DE3738467C2 - - Google Patents
Info
- Publication number
- DE3738467C2 DE3738467C2 DE3738467A DE3738467A DE3738467C2 DE 3738467 C2 DE3738467 C2 DE 3738467C2 DE 3738467 A DE3738467 A DE 3738467A DE 3738467 A DE3738467 A DE 3738467A DE 3738467 C2 DE3738467 C2 DE 3738467C2
- Authority
- DE
- Germany
- Prior art keywords
- separation column
- liquid
- sample
- solution
- elution solution
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 239000007788 liquid Substances 0.000 claims description 74
- 239000000523 sample Substances 0.000 claims description 56
- 238000000926 separation method Methods 0.000 claims description 53
- 238000010828 elution Methods 0.000 claims description 44
- 238000000605 extraction Methods 0.000 claims description 31
- 239000000203 mixture Substances 0.000 claims description 25
- 150000001450 anions Chemical class 0.000 claims description 19
- 238000000034 method Methods 0.000 claims description 12
- 150000002500 ions Chemical class 0.000 claims description 11
- 238000004811 liquid chromatography Methods 0.000 claims description 11
- 230000014759 maintenance of location Effects 0.000 claims description 8
- 238000002156 mixing Methods 0.000 claims description 8
- 238000009826 distribution Methods 0.000 claims description 6
- 239000012488 sample solution Substances 0.000 claims description 6
- 239000000126 substance Substances 0.000 claims description 6
- 238000001514 detection method Methods 0.000 claims description 4
- 230000002378 acidificating effect Effects 0.000 claims description 2
- 229910001854 alkali hydroxide Inorganic materials 0.000 claims description 2
- 150000008044 alkali metal hydroxides Chemical class 0.000 claims description 2
- 230000007935 neutral effect Effects 0.000 claims description 2
- 238000012544 monitoring process Methods 0.000 claims 1
- 239000000243 solution Substances 0.000 description 52
- KWYUFKZDYYNOTN-UHFFFAOYSA-M Potassium hydroxide Chemical compound [OH-].[K+] KWYUFKZDYYNOTN-UHFFFAOYSA-M 0.000 description 15
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 12
- -1 Hydroxyl ions Chemical class 0.000 description 10
- 238000005259 measurement Methods 0.000 description 10
- 238000001179 sorption measurement Methods 0.000 description 8
- 238000002347 injection Methods 0.000 description 7
- 239000007924 injection Substances 0.000 description 7
- 238000005342 ion exchange Methods 0.000 description 7
- NWUYHJFMYQTDRP-UHFFFAOYSA-N 1,2-bis(ethenyl)benzene;1-ethenyl-2-ethylbenzene;styrene Chemical compound C=CC1=CC=CC=C1.CCC1=CC=CC=C1C=C.C=CC1=CC=CC=C1C=C NWUYHJFMYQTDRP-UHFFFAOYSA-N 0.000 description 6
- HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 description 6
- IWZKICVEHNUQTL-UHFFFAOYSA-M potassium hydrogen phthalate Chemical compound [K+].OC(=O)C1=CC=CC=C1C([O-])=O IWZKICVEHNUQTL-UHFFFAOYSA-M 0.000 description 6
- 239000003456 ion exchange resin Substances 0.000 description 5
- 229920003303 ion-exchange polymer Polymers 0.000 description 5
- 238000011067 equilibration Methods 0.000 description 4
- 230000003247 decreasing effect Effects 0.000 description 3
- 230000035945 sensitivity Effects 0.000 description 3
- 239000002250 absorbent Substances 0.000 description 2
- 230000002745 absorbent Effects 0.000 description 2
- 239000012670 alkaline solution Substances 0.000 description 2
- 239000003957 anion exchange resin Substances 0.000 description 2
- 239000007864 aqueous solution Substances 0.000 description 2
- 238000011088 calibration curve Methods 0.000 description 2
- 239000012530 fluid Substances 0.000 description 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-M hydroxide Chemical compound [OH-] XLYOFNOQVPJJNP-UHFFFAOYSA-M 0.000 description 2
- 238000004255 ion exchange chromatography Methods 0.000 description 2
- 239000000463 material Substances 0.000 description 2
- 238000012856 packing Methods 0.000 description 2
- 239000002904 solvent Substances 0.000 description 2
- 239000012498 ultrapure water Substances 0.000 description 2
- VHUUQVKOLVNVRT-UHFFFAOYSA-N Ammonium hydroxide Chemical compound [NH4+].[OH-] VHUUQVKOLVNVRT-UHFFFAOYSA-N 0.000 description 1
