DE3486453T2 - Monoklonale Antikörper gegen neue Faktor-VIII Gerinnungspolypeptide - Google Patents

Monoklonale Antikörper gegen neue Faktor-VIII Gerinnungspolypeptide

Info

Publication number
DE3486453T2
DE3486453T2 DE3486453T DE3486453T DE3486453T2 DE 3486453 T2 DE3486453 T2 DE 3486453T2 DE 3486453 T DE3486453 T DE 3486453T DE 3486453 T DE3486453 T DE 3486453T DE 3486453 T2 DE3486453 T2 DE 3486453T2
Authority
DE
Germany
Prior art keywords
polypeptides
reacts
factor viii
those
react
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE3486453T
Other languages
English (en)
Other versions
DE3486453D1 (de
Inventor
Theodore S Zimmerman
Carol A Fulcher
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Scripps Research Institute
Original Assignee
Scripps Research Institute
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27046849&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE3486453(T2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Scripps Research Institute filed Critical Scripps Research Institute
Application granted granted Critical
Publication of DE3486453D1 publication Critical patent/DE3486453D1/de
Publication of DE3486453T2 publication Critical patent/DE3486453T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/745—Blood coagulation or fibrinolysis factors
    • C07K14/755—Factors VIII, e.g. factor VIII C (AHF), factor VIII Ag (VWF)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/36—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against blood coagulation factors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Genetics & Genomics (AREA)
  • Public Health (AREA)
  • Immunology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Separation Of Suspended Particles By Flocculating Agents (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
DE3486453T 1983-03-31 1984-04-02 Monoklonale Antikörper gegen neue Faktor-VIII Gerinnungspolypeptide Expired - Lifetime DE3486453T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US48110583A 1983-03-31 1983-03-31
US55650883A 1983-11-30 1983-11-30

Publications (2)

Publication Number Publication Date
DE3486453D1 DE3486453D1 (de) 1997-08-21
DE3486453T2 true DE3486453T2 (de) 1998-02-26

Family

ID=27046849

Family Applications (2)

Application Number Title Priority Date Filing Date
DE3486453T Expired - Lifetime DE3486453T2 (de) 1983-03-31 1984-04-02 Monoklonale Antikörper gegen neue Faktor-VIII Gerinnungspolypeptide
DE3486423T Expired - Lifetime DE3486423T3 (de) 1983-03-31 1984-04-02 Neue Faktor VIII Polypeptidkoagulantien

Family Applications After (1)

Application Number Title Priority Date Filing Date
DE3486423T Expired - Lifetime DE3486423T3 (de) 1983-03-31 1984-04-02 Neue Faktor VIII Polypeptidkoagulantien

Country Status (12)

