DE3809978A1 - Reservoir fuer gesteuerte wirkstoffabgabe, dieses enthaltende vorrichtung, sowie verfahren zu deren herstellung und verwendung der vorrichtung - Google Patents
Reservoir fuer gesteuerte wirkstoffabgabe, dieses enthaltende vorrichtung, sowie verfahren zu deren herstellung und verwendung der vorrichtungInfo
- Publication number
- DE3809978A1 DE3809978A1 DE3809978A DE3809978A DE3809978A1 DE 3809978 A1 DE3809978 A1 DE 3809978A1 DE 3809978 A DE3809978 A DE 3809978A DE 3809978 A DE3809978 A DE 3809978A DE 3809978 A1 DE3809978 A1 DE 3809978A1
- Authority
- DE
- Germany
- Prior art keywords
- reservoir
- delivery
- cross
- release
- area
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000013543 active substance Substances 0.000 title claims abstract description 19
- 238000004519 manufacturing process Methods 0.000 title claims description 9
- 238000000034 method Methods 0.000 title description 5
- 239000003814 drug Substances 0.000 claims abstract description 17
- 241000607479 Yersinia pestis Species 0.000 claims abstract description 8
- 239000002537 cosmetic Substances 0.000 claims abstract description 6
- 238000005516 engineering process Methods 0.000 claims abstract description 6
- 239000007788 liquid Substances 0.000 claims abstract description 6
- 239000007787 solid Substances 0.000 claims abstract description 5
- 239000000370 acceptor Substances 0.000 claims abstract 2
- 239000004480 active ingredient Substances 0.000 claims description 27
- 230000009467 reduction Effects 0.000 claims description 22
- 239000012876 carrier material Substances 0.000 claims description 12
- 239000010410 layer Substances 0.000 claims description 12
- 230000003247 decreasing effect Effects 0.000 claims description 6
- 239000000126 substance Substances 0.000 claims description 6
- 239000004820 Pressure-sensitive adhesive Substances 0.000 claims description 5
- 239000004744 fabric Substances 0.000 claims description 5
- 230000001225 therapeutic effect Effects 0.000 claims description 4
- 150000001768 cations Chemical class 0.000 claims description 3
- 238000001816 cooling Methods 0.000 claims description 3
- 239000000470 constituent Substances 0.000 claims description 2
- 238000004132 cross linking Methods 0.000 claims description 2
- 239000002270 dispersing agent Substances 0.000 claims description 2
- 238000004049 embossing Methods 0.000 claims description 2
- 238000001704 evaporation Methods 0.000 claims description 2
- 230000008020 evaporation Effects 0.000 claims description 2
- 238000001125 extrusion Methods 0.000 claims description 2
- 238000007731 hot pressing Methods 0.000 claims description 2
- 239000000155 melt Substances 0.000 claims description 2
- 229920000642 polymer Polymers 0.000 claims description 2
- 230000005855 radiation Effects 0.000 claims description 2
- 238000007493 shaping process Methods 0.000 claims description 2
- 239000002904 solvent Substances 0.000 claims description 2
- 238000010030 laminating Methods 0.000 claims 1
- 239000002356 single layer Substances 0.000 claims 1
- 230000003467 diminishing effect Effects 0.000 abstract 2
- 238000012377 drug delivery Methods 0.000 description 13
- 229940079593 drug Drugs 0.000 description 9
- 238000012360 testing method Methods 0.000 description 8
- 239000011159 matrix material Substances 0.000 description 7
- 239000011241 protective layer Substances 0.000 description 7
- 238000013461 design Methods 0.000 description 6
- 229920002584 Polyethylene Glycol 6000 Polymers 0.000 description 5
- 230000004907 flux Effects 0.000 description 5
