JP3154478B2 - 制御された活性物質を供給するためのリザーバー、該物質を収容する装置、及び該装置を製造し使用する方法 - Google Patents
制御された活性物質を供給するためのリザーバー、該物質を収容する装置、及び該装置を製造し使用する方法Info
- Publication number
- JP3154478B2 JP3154478B2 JP50318089A JP50318089A JP3154478B2 JP 3154478 B2 JP3154478 B2 JP 3154478B2 JP 50318089 A JP50318089 A JP 50318089A JP 50318089 A JP50318089 A JP 50318089A JP 3154478 B2 JP3154478 B2 JP 3154478B2
- Authority
- JP
- Japan
- Prior art keywords
- reservoir
- active substance
- supply
- cross
- supply surface
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 239000013543 active substance Substances 0.000 title claims abstract description 73
- 238000004519 manufacturing process Methods 0.000 title claims description 10
- 239000000126 substance Substances 0.000 title description 8
- 239000003814 drug Substances 0.000 claims abstract description 8
- 239000007788 liquid Substances 0.000 claims abstract description 8
- 239000007787 solid Substances 0.000 claims abstract description 7
- 239000002537 cosmetic Substances 0.000 claims abstract description 5
- 239000000463 material Substances 0.000 claims description 25
- 230000009467 reduction Effects 0.000 claims description 24
- 230000007423 decrease Effects 0.000 claims description 13
- 238000000034 method Methods 0.000 claims description 8
- 239000004821 Contact adhesive Substances 0.000 claims description 7
- 230000001603 reducing effect Effects 0.000 claims description 5
- 238000001816 cooling Methods 0.000 claims description 3
- 230000003247 decreasing effect Effects 0.000 claims description 3
- 229920000642 polymer Polymers 0.000 claims description 3
- 238000007598 dipping method Methods 0.000 claims description 2
- 239000002270 dispersing agent Substances 0.000 claims description 2
- 230000005855 radiation Effects 0.000 claims description 2
- 238000005507 spraying Methods 0.000 claims description 2
- 230000006835 compression Effects 0.000 claims 1
- 238000007906 compression Methods 0.000 claims 1
- 238000004132 cross linking Methods 0.000 claims 1
- 238000001704 evaporation Methods 0.000 claims 1
- 238000001125 extrusion Methods 0.000 claims 1
- 238000000465 moulding Methods 0.000 claims 1
- 239000000575 pesticide Substances 0.000 claims 1
- 241000607479 Yersinia pestis Species 0.000 abstract description 5
- 238000005516 engineering process Methods 0.000 abstract description 3
- 230000003467 diminishing effect Effects 0.000 abstract 2
- 239000000370 acceptor Substances 0.000 abstract 1
- 238000012360 testing method Methods 0.000 description 14
- 238000009833 condensation Methods 0.000 description 9
- 230000005494 condensation Effects 0.000 description 9
- 239000010410 layer Substances 0.000 description 9
- 239000011159 matrix material Substances 0.000 description 8
- 238000013461 design Methods 0.000 description 7
- 239000000243 solution Substances 0.000 description 4
- 229920002584 Polyethylene Glycol 6000 Polymers 0.000 description 3
- 239000011241 protective layer Substances 0.000 description 3
- 239000008118 PEG 6000 Substances 0.000 description 2
- 230000008859 change Effects 0.000 description 2
- MTHSVFCYNBDYFN-UHFFFAOYSA-N diethylene glycol Chemical compound OCCOCCO MTHSVFCYNBDYFN-UHFFFAOYSA-N 0.000 description 2
- 238000009826 distribution Methods 0.000 description 2
- 238000010438 heat treatment Methods 0.000 description 2
- 239000000203 mixture Substances 0.000 description 2
- 229940093429 polyethylene glycol 6000 Drugs 0.000 description 2
- 238000002360 preparation method Methods 0.000 description 2
- 238000000926 separation method Methods 0.000 description 2
- 238000003756 stirring Methods 0.000 description 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 2
- FUFLCEKSBBHCMO-UHFFFAOYSA-N 11-dehydrocorticosterone Natural products O=C1CCC2(C)C3C(=O)CC(C)(C(CC4)C(=O)CO)C4C3CCC2=C1 FUFLCEKSBBHCMO-UHFFFAOYSA-N 0.000 description 1
