DK50497A - Monoklonale antistoffer over for nye faktor VIII-koaguleringspolypeptider - Google Patents

Monoklonale antistoffer over for nye faktor VIII-koaguleringspolypeptider Download PDF

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Publication number
DK50497A
DK50497A DK050497A DK50497A DK50497A DK 50497 A DK50497 A DK 50497A DK 050497 A DK050497 A DK 050497A DK 50497 A DK50497 A DK 50497A DK 50497 A DK50497 A DK 50497A
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DK
Denmark
Prior art keywords
polypeptides
reacts
factor viii
those
react
Prior art date
Application number
DK050497A
Other languages
English (en)
Inventor
Theodore S Zimmerman
Carol A Fulcher
Original Assignee
Scripps Clinic Res
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27046849&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK50497(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Scripps Clinic Res filed Critical Scripps Clinic Res
Publication of DK50497A publication Critical patent/DK50497A/da

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/745Blood coagulation or fibrinolysis factors
    • C07K14/755Factors VIII, e.g. factor VIII C (AHF), factor VIII Ag (VWF)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/36Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against blood coagulation factors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Veterinary Medicine (AREA)
  • Genetics & Genomics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Diabetes (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Separation Of Suspended Particles By Flocculating Agents (AREA)
DK050497A 1983-03-31 1997-05-02 Monoklonale antistoffer over for nye faktor VIII-koaguleringspolypeptider DK50497A (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US48110583A 1983-03-31 1983-03-31
US55650883A 1983-11-30 1983-11-30

Publications (1)

Publication Number Publication Date
DK50497A true DK50497A (da) 1997-05-02

Family

ID=27046849

Family Applications (2)

Application Number Title Priority Date Filing Date
DK174984A DK172036B1 (da) 1983-03-31 1984-03-30 Faktor VIII:C-koaguleringsmiddel, fremgangsmåde til fremstilling heraf samt fremgangsmåde til udvinding heraf
DK050497A DK50497A (da) 1983-03-31 1997-05-02 Monoklonale antistoffer over for nye faktor VIII-koaguleringspolypeptider

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DK174984A DK172036B1 (da) 1983-03-31 1984-03-30 Faktor VIII:C-koaguleringsmiddel, fremgangsmåde til fremstilling heraf samt fremgangsmåde til udvinding heraf

Country Status (12)