- 229940093429 polyethylene glycol 6000 Drugs 0.000 description 5
- 230000000694 effects Effects 0.000 description 4
- 238000002474 experimental method Methods 0.000 description 4
- 239000003795 chemical substances by application Substances 0.000 description 3
- 238000002360 preparation method Methods 0.000 description 3
- NNJPGOLRFBJNIW-HNNXBMFYSA-N (-)-demecolcine Chemical compound C1=C(OC)C(=O)C=C2[C@@H](NC)CCC3=CC(OC)=C(OC)C(OC)=C3C2=C1 NNJPGOLRFBJNIW-HNNXBMFYSA-N 0.000 description 2
- 238000009826 distribution Methods 0.000 description 2
- 239000000463 material Substances 0.000 description 2
- 239000000203 mixture Substances 0.000 description 2
- 230000004048 modification Effects 0.000 description 2
- 238000012986 modification Methods 0.000 description 2
- 238000000926 separation method Methods 0.000 description 2
- 238000003756 stirring Methods 0.000 description 2
- 239000000758 substrate Substances 0.000 description 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 2
- FUFLCEKSBBHCMO-UHFFFAOYSA-N 11-dehydrocorticosterone Natural products O=C1CCC2(C)C3C(=O)CC(C)(C(CC4)C(=O)CO)C4C3CCC2=C1 FUFLCEKSBBHCMO-UHFFFAOYSA-N 0.000 description 1
- MFYSYFVPBJMHGN-ZPOLXVRWSA-N Cortisone Chemical compound O=C1CC[C@]2(C)[C@H]3C(=O)C[C@](C)([C@@](CC4)(O)C(=O)CO)[C@@H]4[C@@H]3CCC2=C1 MFYSYFVPBJMHGN-ZPOLXVRWSA-N 0.000 description 1
- MFYSYFVPBJMHGN-UHFFFAOYSA-N Cortisone Natural products O=C1CCC2(C)C3C(=O)CC(C)(C(CC4)(O)C(=O)CO)C4C3CCC2=C1 MFYSYFVPBJMHGN-UHFFFAOYSA-N 0.000 description 1
- 125000002066 L-histidyl group Chemical group [H]N1C([H])=NC(C([H])([H])[C@](C(=O)[*])([H])N([H])[H])=C1[H] 0.000 description 1
- SNIOPGDIGTZGOP-UHFFFAOYSA-N Nitroglycerin Chemical compound [O-][N+](=O)OCC(O[N+]([O-])=O)CO[N+]([O-])=O SNIOPGDIGTZGOP-UHFFFAOYSA-N 0.000 description 1
- 239000000006 Nitroglycerin Substances 0.000 description 1
- 230000009471 action Effects 0.000 description 1
- 230000006978 adaptation Effects 0.000 description 1
- 239000000853 adhesive Substances 0.000 description 1
- 230000001070 adhesive effect Effects 0.000 description 1
- 239000012790 adhesive layer Substances 0.000 description 1
- 238000005452 bending Methods 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 230000008859 change Effects 0.000 description 1
- 230000000052 comparative effect Effects 0.000 description 1
- 238000013270 controlled release Methods 0.000 description 1
- 229960004544 cortisone Drugs 0.000 description 1
- 230000001419 dependent effect Effects 0.000 description 1
- 238000011161 development Methods 0.000 description 1
- 230000018109 developmental process Effects 0.000 description 1
- 230000009189 diving Effects 0.000 description 1
- 238000001035 drying Methods 0.000 description 1
- 230000002500 effect on skin Effects 0.000 description 1
- 239000003623 enhancer Substances 0.000 description 1
- 229960003711 glyceryl trinitrate Drugs 0.000 description 1
- 238000003475 lamination Methods 0.000 description 1
- 239000004816 latex Substances 0.000 description 1
- 229920000126 latex Polymers 0.000 description 1
- 239000002674 ointment Substances 0.000 description 1
- 230000003287 optical effect Effects 0.000 description 1
- 210000000056 organ Anatomy 0.000 description 1
- 238000004513 sizing Methods 0.000 description 1
- 239000011343 solid material Substances 0.000 description 1
- 238000007711 solidification Methods 0.000 description 1
- 230000008023 solidification Effects 0.000 description 1
- 238000005507 spraying Methods 0.000 description 1
- 239000006228 supernatant Substances 0.000 description 1
- 239000013595 supernatant sample Substances 0.000 description 1