- MFYSYFVPBJMHGN-ZPOLXVRWSA-N Cortisone Chemical compound O=C1CC[C@]2(C)[C@H]3C(=O)C[C@](C)([C@@](CC4)(O)C(=O)CO)[C@@H]4[C@@H]3CCC2=C1 MFYSYFVPBJMHGN-ZPOLXVRWSA-N 0.000 description 1
- MFYSYFVPBJMHGN-UHFFFAOYSA-N Cortisone Natural products O=C1CCC2(C)C3C(=O)CC(C)(C(CC4)(O)C(=O)CO)C4C3CCC2=C1 MFYSYFVPBJMHGN-UHFFFAOYSA-N 0.000 description 1
- 241001465754 Metazoa Species 0.000 description 1
- SNIOPGDIGTZGOP-UHFFFAOYSA-N Nitroglycerin Chemical compound [O-][N+](=O)OCC(O[N+]([O-])=O)CO[N+]([O-])=O SNIOPGDIGTZGOP-UHFFFAOYSA-N 0.000 description 1
- 239000000006 Nitroglycerin Substances 0.000 description 1
- 239000004698 Polyethylene Substances 0.000 description 1
- 230000009471 action Effects 0.000 description 1
- 230000004913 activation Effects 0.000 description 1
- 239000000853 adhesive Substances 0.000 description 1
- 230000001070 adhesive effect Effects 0.000 description 1
- 239000012790 adhesive layer Substances 0.000 description 1
- 230000004071 biological effect Effects 0.000 description 1
- 230000005540 biological transmission Effects 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- 239000011248 coating agent Substances 0.000 description 1
- 238000000576 coating method Methods 0.000 description 1
- 230000000052 comparative effect Effects 0.000 description 1
- 238000007796 conventional method Methods 0.000 description 1
- 229960004544 cortisone Drugs 0.000 description 1
- 239000008367 deionised water Substances 0.000 description 1
- 229910021641 deionized water Inorganic materials 0.000 description 1
- 230000001419 dependent effect Effects 0.000 description 1
- 238000011161 development Methods 0.000 description 1
- 230000018109 developmental process Effects 0.000 description 1
- 238000010790 dilution Methods 0.000 description 1
- 239000012895 dilution Substances 0.000 description 1
- 238000007599 discharging Methods 0.000 description 1
- 239000002552 dosage form Substances 0.000 description 1
- 239000003623 enhancer Substances 0.000 description 1
- 238000009415 formwork Methods 0.000 description 1
- 229960003711 glyceryl trinitrate Drugs 0.000 description 1
- 238000003475 lamination Methods 0.000 description 1
- 239000002674 ointment Substances 0.000 description 1
- 230000003287 optical effect Effects 0.000 description 1
- 239000011505 plaster Substances 0.000 description 1
- 238000004080 punching Methods 0.000 description 1
- 230000004044 response Effects 0.000 description 1
- 229920006395 saturated elastomer Polymers 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M35/00—Devices for applying media, e.g. remedies, on the human body
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
- A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
- A61K9/7084—Transdermal patches having a drug layer or reservoir, and one or more separate drug-free skin-adhesive layers, e.g. between drug reservoir and skin, or surrounding the drug reservoir; Liquid-filled reservoir patches
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
- A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
- A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
- A61K9/7092—Transdermal patches having multiple drug layers or reservoirs, e.g. for obtaining a specific release pattern, or for combining different drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F13/00—Bandages or dressings; Absorbent pads
- A61F13/02—Adhesive bandages or dressings
- A61F13/0276—Apparatus or processes for manufacturing adhesive dressings or bandages
- A61F2013/0296—Apparatus or processes for manufacturing adhesive dressings or bandages for making transdermal patches (chemical processes excluded)
