DE3923279A1 - Minusheets ist ein neues produkt, um zellen in beliebigen behaeltnissen in hochdifferenzierter form auf einer moeglichst natuerlichen unterlage zu kultivieren - Google Patents
Minusheets ist ein neues produkt, um zellen in beliebigen behaeltnissen in hochdifferenzierter form auf einer moeglichst natuerlichen unterlage zu kultivierenInfo
- Publication number
- DE3923279A1 DE3923279A1 DE3923279A DE3923279A DE3923279A1 DE 3923279 A1 DE3923279 A1 DE 3923279A1 DE 3923279 A DE3923279 A DE 3923279A DE 3923279 A DE3923279 A DE 3923279A DE 3923279 A1 DE3923279 A1 DE 3923279A1
- Authority
- DE
- Germany
- Prior art keywords
- cells
- minus
- minusheets
- sheet
- sheets
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 238000002474 experimental method Methods 0.000 claims description 13
- 230000010412 perfusion Effects 0.000 claims description 11
- 238000004113 cell culture Methods 0.000 claims description 7
- 239000012876 carrier material Substances 0.000 claims description 4
- 230000001413 cellular effect Effects 0.000 claims description 2
- 238000012986 modification Methods 0.000 claims description 2
- 230000004048 modification Effects 0.000 claims description 2
- 230000001419 dependent effect Effects 0.000 claims 1
- 239000000126 substance Substances 0.000 claims 1
- 210000004027 cell Anatomy 0.000 description 36
- 238000000034 method Methods 0.000 description 7
- 102000010834 Extracellular Matrix Proteins Human genes 0.000 description 6
- 108010037362 Extracellular Matrix Proteins Proteins 0.000 description 6
- 210000002744 extracellular matrix Anatomy 0.000 description 6
- 239000000463 material Substances 0.000 description 6
- 238000000576 coating method Methods 0.000 description 5
- 238000005516 engineering process Methods 0.000 description 5
- 238000004519 manufacturing process Methods 0.000 description 5
- 230000008901 benefit Effects 0.000 description 4
- 210000004748 cultured cell Anatomy 0.000 description 4
- 230000004069 differentiation Effects 0.000 description 4
- 102000008186 Collagen Human genes 0.000 description 3
- 108010035532 Collagen Proteins 0.000 description 3
- 239000011248 coating agent Substances 0.000 description 3
- 229920001436 collagen Polymers 0.000 description 3
- 230000008569 process Effects 0.000 description 3
- 230000028327 secretion Effects 0.000 description 3
- 230000010261 cell growth Effects 0.000 description 2
- 238000011161 development Methods 0.000 description 2
- 230000018109 developmental process Effects 0.000 description 2
- 239000011521 glass Substances 0.000 description 2
- 230000012010 growth Effects 0.000 description 2
- 238000012546 transfer Methods 0.000 description 2
- 230000032258 transport Effects 0.000 description 2
- 241000761427 Boraras micros Species 0.000 description 1
- 240000004385 Centaurea cyanus Species 0.000 description 1
- 102000016359 Fibronectins Human genes 0.000 description 1
- 108010067306 Fibronectins Proteins 0.000 description 1
- 102000007547 Laminin Human genes 0.000 description 1
- 108010085895 Laminin Proteins 0.000 description 1
- 241000208967 Polygala cruciata Species 0.000 description 1
- 101710137510 Saimiri transformation-associated protein Proteins 0.000 description 1
- 230000002411 adverse Effects 0.000 description 1
- 238000004873 anchoring Methods 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 230000024245 cell differentiation Effects 0.000 description 1