- 238000012549 training Methods 0.000 description 1
- 230000007704 transition Effects 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M35/00—Devices for applying media, e.g. remedies, on the human body
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
- A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
- A61K9/7084—Transdermal patches having a drug layer or reservoir, and one or more separate drug-free skin-adhesive layers, e.g. between drug reservoir and skin, or surrounding the drug reservoir; Liquid-filled reservoir patches
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
- A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
- A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
- A61K9/7092—Transdermal patches having multiple drug layers or reservoirs, e.g. for obtaining a specific release pattern, or for combining different drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F13/00—Bandages or dressings; Absorbent pads
- A61F13/02—Adhesive bandages or dressings
- A61F13/0276—Apparatus or processes for manufacturing adhesive dressings or bandages
- A61F2013/0296—Apparatus or processes for manufacturing adhesive dressings or bandages for making transdermal patches (chemical processes excluded)
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Dermatology (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Chemical & Material Sciences (AREA)
- Hematology (AREA)
- Heart & Thoracic Surgery (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Medicinal Preparation (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Lubricants (AREA)
- Medicines Containing Plant Substances (AREA)
- Catching Or Destruction (AREA)
- Media Introduction/Drainage Providing Device (AREA)
- Detergent Compositions (AREA)
- Stabilization Of Oscillater, Synchronisation, Frequency Synthesizers (AREA)
- Oscillators With Electromechanical Resonators (AREA)
- Battery Electrode And Active Subsutance (AREA)
- Bidet-Like Cleaning Device And Other Flush Toilet Accessories (AREA)
- Steroid Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Nozzles (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
- Seasonings (AREA)
Priority Applications (27)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE3809978A DE3809978A1 (de) | 1988-03-24 | 1988-03-24 | Reservoir fuer gesteuerte wirkstoffabgabe, dieses enthaltende vorrichtung, sowie verfahren zu deren herstellung und verwendung der vorrichtung |
| IL89603A IL89603A (en) | 1988-03-24 | 1989-03-14 | Reservoir for controlled active substance delivery, apparatus containing the same and method for the manufacture and use of the apparatus |
| MYPI89000315A MY110263A (en) | 1988-03-24 | 1989-03-15 | Reservoir for controlled active substance delivery, apparatus containing the same, as well as method for its manufacture and use of the apparatus. |
| ZA891949A ZA891949B (en) | 1988-03-24 | 1989-03-15 | Reservoir for controlled active substance delivery,apparatus containing the same,as well as method for its manufacture and use of the apparatus |
| CA000593795A CA1336665C (en) | 1988-03-24 | 1989-03-15 | Reservoir for controlled active substance delivery, apparatus containing the same, as well as method for its manufacture and use of the apparatus |
| KR1019890702080A KR0145310B1 (ko) | 1988-03-24 | 1989-03-21 | 유효성분방출조절용 저장소, 이를 포함한 장치, 및 그 제조방법 |
| DE58909724T DE58909724D1 (de) | 1988-03-24 | 1989-03-21 | Verwendung einer Vorrichtung mit einem Wirkstoffreservoir für gesteuerte Wirkstoffabgabe |
| HU892315A HU210618B (en) | 1988-03-24 | 1989-03-21 | Container and construction with feeding surface providing continously decreasing feed for solid, liquid or gaseous mediums, as well as method for producing shid construction |
