DE60023905D1 - Optisches system analyse für zellen - Google Patents

Optisches system analyse für zellen

Info

Publication number
DE60023905D1
DE60023905D1 DE60023905T DE60023905T DE60023905D1 DE 60023905 D1 DE60023905 D1 DE 60023905D1 DE 60023905 T DE60023905 T DE 60023905T DE 60023905 T DE60023905 T DE 60023905T DE 60023905 D1 DE60023905 D1 DE 60023905D1
Authority
DE
Germany
Prior art keywords
cells
optical system
system analysis
kits
screens
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60023905T
Other languages
English (en)
Other versions
DE60023905T2 (de
Inventor
Richik Ghosh
L Debiasio
Prem Janardhan
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Cellomics Inc
Original Assignee
Cellomics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cellomics Inc filed Critical Cellomics Inc
Application granted granted Critical
Publication of DE60023905D1 publication Critical patent/DE60023905D1/de
Publication of DE60023905T2 publication Critical patent/DE60023905T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1034—Isolating an individual clone by screening libraries
    • C12N15/1089—Design, preparation, screening or analysis of libraries using computer algorithms
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/5082—Supracellular entities, e.g. tissue, organisms
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N15/1429—Signal processing
    • G01N15/1433—Signal processing using image recognition

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Organic Chemistry (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Wood Science & Technology (AREA)
  • Cell Biology (AREA)
  • Plant Pathology (AREA)
  • Pathology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Biophysics (AREA)
  • General Physics & Mathematics (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Toxicology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
DE60023905T 1999-08-05 2000-08-04 Optische Systemanalyse von Zellen Expired - Lifetime DE60023905T2 (de)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
US14744399P 1999-08-05 1999-08-05
US147443P 1999-08-05
US39896599A 1999-09-17 1999-09-17
US398965 1999-09-17
US17658900P 2000-01-18 2000-01-18
US176589P 2000-01-18
US20569600P 2000-05-19 2000-05-19
US205696P 2000-05-19
PCT/US2000/021416 WO2001011340A1 (en) 1999-08-05 2000-08-04 Optical system analysis of cells

Publications (2)

Publication Number Publication Date
DE60023905D1 true DE60023905D1 (de) 2005-12-15
DE60023905T2 DE60023905T2 (de) 2006-07-27

Family

ID=27495764

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60023905T Expired - Lifetime DE60023905T2 (de) 1999-08-05 2000-08-04 Optische Systemanalyse von Zellen

Country Status (8)

Country Link
EP (1) EP1203214B1 (de)
JP (2) JP2003506711A (de)
AT (1) ATE309528T1 (de)
AU (1) AU6522300A (de)
CA (1) CA2381344C (de)
DE (1) DE60023905T2 (de)
IL (1) IL147793A0 (de)
WO (1) WO2001011340A1 (de)