- 230000008859 change Effects 0.000 description 1
- 239000006059 cover glass Substances 0.000 description 1
- 238000005520 cutting process Methods 0.000 description 1
- 239000011888 foil Substances 0.000 description 1
- 239000001963 growth medium Substances 0.000 description 1
- 208000015181 infectious disease Diseases 0.000 description 1
- 238000003780 insertion Methods 0.000 description 1
- 230000037431 insertion Effects 0.000 description 1
- 210000003734 kidney Anatomy 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 229940050561 matrix product Drugs 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 238000004806 packaging method and process Methods 0.000 description 1
- 238000004080 punching Methods 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- 238000007789 sealing Methods 0.000 description 1
- 239000002689 soil Substances 0.000 description 1
- 230000006641 stabilisation Effects 0.000 description 1
- 238000011105 stabilization Methods 0.000 description 1
- 239000000758 substrate Substances 0.000 description 1
- 238000012360 testing method Methods 0.000 description 1
- 210000003454 tympanic membrane Anatomy 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M25/00—Means for supporting, enclosing or fixing the microorganisms, e.g. immunocoatings
- C12M25/02—Membranes; Filters
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M23/00—Constructional details, e.g. recesses, hinges
- C12M23/44—Multiple separable units; Modules
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M25/00—Means for supporting, enclosing or fixing the microorganisms, e.g. immunocoatings
- C12M25/14—Scaffolds; Matrices
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M29/00—Means for introduction, extraction or recirculation of materials, e.g. pumps
- C12M29/10—Perfusion
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical & Material Sciences (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Sustainable Development (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Immunology (AREA)
- Clinical Laboratory Science (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE3923279A DE3923279A1 (de) | 1989-07-14 | 1989-07-14 | Minusheets ist ein neues produkt, um zellen in beliebigen behaeltnissen in hochdifferenzierter form auf einer moeglichst natuerlichen unterlage zu kultivieren |
| US07/627,729 US5190878A (en) | 1989-07-14 | 1990-12-14 | Apparatus for cultivating cells |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE3923279A DE3923279A1 (de) | 1989-07-14 | 1989-07-14 | Minusheets ist ein neues produkt, um zellen in beliebigen behaeltnissen in hochdifferenzierter form auf einer moeglichst natuerlichen unterlage zu kultivieren |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE3923279A1 true DE3923279A1 (de) | 1990-01-18 |
| DE3923279C2 DE3923279C2 (enExample) | 1991-01-31 |
Family
ID=6385013
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE3923279A Granted DE3923279A1 (de) | 1989-07-14 | 1989-07-14 | Minusheets ist ein neues produkt, um zellen in beliebigen behaeltnissen in hochdifferenzierter form auf einer moeglichst natuerlichen unterlage zu kultivieren |
Country Status (2)
| Country | Link |
|---|---|
| US (1) | US5190878A (enExample) |
| DE (1) | DE3923279A1 (enExample) |
Cited By (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1992020780A1 (de) * | 1991-05-17 | 1992-11-26 | Uwe Marx | Verfahren und vorrichtung zur gleichzeitigen kultivierung unterschiedlicher säugerzellen |
