gyory
Original Assignee
Alza Corporation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alza Corporation filed Critical Alza Corporation
Publication of CY1105306T1 publication Critical patent/CY1105306T1/el

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/20—Surgical instruments, devices or methods, e.g. tourniquets for vaccinating or cleaning the skin previous to the vaccination
    • A61B17/205—Vaccinating by means of needles or other puncturing devices
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/0023—Drug applicators using microneedles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/0046—Solid microneedles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/42—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests having means for desensitising skin, for protruding skin to facilitate piercing, or for locating point where body is to be pierced
    • A61M5/425—Protruding skin to facilitate piercing, e.g. vacuum cylinders, vein immobilising means

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Surgery (AREA)
  • Medical Informatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Dermatology (AREA)
  • Anesthesiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Preparation (AREA)
  • Massaging Devices (AREA)
  • Media Introduction/Drainage Providing Device (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Διάταξη (100, 101, 102, 103, 104, 105, 106, 107) και μέθοδος για την ενίσχυση της διάτρησης δέρματος μέσω μικροπροεξοχών περιλαμβάνει προτέντωμα του δέρματος (30) για την ενίσχυση του σχηματισμού διόδων όταν οι μικροπροεξοχές (34) πιέζονται μέσα στο δέρμα. Εκτατη διάταξη (100) περιλαμβάνει αντίθετα άκρα (56, 57) συμπλεκόμενα με το δέρμα τα οποία έρχονται σε επαφή με την επιφάνεια του δέρματος (30) κατά τρόπο ώστε όταν η διάταξη (100) εκτείνεται το δέρμα (30) να τεντώνεται. Το δέρμα τίθεται υπό εφελκυσμό περίπου 0,01 έως περίπου 10 megapascals, κατά προτίμηση περίπου 0,05 έως 2 megapascals. Η διάταξη (100) φέρει πλήθος μικροπροεξοχών (34) οι οποίες διεισδύουν στο δέρμα (30), ενώ το δέρμα τεντώνεται από την εκτεινόμενη διάταξη (100) και προαιρετικώς κατά τη διάρκεια της χορήγησης κάποιου παράγοντα μέσω αυτού. Μία άλλη διάταξη τεντώματος (106) χρησιμοποιεί αναρρόφηση για το τέντωμα δέρματος.
CY20061100252T 1999-12-10 2006-02-22 Διαταξη και μεθοδος για την ενισχυση της διατρησης δερματος μεσω μικροπροεξοχων CY1105306T1 (el)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US17270399P 1999-12-10 1999-12-10
US21687700P 2000-07-07 2000-07-07
PCT/US2000/033318 WO2001041863A1 (en) 1999-12-10 2000-12-07 Device and method for enhancing microprotrusion skin piercing

Publications (1)

Publication Number Publication Date
CY1105306T1 true CY1105306T1 (el) 2010-03-03

Family

ID=26868367

Family Applications (1)

Application Number Title Priority Date Filing Date
CY20061100252T CY1105306T1 (el) 1999-12-10 2006-02-22 Διαταξη και μεθοδος για την ενισχυση της διατρησης δερματος μεσω μικροπροεξοχων

Country Status (10)

Country Link
US (2) US7087035B2 (el)
EP (1) EP1239916B1 (el)
AT (1) ATE310561T1 (el)
AU (1) AU2074301A (el)
CY (1) CY1105306T1 (el)
DE (1) DE60024312T2 (el)
DK (1) DK1239916T3 (el)
ES (1) ES2253278T3 (el)
HK (1) HK1048604B (el)
WO (1) WO2001041863A1 (el)

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ATE462468T1 (de) * 1999-06-04 2010-04-15 Georgia Tech Res Inst Vorrichtungen zur vergrösserten penetration von mikronadeln in biologischen hautschichten

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EP1239916B1 (en) 2005-11-23
EP1239916A1 (en) 2002-09-18
ES2253278T3 (es) 2006-06-01
HK1048604B (zh) 2006-05-04
AU2074301A (en) 2001-06-18
DE60024312D1 (de) 2005-12-29
US20050085766A1 (en) 2005-04-21
DE60024312T2 (de) 2006-08-17
WO2001041863A1 (en) 2001-06-14
HK1048604A1 (en) 2003-04-11
US20020032415A1 (en) 2002-03-14
DK1239916T3 (da) 2006-04-03
US7087035B2 (en) 2006-08-08

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