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Dermatology (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Chemical & Material Sciences (AREA)
- Hematology (AREA)
- Heart & Thoracic Surgery (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Medicinal Preparation (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Lubricants (AREA)
- Medicines Containing Plant Substances (AREA)
- Catching Or Destruction (AREA)
- Detergent Compositions (AREA)
- Media Introduction/Drainage Providing Device (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Steroid Compounds (AREA)
- Bidet-Like Cleaning Device And Other Flush Toilet Accessories (AREA)
- Battery Electrode And Active Subsutance (AREA)
- Nozzles (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
- Seasonings (AREA)
- Stabilization Of Oscillater, Synchronisation, Frequency Synthesizers (AREA)
- Oscillators With Electromechanical Resonators (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE3809978A DE3809978A1 (de) | 1988-03-24 | 1988-03-24 | Reservoir fuer gesteuerte wirkstoffabgabe, dieses enthaltende vorrichtung, sowie verfahren zu deren herstellung und verwendung der vorrichtung |
| DE3809978.0 | 1988-03-24 | ||
| PCT/DE1989/000177 WO1989009080A1 (fr) | 1988-03-24 | 1989-03-21 | Reservoir pour diffusion regulee de substances actives, dispositif le contenant, procede pour la fabrication du dispositif et utilisation de ce dernier |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPH02503524A JPH02503524A (ja) | 1990-10-25 |
| JP3154478B2 true JP3154478B2 (ja) | 2001-04-09 |
Family
ID=6350601
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP50318089A Expired - Fee Related JP3154478B2 (ja) | 1988-03-24 | 1989-03-21 | 制御された活性物質を供給するためのリザーバー、該物質を収容する装置、及び該装置を製造し使用する方法 |
Country Status (25)
| Country | Link |
|---|---|
| US (1) | US6207181B1 (enExample) |
| EP (1) | EP0334306B1 (enExample) |
| JP (1) | JP3154478B2 (enExample) |
| KR (1) | KR0145310B1 (enExample) |
| AT (1) | ATE142517T1 (enExample) |
| AU (1) | AU639664B2 (enExample) |
| CA (1) | CA1336665C (enExample) |
| CZ (1) | CZ281559B6 (enExample) |
| DD (1) | DD283567A5 (enExample) |
| DE (2) | DE3809978A1 (enExample) |
| ES (1) | ES2103702T3 (enExample) |
| FI (1) | FI104151B1 (enExample) |
| GR (1) | GR3021589T3 (enExample) |
| HU (1) | HU210618B (enExample) |
| IE (1) | IE80803B1 (enExample) |
| IL (1) | IL89603A (enExample) |
| MY (1) | MY110263A (enExample) |
| NO (1) | NO174536C (enExample) |
| NZ (1) | NZ228455A (enExample) |
| PL (1) | PL162187B1 (enExample) |
| PT (1) | PT90058B (enExample) |
| SK (1) | SK279081B6 (enExample) |
| WO (1) | WO1989009080A1 (enExample) |
| YU (1) | YU60089A (enExample) |
| ZA (1) | ZA891949B (enExample) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6621927B1 (en) | 1994-06-22 | 2003-09-16 | Hitachi, Ltd. | Apparatus for detecting position of featuring region of picture, such as subtitle or imageless part |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3908432A1 (de) * | 1989-03-14 | 1990-09-27 | Lohmann Therapie Syst Lts | Pflaster als therapeutisches system zur verabreichung von wirkstoffen an die haut mit einer abgestuften wirkstoffabgabe, verfahren zu seiner herstellung sowie verwendung |
| DE4341442C2 (de) * | 1993-12-04 | 1998-11-05 | Lohmann Therapie Syst Lts | Vorrichtung zur kontrollierten Freisetzung von Wirkstoffen sowie ihre Verwendung |
| DE19820999A1 (de) * | 1998-05-11 | 1999-11-18 | Lohmann Therapie Syst Lts | Laminat zum Aufbringen auf einen Akzeptor |
| DE19923427A1 (de) | 1999-05-21 | 2000-11-23 | Lohmann Therapie Syst Lts | Vorrichtung und Verfahren zur Steigerung der transdermalen Permeation von Arzneistoffen |
| US6569152B2 (en) | 2000-03-21 | 2003-05-27 | Farrington Pharmaceuticals, Llc | Sustained release delivery systems for solutes |