| DE4305405C1 (de) * | 1993-02-22 | 1994-05-26 | Hering Steffen Dr Sc Med | Vorrichtung zum Untersuchen eines Objekts, das sich in einer ein Substrat bedeckenden Perfusionsflüssigkeit befindet |
| WO1991018653A3 (en) * | 1990-06-04 | 1994-08-18 | Molecular Devices Corp | Cell assay device |
| WO1996003094A1 (de) * | 1994-07-25 | 1996-02-08 | W.L. Gore & Associates Gmbh | Membran zur regeneration von körpergeweben und verwendung der membran als wundabdeckung und hautersatz |
| FR2735496A1 (fr) * | 1995-06-15 | 1996-12-20 | Chemodyne Sa | Nouveau dispositif de culture de cellules et les tissus ainsi recoltes |
| DE19818425A1 (de) * | 1997-10-18 | 1999-07-15 | Malte Dr Med Boehm | Vorrichtung zur Handhabung von Proben für die membrangestützte Mikrodissektion |
| AT407047B (de) * | 1998-08-03 | 2000-11-27 | Pfaller Walter Dr | Zellkulturvorrichtung |
| EP0926480A3 (de) * | 1997-10-18 | 2001-08-16 | Malte Dr. Böhm | Vorrichtung zur Handhabung von Proben für die membrangestützte Mikrodissektion |
| WO2005113743A3 (de) * | 2004-05-19 | 2006-06-15 | Univ Rostock | Vorrichtung zur durchführung einer liquid-air-kultur von epithel |
| DE102010023794A1 (de) | 2010-04-09 | 2011-10-13 | Stefan Neumeyer | Medizinisches, insbesondere zahnmedizinisches Substrat |
| WO2012085268A3 (de) * | 2010-12-23 | 2012-08-30 | Universität Rostock | Zellreaktor |
| WO2013117193A1 (de) | 2012-02-09 | 2013-08-15 | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e. V. | Stimulationszelle und verfahren zur in vitro stimulation von zellen oder geweben |
| WO2015169287A1 (de) * | 2014-05-08 | 2015-11-12 | Universitätsklinikum Jena | Verfahren und vorrichtungen zur in-vitro-herstellung von anordnungen von zellschichten |
Families Citing this family (88)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5763266A (en) * | 1989-06-15 | 1998-06-09 | The Regents Of The University Of Michigan | Methods, compositions and devices for maintaining and growing human stem and/or hematopoietics cells |
| US5726060A (en) * | 1991-09-17 | 1998-03-10 | Bridges; Michael Anthony | Method for culturing mammalian respiratory epithelial cells |
| US6066496A (en) * | 1991-09-17 | 2000-05-23 | Bridges; Michael Anthony | Apparatus for culturing mammalian respiratory epithelial |
| US5514555A (en) * | 1993-03-12 | 1996-05-07 | Center For Blood Research, Inc. | Assays and therapeutic methods based on lymphocyte chemoattractants |
| US5599688A (en) * | 1993-10-18 | 1997-02-04 | Precision Instrument Design | Device and method for circulating fluid over a membrane |
| US5591636A (en) * | 1993-10-18 | 1997-01-07 | Precision Instrument Design | Membrane holder |
| US5595866A (en) * | 1994-05-27 | 1997-01-21 | Methodist Hospital Of Indiana, Inc. | Step-wise method to remove cryoprotectant from sperm |
| US6054287A (en) * | 1994-05-27 | 2000-04-25 | Methodist Hospital Of Indiana, Inc. | Cell-type-specific methods and devices for the low temperature preservation of the cells of an animal species |
| US5635396A (en) * | 1995-08-30 | 1997-06-03 | Becton, Dickinson And Company | Coverslip holder |
| GB9700840D0 (en) * | 1997-01-16 | 1997-03-05 | Smith & Nephew | Cell-culture system |
| DE19721477A1 (de) * | 1997-05-23 | 1998-11-26 | Abb Patent Gmbh | Mikrobieller Membranreaktor zur Verwendung in Fließsystemen |