- CPELXLSAUQHCOX-UHFFFAOYSA-M Bromide Chemical compound [Br-] CPELXLSAUQHCOX-UHFFFAOYSA-M 0.000 description 1
- VEXZGXHMUGYJMC-UHFFFAOYSA-M Chloride anion Chemical compound [Cl-] VEXZGXHMUGYJMC-UHFFFAOYSA-M 0.000 description 1
- WHXSMMKQMYFTQS-UHFFFAOYSA-N Lithium Chemical compound [Li] WHXSMMKQMYFTQS-UHFFFAOYSA-N 0.000 description 1
- 229910002651 NO3 Inorganic materials 0.000 description 1
- ZLMJMSJWJFRBEC-UHFFFAOYSA-N Potassium Chemical compound [K] ZLMJMSJWJFRBEC-UHFFFAOYSA-N 0.000 description 1
- QAOWNCQODCNURD-UHFFFAOYSA-L Sulfate Chemical compound [O-]S([O-])(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-L 0.000 description 1
- 239000003929 acidic solution Substances 0.000 description 1
- 239000003513 alkali Substances 0.000 description 1
- 239000000908 ammonium hydroxide Substances 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 239000003729 cation exchange resin Substances 0.000 description 1
- 150000001768 cations Chemical class 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- 238000004587 chromatography analysis Methods 0.000 description 1
- 238000003869 coulometry Methods 0.000 description 1
- 229910052739 hydrogen Inorganic materials 0.000 description 1
- 239000001257 hydrogen Substances 0.000 description 1
- 229910052744 lithium Inorganic materials 0.000 description 1
- XNGIFLGASWRNHJ-UHFFFAOYSA-L phthalate(2-) Chemical compound [O-]C(=O)C1=CC=CC=C1C([O-])=O XNGIFLGASWRNHJ-UHFFFAOYSA-L 0.000 description 1
- 229910052700 potassium Inorganic materials 0.000 description 1
- 239000011591 potassium Substances 0.000 description 1
- 239000011347 resin Substances 0.000 description 1
- 229920005989 resin Polymers 0.000 description 1
- 238000011144 upstream manufacturing Methods 0.000 description 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/26—Conditioning of the fluid carrier; Flow patterns
- G01N30/28—Control of physical parameters of the fluid carrier
- G01N30/34—Control of physical parameters of the fluid carrier of fluid composition, e.g. gradient
Landscapes
- Physics & Mathematics (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Treatment Of Liquids With Adsorbents In General (AREA)
- Sampling And Sample Adjustment (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP61267632A JPH0789113B2 (ja) | 1986-11-12 | 1986-11-12 | 液体クロマトグラフイ−の方法および装置 |
| JP62080971A JPH0785078B2 (ja) | 1987-04-03 | 1987-04-03 | 陰イオン分析方法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE3738467A1 DE3738467A1 (de) | 1988-06-01 |
| DE3738467C2 true DE3738467C2 (en, 2012) | 1990-03-08 |
Family
ID=26421936
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE19873738467 Granted DE3738467A1 (de) | 1986-11-12 | 1987-11-12 | Verfahren und vorrichtung zur fluessigkeitschromatographie |
Country Status (2)
| Country | Link |
|---|---|
| US (1) | US4849110A (en, 2012) |
| DE (1) | DE3738467A1 (en, 2012) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4915843A (en) * | 1988-11-28 | 1990-04-10 | Union Oil Company Of California | Continuous displacement chromatographic method |
| US5149436A (en) * | 1988-11-28 | 1992-09-22 | Union Oil Company Of California | Continuous displacement chromatographic method |
| JP2845909B2 (ja) * | 1988-12-09 | 1999-01-13 | 株式会社日立製作所 | 液体クロマトグラフおよびそれを用いる方法 |
| US4906580A (en) * | 1989-01-25 | 1990-03-06 | Radian Corporation | Saturation monitor and process |
| WO1991003298A1 (en) * | 1989-08-31 | 1991-03-21 | Union Oil Company Of California | Continuous high performance liquid chromatography |
| US5277871A (en) * | 1989-10-20 | 1994-01-11 | Hitachi, Ltd. | Liquid chromatographic analyzer, sample feeder and prelabeling reaction treating method |
| USD353384S (en) | 1993-06-02 | 1994-12-13 | Hitachi, Ltd. | Pump for analyzing machine of liquid chromatograph |
| JP2824443B2 (ja) * | 1994-05-12 | 1998-11-11 | ティ・エフ・シィ株式会社 | 分取用液体クロマトグラフィ装置 |
| US5449461A (en) * | 1994-06-21 | 1995-09-12 | The United States Of America As Represented By The Department Of Health And Human Services | Displacement countercurrent chromatography |