Country Link
EP (3) EP0123945B2 (de)
JP (2) JPH0829089B2 (de)
AT (2) ATE135400T1 (de)
AU (1) AU572128B2 (de)
CA (1) CA1341506C (de)
DE (2) DE3486453T2 (de)
DK (2) DK172036B1 (de)
FI (1) FI841281A (de)
IE (2) IE80858B1 (de)
NO (1) NO167533C (de)
SG (2) SG49675A1 (de)
ZA (1) ZA842418B (de)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4657894A (en) * 1983-03-31 1987-04-14 Scripps Clinic & Research Foundation New factor VIII coagulant polypeptides
DE152746T1 (de) * 1984-01-12 1986-04-10 Chiron Corp., Emeryville, Calif. Monoklonale antikoerper gegen faktor-viii-c.
DK165506C (da) * 1984-01-12 1993-04-19 Chiron Corp Proteinpraeparat med koagulationsaktivitet samt fremgangsmaade til fremstilling deraf
US5045455A (en) * 1984-01-12 1991-09-03 Chiron Corporation Factor VIII:C cDNA cloning and expression
US4716117A (en) * 1984-10-26 1987-12-29 Chiron Corporation Monoclonal antibodies to factor VIIIC
US7138505B1 (en) 1984-01-12 2006-11-21 Novartis Vaccines And Diagnostics, Inc. Factor VIII:C nucleic acid molecules
US5004804A (en) * 1984-01-12 1991-04-02 Nordisk Gentofte Method and composition for preparation of factor VIIIC
US4965199A (en) * 1984-04-20 1990-10-23 Genentech, Inc. Preparation of functional human factor VIII in mammalian cells using methotrexate based selection
IL74909A (en) * 1984-04-20 1992-01-15 Genentech Inc Preparation of functional human factor viii and dna sequences,expression vectors,transformed microorganisms and cell lines used therein
SE8501050D0 (sv) * 1985-03-05 1985-03-05 Kabivitrum Ab Biologically active fragments of human antihemophilic factor and method for preparation thereof
KR910006424B1 (ko) * 1985-08-21 1991-08-24 인코텍스 비.브이 편성브리프(brief) 제조방법
WO1988000210A1 (en) * 1986-06-24 1988-01-14 Nordisk Gentofte A/S A process for producing a coagulation active complex of factor viii fragments
CA1339946C (en) * 1987-03-31 1998-07-07 Michael J. Griffith Ultrapurification process for polypeptides
EP0690126B1 (de) 1987-06-12 2001-11-28 Baxter Aktiengesellschaft Proteine mit Faktor VIII Aktivität, Verfahren zu deren Herstellung unter Verwendung von genetisch modifizierten Zellen und diese enthaltende Zusammensetzungen
IL88309A0 (en) * 1987-11-17 1989-06-30 Scripps Clinic Res Peptides for use in the purification of factor viii
FR2662166A1 (fr) * 1990-05-18 1991-11-22 Fondation Nale Transfusion San Procede de preparation de facteur viii de tres haute purete comprenant une etape rapide d'immunoadsorption.
WO1995003332A1 (en) * 1993-07-23 1995-02-02 Baxter International Inc. Activated human factor viii and method of preparation
US5576291A (en) * 1993-09-13 1996-11-19 Baxter International Inc. Activated factor VIII as a therapeutic agent and method of treating factor VIII deficiency
CN100553678C (zh) 1999-02-22 2009-10-28 巴克斯特国际有限公司 新的无白蛋白的因子ⅷ制剂
EP1418810A4 (de) 2001-08-03 2006-08-02 Us Gov Health & Human Serv Orale behandlung von hämophilie
ES2706296T3 (es) 2008-11-07 2019-03-28 Univ Connecticut Formulaciones de Factor VIII
BRPI1105317A2 (pt) 2011-01-24 2013-04-30 Fundacco Hemoct De Ribeirco Preto produÇço estÁvel e em larga escala de fviii humano em linhagem celular humana sk-hep-1

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4364937A (en) * 1980-01-08 1982-12-21 Ortho Pharmaceutical Corporation Monoclonal antibody to a human T cell antigen and methods of preparing same
US4364936A (en) * 1980-01-08 1982-12-21 Ortho Pharmaceutical Corporation Monoclonal antibody to a human monocyte antigen and methods of preparing same
US4361509A (en) * 1981-12-14 1982-11-30 Scripps Clinic And Research Foundation Ultrapurification of factor VIII using monoclonal antibodies
US4397841A (en) * 1982-06-28 1983-08-09 Monsanto Company Production of blood coagulation factor VIII:C

Also Published As

Publication number Publication date
IE80858B1 (en) 1999-04-21
JPS59184130A (ja) 1984-10-19
DK50497A (da) 1997-05-02
AU572128B2 (en) 1988-05-05
ZA842418B (en) 1984-11-28
IE960783L (en) 1984-09-30
DE3486423T2 (de) 1996-09-19
EP0123945A1 (de) 1984-11-07
DK172036B1 (da) 1997-09-22
ATE135400T1 (de) 1996-03-15
JPH0638790A (ja) 1994-02-15
JPH0829089B2 (ja) 1996-03-27
NO167533B (no) 1991-08-05
NO167533C (no) 1991-11-13
DE3486453D1 (de) 1997-08-21
EP0770396A2 (de) 1997-05-02
DK174984A (da) 1984-10-01
DE3486423T3 (de) 2001-02-08
SG49675A1 (en) 1998-06-15
CA1341506C (en) 2006-06-06
DE3486423D1 (de) 1996-04-18
ATE155490T1 (de) 1997-08-15
IE80638B1 (en) 1998-10-21
FI841281A (fi) 1984-10-01
IE840788L (en) 1984-09-30
EP0561427A1 (de) 1993-09-22
EP0561427B1 (de) 1997-07-16
AU2627284A (en) 1984-10-04
DK174984D0 (da) 1984-03-30
NO841277L (no) 1984-10-01
EP0770396A3 (de) 1997-07-23
EP0123945B2 (de) 2000-04-19
FI841281A0 (fi) 1984-03-30
EP0123945B1 (de) 1996-03-13
SG48229A1 (en) 1998-04-17

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8363 Opposition against the patent