| DE19808055B4 (de) * | 1998-02-27 | 2007-02-08 | Adamietz, Peter, Dr.rer.nat. | Verfahren und Apparatur zur Herstellung von dreidimensionalen Gewebezellkulturen |
| ATE227338T1 (de) | 1998-03-18 | 2002-11-15 | Massachusetts Inst Technology | Vaskularisierte perfundierte anordnungen für mikrogewebe und mikroorgane |
| US6146883A (en) * | 1998-09-14 | 2000-11-14 | Navicyte, Inc. | Packing device for transporting confluent cell monolayers |
| AU3306300A (en) * | 1999-03-17 | 2000-10-04 | Biodiversity Limited | Biochemical synthesis apparatus |
| US6562616B1 (en) * | 1999-06-21 | 2003-05-13 | The General Hospital Corporation | Methods and devices for cell culturing and organ assist systems |
| AU5756700A (en) | 1999-06-21 | 2001-01-09 | General Hospital Corporation, The | Cell culture systems and methods for organ assist devices |
| DE19932439C2 (de) * | 1999-07-12 | 2002-06-13 | Sefar Ag Rueschlikon | Bioreaktor |
| US6867041B2 (en) | 2000-02-24 | 2005-03-15 | Xcyte Therapies, Inc. | Simultaneous stimulation and concentration of cells |
| US20030119185A1 (en) * | 2000-02-24 | 2003-06-26 | Xcyte Therapies, Inc. | Activation and expansion of cells |
| US7572631B2 (en) * | 2000-02-24 | 2009-08-11 | Invitrogen Corporation | Activation and expansion of T cells |
| DK1257632T3 (da) | 2000-02-24 | 2008-01-28 | Xcyte Therapies Inc | Samtidig stimulering og opkoncentrering af celler |
| US20030235908A1 (en) * | 2000-02-24 | 2003-12-25 | Xcyte Therapies, Inc. | Activation and expansion of cells |
| US6797514B2 (en) | 2000-02-24 | 2004-09-28 | Xcyte Therapies, Inc. | Simultaneous stimulation and concentration of cells |
| US7541184B2 (en) | 2000-02-24 | 2009-06-02 | Invitrogen Corporation | Activation and expansion of cells |
| FR2808283B1 (fr) | 2000-04-27 | 2002-12-20 | Cell Tissue Progress | Unite de culture de cellules et tissus a configuration variable |
| US20020019048A1 (en) * | 2000-05-25 | 2002-02-14 | Ronald Berenson | Methods for restoring or enhancing T-cell immune surveillance following naturally or artificially induced immunosuppression |
| KR100394247B1 (ko) * | 2001-02-05 | 2003-08-06 | 주식회사 케이티앤지 | 세포 배양기 |
| AU2002367057B2 (en) * | 2001-12-21 | 2007-01-11 | Organogenesis Inc. | Chamber with adjustable volume for cell culture and organ assist |
| US7745140B2 (en) | 2002-01-03 | 2010-06-29 | The Trustees Of The University Of Pennsylvania | Activation and expansion of T-cells using an engineered multivalent signaling platform as a research tool |
| WO2003057171A2 (en) * | 2002-01-03 | 2003-07-17 | The Trustees Of The University Of Pennsylvania | Activation and expansion of t-cells using an engineered multivalent signaling platform |
| US7638326B2 (en) | 2002-01-03 | 2009-12-29 | The Trustees Of The University Of Pennsylvania | Activation and expansion of T-cells using an engineered multivalent signaling platform |
| US20030215941A1 (en) * | 2002-03-12 | 2003-11-20 | Stewart Campbell | Assay device that analyzes the absorption, metabolism, permeability and/or toxicity of a candidate compound |
| US20050084967A1 (en) * | 2002-06-28 | 2005-04-21 | Xcyte Therapies, Inc. | Compositions and methods for eliminating undesired subpopulations of T cells in patients with immunological defects related to autoimmunity and organ or hematopoietic stem cell transplantation |
