DE3645095C2 - Antikörper - Google Patents
AntikörperInfo
- Publication number
- DE3645095C2 DE3645095C2 DE3645095A DE3645095A DE3645095C2 DE 3645095 C2 DE3645095 C2 DE 3645095C2 DE 3645095 A DE3645095 A DE 3645095A DE 3645095 A DE3645095 A DE 3645095A DE 3645095 C2 DE3645095 C2 DE 3645095C2
- Authority
- DE
- Germany
- Prior art keywords
- polypeptide
- cells
- amino acid
- oncostatin
- amino acids
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
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- 150000001413 amino acids Chemical class 0.000 claims description 36
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- 229930182816 L-glutamine Natural products 0.000 description 1
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- 229930182555 Penicillin Natural products 0.000 description 1
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- PMZXXNPJQYDFJX-UHFFFAOYSA-N acetonitrile;2,2,2-trifluoroacetic acid Chemical compound CC#N.OC(=O)C(F)(F)F PMZXXNPJQYDFJX-UHFFFAOYSA-N 0.000 description 1
- 230000002378 acidificating effect Effects 0.000 description 1
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- 229940024546 aluminum hydroxide gel Drugs 0.000 description 1
- SMYKVLBUSSNXMV-UHFFFAOYSA-K aluminum;trihydroxide;hydrate Chemical compound O.[OH-].[OH-].[OH-].[Al+3] SMYKVLBUSSNXMV-UHFFFAOYSA-K 0.000 description 1
- 230000001621 anti-mitogenic effect Effects 0.000 description 1
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- 125000003118 aryl group Chemical group 0.000 description 1
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- WQZGKKKJIJFFOK-FPRJBGLDSA-N beta-D-galactose Chemical compound OC[C@H]1O[C@@H](O)[C@H](O)[C@@H](O)[C@H]1O WQZGKKKJIJFFOK-FPRJBGLDSA-N 0.000 description 1
- IQFYYKKMVGJFEH-UHFFFAOYSA-N beta-L-thymidine Natural products O=C1NC(=O)C(C)=CN1C1OC(CO)C(O)C1 IQFYYKKMVGJFEH-UHFFFAOYSA-N 0.000 description 1
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- 229940079322 interferon Drugs 0.000 description 1
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- XMBWDFGMSWQBCA-FTXFMUIASA-N iodane Chemical compound [122IH] XMBWDFGMSWQBCA-FTXFMUIASA-N 0.000 description 1
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- ZIHBOROHTYWINY-UHFFFAOYSA-N propan-1-ol;2,2,2-trifluoroacetic acid Chemical compound CCCO.OC(=O)C(F)(F)F ZIHBOROHTYWINY-UHFFFAOYSA-N 0.000 description 1
- 239000012264 purified product Substances 0.000 description 1
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- 229960005322 streptomycin Drugs 0.000 description 1
- 208000024891 symptom Diseases 0.000 description 1
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- 229960004072 thrombin Drugs 0.000 description 1
- 229940104230 thymidine Drugs 0.000 description 1
- CGVXVPQJMYMMIH-HKDZDBKOSA-N tigliane Chemical class C1[C@H](C)C[C@H]2[C@@H]3C(C)(C)[C@@H]3C[C@@H](C)[C@@H]2[C@@H]2C[C@H](C)C[C@H]21 CGVXVPQJMYMMIH-HKDZDBKOSA-N 0.000 description 1
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- 230000014621 translational initiation Effects 0.000 description 1
- QORWJWZARLRLPR-UHFFFAOYSA-H tricalcium bis(phosphate) Chemical compound [Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O QORWJWZARLRLPR-UHFFFAOYSA-H 0.000 description 1
- LENZDBCJOHFCAS-UHFFFAOYSA-N tris Chemical compound OCC(N)(CO)CO LENZDBCJOHFCAS-UHFFFAOYSA-N 0.000 description 1
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P21/00—Preparation of peptides or proteins
- C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/70—Fusion polypeptide containing domain for protein-protein interaction
- C07K2319/74—Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor
- C07K2319/75—Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor containing a fusion for activation of a cell surface receptor, e.g. thrombopoeitin, NPY and other peptide hormones
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biochemistry (AREA)
- Immunology (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Zoology (AREA)
- Biophysics (AREA)
- Wood Science & Technology (AREA)
- Biotechnology (AREA)
- Gastroenterology & Hepatology (AREA)
- Microbiology (AREA)
- Toxicology (AREA)
- General Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US81123585A | 1985-12-20 | 1985-12-20 | |
| US93528386A | 1986-11-26 | 1986-11-26 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE3645095C2 true DE3645095C2 (de) | 1993-11-18 |