| US6337021B1 (en) | 1994-12-16 | 2002-01-08 | The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Chiral separation of enantiomers by high-speed countercurrent chromatography |
| US5770083A (en) * | 1995-08-14 | 1998-06-23 | The United States Of America As Represented By The Department Of Health And Human Services | Separation of polar compounds by affinity countercurrent chromatography |
| JP3504116B2 (ja) * | 1997-08-28 | 2004-03-08 | 株式会社日立製作所 | 分析装置 |
| US6962658B2 (en) * | 2003-05-20 | 2005-11-08 | Eksigent Technologies, Llc | Variable flow rate injector |
| JP2007057420A (ja) * | 2005-08-25 | 2007-03-08 | Ias Inc | 溶液供給装置 |
| US20100242630A1 (en) * | 2007-08-05 | 2010-09-30 | Al-Qassem Sadeq Ahmad | Sample extraction device |
| US8863595B2 (en) | 2007-08-05 | 2014-10-21 | Kuwait University | Sample extraction device |
| US20090031827A1 (en) * | 2007-08-05 | 2009-02-05 | University Of Kuwait | Smart sample Extraction Device and Method |
| US10048237B2 (en) * | 2013-03-04 | 2018-08-14 | Shimadzu Corporation | Preparative separation chromatograph system |
| US11287403B2 (en) * | 2016-01-07 | 2022-03-29 | Board Of Regents, The University Of Texas System | Ion chromatography system and methods utilizing a weak acid or weak base extraction device |
| CN112710747B (zh) * | 2020-12-15 | 2022-08-02 | 山东省计量科学研究院 | 一种化学需氧量标准溶液的定值方法 |
| CN112710756A (zh) * | 2020-12-23 | 2021-04-27 | 广东省科学院生态环境与土壤研究所 | 液相色谱-原子荧光光谱联用测定三价锑和五价锑含量的方法 |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3806321A (en) * | 1971-09-02 | 1974-04-23 | Durrum Dev Corp | Fluid sample analysis system |
| US3846074A (en) * | 1972-03-22 | 1974-11-05 | Standard Oil Co | Determination of p2o5 |
| US3926559A (en) * | 1973-08-06 | 1975-12-16 | Dow Chemical Co | Method and apparatus for quantitative chromatographic analysis of cationic species |
| US4070284A (en) * | 1973-08-20 | 1978-01-24 | Hitachi, Ltd. | Liquid chromatography and apparatus for the same |
| US3923460A (en) * | 1974-11-12 | 1975-12-02 | Dow Chemical Co | Dual ion chromatograph using parallel columns for ionic analysis |
| US4112743A (en) * | 1976-09-15 | 1978-09-12 | Phillips Petroleum Company | Step-wise gradient carrier for liquid chromatography |
| JPS581383B2 (ja) * | 1979-04-04 | 1983-01-11 | 工業技術院長 | 水中アンモニウムイオンの自動測定法 |
| US4272246A (en) * | 1979-08-20 | 1981-06-09 | The United States Of America As Represented By The United States Department Of Energy | Method and apparatus for chromatographic quantitative analysis |
| US4403039A (en) * | 1980-10-29 | 1983-09-06 | Yokogawa Hokushin Electric Works | Method and apparatus for analysis of ionic species |
| US4387075A (en) * | 1981-06-08 | 1983-06-07 | Illinois Water Treatment Company | Preanalytical processing apparatus for ion exchange resin |
| US4634680A (en) * | 1983-07-14 | 1987-01-06 | International Coal Refining Company | Sequential elution process |
| US4478713A (en) * | 1983-09-23 | 1984-10-23 | Pharmuka Laboratoires | Automatic installation for liquid chromatography |
| US4592842A (en) * | 1984-03-08 | 1986-06-03 | Spectra-Physics, Inc. | Method and apparatus for optimizing peak detection in a chromatogram |
| US4654311A (en) * | 1984-06-15 | 1987-03-31 | Syntex (U.S.A.) Inc. | Serum pretreatment for digoxin assay |
| DE3442227A1 (de) * | 1984-11-19 | 1986-05-28 | Kernforschungsanlage Jülich GmbH, 5170 Jülich | Verfahren und vorrichtung zur ionenchromatographischen bestimmung des spurengehalts von waessrigen proben |
| US4732686A (en) * | 1985-12-19 | 1988-03-22 | The Dow Chemical Company | Weak eluant ion chromatography |
| JP3304137B2 (ja) * | 1992-09-25 | 2002-07-22 | 松下電工株式会社 | 表示灯付スイッチ |
-
1987
- 1987-11-12 DE DE19873738467 patent/DE3738467A1/de active Granted
- 1987-11-12 US US07/119,479 patent/US4849110A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| US4849110A (en) | 1989-07-18 |
| DE3738467A1 (de) | 1988-06-01 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| OP8 | Request for examination as to paragraph 44 patent law | ||
| D2 | Grant after examination | ||
| 8364 | No opposition during term of opposition | ||
| 8339 | Ceased/non-payment of the annual fee |