DE3673329D1 - Depolymerisierte hexosaminoglykansulfate mit antithrombogener, fibrinolytischer und entzuendungshemmender aktivitaet, verfahren zu deren herstellung und die damit zusammenhaengenden zusammensetzungen. - Google Patents

Depolymerisierte hexosaminoglykansulfate mit antithrombogener, fibrinolytischer und entzuendungshemmender aktivitaet, verfahren zu deren herstellung und die damit zusammenhaengenden zusammensetzungen.

Info

Publication number
DE3673329D1
DE3673329D1 DE8686903331T DE3673329T DE3673329D1 DE 3673329 D1 DE3673329 D1 DE 3673329D1 DE 8686903331 T DE8686903331 T DE 8686903331T DE 3673329 T DE3673329 T DE 3673329T DE 3673329 D1 DE3673329 D1 DE 3673329D1
Authority
DE
Germany
Prior art keywords
antithromogenic
hexosaminoglycan
depolymerized
fibrinolytic
sulfates
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE8686903331T
Other languages
English (en)
Inventor
Giuseppe Mascellani
Pietro Bianchini
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Opocrin SpA
Original Assignee
Opocrin SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Opocrin SpA filed Critical Opocrin SpA
Application granted granted Critical
Publication of DE3673329D1 publication Critical patent/DE3673329D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
    • C08B37/0063—Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
    • C08B37/0063—Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
    • C08B37/0075—Heparin; Heparan sulfate; Derivatives thereof, e.g. heparosan; Purification or extraction methods thereof
    • C08B37/0078—Degradation products

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Materials Engineering (AREA)
  • Molecular Biology (AREA)
  • Polymers & Plastics (AREA)
  • Biochemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Diabetes (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DE8686903331T 1985-05-17 1986-05-15 Depolymerisierte hexosaminoglykansulfate mit antithrombogener, fibrinolytischer und entzuendungshemmender aktivitaet, verfahren zu deren herstellung und die damit zusammenhaengenden zusammensetzungen. Expired - Lifetime DE3673329D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT8520769A IT1214609B (it) 1985-05-17 1985-05-17 Esosaminoglicani solfati depolimerizzati ad attivita'antitrombotica, fibrinolitica, antinfiammatoria, loro procedimento di preparazione e composizioni farmaceutiche che li contengono.
PCT/EP1986/000291 WO1986006729A1 (en) 1985-05-17 1986-05-15 Depolymerized hexosaminoglucan sulfates endowed with an antithrombotic, fibrinolytic, antiinflammatory activity, their process of preparation and related pharmaceutical compositions

Publications (1)

Publication Number Publication Date
DE3673329D1 true DE3673329D1 (de) 1990-09-13

Family

ID=11171798

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8686903331T Expired - Lifetime DE3673329D1 (de) 1985-05-17 1986-05-15 Depolymerisierte hexosaminoglykansulfate mit antithrombogener, fibrinolytischer und entzuendungshemmender aktivitaet, verfahren zu deren herstellung und die damit zusammenhaengenden zusammensetzungen.

Country Status (16)

Country Link
US (1) US4973580A (de)
EP (1) EP0221977B1 (de)
JP (1) JP2510177B2 (de)
CN (1) CN1009096B (de)
AR (1) AR240461A1 (de)
AT (1) ATE55396T1 (de)
AU (1) AU601910B2 (de)
CA (1) CA1283098C (de)
DD (1) DD251355A5 (de)
DE (1) DE3673329D1 (de)
DK (1) DK173804B1 (de)
HU (1) HU203565B (de)
IL (1) IL78772A (de)
IT (1) IT1214609B (de)
WO (1) WO1986006729A1 (de)
ZA (1) ZA863651B (de)

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KR20030069990A (ko) * 2000-09-08 2003-08-27 해밀톤 시빅 호스피탈즈 리서치 디벨로프먼트 인코포레이티드 항혈전 조성물
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Also Published As

Publication number Publication date
HUT46028A (en) 1988-09-28
CN86104301A (zh) 1987-03-04
EP0221977B1 (de) 1990-08-08
IL78772A0 (en) 1986-08-31
EP0221977A1 (de) 1987-05-20
IT8520769A0 (it) 1985-05-17
DK15787A (da) 1987-01-13
JP2510177B2 (ja) 1996-06-26
HU203565B (en) 1991-08-28
CN1009096B (zh) 1990-08-08
ATE55396T1 (de) 1990-08-15
ZA863651B (en) 1987-01-28
DK15787D0 (da) 1987-01-13
DD251355A5 (de) 1987-11-11
US4973580A (en) 1990-11-27
JPS63500184A (ja) 1988-01-21
WO1986006729A1 (en) 1986-11-20
IT1214609B (it) 1990-01-18
AU601910B2 (en) 1990-09-20
IL78772A (en) 1991-08-16
DK173804B1 (da) 2001-11-05
AR240461A1 (es) 1990-04-30
CA1283098C (en) 1991-04-16
AU5953386A (en) 1986-12-04

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