| ES89105078T ES2103702T3 (es) | 1988-03-24 | 1989-03-21 | Empleo de un dispositivo provisto de un deposito que contiene sustancia activa para la cesion controlada de la sustancia activa. |
| AT89105078T ATE142517T1 (de) | 1988-03-24 | 1989-03-21 | Verwendung einer vorrichtung mit einem wirkstoffreservoir für gesteuerte wirkstoffabgabe |
| EP89105078A EP0334306B1 (de) | 1988-03-24 | 1989-03-21 | Verwendung einer Vorrichtung mit einem Wirkstoffreservoir für gesteuerte Wirkstoffabgabe |
| JP50318089A JP3154478B2 (ja) | 1988-03-24 | 1989-03-21 | 制御された活性物質を供給するためのリザーバー、該物質を収容する装置、及び該装置を製造し使用する方法 |
| PCT/DE1989/000177 WO1989009080A1 (fr) | 1988-03-24 | 1989-03-21 | Reservoir pour diffusion regulee de substances actives, dispositif le contenant, procede pour la fabrication du dispositif et utilisation de ce dernier |
| PT90058A PT90058B (pt) | 1988-03-24 | 1989-03-21 | Reservatorio com uma superficie de libertacao para a libertacao controlada de substancias activas, aparelho contendo o mesmo, e processo para o seu fabrico |
| AU32173/89A AU639664B2 (en) | 1988-03-24 | 1989-03-21 | Reservoir for controlled release of active substances, device containing it, process for producing it, and use of the device |
| DD89326809A DD283567A5 (de) | 1988-03-24 | 1989-03-22 | Reservoir fuer gesteuerte wirkstoffabgabe, sowie verfahren zur herstellung einer dieses enthaltenden vorrichtung und verwendung der vorrichtung |
| NZ228455A NZ228455A (en) | 1988-03-24 | 1989-03-22 | Controlled active-substance delivery article, manufacture and use |
| IE90889A IE80803B1 (en) | 1988-03-24 | 1989-03-23 | Reservoir for controlled active substance delivery apparatus containing the same as well as method for its manufacture and use of the apparatus |
| CS891812A CZ281559B6 (cs) | 1988-03-24 | 1989-03-23 | Zásobník pro řízené předávání účinné látky, zařízení obsahující takový zásobník a způsob jeho výroby a použití |
| PL89278443A PL162187B1 (en) | 1988-03-24 | 1989-03-23 | Container for controlled evolution of active substances, device with container for evolving active substances and a method for manufacturing the device with container for controlled evolution of active substances |
| SK1812-89A SK279081B6 (sk) | 1988-03-24 | 1989-03-23 | Zariadenie s odovzdávacou plochou a spôsob jeho vý |
| YU00600/89A YU60089A (en) | 1988-03-24 | 1989-03-24 | Reservoir for controlled releasing of active material |
| NO894467A NO174536C (no) | 1988-03-24 | 1989-11-09 | Innretning for styring over anvendelsestiden avtagende avgivelse av aktive stoffer til en akseptant |
| DK594889A DK171223B1 (da) | 1988-03-24 | 1989-11-24 | Indretning til styret i løbet af anvendelsestiden aftagende afgivelse af stoffer |
| FI895638A FI104151B1 (fi) | 1988-03-24 | 1989-11-24 | Laite vaikuttavan aineen luovuttamiseksi ohjatusti |
| US08/521,954 US6207181B1 (en) | 1988-03-24 | 1995-08-31 | Reservoir for controlled active substance delivery, and apparatus containing the same |
| GR960402963T GR3021589T3 (en) | 1988-03-24 | 1996-11-07 | Use of a device having a reservoir containing an active substance for the controlled release of the active substance |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE3809978A DE3809978A1 (de) | 1988-03-24 | 1988-03-24 | Reservoir fuer gesteuerte wirkstoffabgabe, dieses enthaltende vorrichtung, sowie verfahren zu deren herstellung und verwendung der vorrichtung |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE3809978A1 true DE3809978A1 (de) | 1989-10-05 |