Family
ID=27123452
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE3645095A Expired - Lifetime DE3645095C2 (de) | 1985-12-20 | 1986-12-19 | Antikörper |
| DE19863643428 Granted DE3643428A1 (de) | 1985-12-20 | 1986-12-19 | Zellwachstumsregulierende faktoren |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE19863643428 Granted DE3643428A1 (de) | 1985-12-20 | 1986-12-19 | Zellwachstumsregulierende faktoren |
Country Status (29)
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4645828A (en) * | 1984-03-23 | 1987-02-24 | Oncogen | Platelet related growth regulator |
| NZ218634A (en) * | 1985-12-20 | 1991-06-25 | Oncogen | Peptide identified by its cross reactivity with a cell growth factor, dna, antibodies to peptide and test kits |
| US5681930A (en) * | 1985-12-20 | 1997-10-28 | Bristol-Myers Squibb Company | Anti-oncostatin M monoclonal antibodies |
| NZ226799A (en) * | 1987-11-06 | 1991-08-27 | Oncogen | Breast cancer inhibitory factor and method for inhibiting proliferation of neoplastic cells and compositions therefor |
| ZA912137B (en) * | 1990-03-29 | 1992-11-25 | Oncogen | Monocional antibodies that inhibit growth of kaposi's sarcoma |
| NO303226B1 (no) * | 1990-03-29 | 1998-06-15 | Bristol Myers Squibb Co | Monoklonalt antistoff mot Onkostatin M, samt DNA-molekyl, cellelinje og hybridom |
| WO1992002556A1 (en) * | 1990-08-02 | 1992-02-20 | Michael Valentine Agrez | Human colon cancer cell-derived fibroblast elongation factor |
| IL107040A0 (en) * | 1992-09-25 | 1993-12-28 | Lilly Co Eli | Modified platelet factor-4 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4132776A (en) * | 1978-02-15 | 1979-01-02 | University Patents, Inc. | Delivery of immunologically active components of transfer factor |
| US4645828A (en) * | 1984-03-23 | 1987-02-24 | Oncogen | Platelet related growth regulator |
| NZ218634A (en) * | 1985-12-20 | 1991-06-25 | Oncogen | Peptide identified by its cross reactivity with a cell growth factor, dna, antibodies to peptide and test kits |
-
1986
- 1986-12-15 NZ NZ218634A patent/NZ218634A/en unknown
- 1986-12-16 GB GB8629997A patent/GB2185485B/en not_active Expired - Lifetime
- 1986-12-16 AU AU66608/86A patent/AU601168B2/en not_active Expired
- 1986-12-17 BE BE0/217546A patent/BE905957A/fr not_active IP Right Cessation
- 1986-12-17 LU LU86718A patent/LU86718A1/fr unknown
- 1986-12-17 FI FI865156A patent/FI91484C/fi not_active IP Right Cessation
- 1986-12-17 ES ES8603468A patent/ES2003180A6/es not_active Expired
- 1986-12-17 NL NL8603209A patent/NL8603209A/nl not_active Application Discontinuation
- 1986-12-18 DK DK198606153A patent/DK174094B1/da not_active IP Right Cessation
- 1986-12-18 SE SE8605459A patent/SE505059C2/sv not_active IP Right Cessation
- 1986-12-18 CA CA000525706A patent/CA1340296C/en not_active Expired - Lifetime
- 1986-12-18 IL IL81017A patent/IL81017A/xx not_active IP Right Cessation
- 1986-12-19 JP JP61301853A patent/JP2559035B2/ja not_active Expired - Lifetime
- 1986-12-19 FR FR868617895A patent/FR2597108B1/fr not_active Expired - Lifetime
- 1986-12-19 PT PT83986A patent/PT83986B/pt unknown
- 1986-12-19 IT IT8622787A patent/IT1213428B/it active
- 1986-12-19 IE IE334586A patent/IE59415B1/en not_active IP Right Cessation
- 1986-12-19 NO NO865178A patent/NO174556C/no not_active IP Right Cessation
- 1986-12-19 KR KR1019860010968A patent/KR920005920B1/ko not_active Expired
- 1986-12-19 CN CN86108955A patent/CN1017626B/zh not_active Expired
- 1986-12-19 HU HU865359A patent/HU210694B/hu unknown
- 1986-12-19 DE DE3645095A patent/DE3645095C2/de not_active Expired - Lifetime
- 1986-12-19 DE DE19863643428 patent/DE3643428A1/de active Granted
- 1986-12-19 OA OA59026A patent/OA08494A/xx unknown
- 1986-12-22 CH CH5119/86A patent/CH675727A5/de unknown
- 1986-12-22 AT AT0340686A patent/AT400444B/de not_active IP Right Cessation
- 1986-12-22 GR GR862936A patent/GR862936B/el unknown
-
1990
- 1990-12-05 AU AU67765/90A patent/AU639048B2/en not_active Ceased
-
1991
- 1991-07-25 SG SG608/91A patent/SG60891G/en unknown
- 1991-08-15 HK HK656/91A patent/HK65691A/xx not_active IP Right Cessation
-
1992
- 1992-04-03 CY CY1608A patent/CY1608A/en unknown
Non-Patent Citations (1)
| Title |
|---|
| NICHTS ERMITTELT * |
Also Published As
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