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US5989835A (en) 1997-02-27 1999-11-23 Cellomics, Inc. System for cell-based screening
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US6986993B1 (en) 1999-08-05 2006-01-17 Cellomics, Inc. System for cell-based screening
AU2073801A (en) 1999-12-09 2001-06-18 Cellomics, Inc. A system for cell-based screening
WO2002041064A1 (en) 2000-11-17 2002-05-23 Universal Imaging Corporation Rapidly changing dichroic beamsplitter
ATE267396T1 (de) 2000-12-22 2004-06-15 Cellomics Inc Identifizierung von zellen während kinetischer versuchsreihen
US6636623B2 (en) * 2001-08-10 2003-10-21 Visiongate, Inc. Optical projection imaging system and method for automatically detecting cells with molecular marker compartmentalization associated with malignancy and disease
US8227240B2 (en) 2001-08-14 2012-07-24 The Washington University Systems for screening pharmaceutical chemicals
JP2003093041A (ja) * 2001-09-25 2003-04-02 Hamamatsu Photonics Kk 培養試料観察装置
AU2002357791B9 (en) * 2001-12-05 2008-09-25 The J. David Gladstone Institutes Robotic microscopy systems
AU2003230069B2 (en) * 2002-05-14 2008-11-13 Molecular Devices, Llc System and methods for rapid and automated screening of cells
GB0211072D0 (en) * 2002-05-15 2002-06-26 Amersham Biosciences Uk Ltd Reagent and method for the determination of changes in a cellular morphological parameter
JP3908135B2 (ja) * 2002-09-09 2007-04-25 オリンパス株式会社 生化学的検査用画像処理方法
AU2003900924A0 (en) 2003-02-28 2003-03-13 Medsaic Pty Ltd Imaging device
GB0317679D0 (en) * 2003-07-29 2003-09-03 Amersham Biosciences Uk Ltd Analysing biological entities
WO2005039396A2 (en) * 2003-10-22 2005-05-06 Medtrain Technologies, Llc Tissue engineered construct analytical imaging system and method of obtaining and analyzing images of tissue engineered constructs
CA2572390A1 (en) * 2004-06-30 2006-08-31 Chemimage Corporation Spectroscopic methods for component particle analysis
CN101268355A (zh) * 2005-09-21 2008-09-17 卢米尼克斯股份有限公司 图像数据处理的方法和系统
US8149416B2 (en) 2005-10-17 2012-04-03 Arryx, Inc. Apparatus and method for dynamic cellular probing and diagnostics using holographic optical forcing array
WO2007047761A1 (en) * 2005-10-17 2007-04-26 Arryx, Inc. Apparatus and method for detecting deformability of cells using spatially modulated optical force microscopy
JPWO2007069414A1 (ja) 2005-12-14 2009-05-21 国立大学法人 東京大学 線状の形態を有する細胞等を解析する方法及び神経細胞解析方法並びにそれら方法を実行する装置及びプログラム
JP2007248050A (ja) * 2006-02-17 2007-09-27 Olympus Corp 生細胞の微弱光による解析を行なうための細胞の処理方法および解析方法
CN101484806A (zh) 2006-05-17 2009-07-15 协乐民公司 一种对组织进行自动分析的方法
US7706591B2 (en) 2006-07-13 2010-04-27 Cellomics, Inc. Neuronal profiling
US8326014B2 (en) * 2007-09-28 2012-12-04 Cytyc Corporation Methods and systems for processing biological specimens utilizing multiple wavelengths
ITTO20070771A1 (it) * 2007-10-29 2009-04-30 Silicon Biosystems Spa Metodo e apparato per la identificazione e manipolazione di particelle
CA2726979C (en) 2008-06-05 2017-11-28 Medical College Of Wisconsin, Inc. Three dimensional tissues for high-throughput assays
IT1391619B1 (it) 2008-11-04 2012-01-11 Silicon Biosystems Spa Metodo per l'individuazione, selezione e analisi di cellule tumorali
US10895575B2 (en) 2008-11-04 2021-01-19 Menarini Silicon Biosystems S.P.A. Method for identification, selection and analysis of tumour cells
JP5478084B2 (ja) * 2009-01-23 2014-04-23 オリンパス株式会社 画像処理システム、画像処理装置および画像処理端末