| US20040175373A1 (en) * | 2002-06-28 | 2004-09-09 | Xcyte Therapies, Inc. | Compositions and methods for eliminating undesired subpopulations of T cells in patients with immunological defects related to autoimmunity and organ or hematopoietic stem cell transplantation |
| AU2003253684A1 (en) * | 2002-06-28 | 2004-01-19 | Xcyte Therapies, Inc. | Compositions and methods for restoring immune repertoire in patients with immunological defects related to autoimmunity and organ or hematopoietic stem cell transplantation |
| WO2004076608A2 (en) * | 2003-02-26 | 2004-09-10 | Georgia Tech Research Corporation | Bioreactor and methods for tissue growth and conditioning |
| DK1623017T3 (da) * | 2003-05-08 | 2011-01-10 | Life Technologies Corp | Frembringelse og isolering af antigenspecifikke T-celler |
| US20050118173A1 (en) * | 2003-09-22 | 2005-06-02 | Xcyte Therapies, Inc. | Compositions and methods to accelerate hematologic recovery |
| DE102004017476B4 (de) * | 2004-04-08 | 2009-03-26 | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. | Verfahren zur Herstellung einer Epithelzellen enthaltenden Zellzusammensetzung |
| JP2007537759A (ja) * | 2004-05-19 | 2007-12-27 | マサチューセッツ・インスティテュート・オブ・テクノロジー | 灌流三次元細胞/組織疾患モデル |
| ES2653570T3 (es) | 2004-05-27 | 2018-02-07 | The Trustees Of The University Of Pennsylvania | Células presentadoras de antígeno artificiales novedosas y usos de las mismas |
| US6987019B1 (en) * | 2004-09-03 | 2006-01-17 | Vitaly Rogalsky | Device for growing cells |
| US7368279B2 (en) * | 2004-11-24 | 2008-05-06 | The Regents Of The University Of Michigan | Three dimensional bioengineered smooth muscle tissue and sphincters and methods therefor |
| US7927867B2 (en) * | 2005-03-31 | 2011-04-19 | Cascade Life Sciences, Inc. | Device for evaluating in vitro cell migration under flow conditions, and methods of use thereof |
| US8865460B2 (en) * | 2005-08-12 | 2014-10-21 | Clemson University Research Foundation | Co-culture bioreactor system |
| ZA200602094B (en) * | 2006-01-16 | 2007-11-28 | Reliance Life Sciences Pvt Ltd | Device for culturing and transporting cells |
| DE102007034935B4 (de) * | 2006-07-24 | 2014-07-17 | Biocer Entwicklungs Gmbh | Anordnung für Online-Messungen an Zellen |
| US9309491B2 (en) * | 2007-05-29 | 2016-04-12 | Corning Incorporated | Cell culture apparatus for co-culture of cells |
| US8808541B2 (en) | 2008-03-03 | 2014-08-19 | Marwan Nasralla | Dialysis cell and tray for dialysis cells |
| AT506826B1 (de) * | 2008-05-23 | 2010-03-15 | Greiner Bio One Gmbh | Bioreaktor und verfahren zum kultivieren von zellen und geweben |
| US9226494B2 (en) * | 2008-09-19 | 2016-01-05 | University Of Louisville Research Foundation, Inc. | Bioreactors, systems, and methods for vascularizing tissue constructs |
| US9249383B2 (en) * | 2008-10-08 | 2016-02-02 | Agency For Science Technology & Research | Apparatus for culturing anchorage dependent cells |
| WO2010048417A2 (en) * | 2008-10-22 | 2010-04-29 | Biovest International, Inc. | Perfusion bioreactors, cell culture systems, and methods for production of cells and cell-derived products |
| US20110229961A1 (en) * | 2008-11-05 | 2011-09-22 | Nanopoint, Inc. | Active microfluidic system for in vitro culture |
| US9228579B2 (en) * | 2008-12-19 | 2016-01-05 | Stobbe Tech A/S | Method and device for industrial biolayer cultivation |
| WO2010148275A2 (en) * | 2009-06-18 | 2010-12-23 | Kiyatec, Llc | Bioreactor system |