| DE3809978C2 DE3809978C2 (enExample) | 1992-03-12 |
Family
ID=6350601
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE3809978A Granted DE3809978A1 (de) | 1988-03-24 | 1988-03-24 | Reservoir fuer gesteuerte wirkstoffabgabe, dieses enthaltende vorrichtung, sowie verfahren zu deren herstellung und verwendung der vorrichtung |
| DE58909724T Expired - Fee Related DE58909724D1 (de) | 1988-03-24 | 1989-03-21 | Verwendung einer Vorrichtung mit einem Wirkstoffreservoir für gesteuerte Wirkstoffabgabe |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE58909724T Expired - Fee Related DE58909724D1 (de) | 1988-03-24 | 1989-03-21 | Verwendung einer Vorrichtung mit einem Wirkstoffreservoir für gesteuerte Wirkstoffabgabe |
Country Status (25)
| Country | Link |
|---|---|
| US (1) | US6207181B1 (enExample) |
| EP (1) | EP0334306B1 (enExample) |
| JP (1) | JP3154478B2 (enExample) |
| KR (1) | KR0145310B1 (enExample) |
| AT (1) | ATE142517T1 (enExample) |
| AU (1) | AU639664B2 (enExample) |
| CA (1) | CA1336665C (enExample) |
| CZ (1) | CZ281559B6 (enExample) |
| DD (1) | DD283567A5 (enExample) |
| DE (2) | DE3809978A1 (enExample) |
| ES (1) | ES2103702T3 (enExample) |
| FI (1) | FI104151B1 (enExample) |
| GR (1) | GR3021589T3 (enExample) |
| HU (1) | HU210618B (enExample) |
| IE (1) | IE80803B1 (enExample) |
| IL (1) | IL89603A (enExample) |
| MY (1) | MY110263A (enExample) |
| NO (1) | NO174536C (enExample) |
| NZ (1) | NZ228455A (enExample) |
| PL (1) | PL162187B1 (enExample) |
| PT (1) | PT90058B (enExample) |
| SK (1) | SK279081B6 (enExample) |
| WO (1) | WO1989009080A1 (enExample) |
| YU (1) | YU60089A (enExample) |
| ZA (1) | ZA891949B (enExample) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5853760A (en) * | 1993-12-04 | 1998-12-29 | Lts Lohmann Therapie-Systeme Gmbh & Co. Kg | Device for the controlled release of active substances |
| US6756052B1 (en) | 1999-05-21 | 2004-06-29 | Lts Lohmann Therapie-Systeme Ag | Device and method for increasing the transdermal permeation of medicaments |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3908432A1 (de) * | 1989-03-14 | 1990-09-27 | Lohmann Therapie Syst Lts | Pflaster als therapeutisches system zur verabreichung von wirkstoffen an die haut mit einer abgestuften wirkstoffabgabe, verfahren zu seiner herstellung sowie verwendung |
| US6002797A (en) | 1994-06-22 | 1999-12-14 | Hitachi, Ltd. | Apparatus for detecting position of featuring region of picture, such as subtitle or imageless part |
| DE19820999A1 (de) * | 1998-05-11 | 1999-11-18 | Lohmann Therapie Syst Lts | Laminat zum Aufbringen auf einen Akzeptor |
| SI1294356T1 (sl) * | 2000-03-21 | 2007-12-31 | Farrington Pharmaceuticals Llc | Sproĺ äśujoäś nepretrgan razdeljevalni sistem za raztopljene snovi |
| US6569152B2 (en) | 2000-03-21 | 2003-05-27 | Farrington Pharmaceuticals, Llc | Sustained release delivery systems for solutes |
| SE0101154D0 (sv) * | 2001-03-29 | 2001-03-29 | St Jude Medical | An electrically conductive lead and a method of producing such a lead |
| US6893655B2 (en) * | 2001-10-09 | 2005-05-17 | 3M Innovative Properties Co. | Transdermal delivery devices |
| DE10250848A1 (de) * | 2002-10-24 | 2004-05-13 | Paul Hartmann Ag | Wundkontaktmaterial |
| EP2018835B1 (de) * | 2007-07-09 | 2014-03-05 | Augustinus Bader | Wirkstoff abgebendes Pflaster |