US9567560B2 (en) * 2009-02-26 2017-02-14 National University Corporation Nagoya University Incubated state evaluating device, incubated state evaluating method, incubator, and program
DE102009021876A1 (de) 2009-05-19 2010-11-25 Forschungsgesellschaft für Arbeitsphysiologie und Arbeitsschutz e.V. Verfahren zur Analyse des Neuritenwachstums
EP2433123A1 (de) * 2009-05-19 2012-03-28 Leibniz - Institut für Analytische Wissenschaften - ISAS - E.V. Verfahren zur analyse des neuritenwachstums
DE102010035003B4 (de) * 2010-08-20 2015-08-06 PicoQuant GmbH. Unternehmen für optoelektronische Forschung und Entwicklung Räumlich und zeitlich hochauflösende Mikroskopie
CA2830501C (en) 2011-03-17 2023-10-17 Cernostics, Inc. Systems and compositions for diagnosing barrett's esophagus and methods of using the same
JP5720351B2 (ja) * 2011-03-24 2015-05-20 横河電機株式会社 画像解析方法および画像解析装置
JP5873183B2 (ja) * 2011-10-18 2016-03-01 ルミネックス コーポレーション 画像データ処理方法及びシステム
CH706326A2 (de) * 2012-03-14 2013-09-30 Tecan Trading Ag Verfahren und Mikroplatten-Reader zum Untersuchung von biologischen Zellen oder Zellkulturen.
WO2014093838A2 (en) 2012-12-14 2014-06-19 The J. David Gladstone Institutes Automated robotic microscopy systems
JP5639670B2 (ja) 2013-02-01 2014-12-10 浜松ホトニクス株式会社 画像取得装置及び撮像装置
JP6467813B2 (ja) 2014-08-15 2019-02-13 ソニー株式会社 画像処理装置、画像処理プログラム及び画像処理方法
JP6684643B2 (ja) * 2016-04-28 2020-04-22 富士フイルム株式会社 生体試料評価システムおよび生体試料評価方法並びに生体試料評価制御プログラム
JP7316745B2 (ja) * 2016-05-20 2023-07-28 株式会社リコー 三次元組織体
JP7407107B2 (ja) * 2017-11-10 2023-12-28 ザルトリウス バイオアナリティカル インストゥルメンツ， インコーポレイテッド 生細胞の視覚化及び分析
JP6986452B2 (ja) * 2018-01-04 2021-12-22 浜松ホトニクス株式会社 蛍光測定装置および蛍光測定方法
WO2019245005A1 (ja) * 2018-06-20 2019-12-26 株式会社 東芝 検査デバイス、この検査デバイスの製造方法、この検査デバイスを用いた細胞検出方法、この検査デバイス用セル、この検査デバイス用セルの製造方法、及び検査方法
JP7158220B2 (ja) * 2018-09-11 2022-10-21 浜松ホトニクス株式会社 測定装置および測定方法
US10564100B1 (en) * 2018-10-12 2020-02-18 SageMedic Corporation Analysis of viable and nonviable cells
DE102020202610B4 (de) 2020-02-28 2021-09-23 Gottfried Wilhelm Leibniz Universität Hannover Verfahren und Vorrichtung zur automatisierten mikroskopischen Analyse von nervenzellhaltigen Proben
CN111832191B (zh) * 2020-07-29 2023-06-30 南开大学 基于生长域的微管内增量式细胞质速度场评估方法
DE102020122605A1 (de) 2020-08-28 2022-03-03 Abberior Instruments Gmbh Verfahren, Bildverarbeitungseinheit und Laserscanningmikroskop zum hintergrundreduzierten Abbilden einer Struktur in einer Probe
JP7235027B2 (ja) * 2020-11-16 2023-03-08 株式会社ニコン 細胞評価装置、インキュベータおよびプログラム

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US4998284A (en) * 1987-11-17 1991-03-05 Cell Analysis Systems, Inc. Dual color camera microscope and methodology for cell staining and analysis
US6060247A (en) * 1996-11-18 2000-05-09 Mcgill University Post-mitotic neurons containing adenovirus vectors that modulate apoptosis and growth
CA2282658C (en) * 1997-02-27 2003-02-25 Cellomics, Inc. A system for cell-based screening
AU745911B2 (en) * 1997-07-17 2002-04-11 Myelos Corporation Prosaposin receptor assay

Also Published As

Publication number Publication date
JP2005095172A (ja) 2005-04-14
ATE309528T1 (de) 2005-11-15
CA2381344C (en) 2007-01-23
DE60023905T2 (de) 2006-07-27
EP1203214A1 (de) 2002-05-08
AU6522300A (en) 2001-03-05
EP1203214B1 (de) 2005-11-09
JP2003506711A (ja) 2003-02-18
JP4693382B2 (ja) 2011-06-01
CA2381344A1 (en) 2001-02-15
IL147793A0 (en) 2002-08-14
WO2001011340A1 (en) 2001-02-15

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