| BR0109495A (pt) * | 2000-03-21 | 2004-12-07 | Farrington Pharmaceuticals Llc | Sistemas de transferência de liberação contìnua para solutos |
| SE0101154D0 (sv) * | 2001-03-29 | 2001-03-29 | St Jude Medical | An electrically conductive lead and a method of producing such a lead |
| US6893655B2 (en) * | 2001-10-09 | 2005-05-17 | 3M Innovative Properties Co. | Transdermal delivery devices |
| DE10250848A1 (de) * | 2002-10-24 | 2004-05-13 | Paul Hartmann Ag | Wundkontaktmaterial |
| EP2018835B1 (de) * | 2007-07-09 | 2014-03-05 | Augustinus Bader | Wirkstoff abgebendes Pflaster |
| EP3829505A1 (en) * | 2018-07-30 | 2021-06-09 | 3M Innovative Properties Company | Antimicrobial foam articles and method of making the same |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4690683A (en) * | 1985-07-02 | 1987-09-01 | Rutgers, The State University Of New Jersey | Transdermal varapamil delivery device |
| US4698062A (en) * | 1985-10-30 | 1987-10-06 | Alza Corporation | Medical device for pulsatile transdermal delivery of biologically active agents |
| DE3634016A1 (de) * | 1986-04-17 | 1987-10-29 | Lohmann Gmbh & Co Kg | Flaechenfoermiges therapeutisches system, verfahren zu seiner herstellung und seine verwendung |
| US4816262A (en) * | 1986-08-28 | 1989-03-28 | Universite De Montreal | Controlled release tablet |
| US4803076A (en) * | 1986-09-04 | 1989-02-07 | Pfizer Inc. | Controlled release device for an active substance |
| US4849224A (en) * | 1987-11-12 | 1989-07-18 | Theratech Inc. | Device for administering an active agent to the skin or mucosa |
-
1988
- 1988-03-24 DE DE3809978A patent/DE3809978A1/de active Granted
-
1989
- 1989-03-14 IL IL89603A patent/IL89603A/xx not_active IP Right Cessation
- 1989-03-15 MY MYPI89000315A patent/MY110263A/en unknown
- 1989-03-15 CA CA000593795A patent/CA1336665C/en not_active Expired - Fee Related
- 1989-03-15 ZA ZA891949A patent/ZA891949B/xx unknown
- 1989-03-21 JP JP50318089A patent/JP3154478B2/ja not_active Expired - Fee Related
- 1989-03-21 AT AT89105078T patent/ATE142517T1/de not_active IP Right Cessation
- 1989-03-21 PT PT90058A patent/PT90058B/pt not_active IP Right Cessation
- 1989-03-21 DE DE58909724T patent/DE58909724D1/de not_active Expired - Fee Related
- 1989-03-21 AU AU32173/89A patent/AU639664B2/en not_active Ceased
- 1989-03-21 KR KR1019890702080A patent/KR0145310B1/ko not_active Expired - Fee Related
- 1989-03-21 HU HU892315A patent/HU210618B/hu not_active IP Right Cessation
- 1989-03-21 ES ES89105078T patent/ES2103702T3/es not_active Expired - Lifetime
- 1989-03-21 EP EP89105078A patent/EP0334306B1/de not_active Expired - Lifetime
- 1989-03-21 WO PCT/DE1989/000177 patent/WO1989009080A1/de not_active Ceased
- 1989-03-22 DD DD89326809A patent/DD283567A5/de not_active IP Right Cessation
- 1989-03-22 NZ NZ228455A patent/NZ228455A/xx unknown
- 1989-03-23 IE IE90889A patent/IE80803B1/en not_active IP Right Cessation
- 1989-03-23 SK SK1812-89A patent/SK279081B6/sk unknown
- 1989-03-23 CZ CS891812A patent/CZ281559B6/cs unknown
- 1989-03-23 PL PL89278443A patent/PL162187B1/pl unknown
- 1989-03-24 YU YU00600/89A patent/YU60089A/xx unknown
- 1989-11-09 NO NO894467A patent/NO174536C/no not_active IP Right Cessation
- 1989-11-24 FI FI895638A patent/FI104151B1/fi not_active IP Right Cessation
-
1995
- 1995-08-31 US US08/521,954 patent/US6207181B1/en not_active Expired - Fee Related
-
1996
- 1996-11-07 GR GR960402963T patent/GR3021589T3/el unknown
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6621927B1 (en) | 1994-06-22 | 2003-09-16 | Hitachi, Ltd. | Apparatus for detecting position of featuring region of picture, such as subtitle or imageless part |
Also Published As
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| LAPS | Cancellation because of no payment of annual fees |