Country Link
EP (3) EP0770396A3 (da)
JP (2) JPH0829089B2 (da)
AT (2) ATE135400T1 (da)
AU (1) AU572128B2 (da)
CA (1) CA1341506C (da)
DE (2) DE3486423T3 (da)
DK (2) DK172036B1 (da)
FI (1) FI841281A (da)
IE (2) IE80638B1 (da)
NO (1) NO167533C (da)
SG (2) SG48229A1 (da)
ZA (1) ZA842418B (da)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4657894A (en) * 1983-03-31 1987-04-14 Scripps Clinic & Research Foundation New factor VIII coagulant polypeptides
US5045455A (en) * 1984-01-12 1991-09-03 Chiron Corporation Factor VIII:C cDNA cloning and expression
US7138505B1 (en) 1984-01-12 2006-11-21 Novartis Vaccines And Diagnostics, Inc. Factor VIII:C nucleic acid molecules
DE3588242T2 (de) * 1984-01-12 2004-03-11 Chiron Corp. (N.D.Ges.D. Staates Delaware), Emeryville Für Faktor-VIIIc kodierende DNA-Sequenzen und verwandte DNA-Konstruktionen
JPH0764879B2 (ja) * 1984-01-12 1995-07-12 チロン コ−ポレイシヨン フアクタ−v▲iii▼cに対するモノクロ−ナル抗体
US4716117A (en) * 1984-10-26 1987-12-29 Chiron Corporation Monoclonal antibodies to factor VIIIC
US5004804A (en) * 1984-01-12 1991-04-02 Nordisk Gentofte Method and composition for preparation of factor VIIIC
US4965199A (en) * 1984-04-20 1990-10-23 Genentech, Inc. Preparation of functional human factor VIII in mammalian cells using methotrexate based selection
FI86885C (fi) * 1984-04-20 1992-10-26 Genentech Inc Foerfarande foer framstaellning av human rekombinantfaktor viii och nukleinsyrasekvenser och vektorer anvaend daertill
SE8501050D0 (sv) * 1985-03-05 1985-03-05 Kabivitrum Ab Biologically active fragments of human antihemophilic factor and method for preparation thereof
KR910006424B1 (ko) * 1985-08-21 1991-08-24 인코텍스 비.브이 편성브리프(brief) 제조방법
JP2593500B2 (ja) * 1986-06-24 1997-03-26 ノルデイスク ゲントフテ エー/エス ▲viii▼因子フラグメントの凝固活性複合物の製造方法
CA1339946C (en) * 1987-03-31 1998-07-07 Michael J. Griffith Ultrapurification process for polypeptides
EP0690126B1 (en) 1987-06-12 2001-11-28 Baxter Aktiengesellschaft Novel proteins with factor VIII activitiy: process for their preparation using genetically-engineered cells and pharmaceutical compositions containing them
IL88309A0 (en) * 1987-11-17 1989-06-30 Scripps Clinic Res Peptides for use in the purification of factor viii
FR2662166A1 (fr) * 1990-05-18 1991-11-22 Fondation Nale Transfusion San Procede de preparation de facteur viii de tres haute purete comprenant une etape rapide d'immunoadsorption.
AU7254894A (en) * 1993-07-23 1995-02-20 Baxter International Inc. Activated human factor viii and method of preparation
US5576291A (en) * 1993-09-13 1996-11-19 Baxter International Inc. Activated factor VIII as a therapeutic agent and method of treating factor VIII deficiency
EP1154796B1 (en) 1999-02-22 2007-06-20 University of Connecticut Novel albumin-free factor viii formulations
US7220718B2 (en) 2001-08-03 2007-05-22 United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Oral treatment of hemophilia
BRPI0921429B1 (pt) 2008-11-07 2022-07-12 Takeda Pharmaceutical Company Limited Formulação farmacêutica liofilizada estável, e, método para preparar um fator liofilizado estável
BRPI1105317A2 (pt) 2011-01-24 2013-04-30 Fundacco Hemoct De Ribeirco Preto produÇço estÁvel e em larga escala de fviii humano em linhagem celular humana sk-hep-1

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4364936A (en) * 1980-01-08 1982-12-21 Ortho Pharmaceutical Corporation Monoclonal antibody to a human monocyte antigen and methods of preparing same
US4364937A (en) * 1980-01-08 1982-12-21 Ortho Pharmaceutical Corporation Monoclonal antibody to a human T cell antigen and methods of preparing same
US4361509A (en) * 1981-12-14 1982-11-30 Scripps Clinic And Research Foundation Ultrapurification of factor VIII using monoclonal antibodies
US4397841A (en) * 1982-06-28 1983-08-09 Monsanto Company Production of blood coagulation factor VIII:C

Also Published As

Publication number Publication date
NO841277L (no) 1984-10-01
DE3486423D1 (de) 1996-04-18
CA1341506C (en) 2006-06-06
IE840788L (en) 1984-09-30
EP0561427B1 (en) 1997-07-16
EP0770396A2 (en) 1997-05-02
IE80858B1 (en) 1999-04-21
IE960783L (en) 1984-09-30
ATE135400T1 (de) 1996-03-15
DK172036B1 (da) 1997-09-22
EP0561427A1 (en) 1993-09-22
FI841281A0 (fi) 1984-03-30
SG48229A1 (en) 1998-04-17
EP0770396A3 (en) 1997-07-23
ATE155490T1 (de) 1997-08-15
JPH0638790A (ja) 1994-02-15
IE80638B1 (en) 1998-10-21
NO167533B (no) 1991-08-05
EP0123945A1 (en) 1984-11-07
AU2627284A (en) 1984-10-04
DE3486453T2 (de) 1998-02-26
JPS59184130A (ja) 1984-10-19
DE3486453D1 (de) 1997-08-21
DE3486423T2 (de) 1996-09-19
ZA842418B (en) 1984-11-28
SG49675A1 (en) 1998-06-15
AU572128B2 (en) 1988-05-05
EP0123945B1 (en) 1996-03-13
DK174984A (da) 1984-10-01
NO167533C (no) 1991-11-13
JPH0829089B2 (ja) 1996-03-27
EP0123945B2 (en) 2000-04-19
DK174984D0 (da) 1984-03-30
DE3486423T3 (de) 2001-02-08
FI841281A (fi) 1984-10-01

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