| ITTO20090798A1 (it) * | 2009-10-21 | 2011-04-22 | Techfab S R L | Dispositivo e metodo per la manipolazione di particelle in sospensione e tessuti cellulari |
| US10745467B2 (en) | 2010-03-26 | 2020-08-18 | The Trustees Of Dartmouth College | VISTA-Ig for treatment of autoimmune, allergic and inflammatory disorders |
| CA2794483C (en) | 2010-03-26 | 2020-07-07 | Trustees Of Dartmouth College | Vista regulatory t cell mediator protein, vista binding agents and use thereof |
| US20150231215A1 (en) | 2012-06-22 | 2015-08-20 | Randolph J. Noelle | VISTA Antagonist and Methods of Use |
| AU2011252063A1 (en) * | 2010-05-11 | 2012-11-29 | Pall Artelis | Apparatus and methods for cell culture |
| WO2012003465A2 (en) | 2010-07-01 | 2012-01-05 | The Regents Of The University Of Michigan | Scaffold-free three dimensional nerve fibroblast constructs |
| DE102011057045A1 (de) * | 2011-12-23 | 2013-06-27 | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. | Monitoringzelle und Verfahren zur Analyse eines Zell- und Gewebewachstums |
| US11311367B2 (en) | 2012-01-31 | 2022-04-26 | Wake Forest University Health Sciences | Tissue-engineered gut-sphincter complexes and methods of making the same |
| EP2817330B1 (en) | 2012-02-22 | 2020-07-08 | The Trustees of the University of Pennsylvania | Use of icos-based cars to enhance antitumor activity and car persistence |
| TWI677507B (zh) | 2012-06-22 | 2019-11-21 | 達特茅斯學院基金會 | 新穎之vista-ig構築體及vista-ig用於治療自體免疫、過敏及發炎病症之用途 |
| US9890215B2 (en) | 2012-06-22 | 2018-02-13 | King's College London | Vista modulators for diagnosis and treatment of cancer |
| EP2892558B1 (en) | 2012-09-07 | 2019-04-10 | The Trustees Of Dartmouth College | Vista modulators for diagnosis and treatment of cancer |
| WO2014152906A2 (en) | 2013-03-14 | 2014-09-25 | Research Institute At Nationwide Children's Hospital, Inc. | Tissue engineered intestine |
| US20150147771A1 (en) * | 2013-11-22 | 2015-05-28 | Cleveland State University | Microperfusion tissue interrogator |
| CN119775416A (zh) | 2013-12-24 | 2025-04-08 | 杨森制药公司 | 抗vista抗体及片段 |
| US11014987B2 (en) | 2013-12-24 | 2021-05-25 | Janssen Pharmaceutics Nv | Anti-vista antibodies and fragments, uses thereof, and methods of identifying same |
| CN106103691A (zh) * | 2014-04-14 | 2016-11-09 | 株式会社岛津制作所 | 细胞培养用设备、细胞培养用系统及细胞培养方法 |
| JP6997619B2 (ja) | 2014-06-11 | 2022-01-17 | キャシー・エイ・グリーン | 液性免疫の抑制または増進のための、vistaアゴニスト及びvistaアンタゴニストの使用 |
| US20170209492A1 (en) | 2014-07-31 | 2017-07-27 | Novartis Ag | Subset-optimized chimeric antigen receptor-containing t-cells |
| AU2015357463B2 (en) | 2014-12-05 | 2021-10-07 | Immunext, Inc. | Identification of VSIG8 as the putative vista receptor and its use thereof to produce vista/VSIG8 modulators |
| EP3722314A1 (en) | 2015-06-24 | 2020-10-14 | Janssen Pharmaceutica NV | Anti-vista antibodies and fragments |
| EP3325964A1 (en) * | 2015-07-17 | 2018-05-30 | Lawrence M. Boyd | Apparatus and method for sorting of cells |
| US10227556B2 (en) | 2015-09-04 | 2019-03-12 | Wayne State University | Cell culture devices for biomimetic and pathomimetic cell cultures |
| US20170158999A1 (en) * | 2015-12-03 | 2017-06-08 | The Government Of The United States Of America, As Represented By The Secretary Of The Navy | Modular bioreactor for culture of biopaper based tissues |
| US20190015190A1 (en) | 2015-12-30 | 2019-01-17 | Wake Forest University Health Sciences | Tissue-engineered gut-sphincter complexes and methods of making the same |