| EP3829505A1 (en) * | 2018-07-30 | 2021-06-09 | 3M Innovative Properties Company | Antimicrobial foam articles and method of making the same |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0227252A2 (en) * | 1985-10-30 | 1987-07-01 | Alza Corporation | Medical device for pulsatile transdermal delivery of biologically active agents |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4690683A (en) * | 1985-07-02 | 1987-09-01 | Rutgers, The State University Of New Jersey | Transdermal varapamil delivery device |
| DE3634016A1 (de) * | 1986-04-17 | 1987-10-29 | Lohmann Gmbh & Co Kg | Flaechenfoermiges therapeutisches system, verfahren zu seiner herstellung und seine verwendung |
| US4816262A (en) * | 1986-08-28 | 1989-03-28 | Universite De Montreal | Controlled release tablet |
| US4803076A (en) * | 1986-09-04 | 1989-02-07 | Pfizer Inc. | Controlled release device for an active substance |
| US4849224A (en) * | 1987-11-12 | 1989-07-18 | Theratech Inc. | Device for administering an active agent to the skin or mucosa |
-
1988
- 1988-03-24 DE DE3809978A patent/DE3809978A1/de active Granted
-
1989
- 1989-03-14 IL IL89603A patent/IL89603A/xx not_active IP Right Cessation
- 1989-03-15 ZA ZA891949A patent/ZA891949B/xx unknown
- 1989-03-15 MY MYPI89000315A patent/MY110263A/en unknown
- 1989-03-15 CA CA000593795A patent/CA1336665C/en not_active Expired - Fee Related
- 1989-03-21 EP EP89105078A patent/EP0334306B1/de not_active Expired - Lifetime
- 1989-03-21 DE DE58909724T patent/DE58909724D1/de not_active Expired - Fee Related
- 1989-03-21 PT PT90058A patent/PT90058B/pt not_active IP Right Cessation
- 1989-03-21 JP JP50318089A patent/JP3154478B2/ja not_active Expired - Fee Related
- 1989-03-21 HU HU892315A patent/HU210618B/hu not_active IP Right Cessation
- 1989-03-21 AU AU32173/89A patent/AU639664B2/en not_active Ceased
- 1989-03-21 KR KR1019890702080A patent/KR0145310B1/ko not_active Expired - Fee Related
- 1989-03-21 ES ES89105078T patent/ES2103702T3/es not_active Expired - Lifetime
- 1989-03-21 WO PCT/DE1989/000177 patent/WO1989009080A1/de not_active Ceased
- 1989-03-21 AT AT89105078T patent/ATE142517T1/de not_active IP Right Cessation
- 1989-03-22 DD DD89326809A patent/DD283567A5/de not_active IP Right Cessation
- 1989-03-22 NZ NZ228455A patent/NZ228455A/xx unknown
- 1989-03-23 CZ CS891812A patent/CZ281559B6/cs unknown
- 1989-03-23 PL PL89278443A patent/PL162187B1/pl unknown
- 1989-03-23 IE IE90889A patent/IE80803B1/en not_active IP Right Cessation
- 1989-03-23 SK SK1812-89A patent/SK279081B6/sk unknown
- 1989-03-24 YU YU00600/89A patent/YU60089A/xx unknown
- 1989-11-09 NO NO894467A patent/NO174536C/no not_active IP Right Cessation
- 1989-11-24 FI FI895638A patent/FI104151B1/fi not_active IP Right Cessation
-
1995
- 1995-08-31 US US08/521,954 patent/US6207181B1/en not_active Expired - Fee Related
-
1996
- 1996-11-07 GR GR960402963T patent/GR3021589T3/el unknown
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0227252A2 (en) * | 1985-10-30 | 1987-07-01 | Alza Corporation | Medical device for pulsatile transdermal delivery of biologically active agents |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5853760A (en) * | 1993-12-04 | 1998-12-29 | Lts Lohmann Therapie-Systeme Gmbh & Co. Kg | Device for the controlled release of active substances |
| US6756052B1 (en) | 1999-05-21 | 2004-06-29 | Lts Lohmann Therapie-Systeme Ag | Device and method for increasing the transdermal permeation of medicaments |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| OP8 | Request for examination as to paragraph 44 patent law | ||
| 8127 | New person/name/address of the applicant |
Owner name: LTS LOHMANN THERAPIE-SYSTEME GMBH & CO KG, 5450 NE |
|
| D2 | Grant after examination | ||
| 8364 | No opposition during term of opposition | ||
| 8339 | Ceased/non-payment of the annual fee |