DK15787A - Depolymeriserede hexosaminoglucansulfater med en antithrombotisk, fibrinolytisk, antiinflammatorisk aktivitet, fremgangsmaade til fremstilling heraf samt farmaceutiske midler indeholdende disse - Google Patents

Depolymeriserede hexosaminoglucansulfater med en antithrombotisk, fibrinolytisk, antiinflammatorisk aktivitet, fremgangsmaade til fremstilling heraf samt farmaceutiske midler indeholdende disse

Info

Publication number
DK15787A
DK15787A DK015787A DK15787A DK15787A DK 15787 A DK15787 A DK 15787A DK 015787 A DK015787 A DK 015787A DK 15787 A DK15787 A DK 15787A DK 15787 A DK15787 A DK 15787A
Authority
DK
Denmark
Prior art keywords
sulfathes
hexosaminoglucan
antithromobotic
depolymerized
fibrinolytic
Prior art date
Application number
DK015787A
Other languages
English (en)
Other versions
DK173804B1 (da
DK15787D0 (da
Inventor
Giuseppe Mascellani
Pietro Bianchini
Original Assignee
Opocrin Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Opocrin Spa filed Critical Opocrin Spa
Publication of DK15787A publication Critical patent/DK15787A/da
Publication of DK15787D0 publication Critical patent/DK15787D0/da
Application granted granted Critical
Publication of DK173804B1 publication Critical patent/DK173804B1/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
    • C08B37/0063—Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
    • C08B37/0063—Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
    • C08B37/0075—Heparin; Heparan sulfate; Derivatives thereof, e.g. heparosan; Purification or extraction methods thereof
    • C08B37/0078—Degradation products
DK198700157A 1985-05-17 1987-01-13 Depolymeriserede naturlige hepariner, heparansulfater eller dermatansulfater med en antithrombotisk, fibrinolytisk, antiinflammatorisk aktivetet, fremgangsmåde til fremstilling heraf samt farmaceutiske midler indeholdende disse DK173804B1 (da)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
IT2076985 1985-05-17
IT8520769A IT1214609B (it) 1985-05-17 1985-05-17 Esosaminoglicani solfati depolimerizzati ad attivita'antitrombotica, fibrinolitica, antinfiammatoria, loro procedimento di preparazione e composizioni farmaceutiche che li contengono.
PCT/EP1986/000291 WO1986006729A1 (en) 1985-05-17 1986-05-15 Depolymerized hexosaminoglucan sulfates endowed with an antithrombotic, fibrinolytic, antiinflammatory activity, their process of preparation and related pharmaceutical compositions
EP8600291 1986-05-15

Publications (3)

Publication Number Publication Date
DK15787A true DK15787A (da) 1987-01-13
DK15787D0 DK15787D0 (da) 1987-01-13
DK173804B1 DK173804B1 (da) 2001-11-05

Family

ID=11171798

Family Applications (1)

Application Number Title Priority Date Filing Date
DK198700157A DK173804B1 (da) 1985-05-17 1987-01-13 Depolymeriserede naturlige hepariner, heparansulfater eller dermatansulfater med en antithrombotisk, fibrinolytisk, antiinflammatorisk aktivetet, fremgangsmåde til fremstilling heraf samt farmaceutiske midler indeholdende disse

Country Status (16)

Country Link
US (1) US4973580A (da)
EP (1) EP0221977B1 (da)
JP (1) JP2510177B2 (da)
CN (1) CN1009096B (da)
AR (1) AR240461A1 (da)
AT (1) ATE55396T1 (da)
AU (1) AU601910B2 (da)
CA (1) CA1283098C (da)
DD (1) DD251355A5 (da)
DE (1) DE3673329D1 (da)
DK (1) DK173804B1 (da)
HU (1) HU203565B (da)
IL (1) IL78772A (da)
IT (1) IT1214609B (da)
WO (1) WO1986006729A1 (da)
ZA (1) ZA863651B (da)

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CN106947004A (zh) * 2017-03-02 2017-07-14 浙江大学 一种低分子量肝素的制备方法
AU2018289438A1 (en) * 2017-06-20 2020-02-06 The Regents Of The University Of California Production of bioactive oligosaccharides
CN109748984A (zh) * 2018-12-28 2019-05-14 河北常山生化药业股份有限公司 一种那屈肝素钙制备方法
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CN114727643A (zh) * 2019-11-14 2022-07-08 Bcd生物科学有限公司 高产过氧化物淬灭控制的多糖解聚及其组合物
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Also Published As

Publication number Publication date
EP0221977B1 (en) 1990-08-08
EP0221977A1 (en) 1987-05-20
DD251355A5 (de) 1987-11-11
JP2510177B2 (ja) 1996-06-26
IL78772A0 (en) 1986-08-31
WO1986006729A1 (en) 1986-11-20
ZA863651B (en) 1987-01-28
HU203565B (en) 1991-08-28
IL78772A (en) 1991-08-16
CA1283098C (en) 1991-04-16
DE3673329D1 (de) 1990-09-13
AU5953386A (en) 1986-12-04
JPS63500184A (ja) 1988-01-21
DK173804B1 (da) 2001-11-05
IT8520769A0 (it) 1985-05-17
ATE55396T1 (de) 1990-08-15
CN86104301A (zh) 1987-03-04
US4973580A (en) 1990-11-27
AR240461A1 (es) 1990-04-30
IT1214609B (it) 1990-01-18
CN1009096B (zh) 1990-08-08
DK15787D0 (da) 1987-01-13
HUT46028A (en) 1988-09-28
AU601910B2 (en) 1990-09-20

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B1 Patent granted (law 1993)
PUP Patent expired