| MX2018009800A (es) | 2016-02-12 | 2018-11-09 | Janssen Pharmaceutica Nv | Anticuerpos y fragmentos anti-vista, usos de los mismos y procedimientos de identificacion de los mismos. |
| EP3448412A4 (en) | 2016-04-15 | 2020-03-25 | Immunext Inc. | ANTI-HUMAN-VISTA ANTIBODIES AND USE THEREOF |
| CN115044471B (zh) | 2016-08-27 | 2025-05-27 | 三维生物科技有限公司 | 生物反应器 |
| US10247724B1 (en) | 2017-09-28 | 2019-04-02 | Autobiologic Inc. | Optically clear sealable petri dish bioreactor |
| WO2021075502A1 (ja) * | 2019-10-16 | 2021-04-22 | 国立研究開発法人理化学研究所 | 細胞シート製造装置、および細胞シート |
| WO2023152489A1 (en) * | 2022-02-08 | 2023-08-17 | Ivy Farm Technologies Limited | Bioreactor |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4608342A (en) * | 1983-05-13 | 1986-08-26 | Stephan Nees | Method of growing a confluent layer of cells on a porous or semi-permeable substrate and apparatus for practicing the method |
| EP0303294A2 (en) * | 1987-08-14 | 1989-02-15 | Mitsubishi Kasei Corporation | Cell culture filmcarriers |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2761813A (en) * | 1953-01-21 | 1956-09-04 | Goetz Alexander | Means and method of producing and controlling cultures of microorganisms |
| US3839155A (en) * | 1972-07-27 | 1974-10-01 | Merck & Co Inc | Cell and vaccine production |
| US4087327A (en) * | 1976-04-12 | 1978-05-02 | Monsanto Company | Mammalion cell culture process |
| DE2624047C3 (de) * | 1976-05-28 | 1980-07-03 | Dr. Rentschler Arzneimittel Gmbh & Co, 7958 Laupheim | Massenzüchtung von Zellen und Kammer-System zu ihrer Durchführung |
| DE2726313C3 (de) * | 1977-06-10 | 1980-02-07 | Battelle-Institut E.V., 6000 Frankfurt | Verfahren zur in-vitro-Biosynthese von Hormonen, insbesondere von Insulin |
| US4228243A (en) * | 1978-07-13 | 1980-10-14 | Toray Industries, Inc. | Cell culture propagation apparatus |
| US4242459A (en) * | 1978-11-02 | 1980-12-30 | Chick William L | Cell culture device |
| US4446234A (en) * | 1981-10-23 | 1984-05-01 | The United States Of America As Represented By The Department Of Health And Human Services | Vitro cellular interaction with amnion membrane substrate |
| DE3317551A1 (de) * | 1983-05-13 | 1984-11-15 | Stephan Dipl.-Chem. Dr.rer.nat. 8000 München Nees | Perfusionseinrichtung zum "in vitro"-bespuelen verankerungsabhaengiger biologischer zellsysteme |
| US4661458A (en) * | 1983-08-31 | 1987-04-28 | Cell Environmental Systems, Ltd. | Cell culture system |
| US4748124A (en) * | 1984-10-30 | 1988-05-31 | E. I. Du Pont De Nemours And Company | Compartmentalized cell-culture device and method |
| US4656130A (en) * | 1985-03-14 | 1987-04-07 | Yissum Research Development Company | Collagen coated cell growth plates |
| US4681853A (en) * | 1985-10-23 | 1987-07-21 | Hardy Kenneth J | Perfusion slit chamber for filter-bound sample analyses |
| US4661455A (en) * | 1986-01-16 | 1987-04-28 | Dorr-Oliver Incorporated | Membrane cell culturing device |
| US4835102A (en) * | 1987-03-31 | 1989-05-30 | Eugene Bell | Tissue equivalent test systems |
| US4937196A (en) * | 1989-08-18 | 1990-06-26 | Brunswick Corporation | Membrane bioreactor system |
-
1989
- 1989-07-14 DE DE3923279A patent/DE3923279A1/de active Granted
-
1990
- 1990-12-14 US US07/627,729 patent/US5190878A/en not_active Expired - Lifetime
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4608342A (en) * | 1983-05-13 | 1986-08-26 | Stephan Nees | Method of growing a confluent layer of cells on a porous or semi-permeable substrate and apparatus for practicing the method |
| EP0303294A2 (en) * | 1987-08-14 | 1989-02-15 | Mitsubishi Kasei Corporation | Cell culture filmcarriers |
Cited By (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1991018653A3 (en) * | 1990-06-04 | 1994-08-18 | Molecular Devices Corp | Cell assay device |
| WO1992020780A1 (de) * | 1991-05-17 | 1992-11-26 | Uwe Marx | Verfahren und vorrichtung zur gleichzeitigen kultivierung unterschiedlicher säugerzellen |
| US6306644B1 (en) | 1991-05-17 | 2001-10-23 | Uwe Marx | Device for cultivating different mammal cells at the same time |
| DE4305405C1 (de) * | 1993-02-22 | 1994-05-26 | Hering Steffen Dr Sc Med | Vorrichtung zum Untersuchen eines Objekts, das sich in einer ein Substrat bedeckenden Perfusionsflüssigkeit befindet |
| WO1996003094A1 (de) * | 1994-07-25 | 1996-02-08 | W.L. Gore & Associates Gmbh | Membran zur regeneration von körpergeweben und verwendung der membran als wundabdeckung und hautersatz |
| FR2735496A1 (fr) * | 1995-06-15 | 1996-12-20 | Chemodyne Sa | Nouveau dispositif de culture de cellules et les tissus ainsi recoltes |
| WO1997000314A1 (en) * | 1995-06-15 | 1997-01-03 | Chemodyne S.A. | Cell culture device |
| US5958762A (en) * | 1995-06-15 | 1999-09-28 | Chemodyne S.A. | Cell culture device |
| DE19818425A1 (de) * | 1997-10-18 | 1999-07-15 | Malte Dr Med Boehm | Vorrichtung zur Handhabung von Proben für die membrangestützte Mikrodissektion |
| EP0926480A3 (de) * | 1997-10-18 | 2001-08-16 | Malte Dr. Böhm | Vorrichtung zur Handhabung von Proben für die membrangestützte Mikrodissektion |
| FR2801899A1 (fr) * | 1998-08-03 | 2001-06-08 | Acm Biotech Gmbh | Dispositif destine a la culture de cellules |
| NL1013649C2 (nl) * | 1998-08-03 | 2001-05-28 | Andreas Aschenbrenner | Celkweekinrichting. |
| AT407047B (de) * | 1998-08-03 | 2000-11-27 | Pfaller Walter Dr | Zellkulturvorrichtung |
| US6329195B1 (en) | 1998-08-03 | 2001-12-11 | Acm-Biotech Gmbh | Cell culture apparatus |
| WO2005113743A3 (de) * | 2004-05-19 | 2006-06-15 | Univ Rostock | Vorrichtung zur durchführung einer liquid-air-kultur von epithel |
| DE102010023794A1 (de) | 2010-04-09 | 2011-10-13 | Stefan Neumeyer | Medizinisches, insbesondere zahnmedizinisches Substrat |
| WO2012085268A3 (de) * | 2010-12-23 | 2012-08-30 | Universität Rostock | Zellreaktor |
| WO2013117193A1 (de) | 2012-02-09 | 2013-08-15 | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e. V. | Stimulationszelle und verfahren zur in vitro stimulation von zellen oder geweben |
| DE102012101078A1 (de) | 2012-02-09 | 2013-10-17 | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. | Stimulationszelle und Verfahren zur in vitro Stimulation von Zellen oder Geweben |
| WO2015169287A1 (de) * | 2014-05-08 | 2015-11-12 | Universitätsklinikum Jena | Verfahren und vorrichtungen zur in-vitro-herstellung von anordnungen von zellschichten |
| US10731119B2 (en) | 2014-05-08 | 2020-08-04 | Universitaetsklinikum Jena | Method and devices for the in vitro production of arrangements of cell layers |
Also Published As
| Publication number | Publication date |
|---|---|
| US5190878A (en) | 1993-03-02 |
| DE3923279C2 (enExample) | 1991-01-31 |
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